Clinical trials: Anxiety, Generalized
Anxiety Disorders, Mental Health
St. John's Wort for the Treatment of Generalized Social Anxiety Disorder (GSAD)
This study will determine whether the herbal product St. John's wort is safe and effective in treating generalized social anxiety disorder (GSAD). Study hypothesis: Hypericum perforatum (St.
- Trial name
- NCT00118833
- Testing
- Hypericum perforatum (St. John's wort)
- Where
- United States
- Volunteers
- 56 people
- Sponsor
- National Center for Complementary and Integrative Health (NCCIH)
Generalized Anxiety Disorder (GAD), Social Anxiety Disorder (SAD)
Stepped Care Treatment for Anxiety Resilience
Childhood anxiety disorders (CAD) are common and impairing. Family based cognitive behavioral therapy (CBT) is efficacious in treating CAD.
- Conditions
- Generalized Anxiety Disorder (GAD), Social Anxiety Disorder (SAD), Separation Anxiety Disorder, Specific Phobia
- Trial name
- STAR (NCT07228143)
- Testing
- Relaxation and Mentorship Training (RMT), Stepped Care Targeting Exposure and Parenting for Anxiety (STEP-A)
- Where
- United States
- Volunteers
- 106 people
- Sponsor
- Andrew Wiese
Generalized Anxiety Disorder
Transcranial Magnetic Stimulation Treatment for Generalized Anxiety Disorder
This study is investigating a new indication of Transcranial Magnetic Stimulation (TMS) by conducting a pilot randomized-controlled trial (RCT) comparing structural neuronavigation-directed TMS to Sham-TMS Placebo therapy for…
- Trial name
- NCT01659736
- Testing
- TMS
- Where
- United States
- Volunteers
- 26 people
- Sponsor
- Hartford Hospital
Generalized Anxiety Disorder
The Comparative Clinical Study of Gamisoyosan on Anxiety of Generalized Anxiety Disorder According to Dosage Form
In this randomized, double blinded, Parallel-controlled study, the investigators planned to give Gamisoyosan extract, Gamisoyosan extract powder or controlled medication on Anxiety of generalized anxiety disorder according to…
- Trial name
- NCT01285115
- Testing
- KyungBangn-Gamisoyosan-x-gwarip, KyungBangn Gamisoyosan
- Where
- South Korea
- Volunteers
- 147 people, healthy volunteers welcome
- Sponsor
- Korea Health Industry Development Institute
Generalized Anxiety Disorder
Cognitive Behavioral Therapy (CBT) for Late Life Anxiety
The purpose of this research study is to assess the acceptability and feasibility of the implementation strategy and fidelity of cognitive-behavioral therapy (CBT) for older adults with Generalized Anxiety Disorder.
- Trial name
- NCT05380115
- Testing
- Cognitive Behavioral Therapy (CBT)
- Sponsor
- Wake Forest University Health Sciences
Schizophrenia Disorders, Major Depression
Non-Coding RNAs Gene Expression in Psychiatric Disorders
This study aims to investigate whether specific non-coding RNAs, molecules involved in the regulation of gene expression, are altered in individuals with psychiatric disorders such as schizophrenia, bipolar disorder, major…
- Conditions
- Schizophrenia Disorders, Major Depression, Bipolar Affective Disorders, Obsessive Compulsive Disorder (OCD)
- Trial name
- PsiRNA26 (NCT07649993)
- Testing
- Reverse Transcription Quantitative Polymerase Chain Reaction
- Where
- 5 sites in Italy
- Volunteers
- 384 people, healthy volunteers welcome
- Sponsor
- Carmen Concerto
Major Depressive Disorder (MDD), SCHIZOPHRENIA 1 (Disorder)
Transcranial Direct Current Stimulation (tDCS) in Different Psychiatric Disorders
The goal of this clinical trial is to evaluate the efficacy and safety of transcranial direct current stimulation (tDCS) in reducing core symptoms of different psychiatric disorders using validated clinical scales.
- Conditions
- Major Depressive Disorder (MDD), SCHIZOPHRENIA 1 (Disorder), Obsessive-Compulsive Disorder, Generalized Anxiety Disorder
- Trial name
- Transcranial (NCT07452835)
- Testing
- tDCS Parameters
- Where
- Egypt
- Volunteers
- 320 people
- Sponsor
- Menoufia University
Nutrition Knowledge, Generalized Anxiety Disorder (GAD)
Digital Versus Hybrid Interventions in Promoting Nutrition Knowledge Among Saudi Adolescent Girls
This study primarily aims to compare the efficacy of different approaches to nutrition education intervention delivery in improving nutrition knowledge (NK) among Saudi adolescent girls.
- Conditions
- Nutrition Knowledge, Generalized Anxiety Disorder (GAD), Food Habits, Body Mass Index
- Trial name
- NCT06836336
- Testing
- Hybrid therapy, Fully digital
- Where
- Saudi Arabia
- Volunteers
- 104 people, healthy volunteers welcome
- Sponsor
- Umm Al-Qura University
Anxiety Disorders
Prevention of Relapse Study of SR58611A in Improved Patients With Generalized Anxiety Disorder
The purpose of the study is to evaluate the efficacy and safety of SR58611A (350 mg BID) compared to placebo in the prevention of relapse of anxiety, in patients with Generalized Anxiety Disorder improved after 12 weeks of…
- Trial name
- VEGA (NCT00397098)
- Testing
- SR58611A
- Where
- 9 sites in Australia, Chile and 7 more
- Volunteers
- 257 people
- Sponsor
- Sanofi
End Stage Renal Disease, Depression
Music Therapy and Dialysis: A Pilot Investigation Into the Effectiveness of Patient-Selected Music Interventions on Physiological, Psychological, and Quality-of-Life Outcomes
The objective of this study is to determine the effect of music therapy during dialysis on: depression, anxiety, quality of life, blood pressure, heart rate, medication compliance, compliance with dialysis treatment, number of…
- Conditions
- End Stage Renal Disease, Depression, Anxiety, Major Depressive Disorder
- Trial name
- NCT03925168
- Testing
- Music therapy
- Where
- 3 sites in United States
- Volunteers
- 50 people
- Sponsor
- Tulane University
Generalized Anxiety Disorder
An Open-label Study to Investigate the Absorption, Metabolism and Excretion of Radiolabeled PD 0332334 in Six Healthy Male Volunteers
The purpose of this study is to investigate the absorption, metabolism and excretion of [14C] PD 0332334 to characterize plasma, fecal and urinary radioactivity and identify any metabolites of [14C] PD 0332334.
- Trial name
- NCT00537615
- Testing
- PD 0332334
- Where
- United States
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- Pfizer
Generalized Anxiety Disorder, Separation Anxiety Disorder
Attention Bias Modification Treatment for Anxious Youth
The purpose of this project is to study the feasibility and efficacy of attention bias modification treatment (ABMT) in a randomized-controlled sample of anxious youth.
- Conditions
- Generalized Anxiety Disorder, Separation Anxiety Disorder, Social Phobia, Specific Phobia
- Trial name
- ABMT (NCT01979263)
- Testing
- Attention Bias Modification Computer Task
- Where
- 2 sites in United States
- Volunteers
- 5 people
- Sponsor
- Weill Medical College of Cornell University
Anxiety, Social Anxiety Disorder
Neurofeedback Enhanced Cognitive Reappraisal Training
This study seeks to understand emotion regulation in those with anxiety using real-time functional magnetic resonance imaging neurofeedback, a tool that allows individuals to control brain activity.
- Conditions
- Anxiety, Social Anxiety Disorder, Panic Disorder, Generalized Anxiety Disorder
- Trial name
- NCT06132659
- Testing
- Functional magnetic resonance imaging (fMRI) with Veritable-NF
- Where
- United States
- Volunteers
- 21 people
- Sponsor
- University of Michigan
Social Phobia, Social Anxiety Disorder
Intranasal PH94B for Management of the Symptoms of Generalized Social Phobia
The purpose of this study is to determine the efficacy of PH94B, a new class of therapeutic compound, administered intranasally for the management of acute anxiety in patients diagnosed with generalized social phobia.
- Trial name
- PH94B-SAD (NCT01217788)
- Testing
- PH94B intranasal spray
- Where
- United States
- Volunteers
- 90 people
- Sponsor
- Pherin Pharmaceuticals, Inc.
Generalized Anxiety Disorder
Comparing Cognitive Behaviour Therapy (CBT) With Metacognitive Therapy (MCT) in the Treatment of GAD
Meta Cognitive Therapy (MCT) has been introduced as a new specific treatment for generalised anxiety disorder. So far, no studies have examined CBT and MCT in comparison with each other in a randomised controlled trial.
- Trial name
- NCT00426426
- Testing
- Cognitive-Behavioural Therapy, Meta-Cognitive Therapy, Waiting list
- Where
- Norway
- Volunteers
- 68 people, healthy volunteers welcome
- Sponsor
- Norwegian University of Science and Technology
Generalized Anxiety Disorder (GAD), Depressive and Anxiety Disorders
Miles for Mental Health
Common mental health disorders, like anxiety and depression, are widespread among the American population. The prevalence of mental health disorders among adults continues has consistently increased from previous decades and is…
- Trial name
- NCT07541443
- Testing
- Exercise
- Volunteers
- 20 people
- Sponsor
- Emporia State University
Anesthesia, ASA Physical Status I
Descriptive Observational Study of Patient-performed Pre-oxygenation
The aim of this research would be to determine the efficacy and effects of preoxygenation when performed by the patient (mask held by the patient). This is the concept of "self-preoxygenation".
- Conditions
- Anesthesia, ASA Physical Status I, ASA Physical Status II
- Trial name
- ApréOx (NCT06361693)
- Testing
- Auto-preoxygenation, APAIS scale, Visual analog anxiety scale (VAS-A)
- Where
- France
- Volunteers
- 110 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Generalized Anxiety Disorder
A Pilot Study of Cranial Electrotherapy Stimulation[CES] for Generalized Anxiety Disorder
Cranial electrotherapy stimulation(CES) is a noninvasive procedure that has been used for decades in the United States to treat anxiety, depression, and insomnia in the general population.
- Trial name
- NCT00539357
- Testing
- Cranial electrotherapy stimulation (CES)
- Volunteers
- 12 people
- Sponsor
- University of California, Los Angeles
Depression, Anxiety Disorders
Prospective Study of the Evaluation of Disease contRol and the Quality of Life of Patients With depressiOn and With or Without aNxiety disOrders in the Greek populatIon
Depression is a psychiatric disorder that affects mood, thoughts and is usually accompanied by physical annoyances. It affects the person's eating habits, his sleep, the way he sees himself and the way he thinks and understands.
- Trial name
- PRONOI (NCT03317262)
- Where
- Greece
- Volunteers
- 800 people
- Sponsor
- Elpen Pharmaceutical Co. Inc.
Major Depressive Disorder (MDD), Generalized Anxiety Disorder (GAD)
Validation of the CIDI 5.0 Against the SCID-5 for Lifetime Mental Disorders
The World Health Organization Composite International Diagnostic Interview (CIDI) is a fully structured diagnostic tool designed for lay interviewers to assess the prevalence of mental and substance use disorders.
- Conditions
- Major Depressive Disorder (MDD), Generalized Anxiety Disorder (GAD), Posttraumatic Stress Disorder (PTSD)
- Trial name
- NCT07604753
- Testing
- CIDI-5
- Where
- Hong Kong
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- The University of Hong Kong