Clinical trials: Anxiety Disorder
Social Anxiety Disorder
Open-label Safety Trial of PH94B in Social Anxiety Disorder (SAD)
This study evaluates the safety and tolerability of PH94B with repeated dosing over a period of up to 12 months. Participating subjects will use PH94B up to 4 times a day when they encounter anxiety-provoking situations in daily…
- Trial name
- NCT05030350
- Testing
- PH94B
- Where
- 3 sites in United States
- Volunteers
- 481 people
- Sponsor
- VistaGen Therapeutics, Inc.
Elective Reconstructive Surgery Population
The Effect of Healing Touch on Sleep
Healing Touch improves measures of sleep the night prior to surgery, thus improving surgery-related morbidity.
- Trial name
- Sleep7 (NCT01870076)
- Testing
- Healing Touch, Control, Presence
- Where
- United States
- Volunteers
- 41 people, healthy volunteers welcome
- Sponsor
- Shriners Hospitals for Children
Social Intelligence
Effect of Intranasal Neuropeptide on Emotion Perception in Trait Anxiety
The purpose of this study is to learn more about how emotional processing may be affected by a hormone called oxytocin. Oxytocin is a hormone that occurs naturally in the body, and may play an important role in the way that the…
- Trial name
- NCT01551303
- Testing
- Oxytocin
- Where
- United States
- Volunteers
- 47 people, healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital
Post-traumatic Stress Disorder, Generalized Anxiety Disorder
Primary Care Intervention Strategy for Anxiety Disorders
This study will compare the effectiveness of an intervention strategy for the treatment of people with post traumatic stress disorder, generalized anxiety disorder, panic disorder, and social anxiety disorder in the primary care…
- Conditions
- Post-traumatic Stress Disorder, Generalized Anxiety Disorder, Panic Disorder, Social Anxiety Disorder
- Trial name
- NCT00347269
- Testing
- Cognitive-behavioral therapy, Psychotropic medication optimization, Treatment as Usual
- Where
- 4 sites in United States
- Volunteers
- 1,004 people
- Sponsor
- University of Washington
Cigarette Smoking
Smoking, Stress, HIV and Mobile Technology
The present investigation aims to address disparities in cigarette use outcomes among Black/African American adults with HIV. The specific aims of this study are: (1) To modify a recently developed, culturally adapted, mobile…
- Trial name
- NCT05709002
- Testing
- MASP+, Control
- Where
- United States
- Volunteers
- 76 people, healthy volunteers welcome
- Sponsor
- University of Houston
Body Dysmorphic Disorder, Obsessive-Compulsive Spectrum Disorder
Cognitive-Behavioral Therapy and Supportive Psychotherapy for Body Dysmorphic Disorder
The purpose of this study is to learn more about two different types of psychotherapy to help individuals who have body dysmorphic disorder (BDD).
- Conditions
- Body Dysmorphic Disorder, Obsessive-Compulsive Spectrum Disorder, Anxiety Disorders, Somatoform Disorders
- Trial name
- NCT01453439
- Testing
- Cognitive Behavioral Therapy, Supportive Psychotherapy
- Where
- 2 sites in United States
- Volunteers
- 120 people
- Sponsor
- Massachusetts General Hospital
Anorexia Nervosa, Eating Disorder
Hormonal Factors in the Treatment of Anorexia Nervosa
The investigators are investigating whether a hormone that is naturally produced by the human body, called testosterone, can help improve weight, disordered eating, depression, and anxiety.
- Conditions
- Anorexia Nervosa, Eating Disorder, Anxiety, Depression
- Trial name
- NCT01121211
- Testing
- Testosterone
- Where
- United States
- Volunteers
- 90 people
- Sponsor
- Massachusetts General Hospital
Arachnophobia, Phobia
TMS and Exposure Therapy
Spider phobia is an exceedingly common phobia throughout the world. The current standard treatment involves exposure therapy, which consists of a series of brief exposures of an individual to the thing they fear, in this case…
- Trial name
- NCT04019054
- Testing
- Intermittent Theta Burst Stimulation (iTBS), Ventromedial Prefrontal Cortex (vmPFC), Intermittent Theta Burst Stimulation (iTBS), vertex
- Where
- United States
- Volunteers
- 22 people
- Sponsor
- University of California, Los Angeles
Mental Health Issue, Alcohol Use Disorder
Acceptability and Feasibility of Cognitive Behavioral Therapy for Treatment-Seeking (CBT-TS) With Deaf Individuals
The current study aims to assess the acceptability and feasibility of an adapted version of Cognitive Behavioral Therapy for Treatment Seeking (CBT-TS) for use with signing Deaf adults.
- Conditions
- Mental Health Issue, Alcohol Use Disorder, Depression, Anxiety
- Trial name
- NCT05520190
- Testing
- Cognitive Behavioral Therapy for Treatment Seeking (CBT-TS)
- Where
- United States
- Volunteers
- 42 people
- Sponsor
- University of Rochester
Multiple Sclerosis
Isokinetic Exercises in Patients With Multiple Sclerosis
The investigators evaluated the effects of isokinetic muscle strengthening exercises of the quadriceps and hamstring on muscle strength, joint position sense, pain, kinesiophobia and quality of life in patients with multiple…
- Trial name
- NCT03779724
- Testing
- exercises
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 50 people
- Sponsor
- Aksaray University Training and Research Hospital
Obsessive-Compulsive Disorder
Randomized Controlled Trial of Intranasal Ketamine vs. Intranasal Midazolam in Individuals With OCD
Obsessive-compulsive disorder (OCD) is a common illness that causes significant distress and impairment. Currently, serotonin reuptake inhibitors (SRIs) are the only medications that are FDA-approved to treat OCD.
- Trial name
- NCT02206776
- Testing
- Intranasal Ketamine, Intranasal Midazolam
- Where
- United States
- Volunteers
- 2 people
- Sponsor
- New York State Psychiatric Institute
Social Anxiety Disorder
Efficacy of BNC210 in Acute, As-needed Treatment of Anxiety in Social Anxiety Disorder - 1
The purpose of the study is to evaluate the effect of a single, acute dose of BNC210 compared to placebo on reducing the severity of anxiety provoked by a behavioral assessment task and measured using the Subjective Units of…
- Trial name
- AFFIRM-1 (NCT06510504)
- Testing
- 225 mg BNC210
- Where
- 21 sites in United States
- Volunteers
- 370 people
- Sponsor
- Bionomics Limited
Depression, Anxiety
Efficacy and Feasibility of a Personalized Treatment for Depression With Co-Occurring Anxiety
This study will examine the feasibility and efficacy of a personalized psychotherapy treatment for people with depression and co-occurring anxiety.
- Trial name
- NCT00930293
- Testing
- Interpersonal Psychotherapy for Depression with Panic and Anxiety Symptoms (IPT-PS), Brief Supportive Psychotherapy (BSP), Citalopram hydrobromide
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- University of Pittsburgh
Obsessive Compulsive Disorder
Duloxetine for the Treatment of Obsessive Compulsive Disorder (OCD)
The purpose of this study is to assess the efficacy of Duloxetine in the treatment of obsessive compulsive disorder.
- Trial name
- FIJ-MC-1003 (NCT00464698)
- Testing
- Duloxetine
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Massachusetts General Hospital
Onychophagia
Use of N-Acetylcysteine (NAC) in Fingernail Biting
To conduct a pilot randomized placebo-controlled feasibility trial of N-acetylcysteine (NAC) in onychophagia, preliminarily assessing the tolerability and effects of this pharmacotherapy on young adults who bite their…
- Trial name
- NCT01993849
- Testing
- N-Acetylcysteine (NAC)
- Where
- United States
- Volunteers
- 23 people
- Sponsor
- Kevin Gray, MD
Stress, Anxiety
Auriculotherapy Effectiveness on Stress and Anxiety in Nursing Student
Single-blind randomized controlled trial aimed to assess stress and anxiety levels in Nursing School students of Beneficence Portuguese Hospital and review the effectiveness of true and placebo auriculotherapy.
- Trial name
- NCT01420848
- Testing
- Auriculotherapy
- Where
- Brazil
- Volunteers
- 71 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo
Hematopoietic and Lymphatic System Neoplasm, Metastatic Malignant Solid Neoplasm
Psilocybin-Assisted Therapy for the Treatment of Cancer-Related Anxiety in Patients With Metastatic Cancer
This phase I/II trial tests the safety and side effects of psilocybin in combination with therapy for the treatment of patients with metastatic cancer and symptoms of anxiety and/or depression.
- Trial name
- NCT05847686
- Testing
- Counseling, Psilocybin, Questionnaire Administration
- Where
- United States
- Volunteers
- 55 people
- Sponsor
- University of Washington
Autism, Asperger's Syndrome
Exposure-Focused Family-Based CBT for Youth With ASD and Comorbid Anxiety
Autism spectrum disorders affect as many as 1 out of 88 children and are related to significant impairment in social, adaptive, and school functioning.
- Conditions
- Autism, Asperger's Syndrome, Pervasive Developmental Disorder Not Otherwise Specified, Generalized Anxiety Disorder
- Trial name
- NCT01919970
- Testing
- Cognitive Behavioral Therapy, Treatment as usual
- Where
- United States
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- University of South Florida
Anxiety
Interpretation Training to Reduce Anxiety: Evaluating Technology-based Delivery Models and Methods to Reduce Attrition
The project aims to compare effectiveness and target engagement of CBM-I delivered via computer vs. mobile phone, and test if adding minimal human contact for participants at risk of dropout improves retention and outcomes.
- Trial name
- NCT03498651
- Testing
- Cognitive Bias Modification - Interpretation training, Coaching, Online psychoeducation about anxiety
- Where
- United States
- Volunteers
- 1,748 people
- Sponsor
- University of Virginia
Abdominal Pain, Anxiety
Anxiety and Recurrent Abdominal Pain in Children
This study aims to determine whether citalopram is a useful, well-tolerated, and safe treatment for children and adolescents ages 7 to 18 years with functional abdominal pain.
- Trial name
- NCT00962039
- Testing
- Citalopram
- Where
- United States
- Volunteers
- 81 people
- Sponsor
- John V. Campo, M.D.