Clinical trials: Anxious-Depressive
Generalized Anxiety, Introspective & Anxiety-Prone Patient
Validation of a Rapid Screening Tool for Anxiety-depressive Disorders in Children, Adolescents and Young Adults Treated in Oncology. Multicenter Study.
In France today, it is estimated that one in every 850 people aged between 20 and 45 is a childhood cancer survivor (CCS), equivalent to around 40,000 to 50,000 people.
- Conditions
- Generalized Anxiety, Introspective & Anxiety-Prone Patient, Depression, Anxiety, Survivors of Childhood Cancer
- Trial name
- HARMONY-Tool (NCT07117058)
- Testing
- New rapid screening tool for anxiety and depressive disorders, SCARED-R-51 (Screen for Child Anxiety Related Emotional Disorders-Revised), HADS (Hospital Anxiety and Depression Scale)
- Where
- 7 sites in France
- Volunteers
- 545 people
- Sponsor
- Centre Hospitalier Universitaire de Saint Etienne
Aortic Stenosis, Anxiety
10-year Follow-up After Aortic Valve Replacement Surgery
There is a lack of data on patients self-reported outcomes (PROMs) on health-related quality of life (HRQoL)and symptoms on anxiety and depression 10 years after Surgical After Aortic Valve Replacement (SAVR), and patient…
- Conditions
- Aortic Stenosis, Anxiety, Depressive Symptoms, Quality of Life
- Trial name
- AVR-10year (NCT06255691)
- Volunteers
- 282 people
- Sponsor
- Oslo University Hospital
Suicidal Ideation, Depression
Population Screening Using Smartphone in Milpa Alta
The objective of this study is to make a suicide screening in the entire population of Milpa Alta (approximately 150,000 inhabitants), taking into account other outcomes such as depression, anxiety, alcohol and drugs.
- Conditions
- Suicidal Ideation, Depression, Depressive Disorder, Anxiety
- Trial name
- Smart-screen (NCT04067063)
- Testing
- Self-administered evaluation questionnaire
- Where
- Mexico
- Volunteers
- 150,000 people
- Sponsor
- Instituto de Investigación Sanitaria de la Fundación Jiménez Díaz
Obsessive Compulsive Disorder, Major Depressive Disorder
ON/OFF Stimulation and Impulsivity in Patients With Deep Brain Stimulators
The investigators propose a test of causality by examining a cohort of patients undergoing deep brain stimulation (DBS) within the ventral striatum.
- Trial name
- NCT01506206
- Where
- 2 sites in United States
- Sponsor
- Massachusetts General Hospital
Depressive Symptoms, Anxiety
Stay Well at Home: a Text-messaging Study Social Distancing
The investigators have developed supportive text-messages in English and Spanish to help people cope with the stress and anxiety of COVID-19 social distancing.
- Conditions
- Depressive Symptoms, Anxiety, COVID-19
- Trial name
- NCT04473599
- Testing
- Uniform random message delivery, Reinforcement learning message delivery, Mood ratings only
- Where
- United States
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- University of California, Berkeley
Depressive Symptoms, Anxiety State
Online Cognitive Behavioral Groupherapy for Mothers of Babies With Congenital Heart Disease
Introduction: Mothers of babies with congenital heart disease tend to have higher levels of depression, stress and anxiety. Currently, psychological support group technology has been a resource increasingly used by health…
- Conditions
- Depressive Symptoms, Anxiety State, Psychological Well-Being
- Trial name
- NCT05956249
- Testing
- Online group therapy, Control Group
- Where
- Brazil
- Volunteers
- 72 people
- Sponsor
- Instituto de Cardiologia do Rio Grande do Sul
Depressive Disorders, Anxiety Disorders
A Cognitive-Behavioral Intervention for Depression and Anxiety in COPD
The literature and our preliminary studies found that in COPD patients, psychosocial factors affect quality of life (QOL) and functioning more than would be expected given the severity of their disease.
- Conditions
- Depressive Disorders, Anxiety Disorders, Pulmonary Disease, Chronic Obstructive
- Trial name
- NCT00105911
- Testing
- Cognitive Behavioral Therapy
- Where
- United States
- Volunteers
- 222 people
- Sponsor
- US Department of Veterans Affairs
Anatomic Stage I Breast Cancer AJCC v8, Anatomic Stage IA Breast Cancer AJCC v8
Cognitive-Behavioral Stress Management Device for the Treatment of Anxiety and Depressive Symptoms in Patients With Stage I-III Breast or Lung Cancer
This phase II trial studies the effect of a digital application (app), BNT001, on cognitive-behavioral stress management in patients with stage I-III breast or lung cancer.
- Conditions
- Anatomic Stage I Breast Cancer AJCC v8, Anatomic Stage IA Breast Cancer AJCC v8, Anatomic Stage IB Breast Cancer AJCC v8, Anatomic Stage II Breast Cancer AJCC v8
- Trial name
- BNT001 (NCT04705025)
- Testing
- Cognitive Behavior Therapy, Interview, Quality-of-Life Assessment
- Where
- United States
- Volunteers
- 5 people
- Sponsor
- Jonsson Comprehensive Cancer Center
Postpartum Depression, Postpartum Anxiety
A Pilot Trial of the Reach Out, Stay Strong, Essentials for Mothers of Newborns (ROSE) Postpartum Depression Prevention Intervention in Pregnant Patients Admitted to Strong Hospital
This study is a pilot, single-center, randomized controlled trial. It will 1. determine feasibility and acceptability of an evidence-based intervention for prevention of postpartum depression with antepartum patients on a…
- Trial name
- NCT05225025
- Testing
- ROSE, Standard of Care
- Where
- United States
- Volunteers
- 45 people
- Sponsor
- University of Rochester
Stress, Psychological, Anxiety Disorders
Acceptability and Feasibility of an 8-week Online Mindfulness-Based Cognitive Therapy Program Among Undergraduate Students
Mental health problems -particularly depression- are the main cause of morbidity in young people (1), which has a known association with different health and social problems, such as increased alcohol consumption and drug…
- Conditions
- Stress, Psychological, Anxiety Disorders, Depression, Unipolar
- Trial name
- NCT05114824
- Testing
- Mindfulness-Based Cognitive Therapy
- Where
- Chile
- Volunteers
- 62 people, healthy volunteers welcome
- Sponsor
- Universidad de los Andes, Chile
Menopause, Anxiety
Internet-Delivered Cognitive Behaviour Therapy for Women with Perimenopausal Anxiety
The goal of this clinical trial is to design an online Cognitive Behavioural Therapy (CBT) and Acceptance Commitment Therapy (ACT) program and to learn if it can treat anxiety in women transitioning into menopause…
- Conditions
- Menopause, Anxiety, Depressive/Anxiety Symptoms, Perimenopause
- Trial name
- NCT06865066
- Testing
- e-CBT
- Where
- 2 sites in Canada
- Volunteers
- 25 people
- Sponsor
- Dr. Nazanin Alavi
Post-Traumatic Stress Disorders, Major Depressive Disorder
Repeated Ketamine Infusions for Comorbid PTSD and MDD in Veterans
Co-occurring post-traumatic stress disorder (PTSD) and major depressive disorder (MDD) is the most common response to trauma; it is associated with poor clinical outcomes and substantial human disability.
- Trial name
- NCT04032301
- Testing
- Ketamine, Normal Saline
- Where
- United States
- Volunteers
- 67 people, healthy volunteers welcome
- Sponsor
- University of Minnesota
PTSD, Generalized Anxiety Disorder
Feasibility and ML Training Investigation of the Senseye DT for Diagnosis of Adults with PTSD
The aim of this study is to obtain data on the feasibility of the Senseye Diagnostic Tool (DT) to assess the presence and severity of post-traumatic stress disorder (PTSD) symptoms.
- Conditions
- PTSD, Generalized Anxiety Disorder, Major Depressive Disorder
- Trial name
- NCT05717439
- Testing
- CAPS-5-R, Senseye DT
- Where
- 5 sites in United States
- Volunteers
- 338 people, healthy volunteers welcome
- Sponsor
- Senseye, Inc.
Depression, Anxiety
The Effect of Selective Serotonin Reuptake Inhibitor (SSRI) Treatment on Affective Symptoms and Fertility Treatment Outcome in Women Undergoing in Vitro Fertilization (IVF)
Women undergoing IVF show a high prevalence of depressive and anxiety symptoms. Furthermore, stress has harmful consequences on IVF and pregnancy outcomes. An immunological cascade was suggested to be involved in the process.
- Conditions
- Depression, Anxiety, In Vitro Fertilization
- Trial name
- NCT00989053
- Testing
- escitalopram
- Where
- Israel
- Volunteers
- 120 people
- Sponsor
- Tel-Aviv Sourasky Medical Center
Diabetes Mellitus, Type 2
Intervention for Reducing Psychiatric Symptoms and Metabolic Variables in Patients With Diabetes Mellitus (DM)
The purpose of this study is apply a Brief Intervention (PST) in Diabetic and Obesity patient in primary care of Mexico City to improve their depressive and anxious symptoms and stabilization of metabolic variables.
- Trial name
- DM (NCT02889172)
- Testing
- Problem Solving Therapy
- Where
- Mexico
- Volunteers
- 70 people
- Sponsor
- Instituto Nacional de Psiquiatría Dr. Ramón de la Fuente
Opioid-use Disorder, Anxiety Disorders
Digital Intervention to Treat Anxiety and Depression Among Persons Receiving Treatment for Opioid Use Disorder
The majority of opioid users meet criteria for anxiety and depressive disorders, but most substance use disorder treatment programs do not offer treatment for co-occurring mental health problems.
- Conditions
- Opioid-use Disorder, Anxiety Disorders, Depressive Disorder
- Trial name
- NCT05047627
- Testing
- Smartphone-Based Digital Intervention
- Where
- United States
- Volunteers
- 63 people
- Sponsor
- Trustees of Dartmouth College
Depressive Disorder, Somatoform Disorder
Physical Activity in Insurance Medicine: Effects on Patients With Psychiatric Disorders
We will conduct a randomized control trial to investigate whether and to what extent regular and guided group physical activity over 12 weeks (2 sessions à 1 hour/week) improves physical fitness and (physio-)psychological…
- Conditions
- Depressive Disorder, Somatoform Disorder, Anxiety Disorder, Personality Disorder
- Trial name
- PhysActIV (NCT01928264)
- Testing
- Physical activity
- Where
- Switzerland
- Volunteers
- 13 people
- Sponsor
- University Hospital, Basel, Switzerland
PTSD - Post Traumatic Stress Disorder
REVEAL Study - Diagnostic Testing for PTSD Using the Senseye Diagnostic Tool
The goal of the REVEAL PTSD study is to test how well the Senseye DT works as a diagnostic test for Post-traumatic Stress Disorder (PTSD) in adults 18 and older who are experiencing one or more symptoms that might be related to…
- Trial name
- NCT07280065
- Testing
- Senseye Diagnostic Tool (DT), Clinician Administered PTSD Scale for DSM-5, Revised Version
- Where
- 6 sites in United States, Australia
- Volunteers
- 1,900 people, healthy volunteers welcome
- Sponsor
- Senseye, Inc.
Major Depressive Disorder (MDD), Anxiety Disorder
Identification and Molecular Characterisation of Urban-environmental Stress Patterns Affecting Mental Illness
Mental disorders have become a major contributor to the global burden of non-communicable diseases, with disability-adjusted life years (DALYs) attributable to these conditions continuing to rise.
- Conditions
- Major Depressive Disorder (MDD), Anxiety Disorder, Alcohol Use Disorder (AUD)
- Trial name
- NCT07571226
- Testing
- wearable monitoring devices
- Where
- 3 sites in China
- Volunteers
- 680 people, healthy volunteers welcome
- Sponsor
- Huashan Hospital
Adjustment Disorder, Anxiety
Online MBCT for Adjustment Disorder During COVID-19: Efficacy, Mechanisms, and RCT
This study tested a 4-week, internet-based Mindfulness-Based Cognitive Therapy (MBCT) program designed to help people experiencing adjustment disorder during the COVID-19 pandemic.
- Conditions
- Adjustment Disorder, Anxiety, Depressive
- Trial name
- NCT07128017
- Testing
- Mindfulness-Based Cognitive Therapy (Internet-delivered), Progressive Muscle Relaxation (Internet-delivered), No Intervention - Waitlist Control
- Where
- Poland
- Volunteers
- 301 people
- Sponsor
- University of Warsaw