Clinical trials: Anxious-Depressive
Depression, Anxious Depression
Ketamine for Depression: An MRI Study
Ketamine has been shown to decrease symptoms of anxious depression quickly. This decrease has been shown to last for up to one month.
- Conditions
- Depression, Anxious Depression, Major Depressive Disorder
- Trial name
- NCT02544607
- Testing
- Ketamine, Magnetic Resonance Imaging (MRI)
- Where
- United States
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital
Depressive Disorders, Anxiety Disorders
A Cognitive-Behavioral Intervention for Depression and Anxiety in COPD
The literature and our preliminary studies found that in COPD patients, psychosocial factors affect quality of life (QOL) and functioning more than would be expected given the severity of their disease.
- Conditions
- Depressive Disorders, Anxiety Disorders, Pulmonary Disease, Chronic Obstructive
- Trial name
- NCT00105911
- Testing
- Cognitive Behavioral Therapy
- Where
- United States
- Volunteers
- 222 people
- Sponsor
- US Department of Veterans Affairs
Generalized Anxiety Disorder, Major Depressive Disorder
Development of Online EMDR Therapy System and Its Comparative Testing With Face-to-Face EMDR Therapy for Treatment of Anxiety and Depressive Disorders in Pakistan
This study aims at developing an online system for the remote delivery of EMDR therapy in Pakistan. Moreover, this study will compare the efficacy of online EMDR therapy with face-to-face EMDR therapy.
- Conditions
- Generalized Anxiety Disorder, Major Depressive Disorder, Social Anxiety Disorder, Somatic Symptom
- Trial name
- NCT05785312
- Testing
- Online EMDR Therapy System, Face to Face Eye Movement Desensitization & Reprocessing Therapy
- Where
- Pakistan
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Khushal Khan Khattak Univeristy, Karak, Pakistan
Anxiety Disorders, Mood Disorders
Treating Emotional Disorders in Primary Care With Psychological Techniques
The strong demand for primary care (PC) services in Spain exceeds resources. Part of this demand is due to the increasing number of anxiety, depression, and somatization disorders that affect the general population.
- Conditions
- Anxiety Disorders, Mood Disorders, Somatization Disorder, Pain Disorder
- Trial name
- PsychPC (NCT01903096)
- Testing
- Cognitive Behavioral Treatment, Primary Care Treatment As Usual
- Where
- Spain
- Volunteers
- 1,126 people
- Sponsor
- Psicofundación: Fundación Española para Promoción, Desarrollo Científico y Profesional de la Psicolo
Acquired Immunodeficiency Syndrome, Depressive Disorder
Psychosocial Correlates and Coping Strategies Associated With Long-Term Survival of HIV-Infected Children
Children and adolescents with HIV/AIDS are living well beyond life expectancy that was projected for them in the recent past. Little is known about the psychosocial variables that coincide with long-term survival of HIV/AIDS.
- Conditions
- Acquired Immunodeficiency Syndrome, Depressive Disorder, HIV Infections
- Trial name
- NCT00001435
- Where
- United States
- Volunteers
- 110 people
- Sponsor
- National Cancer Institute (NCI)
Depression - Major Depressive Disorder, Anxiety
Clinical Impact of an Anti-Inflammatory Diet in Anxiety and Depression With AI
The goal of this clinical trial is to evaluate the effectiveness of an anti-inflammatory dietary intervention on physical health, mental health, and cognitive functioning in individuals with clinically diagnosed anxiety and/or…
- Trial name
- NCT07398040
- Testing
- Anti-inflammatory diet, Control
- Where
- Spain
- Volunteers
- 60 people
- Sponsor
- Universidad de Zaragoza
Major Depressive Disorder, Anxiety
The Effects of Vilazodone on Glutamate in the Anterior Cingulate Cortex in Anxious Unipolar Depressives
The purpose of this study is to determine whether vilazodone is more effective than citalopram for the treatment of anxious depression.
- Conditions
- Major Depressive Disorder, Anxiety, Comorbidity
- Trial name
- NCT02028026
- Testing
- Vilazodone, Citalopram
- Where
- United States
- Sponsor
- Massachusetts General Hospital
Insulin Resistance, Low Birth Weight
Effects of 3 Months of Selective Serotonin Reuptake Inhibitor (SSRI)-Treatment on Metabolism and Hypothalamic-pituitary-adrenal (HPA)-Axis in Young Men Born With Low Birth Weight
Chronic stress has been proposed to be involved the development of western life-style diseases such as cardiovascular disease and type 2 diabetes (T2DM).
- Conditions
- Insulin Resistance, Low Birth Weight, Type 2 Diabetes, Cardiovascular Disease
- Trial name
- LBW-SSRI (NCT00971815)
- Testing
- Escitalopram
- Where
- Denmark
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Aarhus
Pulmonary Disease, COPD
The Virtual Reality Therapy as a Pulmonary Rehabilitation Supporting Method
This study evaluates the effectiveness of virtual reality (VR) therapy in the treatment of depression and anxiety symptoms in patients undergoing the pulmonary rehabilitation.
- Conditions
- Pulmonary Disease, COPD, Anxiety State, Stress
- Trial name
- NCT04601545
- Testing
- Pulmonary rehabilitation, Virtual therapeutic support
- Where
- 2 sites in Poland
- Volunteers
- 50 people
- Sponsor
- Wroclaw University of Health and Sport Sciences
Dysthymia, Anxiety Disorders
A Trial of Cognitive Behavioral Therapy in Familial Dysautonomia
To determine the effect of cognitive behavioral therapy (CBT) in the severity of anxiety and depression in adult patients with familial dysautonomia. Patients will be enrolled in an 8-week CBT program.
- Conditions
- Dysthymia, Anxiety Disorders, Familial Dysautonomia, Paroxysmal Hypertension
- Trial name
- NCT03013777
- Testing
- 8-week CBT Program
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- NYU Langone Health
Depression - Major Depressive Disorder, Generalised Anxiety Disorder
Effectiveness of Internet-based Unified Protocol (iUP) for Emotional Problems: A Randomized Controlled Trial
The goal of this clinical trial is to learn if an internet-based Unified Protocol (iUP) intervention is effective for treating depression and anxiety disorders in Hong Kong young adults aged 18-29 years.
- Conditions
- Depression - Major Depressive Disorder, Generalised Anxiety Disorder, Anxiety Disorder (Panic Disorder or GAD), Depressive and Anxiety Disorders
- Trial name
- NCT07908628
- Testing
- Internet-based Unified Protocol (iUP), Waitlist Control Group
- Where
- Hong Kong
- Volunteers
- 78 people
- Sponsor
- New Life Psychiatric Rehabilitation Association
Depressive Disorder, Anxiety Disorder
Group Intervention for Interpersonal Skills
The purpose of this study is to compare an individual state-of-the-art cognitive behavioral therapy (CBT) with CBT augmented by a group intervention for improving interpersonal skills, the Kiesler Circle Training (CBT+KCT), in…
- Trial name
- GRIPS (NCT06170801)
- Testing
- Kiesler Circle Training (KCT), Cognitive Behavioral Therapy (CBT)
- Where
- Germany
- Volunteers
- 158 people
- Sponsor
- Charite University, Berlin, Germany
Anxiety Disorders, Depressive Disorder
Problem Management Plus (PM+) in Chile: a Pilot Randomized Controlled Trial of a Psychological Transdiagnostic Intervention Delivered in Primary Health Care
This study aims to evaluate the implementation outcomes of a pilot randomized controlled trial and to assess the preliminary efficacy of Problem Management Plus (PM+) in reducing symptoms of depression and anxiety among users at…
- Trial name
- NCT06988332
- Testing
- Problem Management Plus (PM+)
- Where
- Chile
- Volunteers
- 56 people
- Sponsor
- University of Chile
PTSD - Post Traumatic Stress Disorder
REVEAL Study - Diagnostic Testing for PTSD Using the Senseye Diagnostic Tool
The goal of the REVEAL PTSD study is to test how well the Senseye DT works as a diagnostic test for Post-traumatic Stress Disorder (PTSD) in adults 18 and older who are experiencing one or more symptoms that might be related to…
- Trial name
- NCT07280065
- Testing
- Senseye Diagnostic Tool (DT), Clinician Administered PTSD Scale for DSM-5, Revised Version
- Where
- 6 sites in United States, Australia
- Volunteers
- 1,900 people, healthy volunteers welcome
- Sponsor
- Senseye, Inc.
Postpartum Depression
Escitalopram (Lexapro) for the Treatment of Postpartum Depression
The purpose of this study is to determine whether women with postpartum major depressive disorder (MDD) will experience a significant decrease in depressive symptoms from baseline over an eight-week treatment intervention with…
- Trial name
- LexaproPPD (NCT00833469)
- Testing
- Escitalopram
- Where
- United States
- Volunteers
- 7 people
- Sponsor
- Massachusetts General Hospital
Depressive Symptoms, Anxiety
COMET India Follow-up Trial
We are evaluating an online single-session intervention for mental health promotion among Indian college students.
- Conditions
- Depressive Symptoms, Anxiety, Happiness
- Trial name
- NCT05138120
- Testing
- Common Elements Toolbox
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Pennsylvania
Major Depressive Disorder, Depression
Testing a Transdiagnostic TMS Treatment Target
The goal of this clinical trial is to test a new brain stimulation treatment target for individuals with depression plus at least one additional psychiatric disorder.
- Conditions
- Major Depressive Disorder, Depression, Psychiatric Disorder, Mood Disorders
- Trial name
- T5 (NCT06282146)
- Testing
- transcranial magnetic stimulation
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Brigham and Women's Hospital
Post-Traumatic Stress Disorder, Chronic, Depressed Mood
An Interrupted Time-Series Pilot Trial of LGBTQ-Affirming Cognitive Processing Therapy for Interpersonal and Developmental Trauma
The researchers are testing a single-group cognitive-behavioral intervention for treating traumatic stress related to interpersonal and developmental trauma in LGBTQ adults.
- Conditions
- Post-Traumatic Stress Disorder, Chronic, Depressed Mood, Depressive and Anxiety Disorders, Anxiety
- Trial name
- NCT07863817
- Testing
- Cognitive Processing Therapy
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- University of Alabama at Birmingham
Obsessive Compulsive Disorder, Major Depressive Disorder
Integrating Pharmacogenomic Testing Into a Child Psychiatry Clinic
The purpose of this study is to examine the feasibility, acceptability, and utility of pharmacogenomic (PGX) testing (specifically for the cytochrome P450 2D6 and 2C19 genes) prior to initiating treatment with an antidepressant…
- Conditions
- Obsessive Compulsive Disorder, Major Depressive Disorder, Anxiety
- Trial name
- PGX (NCT02855580)
- Where
- United States
- Volunteers
- 71 people, healthy volunteers welcome
- Sponsor
- University of Florida
Burnout, Professional, Mental Health Wellness 1
Burn Out Among Medical Family Doctors
The main objective of this study is to assess the burnout prevalence among French general practitioners in private practice. As secondary outcomes, this study aim to measure the impact of sociodemographic variables…
- Conditions
- Burnout, Professional, Mental Health Wellness 1, Anxiety, Depressive Disorder
- Trial name
- BOUM (NCT04242862)
- Where
- France
- Volunteers
- 1,536 people
- Sponsor
- University Hospital, Clermont-Ferrand