Clinical trials: Anxiety Disorders
Anxiety Disorder
GEM 1.5 mg b.i.d. to 4.5 mg b.i.d. Versus Lorazepam in GAD (0777-026)
This study will determine the effectiveness of MK0777 GEM versus Lorazepam in the treatment of patients with generalized anxiety disorder.
- Trial name
- NCT00546624
- Testing
- MK0777
- Volunteers
- 38 people
- Sponsor
- Merck Sharp & Dohme LLC
Anxiety Disorders
An Eight-Week Study to Evaluate the Efficacy and Safety of SR58611A in Elderly Patients With Generalized Anxiety Disorder
The primary objective of this study is to demonstrate the efficacy of SR58611A 350 mg twice a day compared to placebo in elderly patients with Generalized Anxiety Disorder (GAD), as assessed by the 14-item Hamilton Anxiety rating…
- Trial name
- GEMINI (NCT00535340)
- Testing
- SR58611A
- Where
- 5 sites in Austria, Croatia and 3 more
- Volunteers
- 55 people
- Sponsor
- Sanofi
Dental Anxiety
Trial of Pregabalin, Alprazolam, and Placebo in Subjects With Anxiety Prior to Dental Procedure
The primary purpose of the trial is to assess how effective pregabalin, alprazolam, and placebo are at reducing anxiety levels of subjects who take a dose of these treatments 4 hours before a scheduled dental procedure.
- Trial name
- NCT00245609
- Testing
- Pregabalin, Alprazolam
- Where
- 9 sites in Germany, United Kingdom
- Volunteers
- 90 people
- Sponsor
- Pfizer's Upjohn has merged with Mylan to form Viatris Inc.
Sleep, Pain
Radicle Health1: A Study of Health and Wellness Formulations and Their Effects on Overall Health
A randomized, blinded, placebo-controlled study of health and wellness product formulations and their effects on overall health
- Conditions
- Sleep, Pain, Depression, Anxiety
- Trial name
- NCT05783232
- Testing
- Health Active Study Product 1.1 Capsules, Health Active Study Product 1.2 Capsules, Health Active Study Product 1.3 Capsules
- Where
- United States
- Volunteers
- 1,494 people, healthy volunteers welcome
- Sponsor
- Radicle Science
Obsessive-Compulsive Disorder
Child and Adolescent OCD Outcomes From Exposure and Response Prevention Video Teletherapy Treatment
This is a naturalistic, observational study of children and adolescents with obsessive-compulsive disorder who were treated with exposure and response prevention via video teletherapy.
- Trial name
- NCT06466447
- Testing
- Exposure and response prevention therapy
- Where
- United States
- Volunteers
- 2,173 people
- Sponsor
- NOCD
Perinatal Depression, Specific Phobia
Maternal Telemental Health Interventions in Response to Covid-19*
The purpose of this study is to assess the effectiveness of a telemental health intervention on the mental health of pregnant women during the COVID-19 crisis in Qatar.
- Conditions
- Perinatal Depression, Specific Phobia, Perinatal Anxiety
- Trial name
- CoronaVirus (NCT04594525)
- Testing
- Low-Intensity Psychosocial Interventions through Telemental health
- Where
- Qatar
- Volunteers
- 58 people
- Sponsor
- Hamad Medical Corporation
Severe Crohn's Disease, Anxiety
Reveal the Level of Anxiety in Patients With Crohn's Disease Receiving Adalimumab
It has been shown that emotional health issues, such as state anxiety, are more prevalent in patients suffering from inflammatory bowel disease (IBD) compared to physically healthy subjects.
- Trial name
- RELAX (NCT01428115)
- Where
- 8 sites in Austria
- Volunteers
- 83 people
- Sponsor
- AbbVie (prior sponsor, Abbott)
Schizophrenia, Major Depressive Disorder
PHARMO Institute Seroquel Safety Study
The purpose of this observational study is to study specific outcomes of interest in users of quetiapine compared with all other atypical antipsychotics and specifically olanzapine and risperidone.
- Conditions
- Schizophrenia, Major Depressive Disorder, Bipolar Disorder, Generalized Anxiety Disorder
- Trial name
- PHARMO II (NCT01342120)
- Volunteers
- 18,325 people
- Sponsor
- AstraZeneca
Panic Disorder
Xenon Inhalation for Treatment of Panic Disorder
This study is a double-blind, randomized, placebo-controlled, clinical trial in parallel groups in patients with panic disorder.
- Trial name
- NCT04432155
- Testing
- Xenon
- Volunteers
- 200 people
- Sponsor
- Nobilis Therapeutics Inc.
Quality of Life
Medical Affairs Pharmaceutical Physician Work-related Quality of Life (MAPPWrQoL) Instrument Development and Patient Registry (MAPPWrQoLReg)
Existing evidence has shown that medical affairs pharmaceutical physicians (MAPPs), are a core function within the pharmaceutical industry.
- Trial name
- NCT05123846
- Where
- United Kingdom
- Volunteers
- 180 people
- Sponsor
- Medialis Ltd.
Depressive Symptoms, Anxiety Disorders
Messaging Therapy for Depression and Anxiety: A Longitudinal Effectiveness Study
Therapies delivered via technology have been developed to improve accessibility, however, there is limited research regarding messaging therapy in particular, and none that we know of utilizing a longitudinal effectiveness…
- Trial name
- NCT03699488
- Testing
- psychotherapy via asynchronous message
- Volunteers
- 12,980 people
- Sponsor
- Talkspace
Anxiety Disorders
A Study of MK0777 in the Treatment of Outpatients With Generalized Anxiety Disorder (0777-020)
The study will look at the effect of MK0777on reducing anxiety in subjects with general anxiety disorder. This is an early phase trial and some specific protocol information is in progress and not publicly available at this time.
- Trial name
- NCT00543920
- Testing
- MK0777
- Volunteers
- 60 people
- Sponsor
- Merck Sharp & Dohme LLC
Depression, Anxiety
Integrating a Suite of Mental Health Apps for Depression in a Healthcare Setting
The purpose of this study is to evaluate the implementation of IntelliCare as a frontline intervention within health care settings.
- Trial name
- NCT05274620
- Testing
- IntelliCare
- Where
- 2 sites in United States
- Volunteers
- 82 people
- Sponsor
- Adaptive Health, Inc
Pediatric Acute-Onset Neuropsychiatric Syndrome, Pediatric Autoimmune Neuropsychiatric Disorders Associated With Streptococcal Infections
A Study to Evaluate the Benefit of Octagam 5%® in Subjects With Pediatric Acute-onset Neuropsychiatric Syndrome (PANS)
This study will evaluate the use of intravenous immunoglobulins (IVIG) at a dose of 1g/Kg/body weight given every three weeks for 6 infusions in pediatric subjects ages 4 - 16 years with moderate to severe PANS.
- Trial name
- PANS (NCT03348618)
- Testing
- IVIG
- Where
- 3 sites in United States
- Volunteers
- 21 people
- Sponsor
- IMMUNOe Research Centers
Generalized Anxiety Disorder
A Clinical Study That Will Measure How Well SEP-363856 Works and How Safe it is in Adults With Generalized Anxiety Disorder
A clinical study that will meaure how well SEP-363856 works and how safe it is in adults with Generalized Anixety Disorder. This study will be accepting both male and female subjects between the ages of 18 years and 65 years old.
- Trial name
- NCT05729373
- Testing
- SEP-363856
- Where
- 83 sites in United States, Bulgaria and 6 more
- Volunteers
- 434 people
- Sponsor
- Otsuka Pharmaceutical Development & Commercialization, Inc.
Depression, Anxiety
Meru Health Program to Treat Depression in Primary Care
Meru Health Inc. seeks to further validate the Meru Health Program (MHP) as a single solution to screening, referral, and treatment in primary care as compared to treatment as usual using a Randomized Controlled Trial (RCT) study…
- Trial name
- NCT05615662
- Testing
- Meru Health Program, Treatment as Usual
- Where
- United States
- Sponsor
- Meru Health, Inc.
Anxiety
Correlates of Anxiety Associated With a Life-threatening Illness
The goal of this observational trial is to gather brain scan data on people undergoing MDMA-assisted therapy. The main question it aims to answer is: -How does brain activity change while completing an emotional regulation task…
- Trial name
- NCT02954562
- Testing
- fMRI
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- Resilient Pharmaceuticals
Sleep Disorder (Disorder), Anxiety Depression Disorder
The Effect of Avnace eZZe on Sleep Improvement
This study aims to examine the effectiveness of Avance eZZe drink with liposomal technology in improving sleep quality. Participants will be randomly assigned to either the placebo group, Avance eZZe drink group, and Avance eZZe…
- Trial name
- NCT07172607
- Testing
- Avance eZZe drink, Avance eZZe drink (without liposomal)
- Where
- Taiwan
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- TCI Co., Ltd.
Social Phobia
A Study To Evaluate The Effect Of GW876008 On The Pharmacokinetics Of Oral Contraceptive Pills
This study will be conducted in healthy female volunteers to investigate the effect of GW876008 on the pharmacokinetics of oral contraceptive pills.
- Trial name
- NCT00508911
- Testing
- GW876008, COC
- Where
- United Kingdom
- Volunteers
- 4 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Mild Cognitive Impairment, Anxiety State
Efficacy of Sublingual 5-MeO-DMT for Reducing Anxiety and Depression in MCI
This Phase I/II clinical trial aims to test the effectiveness of a new sublingual formulation of 5-MeO-DMT in reducing symptoms of anxiety, depression, and cognitive decline in individuals with mild to moderate Alzheimer's…
- Conditions
- Mild Cognitive Impairment, Anxiety State, Depression Anxiety Disorder
- Trial name
- 5-MeO-DMT (NCT06812221)
- Testing
- Sublingual administration, Electroencephalography, Biochemical mesurements
- Where
- Argentina
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Biomind Labs Inc.