Clinical trials: Anxiety Disorders
Anxiety
Sublingual Cannabidiol for Anxiety
This is an open-label to double-blind study evaluating the effects of cannabidiol (CBD) for the treatment of anxiety in adults. Participants will use a sublingual (under-the-tongue) solution of whole plant-derived CBD or placebo…
- Trial name
- NCT02548559
- Testing
- Full-Spectrum Cannabidiol, Single-Compound Cannabidiol
- Where
- United States
- Volunteers
- 46 people
- Sponsor
- Staci Gruber, Ph.D.
Social Anxiety Disorder, Selective Mutism
Treatment of Social Anxiety Disorder and Selective Mutism
This study is to assess the efficacy of a brief, 11-week, manualized Taming Sneaky Fears for Social Anxiety Disorder (SAD) and/or Selective Mutism (SM) child and parent group Cognitive Behavioural Therapy (CBT) treatment…
- Trial name
- SAD&SMTRMT (NCT02554929)
- Testing
- Taming Sneaky Fears, Parent Psycho-education and Child Socialization
- Where
- Canada
- Volunteers
- 93 people
- Sponsor
- The Hospital for Sick Children
Neurotic Excoriation, Pathologic Skin Picking
Double-Blind Lamictal (Lamotrigine) in Neurotic Excoriation
The goal of the proposed study is to evaluate the comparative efficacy of Lamictal (lamotrigine) to placebo in neurotic excoriation.
- Conditions
- Neurotic Excoriation, Pathologic Skin Picking, Psychogenic Excoriation, Dermatillomania
- Trial name
- NCT00513019
- Testing
- Lamictal (lamotrigine)
- Where
- United States
- Volunteers
- 35 people
- Sponsor
- University of Chicago
Epilepsy, Anxiety
Use of Clobazam for Epilepsy and Anxiety
This study is an open label, adjunctive, proof of concept, pilot clinical trial. Pediatric patients with epilepsy and clinically significant anxiety will be recruited and if enrolled will receive active treatment, involving…
- Trial name
- NCT03371836
- Testing
- Clobazam
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Hugo W. Moser Research Institute at Kennedy Krieger, Inc.
Anxiety, Laceration Repair
iPad as a Distraction Tool During Facial Laceration Repair
Children aged 2-12 presenting to the Rady Children's Hospital San Diego (RCHSD) emergency department with facial lacerations requiring suture repair will be eligible to participate in the study.
- Conditions
- Anxiety, Laceration Repair, Children
- Trial name
- NCT02217436
- Testing
- iPad, Standard Care
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- University of California, San Diego
Anxiety
Calmer Life: Treating Worry Among Older Adults In Underserved, Low-income, Minority Communities
The purpose of this research study is to see how helpful two different interventions offered through the Calmer Life program are in reducing worry and improving mood.
- Trial name
- NCT02391363
- Testing
- Cognitive behavior treatment, Information and referral
- Where
- United States
- Volunteers
- 247 people
- Sponsor
- Baylor College of Medicine
Alcohol Dependence
Treatment Strategy for Alcohol Use Disorders in Veterans With TBI
The purpose of this research study is to understand the effectiveness of valproate (a common mood stabilizer) to further reduce alcohol misuse when given in addition to attending an alcohol rehabilitation program as well as the…
- Trial name
- AUD (NCT01342549)
- Testing
- Valproate, Naltrexone
- Where
- 2 sites in United States
- Volunteers
- 62 people
- Sponsor
- VA Office of Research and Development
Cancer
Psilocybin Cancer Anxiety Study
The primary objective of this double-blind, placebo-controlled pilot study is to assess the efficacy of psilocybin administration (4-phosphoryloxy-N,N-dimethyltryptamine), a serotonergic psychoactive agent, on psychosocial…
- Trial name
- NCT00957359
- Testing
- Psilocybin, Niacin
- Where
- United States
- Volunteers
- 29 people
- Sponsor
- NYU Langone Health
Obsessive-compulsive Disorder
D-Cycloserine Augmentation of Therapy for Pediatric Obsessive-Compulsive Disorder
Cognitive-behavioral therapy (CBT) has proven efficacy for treatment of pediatric obsessive-compulsive disorder (OCD). Yet, CBT does not help all children and those who benefit often remain symptomatic upon treatment completion.
- Trial name
- NCT00864123
- Testing
- Cognitive-behavioral therapy, D-cycloserine
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of South Florida
Panic Disorder
Special Investigation Of J Zoloft For Panic Disorder Patients
The objective of this surveillance is to collect information for panic disorder patients about 1) adverse drug reactions not expected from the LPD (unknown adverse drug reactions), 2) the incidence of adverse drug reactions in…
- Trial name
- NCT00605917
- Testing
- Sertraline hydrochloride
- Volunteers
- 997 people
- Sponsor
- Pfizer's Upjohn has merged with Mylan to form Viatris Inc.
Anxiety
Reducing Anxiety and Stress in Primary Care Patients
Anxiety is common among primary care patients, but is undertreated. The purpose of this study is to evaluate whether a brief anxiety treatment designed for VA primary care is more effective at reducing anxiety symptoms in…
- Trial name
- NCT03794089
- Testing
- Brief anxiety intervention, Usual PC-MHI care
- Where
- United States
- Volunteers
- 35 people
- Sponsor
- VA Office of Research and Development
Anxiety, Depression
Improving Adherence to Homework During Therapy
The purpose of this study is to expand Adhere.ly- a simple, HIPAA-compliant, web-based platform to help therapists engage clients in practicing therapeutic skills between sessions (homework) during mental health treatment by…
- Conditions
- Anxiety, Depression, Depression/Anxiety
- Trial name
- Adherely STTR (NCT05866185)
- Testing
- Therapy, Therapy + Adhere.ly
- Where
- United States
- Volunteers
- 79 people
- Sponsor
- University of South Florida
Parkinson's Disease, Depression
Barriers to Mental Healthcare Utilization in Parkinson's Disease
Parkinson's disease (PD) is the second most common neurodegenerative disorder in the elderly. In most people, the illness is complicated by co-occurring psychiatric problems such as depression and anxiety.
- Conditions
- Parkinson's Disease, Depression, Anxiety
- Trial name
- NCT01167608
- Testing
- No Intervention. This is a cross-sectional survey study.
- Where
- United States
- Volunteers
- 883 people, healthy volunteers welcome
- Sponsor
- Rutgers, The State University of New Jersey
ANXIETY DISORDERS (or Anxiety and Phobic Neuroses)
Fast-Fail Trials in Mood and Anxiety Spectrum Disorders; Kappa Opioid Receptor Phase 2a
The available treatment for patients with mood and anxiety disorders have significant limitations (Rush, 2007; Denys and de Geus, 2005). There is a need to develop new treatments for people with these disorders.
- Trial name
- FASTMAS_Kor2 (NCT02218736)
- Testing
- CERC-501
- Where
- 6 sites in United States
- Volunteers
- 163 people
- Sponsor
- Duke University
First Trimester Abortion, Virtual Reality
Virtual Reality Experience in First Trimester D&C
Virtual reality (VR) has been used in health care settings to decrease anxiety and pain. This project is a feasibility study to evaluate whether virtual reality can be used in the setting of a first trimester pregnancy…
- Trial name
- NCT03533036
- Testing
- applied VR headset
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of California, Los Angeles
Patient Diagnosed With OCD and Resistant to SSRI Treatment, Failed SSRI Over 12 Weeks at Appropriate Doses
Study to Evaluate the Effect of AFQ056 in Obsessive Compulsive Disorder (OCD) Patients Resistant to Selective Serotonin Reuptake Inhibitor (SSRI) Therapy
The purpose of this study is to determine whether AFQ056 as an add on therapy to SSRIs can have beneficial effects by reducing the total score of Y-BOCS (Yale and Brown Obsessive Compulsive Scale) in OCD patients resistant to…
- Trial name
- NCT01813019
- Testing
- AFQ056
- Where
- 15 sites in United States, Bulgaria and 3 more
- Volunteers
- 50 people
- Sponsor
- Novartis Pharmaceuticals
Panic Disorder
Safety and Efficacy of HB-1 for Panic Disorder
The purpose of this study is to determine the safety and efficacy of potential new treatment called "HB-1" versus placebo in male and female adult patients aged 18 to 60 years, inclusive, with panic disorder.
- Trial name
- NCT05071430
- Testing
- HB-01
- Where
- 10 sites in United States
- Volunteers
- 86 people
- Sponsor
- HB BioTech, LLC
Anxiety, Pain
Relaxing Environment to Lower Anxiety During Onabotulinum Toxin Chemodenervation of the Bladder
Chemodenervation of the bladder with onabotulinum toxin A is an effective treatment option for patients with refractory urgency urinary incontinence (UUI).
- Conditions
- Anxiety, Pain, Burnout, Professional
- Trial name
- RELAX (NCT06319898)
- Testing
- Lavender aromatherapy sticker
- Where
- United States
- Volunteers
- 113 people
- Sponsor
- Wake Forest University Health Sciences
Anxiety
Sleep and Emotional Memory in Peripubertal Anxiety
The current study aims to deepen understanding of the symptom dimension of negative overgeneralization in anxiety. Specifically, the study examines the malleability of memory processes that are known to occur during sleep that…
- Trial name
- NCT03643848
- Testing
- Sleep with Sound Cues
- Where
- 2 sites in United States
- Volunteers
- 58 people, healthy volunteers welcome
- Sponsor
- Florida International University
Anxiety
Lysergic Acid Diethylamide (LSD)-Assisted Psychotherapy in People With Illness-related Anxiety
This study will find out whether psychotherapy combined with lysergic acid diethylamide (LSD) is safe and is helpful in people who are anxious because they have a potentially fatal disease.
- Trial name
- NCT00920387
- Testing
- 200 mcg LSD, 20 mcg LSD, Therapy
- Where
- Switzerland
- Volunteers
- 12 people
- Sponsor
- Multidisciplinary Association for Psychedelic Studies