Clinical trials: Anxiety and Mood Disorders
Obsessions, Suicide
Obsessions and Suicidality in Youth With Bipolar 1 Disorder
Obsessive-compulsive disorder (OCD) is a common co-morbidity with bipolar I disorder, a comorbidity that is known to increase suicide risk.
- Conditions
- Obsessions, Suicide, Bipolar I Disorder, Obsessive-Compulsive Disorder
- Trial name
- NCT05878808
- Testing
- Psychometric assessment
- Where
- Egypt
- Volunteers
- 80 people
- Sponsor
- Cairo University
Depressive Disorder, Schizophrenia
Magnetic Seizure Therapy (MST) for Treatment Resistant Depression, Schizophrenia, and Obsessive Compulsive Disorder
Electroconvulsive therapy (ECT) has unparalleled efficacy in treating severe depression, and is also useful in treatment-refractory cases of schizophrenia and obsessive compulsive disorder (OCD).
- Conditions
- Depressive Disorder, Schizophrenia, Schizoaffective Disorder, Obsessive-Compulsive Disorder
- Trial name
- NCT01596608
- Testing
- Magnetic Seizure Therapy (MagPro MST)
- Where
- Canada
- Volunteers
- 224 people
- Sponsor
- Centre for Addiction and Mental Health
Spinal Cord Injuries (SCI), Chronic Pain
Virtual Reality-Based Hypnotherapy for Pain, Sleep, and Mood in Spinal Cord Injury
The goal of this clinical trial is to learn whether virtual reality (VR)-based hypnotherapy, added to conventional physiotherapy, improves pain, sleep, mood, and quality of life in adults with chronic spinal cord injury.
- Conditions
- Spinal Cord Injuries (SCI), Chronic Pain, Neuropathic Pain, Sleep Disturbance
- Trial name
- HypnoVR-SCI (NCT07846410)
- Testing
- Virtual Reality-Based Hypnotherapy, Conventional Physiotherapy
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people
- Sponsor
- Istanbul Physical Medicine Rehabilitation Training and Research Hospital
Depression, Anxiety
Clinical and Cost Effectiveness of Brief Cognitive-Behavioral Therapy (CBT) for Pediatric Internalizing Disorders
This project assesses the clinical and cost effectiveness of brief cognitive-behavioral therapy (CBT) for depressed (ages 11-17) and anxious (ages 8-17) youths seen for services in pediatric primary care.
- Trial name
- NCT00669526
- Testing
- BCBT, SMHC referral
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Robert Wood Johnson Foundation
Well-Being, Psychological, Mood
Mushrooms, Mood and Mental Wellbeing in Gen Z Women
The aim of the study is to investigate the effects of 28 days supplementation of Lions mane mushroom and mushroom blend of Lions mane and reishi mushroom, on wellbeing in stressed or anxious women.
- Conditions
- Well-Being, Psychological, Mood, Anxiety, Stress
- Trial name
- NCT06406946
- Testing
- Lion's mane blend, Lion's mane and reishi blend
- Where
- United Kingdom
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- Northumbria University
Depressive Disorder and Anxiety Disorders
To Investigate Effects GSK561679 on Part of the Body's System That Controls the Balance of Many of the Hormones.
A study to investigate the effects GSK561679 on part of the body's system that controls the balance of many of the hormones (including cortisol).
- Trial name
- NCT00426608
- Testing
- metyrapone, alprazolam, GSK561679
- Where
- United Kingdom
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Postpartum Depression, Anxiety
Telephone Coaching Intervention for Postpartum Depression and Anxiety
Mental health problems affect up to 20% of women at some point during the perinatal period (i.e., from pregnancy to one year postpartum.
- Trial name
- NCT04073043
- Testing
- Telephone Coaching
- Where
- Canada
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- McGill University
Anxiety Disorder, Mood Disorder
New Drugs in the Treatment of Mood Disorders
This clinical study compares the effectiveness of two anticonvulsants Lamotrigine (Lamictal) Monotherapy and Gabapentin (Neurontin) in patients with treatment resistant affective disorders.
- Conditions
- Anxiety Disorder, Mood Disorder, Psychotic Disorder
- Trial name
- NCT00001482
- Testing
- Lamotrigine (Lamictal® (Registered Trademark), Gabapentin (Neurontin® (Registered Trademark))
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- National Institute of Mental Health (NIMH)
Anxiety, Anxiety Disorders
Transdiagnostic, Cognitive and Behavioral Intervention for in School-aged Children With Emotional and Behavioral Disturbances
Background Impairing emotional and behavioural problems are common in children and adolescents and mark a three-fold increased risk of mental disorder in young adulthood.
- Conditions
- Anxiety, Anxiety Disorders, Depressive Symptoms, Depressive Disorders
- Trial name
- MindMyMind RCT (NCT03535805)
- Testing
- Mind My Mind (MMM), Treatment as Usual (TAU)
- Where
- Denmark
- Volunteers
- 396 people
- Sponsor
- Mental Health Centre Copenhagen, Bispebjerg and Frederiksberg Hospital
Depression, Anxiety
Symptom-specific TMS Targets for Depression and Anxiety
This pilot study aims to compare two different treatment targets for transcranial magnetic stimulation, an FDA-approved treatment for major depressive disorder (MDD), in terms of their relative efficacy for depression versus…
- Conditions
- Depression, Anxiety, Major Depressive Disorder
- Trial name
- NCT04604210
- Testing
- Transcranial magnetic stimulation
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Brigham and Women's Hospital
Traumatic Brain Injury, Fatigue
Treatment of Post-Traumatic Brain Injury (Post-TBI) Fatigue With Light Therapy
This study aims to evaluate the efficacy of 4 weeks of daily light exposure in reducing Post-Traumatic Brain Injury (TBI) Fatigue immediately post-treatment and at a one-month follow up.
- Trial name
- NCT01725750
- Testing
- Bright White Light (BWL), Dim Red Light (DRL)
- Where
- United States
- Volunteers
- 88 people
- Sponsor
- Icahn School of Medicine at Mount Sinai
Anxiety Disorders, Depressive Disorder
Testing Psychosocial Treatment Planning Methods for Youth Anxiety and Depression
Youth depression and anxiety represent a serious public health concern, with affected youth often experiencing social, familial, and academic impairment.
- Trial name
- NCT03610373
- Testing
- Modular Approach to Therapy for Children (MATCH)
- Where
- United States
- Volunteers
- 45 people
- Sponsor
- Boston University Charles River Campus
Mental Health Screening Adherence
Evaluating Screening Adherence Between Moment for Parents App and Attention Control
Mental health challenges, such as depression and anxiety, are the most common medical complications during pregnancy and after childbirth. Many women experience these symptoms, yet half are never screened, let alone diagnosed.
- Trial name
- NCT07322042
- Testing
- Perinatal Psychoeducation Articles, Bi-weekly Perinatal Mental Health Screening, Chatbot-Guided Journaling
- Where
- United States
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- Poisera, Inc.
Gynecologic Cancers, Surgical Wound Closure Techniques
Effect of Skin Closure Techniques on Body Image in Women Undergoing Gynecologic Surgery
This randomized clinical trial investigates the impact of two different skin closure techniques on body image and mood in women undergoing surgery for gynecologic cancers.
- Conditions
- Gynecologic Cancers, Surgical Wound Closure Techniques, Body Image
- Trial name
- BISGO (NCT07327125)
- Testing
- Continuous Subcuticular Suture, Interrupted Skin Closure
- Where
- Turkey (Türkiye)
- Volunteers
- 140 people
- Sponsor
- Başakşehir Çam & Sakura City Hospital