Clinical trials: Anxiety, Generalized
Generalized Anxiety Disorder
Randomized Clinical Trial of a Mindfulness Based Intervention in Generalized Anxiety Disorder
The literature suggests that Mindfulness Based Intervention may be effective in the treatment of anxiety symptoms. The objective of this study is to compare the clinical effectiveness of a Mindfulness Based Intervention - the…
- Trial name
- NCT03072264
- Testing
- Body in Mind Training (BMT), Fluoxetine, Quality of Life Group
- Where
- Brazil
- Volunteers
- 200 people
- Sponsor
- Hospital de Clinicas de Porto Alegre
Generalized Anxiety Disorder, Social Anxiety Disorder
Predicting Treatment Response to Exposure Therapy Using Carbon Dioxide
Anxiety disorders affect over a quarter of the population, yet very little is known about the variables that predict treatment outcome.
- Conditions
- Generalized Anxiety Disorder, Social Anxiety Disorder, Panic Disorder, Agoraphobia
- Trial name
- NCT03925987
- Testing
- Exposure therapy
- Where
- United States
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Laureate Institute for Brain Research, Inc.
Anxiety, Generalized Anxiety Disorder
Comparing the Efficacy of E-CBT to Mental Health Coaching for GAD
This study will compare the efficacy of an electronically-delivered cognitive behavioural therapy (e-CBT) program versus a mental health coaching program to treat generalized anxiety disorder (GAD).
- Trial name
- NCT04754438
- Testing
- e-CBT, Mental Health Coaching
- Where
- Canada
- Volunteers
- 96 people
- Sponsor
- Dr. Nazanin Alavi
Magnetic Resonance Imaging
The Use of a Mock MRI Scanner for Reducing the Use of Anesthesia in Children Undergoing Clinical MRI Scans
Diagnostic Magnetic Resonance (MR) imaging procedures can be stressful for children and parents. Patients must lie still during the procedure to provide diagnostic quality images.
- Trial name
- NCT02630342
- Testing
- Mock MRI scanner, Preparation materials, Child Life Specialist preparation
- Where
- Canada
- Volunteers
- 160 people
- Sponsor
- University of Calgary
Dementia, Neurocognitive Disorders
Cognitive Stimulation in Older Adults With Alzheimer's Disease
This multicentre study, employing a randomised controlled repeated measures experimental design, will be conducted in several Portuguese institutions that provide care and support services for older adults diagnosed with mild to…
- Conditions
- Dementia, Neurocognitive Disorders, Cognitive Impairment, Cognitive Dysfunction
- Trial name
- NCT07041008
- Testing
- Digital intervention, Physical/Analogue Intervention
- Where
- 39 sites in Portugal
- Volunteers
- 514 people
- Sponsor
- Rsocialform - Geriatria, Lda
Post-Traumatic Stress Disorders, Major Depressive Disorder
Repeated Ketamine Infusions for Comorbid PTSD and MDD in Veterans
Co-occurring post-traumatic stress disorder (PTSD) and major depressive disorder (MDD) is the most common response to trauma; it is associated with poor clinical outcomes and substantial human disability.
- Trial name
- NCT04032301
- Testing
- Ketamine, Normal Saline
- Where
- United States
- Volunteers
- 67 people, healthy volunteers welcome
- Sponsor
- University of Minnesota
PTSD, Generalized Anxiety Disorder
Feasibility and ML Training Investigation of the Senseye DT for Diagnosis of Adults with PTSD
The aim of this study is to obtain data on the feasibility of the Senseye Diagnostic Tool (DT) to assess the presence and severity of post-traumatic stress disorder (PTSD) symptoms.
- Conditions
- PTSD, Generalized Anxiety Disorder, Major Depressive Disorder
- Trial name
- NCT05717439
- Testing
- CAPS-5-R, Senseye DT
- Where
- 5 sites in United States
- Volunteers
- 338 people, healthy volunteers welcome
- Sponsor
- Senseye, Inc.
Generalized Anxiety Disorder (GAD)
Therapeutic Effect of Neuromodulation on Anxiety Disorders by High-Definition Transcranial Electrical Stimulation
High-definition transcranial electrical stimulation (HD-tES) is a non-invasive brain neuromodulation technique that applies a small electrical current to the scalp to alter neural excitability and stimulate localized brain…
- Trial name
- NCT06775145
- Testing
- HD-R_cDC+cTBS & HD-L_aDC+iTBS
- Volunteers
- 100 people
- Sponsor
- National Taiwan University Hospital
Anxiety Disorder, Anxiety Disorder of Childhood
Web-based Attention Bias Modification Treatment for Childhood Anxiety Disorders
Anxiety disorders are the most common childhood psychiatric disorders, with prevalence rates as high as 15% to 20%. Success rates of the first choice treatment strategy (i.e. Cognitive Behavioural Therapy; CBT) are around 50%.
- Conditions
- Anxiety Disorder, Anxiety Disorder of Childhood, Separation Anxiety Disorder of Childhood, Early Onset, Specific Phobia
- Trial name
- ATTENTIO (NCT03764644)
- Testing
- Combined ABMT and CBT
- Where
- Netherlands
- Volunteers
- 55 people
- Sponsor
- Erasmus Medical Center
Generalized Anxiety Disorder
A Trial of the Efficacy and Safety of a Fixed Dose of SEP-363856 in Adults With Generalized Anxiety Disorder
This is a global, phase 3, randomized, double-blind, parallel-group, 2-arm, placebo controlled, multicenter trial designed to compare the efficacy, safety and tolerability of a fixed dose of SEP-363856 (75 millligrams per day…
- Trial name
- NCT07767903
- Testing
- SEP-363856
- Where
- 11 sites in United States
- Volunteers
- 384 people
- Sponsor
- Otsuka Pharmaceutical Development & Commercialization, Inc.
Behavior Problems, Pediatrics
Postoperative Behavioral Changes in Children.
In children scheduled for dental treatment, negative thoughts can lead to anxiety and make them resistant to treatment techniques.
- Conditions
- Behavior Problems, Pediatrics, Pediatric Pain and Anxiety
- Trial name
- NCT06761833
- Where
- Turkey (Türkiye)
- Volunteers
- 260 people, healthy volunteers welcome
- Sponsor
- Baskent University
Generalized Anxiety Disorder
The Effect of Psychoeducation Based on Acceptance and Commitment Therapy Applied to Patients Diagnosed With Generalized Anxiety Disorder on Cognitive Avoidance Levels and Coping Attitudes
This study will be conducted to determine the effects of acceptance and commitment therapy-based psychoeducation on cognitive avoidance levels and coping attitudes in patients diagnosed with generalized anxiety disorder.
- Trial name
- NCT06972563
- Testing
- Psychoeducation Based on Acceptance and Commitment Therapy Applied to Patients Diagnosed with Generalized Anxiety Disorder, The initiative was not implemented.
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Arzu Çalışkan
Pharmacokinetics
A Phased Clinical Trial of Dietary Supplemental Kava: Kava Pharmacokinetics
Kava is a dietary supplement on the US market and is experiencing a resurgence of its use. Its pharmacokinetic information, however, is lacking which is important for its future effective usage as a dietary supplement or…
- Trial name
- KavaPK (NCT03843502)
- Testing
- Kava Dietary Supplement
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- University of Florida
Fear of Spiders, Fear of Heights
Generalized Fear Extinction to Untreated Fear Stimuli in Specific Phobias After Exposure
This study investigates whether a one-session exposure treatment for spider-related stimuli can lead to a generalization of extinguished fear to height-related stimuli in individuals with comorbid fear of spiders and fear of…
- Trial name
- NCT03907345
- Testing
- Exposure
- Where
- Germany
- Volunteers
- 50 people
- Sponsor
- Ruhr University of Bochum
Autism Spectrum Disorder, Autism
Internet-delivered Cognitive-Behavioral Therapy for Adolescents With Autism and Anxiety
Anxiety is very common in autistic youth. Cognitive behavioral therapy (CBT) is the recommended treatment for both autistic and typically-developing (TD) youth with anxiety, yet most families cannot access CBT due to cost…
- Conditions
- Autism Spectrum Disorder, Autism, Anxiety, Anxiety Disorders
- Trial name
- LUNA-A (NCT06537128)
- Testing
- LUNA-Adolescent, Treatment as Usual
- Where
- United States
- Volunteers
- 139 people
- Sponsor
- Baylor College of Medicine
Generalized Anxiety Disorder
Safety, Efficacy and Tolerability of Vilazodone in Generalized Anxiety Disorder
The purpose of this study is to evaluate the efficacy, safety and tolerability of vilazodone relative to placebo in the treatment of generalized anxiety disorder (GAD)
- Trial name
- VLZ-MD-05 (NCT01629966)
- Testing
- Vilazodone
- Where
- 37 sites in United States
- Volunteers
- 680 people
- Sponsor
- Forest Laboratories
Anxiety Disorder/Anxiety State
Online Acceptance and Commitment Therapy for Reducing Anxiety
The main objective of this study is to test the effectiveness of an Internet-delivered Acceptance and Commitment Therapy (ACT) program in reducing anxiety symptoms.
- Trial name
- NCT03074669
- Testing
- ACT program
- Where
- Romania
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- West University of Timisoara
Mental Disorders, Mood Disorders
Group Transdiagnostic Cognitive Behavioural Therapy for Intolerance of Uncertainty Versus Applied Relaxation
Many people find uncertainty distressing, but for some, it may become overwhelming and drive persistent anxiety, worry, and avoidance.
- Conditions
- Mental Disorders, Mood Disorders, Anxiety Disorders, Generalized Anxiety Disorder
- Trial name
- OBSCURA (NCT07866794)
- Testing
- Group Transdiagnostic Cognitive Behavioural Therapy for Intolerance of Uncertainty (CBT-IU), Group Transdiagnostic Applied Relaxation (AR)
- Where
- United Kingdom
- Volunteers
- 135 people
- Sponsor
- Medical Research Council Cognition and Brain Sciences Unit
Panic Disorder, Agoraphobia
Clinical Trial of a Group Self-management Support Program for Anxiety Disorders
Background. Self-management support is a complementary approach to treatment that aims to educate participants on the nature of anxiety and to improve their strategies to manage symptoms and well-being, thus presenting the…
- Conditions
- Panic Disorder, Agoraphobia, Social Anxiety Disorder, Generalized Anxiety Disorder
- Trial name
- NCT05124639
- Testing
- Group self-management support program for anxiety disorders
- Where
- Canada
- Volunteers
- 414 people
- Sponsor
- Université de Sherbrooke
Social Phobia
Improving Treatment Outcomes in Pharmacotherapy of Generalized Social Anxiety Disorder
This study will compare the effectiveness of either adding clonazepam or placebo to standard treatment or switching to venlafaxine in treating generalized social anxiety disorder in individuals who have not responded to treatment…
- Trial name
- NCT00282828
- Testing
- Sertraline, Venlafaxine, Clonazepam
- Where
- 3 sites in United States, Canada
- Volunteers
- 397 people
- Sponsor
- Massachusetts General Hospital