Clinical trials: Anxiety in Children
Neurodevelopmental Disorders, Autism
Sertraline vs. Placebo in the Treatment of Anxiety in Children and AdoLescents With NeurodevelopMental Disorders
There are currently no approved medications for the treatment of anxiety in children and youth with neurodevelopmental disorders (NDDs), both common and rare.
- Conditions
- Neurodevelopmental Disorders, Autism, Autism Spectrum Disorder, Fragile X Syndrome
- Trial name
- CALM (NCT06081348)
- Testing
- Sertraline
- Where
- 7 sites in Canada
- Volunteers
- 130 people
- Sponsor
- Holland Bloorview Kids Rehabilitation Hospital
Parental Anxiety Following Premature Birth
Impact of Preterm Birth on Symptoms of Anxiety and Depression in Parents, and on the Precursors of Cognition, Including Social Cognition in Their Child
In 2018, the World Health Organization (WHO) counted no less than 15 million preterm births each year worldwide, or more than one in ten children.
- Trial name
- PréDANPa (NCT05734768)
- Testing
- State-Trait Anxiety Inventory - Y ou STAI-Y
- Where
- France
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- CHU de Reims
Pain, Anxiety
Leveraging on Immersive Virtual Reality to Reduce Pain and Anxiety in Children During Immunization in Primary Care
Paediatric immunization is often associated with significant fear and anxiety among children and their parents. Their distress can greatly affect their future adherence to the immunization schedule and the acceptance of…
- Trial name
- NCT04748367
- Testing
- Virtual Reality Headset
- Where
- Singapore
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- SingHealth Polyclinics
Anxiety, Fear
AI Avatar Video vs. Tell-Show-Do for Reducing Anxiety and Improving Cooperation in Children During Local Anesthesia
This randomized clinical trial aims to compare two behavior guidance techniques used to reduce anxiety in children during local anesthesia injections in dental treatment.
- Conditions
- Anxiety, Fear, Local Anesthesia, Pediatric Dentistry
- Trial name
- NCT07449884
- Testing
- AI Avatar-Based video, Tell-Show-Do Technique
- Where
- Lebanon
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Saint-Joseph University
Pain, Acute, Anxiety and Fear
EFFECT OF DISTRACTION METHODS ON PAIN AND ANXIETY DURING INTRAMUSCULAR INJECTION IN CHILDREN
This thesis study was conducted in an unblinded, randomized controlled experimental manner in order to analyze the effect of attention-drawing methods that can be used during intramuscular injection in children on pain and…
- Trial name
- NCT06011668
- Testing
- video game playing, kaleidoscope and virtual reality glasses
- Where
- Turkey (Türkiye)
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- Mersin University
ASD, Anxiety
Administering a Parent-based Pilot Intervention for Reducing Anxiety in Children With ASD and Anxiety
We are implementing the SPACE program, an evidence-based protocol that has been proven to be efficent in childhood anxiety disorders and OCD (Lebowitz, 2013; Lebowitz, Omer, Hermes \& Scahill, 2014), in a new population of…
- Trial name
- NCT04747262
- Testing
- SPACE
- Where
- Israel
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Hebrew University of Jerusalem
Anxiety, Angiocardiography
Virtual Reality-Based Breathing Exercise Before Angiography in Children
hildren undergoing angiography frequently experience anxiety before the procedure, which may negatively affect physiological parameters and procedural cooperation.
- Trial name
- NCT07830420
- Testing
- Virtual Reality-Based Guided Breathing Exercise
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Gazi University
Molar Incisor Hypomineralization
Salivary Cortisol Levels in Children With Molar Incisor Hypomineralization
Molar incisor hypomineralization (MIH) is a developmental condition that affects the enamel of permanent molars and incisors in children and may cause tooth sensitivity, discomfort, and difficulties during dental treatment.
- Trial name
- NCT07389148
- Where
- Turkey (Türkiye)
- Volunteers
- 91 people, healthy volunteers welcome
- Sponsor
- Lokman Hekim University
Autism, Autism Spectrum Disorder
Neural Mechanisms of CBT for Anxiety in Autism (Open Pilot Study)
This is an open, pilot study of neural mechanisms of cognitive-behavioral therapy for anxiety in children with high-functioning autism spectrum disorder (ASD).
- Conditions
- Autism, Autism Spectrum Disorder, Anxiety
- Trial name
- NCT02225808
- Testing
- CBT for anxiety in autism
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Yale University
Fear Anxiety, Satisfaction
The Effect of Reading Fairy Tales and Coloring on Children's Fear Level in Children Who Are Administered Inhaler Medication With a Mask.
This thesis study was conducted as an unblinded, randomized controlled experiment to examine the effects of reading and coloring fairy tales, which can be used during inhaler medication administration with a mask, on children's…
- Trial name
- NCT06486389
- Testing
- reading fairy tales, painting
- Where
- Turkey (Türkiye)
- Volunteers
- 99 people
- Sponsor
- Trakya University
Cerebral Palsy
Analgesia and Physiotherapy in Children With Cerebral Palsy (ANTALKINECP)
SPARCLE 1 and 2 studies followed a cohort of 818 children with cerebral palsy (CP) between 8 and 12 (SPARCLE 1) and 13 and 18 years old (SPARCLE 2) interviewed at home.
- Trial name
- ANTALKINECP (NCT02839785)
- Testing
- Ibuprofen
- Where
- 3 sites in France
- Volunteers
- 3 people
- Sponsor
- University Hospital, Brest
Anxiety, Anxiety Disorders
Transdiagnostic, Cognitive and Behavioral Intervention for in School-aged Children With Emotional and Behavioral Disturbances
Background Impairing emotional and behavioural problems are common in children and adolescents and mark a three-fold increased risk of mental disorder in young adulthood.
- Conditions
- Anxiety, Anxiety Disorders, Depressive Symptoms, Depressive Disorders
- Trial name
- MindMyMind RCT (NCT03535805)
- Testing
- Mind My Mind (MMM), Treatment as Usual (TAU)
- Where
- Denmark
- Volunteers
- 396 people
- Sponsor
- Mental Health Centre Copenhagen, Bispebjerg and Frederiksberg Hospital
Autism, Autism Spectrum Disorder
The Supplementation Therapy in Autism and Response to Treatment Study
In addition to the "core" symptoms of ASD (i.e., impaired communication, impaired reciprocal social interaction and restricted, repetitive and stereotyped patterns of behaviors or interests), it is estimated that up to 70% of…
- Conditions
- Autism, Autism Spectrum Disorder, Autism Spectrum Disorder High-Functioning, Asperger Syndrome
- Trial name
- START (NCT06187090)
- Testing
- Oral Ultramicronized-Palmitoylethanolamide (um-PEA; 600 mg per day) in tablet form
- Where
- Italy
- Volunteers
- 20 people
- Sponsor
- University of Udine
Children, Only, Fear Anxiety
The Effect of Toy-Type Nebulizer on Fear and Anxiety in Children Receiving Inhaler Treatment
The aim of this study is to determine the effect of toy-type nebulizers on fear and anxiety in children receiving inhaler therapy.
- Conditions
- Children, Only, Fear Anxiety, Hospitalism in Children
- Trial name
- NCT05213013
- Testing
- inhaler treatment with the toy-type nebulizer and training on on the use of a nebulizer/mask
- Where
- Turkey (Türkiye)
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- Aylin Kurt
Autism Spectrum Disorder, Anxiety Disorders
DINO RCT - Treating Anxiety in Children With Autism
Anxiety is prevalent in young children, under 7 years of age, with autism. Yet, few studies have examined anxiety interventions for this age range, and only one anxiety treatment study has included young children with cognitive…
- Trial name
- NCT06066983
- Testing
- DINOSAUR, Psychoeducation
- Where
- United States
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Hugo W. Moser Research Institute at Kennedy Krieger, Inc.
Behavior, Child
Effect of Cartoon-assisted Visual/Auditory Distraction Method in Paediatric Dental Patients
The hypothesis of this study was to reveal the positive effects of the visual/auditory distraction usage on anxiety, pain and behavioural control in paediatric patients.
- Trial name
- NCT04927754
- Testing
- Behavioral guidance, Pain assessment, Dental anxiety assessment
- Where
- Turkey (Türkiye)
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Istanbul Medipol University Hospital
Anxiety, Fear
The Effect of Therapeutic Play Before Dressing on Anxiety and Fear in Children
The goal of this experimental study is to determine the effect of therapeutic play method applied to hospitalized children aged 7-12 before the first surgical dressing attempt, on anxiety and fear.
- Trial name
- NCT05790005
- Testing
- therapeutic play
- Where
- Turkey (Türkiye)
- Volunteers
- 92 people
- Sponsor
- Aydin Adnan Menderes University
Children With Liver Transplant
VIRTUAL REALITY GLASSES, CHILDREN WITH LIVER TRANSPLANTATION
The aim of the study is to determine the effect of SGG application on pain, anxiety/anxiety, fear and physiological variables during dressing in children aged 4-10 years with liver transplantation.
- Trial name
- NCT05420025
- Where
- Turkey (Türkiye)
- Volunteers
- 15 people
- Sponsor
- Firat University
Pregnancy, Postpartum
HIIT vs MICT During Pregnancy and Health and Birth Outcomes in Mothers and Children
Regular exercise during pregnancy and postpartum leads to health benefits for mother and child. Inactivity during pregnancy and after delivery is now treated as risky behavior.
- Conditions
- Pregnancy, Postpartum, Childbirth, Health Status
- Trial name
- HIIT MAMA (NCT05009433)
- Testing
- High intensity interval training program for pregnant women, Moderate intensity continuous training program for pregnant women, Standard obstetric care with extended education on healthy lifestyle
- Where
- Poland
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- Gdansk University of Physical Education and Sport