Clinical trials: Anxiety and Fear-Related Disorders
Panic Disorder, Phobic Disorders
Threat-Avoidance Learning in Anxiety Patients
Anxiety disorders are characterized by exaggerated levels of fear that are not proportional to the actual level of threat. More specifically, anxiety patients have marked deficits in the downregulation of fear reactions during…
- Conditions
- Panic Disorder, Phobic Disorders, Stress Disorders, Traumatic
- Trial name
- AVOID (NCT02336802)
- Testing
- Avoidance experiment
- Where
- Belgium
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- KU Leuven
Fear, PTSD
Investigations of Amygdala Function Using Neurophysiological Recording and Stimulation
This study aims to specifically examine the in vivo electrophysiology and effects of direct stimulation of the human amygdala during conditioned and evoked fear.
- Conditions
- Fear, PTSD, Panic Disorder
- Trial name
- NCT03958903
- Testing
- Amygdala recording and stimulation using Neuropace RNS, Behavioral tasks
- Where
- United States
- Volunteers
- 23 people
- Sponsor
- Stanford University
Pain, Fear
Virtual-Reality and Cold-Vibration Device on Procedure-Related Fear, Anxiety and Pain During Pediatric IV Line Placement
Studies evaluating VR are quite insufficient. In the study we determined in the emergency room between the ages of 4-10, cold vibration and virtual reality will be compared, and the success of the first attempt, pain, fear and…
- Conditions
- Pain, Fear, Anxiety, Child, Only
- Trial name
- IVVRBuzzy (NCT04853056)
- Testing
- virtual reality, Cold vibration
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people
- Sponsor
- Dokuz Eylul University
Posttraumatic Stress Disorder (PTSD), Specific Phobia
Intervention for Anxiety After Falls
The purpose of this study is to determine whether a brief intervention for disabling anxiety is practical to conduct and beneficial for older adults injured by falls.
- Conditions
- Posttraumatic Stress Disorder (PTSD), Specific Phobia, Anxiety
- Trial name
- NCT01268657
- Testing
- Education, Relaxation Training, Cognitive Restructuring
- Where
- United States
- Volunteers
- 23 people
- Sponsor
- Weill Medical College of Cornell University
Ankle Sprains
Fear of Movement, Functionality and Quality of Life in Elite Athletes With an Ankle Instability History
Ankle sprain is frequently experienced by individuals participating in different sports activities. Ankle sprains have been shown to result in a decrease in level of physical activity and persistence of some symptoms for a long…
- Trial name
- NCT04789369
- Testing
- Questionnaires
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people
- Sponsor
- Acibadem University
Periodontitis
Effect of Periodontitis Treatment on Quality of Life and Experiences of Fear, Anxiety and Pain
There are different protocols to treat gum diseases. One relevant differential aspect is related to time. There are protocols that usually takes one to two months to be completed while other are completed within 24 hours.
- Trial name
- NCT02409966
- Testing
- Quadrant-wise scaling, Full-mouth 24-hour scaling
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- University of Taubate
Menstrual Irregularity, Stress Related Disorder
Women's Menstruation During the Covid-19 Pandemic
The COVID-19 crisis has rapidly become the most significant public health crisis of our times. It has particularly impacted healthcare workers (HCW) due to the over-whelming of healthcare resources, as well as a critical absence…
- Conditions
- Menstrual Irregularity, Stress Related Disorder, COVID-19 Pneumonia, Fear
- Trial name
- NCT05197491
- Where
- Egypt
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Fayoum University
Posttraumatic Stress Disorder, Subsyndromal Posttraumatic Stress Disorder
Back on My Feet: Emotional Recovery From Fall Injury
We will compare two programs that are designed to help older adults who have had fall injuries manage anxiety and improve their level of functioning.
- Conditions
- Posttraumatic Stress Disorder, Subsyndromal Posttraumatic Stress Disorder, Fear of Falling
- Trial name
- NCT01998945
- Testing
- Exposure-based Cognitive Behavioral Therapy, Relaxation Training
- Where
- United States
- Volunteers
- 22 people
- Sponsor
- Weill Medical College of Cornell University
Chronic Neck Pain
Pain, Fear of Movement, Neck Awareness and Upper Extremity Functionality in Chronic Neck Pain
Our study aims to investigate the parameters related to pain catastrophizing, fear of movement, neck awareness and upper extremity functionality in individuals with chronic neck pain - a cross-sectional study.
- Trial name
- NCT07247214
- Where
- Turkey (Türkiye)
- Volunteers
- 114 people, healthy volunteers welcome
- Sponsor
- Hasan Kalyoncu University
Arthritis, Juvenile, Arthritis, Juvenile Idiopathic
Hypnotherapy for Needle-related Procedural Pain and Anxiety Management in a Pediatric Setting
The proposed study aims to evaluate the effectiveness of hypnotherapy as a non-pharmacological intervention for managing pain and anxiety during needle-related medical procedures in children aged 5 to 17 years.
- Conditions
- Arthritis, Juvenile, Arthritis, Juvenile Idiopathic, Lupus Erythematosus, Systemic, Dermatomyositis, Juvenile
- Trial name
- NCT07349667
- Testing
- Hypnotherapy
- Where
- Denmark
- Volunteers
- 70 people
- Sponsor
- Aarhus University Hospital
Low Back Pain
The Effect of Graded Activity and Pain Education (GAPE) for Patients Early After Lumbar Spinal Fusion
Background An increasing number of patients with chronic low back pain (CLBP) undergo lumbar spinal fusion (LSF). Unfortunately, a substantial part of the patients still has persistent pain, functional disability and poor quality…
- Trial name
- NCT04103970
- Testing
- Graded Activity and Pain Education (GAPE)
- Where
- Denmark
- Volunteers
- 144 people
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Chronic Neck Pain
Kinesiophobia, Pain and Disability in Chronic Neck Pain
This study aims to investigate the mediating role of kinesiophobia in the relationship between pain intensity and disability in individuals with chronic neck pain.
- Trial name
- NCT07525557
- Where
- Turkey (Türkiye)
- Volunteers
- 250 people
- Sponsor
- Ondokuz Mayıs University
PTSD
Effects of Methylphenidate (Ritalin®) on the Neural Basis of Anxiety
In the present study, investigator will investigate the effects of methylphenidate (40 mg) on mPFC activity in healthy male volunteers during fear extinction using functional magnetic resonance imaging (fMRI).
- Trial name
- NCT02021214
- Testing
- Methylphenidate
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- University of California, San Diego
Fear of Childbirth, Anxiety Disorders
"Educational Intervention for Tokophobia in Pregnant Women"
This quasi-experimental study aims to evaluate the effectiveness of structured educational sessions on tokophobia among pregnant women.
- Conditions
- Fear of Childbirth, Anxiety Disorders, Pregnancy-Related Anxiety
- Trial name
- TOKO-EDU (NCT07522814)
- Testing
- Educational Sessions on Tokophobia
- Where
- Egypt
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Delta University for Science and Technology
Post Traumatic Stress Disorder, Anxiety Disorders
Neuroimaging of Pavlovian Fear Conditioning Processes in Patients With Pathological Anxiety
The purpose of this study is to use functional magnetic resonance imaging to investigate how the human brain learns to form associations between neutral and emotional stimuli.
- Conditions
- Post Traumatic Stress Disorder, Anxiety Disorders, Panic Disorder, Social Phobia
- Trial name
- NCT03498599
- Testing
- Novelty facilitated extinction, Standard Extinction
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- University of Texas at Austin
Post-Traumatic Stress Disorders, Stress Disorders
Psychotherapy Treatment of Deployment-Related PTSD in Primary Care Settings
The purpose of this study is to evaluate Cognitive-behavioral therapy (CBT) for deployment-related post-traumatic stress disorder (PTSD) that can be used by behavioral health consultants working with Service Members in the…
- Conditions
- Post-Traumatic Stress Disorders, Stress Disorders, Combat Disorders
- Trial name
- NCT00974402
- Testing
- Cognitive Behavioral Therapy
- Where
- 3 sites in United States
- Volunteers
- 35 people
- Sponsor
- The University of Texas Health Science Center at San Antonio
Childbirth Fear, Anxiety,Birth Pain
Anxieties Related to Childbirth and Postpartum Period
The present study aimed to evaluate the relation of labor pain with anxiety and worries about labor and postpartum period in pregnant women in their last trimester.
- Trial name
- Anxietybirth (NCT04478604)
- Testing
- applied forms to pregnant women
- Where
- Turkey (Türkiye)
- Volunteers
- 104 people, healthy volunteers welcome
- Sponsor
- Saglik Bilimleri Universitesi Gulhane Tip Fakultesi
Kinesiophobia (Fear of Movement), Experimental Pain
Pain Beliefs and Intracortical Excitability During Experimental Pain
Pain can influence the way the motor system functions. However, responses to pain vary widely between individuals, and this variability may be partly related to pain-related beliefs such as kinesiophobia.
- Trial name
- NCT07688525
- Testing
- Topical Capsaicin Cream (1%)
- Where
- Canada
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Université de Sherbrooke
Exercise Training, Photobiomodulation Therapy
Effects of Different Exercise Programs Plus Photobiomodulation on Non-specific Low-back Pain.
The present project aims to examine the effects of different exercise programs (Pilates and multicomponent) combined with photobiomodulation therapy (PBMT) on pain intensity, postural balance, perceived disability, kinesiophobia…
- Conditions
- Exercise Training, Photobiomodulation Therapy, Low Back Pain
- Trial name
- NCT04887987
- Testing
- Pilates training + active PBMT, Multicomponent training + active PBMT
- Where
- Brazil
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Universidade Norte do Paraná
Ureteroscopy
Effects of Virtual Reality and Stress Ball on Fear, Pain, Anxiety, and Satisfaction in Ureterorenoscopy Patients
This study aimed to determine the effects of virtual reality and stress ball interventions on procedure-related fear, anxiety, and patient satisfaction in patients undergoing ureterorenoscopy.
- Trial name
- NCT07265960
- Testing
- Virtual Reality, Stress Ball
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Tarsus University