Clinical trials: Anxious-Depressive
Post-Concussion Syndrome, Anxiety Disorders and Symptoms
Breath Control and Mindfulness for Post Concussion Anxiety and Depression: a Feasibility Study
Persistent-post-concussion symptoms (PPCS) is a condition that effects on average one in seven persons following a concussion. Anxiety and depression symptoms are experienced by over one-third of those with PPCS.
- Conditions
- Post-Concussion Syndrome, Anxiety Disorders and Symptoms, Depressive Symptoms
- Trial name
- NCT04708522
- Testing
- Breath Control - Equal Breathing Technique, Guided Mindfulness Exercise, Control
- Where
- Canada
- Volunteers
- 30 people
- Sponsor
- Western University, Canada
Anxiety Symptoms, Perceived Stress
The Effects of Probiotic Supplementation on State and Trait Stress, Anxiety, and Depression Symptoms in Stressed Adults
The goal of this randomized controlled trial is to learn if supplementation with the probiotic Lactobacillus reuteri DSM 17938 can reduce levels of trait and state perceived stress, anxiety, and depressive symptoms compared to a…
- Conditions
- Anxiety Symptoms, Perceived Stress, Depressive Symptoms
- Trial name
- NCT07216729
- Testing
- Lactobacillus reuteri DSM 17938
- Where
- United States
- Volunteers
- 150 people
- Sponsor
- University of Colorado, Boulder
Cancer, Anxiety
My Wellbeing Guide: A Novel Tool for Managing Stress and Improving Quality of Life
The purpose of this study is to examine the implementation and effectiveness of the psychosocial eHealth intervention, My Wellbeing Guide, on the proposed primary outcome, depressive symptoms, in patients diagnosed with cancer…
- Conditions
- Cancer, Anxiety, Depressive Symptoms
- Trial name
- R37 (NCT05369429)
- Testing
- My Wellbeing Guide
- Where
- United States
- Volunteers
- 6,516 people
- Sponsor
- Northwestern University
Attention Deficit Hyperactivity Disorder, Depression
Adult ADHD Symptoms, Depression, Anxiety, and Academic Performance in Medical Students
Attention-deficit/hyperactivity disorder (ADHD) is increasingly recognized to persist into adulthood, often impacting academic performance in university and professional education.
- Conditions
- Attention Deficit Hyperactivity Disorder, Depression, Anxiety, Academic Performance
- Trial name
- NCT07803224
- Volunteers
- 52 people
- Sponsor
- Assiut University
Unipolar Depression, Anxiety Disorders
Effects of Mindfulness Based Cognitive Therapy on Emotional Processing
Background: In the last 30 years mindfulness-based approaches have been extensively used for a variety of mental disorders, including affective disorders characterized by emotional instability.
- Conditions
- Unipolar Depression, Anxiety Disorders, Adjustment Disorders, Emotional Instability
- Trial name
- MESI (NCT03358056)
- Testing
- Mindfulness-Based Cognitive Therapy
- Where
- Spain
- Volunteers
- 30 people
- Sponsor
- Parc de Salut Mar
Cardiovascular Disease, Psychological Distress
Evaluation of a Personcentered Internet-based CBT Program for Stress, Anxiety and Depressive Symptoms in Patients With Cardiovascular Disease
To evaluate a nine-week adaptable and person-centred I-CBT program that can be directed towards stress, anxiety and depressive symptoms in persons with CVD.
- Trial name
- NCT04726722
- Testing
- internet-based cognitive behavioral theraphy
- Where
- Sweden
- Volunteers
- 215 people
- Sponsor
- University Hospital, Linkoeping
Mental Health Wellness 1, COVID
Telepsychoeducation for the Prevention of Emotional Distress in Professionals and Students From Essential Services in the Context of COVID-19
A pragmatic superiority randomized controlled trial comparing Telepsychoeducation plus personalized videos vs. Telepsychoeducation without personalized videos for the prevention of future emotional distress in professionals and…
- Conditions
- Mental Health Wellness 1, COVID, Emotional Distress, Depressive Symptoms
- Trial name
- NCT04632082
- Testing
- Telepsychoeducation with personalized videos, Telepsychoeducation without personalized videos
- Where
- Brazil
- Volunteers
- 2,200 people
- Sponsor
- Hospital de Clinicas de Porto Alegre
Stress Disorders, Post-Traumatic, Acute Stress Disorder
Post-traumatic Stress Injuries Among Paramedics and Emergency Dispatchers
As part of their work, emergency first responders, such as paramedics and emergency medical dispatchers are exposed daily to traumatic events.
- Conditions
- Stress Disorders, Post-Traumatic, Acute Stress Disorder, Anxiety Disorders, Depressive Disorder
- Trial name
- NCT04202042
- Testing
- Psychological first aid, Usual organisational intervention
- Where
- Canada
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Centre de Recherche de l'Institut Universitaire en santé Mentale de Montréal
Pregnancy, Mother
A Feasibility Study of AMOR; ADHD, Mothers Online Resources
The primary aim of this study is to investigate the feasibility of the program AMOR for pregnant women and new mothers with Attention Deficit Hyperactivity Disorder (ADHD), by examining adherence, credibility, treatment…
- Conditions
- Pregnancy, Mother, Women, Attention Deficit Disorder With Hyperactivity
- Trial name
- AMOR (NCT06679010)
- Testing
- Online group counseling
- Where
- Denmark
- Volunteers
- 31 people
- Sponsor
- University of Southern Denmark
Stress, Anxiety
Effects of High Ventilation Breathwork With Retention (HVBR) on Health
The investigators are conducting a randomised-controlled trial comparing high ventilation breathwork with retention (HVBR) to a breathwork placebo (paced breathing at 15breaths/min with brief retentions).
- Conditions
- Stress, Anxiety, Depressive Symptoms, Mental Wellbeing
- Trial name
- NCT06064474
- Testing
- High ventilation breathwork with retention (HVBR)
- Where
- United Kingdom
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- University of Sussex
Stress, Caregiver Burden
Self-Compassion to Enhance the Well-Being of Caregivers of Children With Physical Disabilities
The goal of this clinical trial is to test the feasibility, acceptability and preliminary social/emotional well-being outcomes of a tailored, online self-compassion-based resilience course for caregivers of children with physical…
- Conditions
- Stress, Caregiver Burden, Anxiety, Depressive Symptoms
- Trial name
- NCT06271824
- Testing
- Self-Compassion Based Resilient Caregiving Course
- Where
- United States
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- University of North Carolina, Chapel Hill
Depressive Symptoms, Anxiety
Promoting Maternal Mental Health and Wellbeing in Neonatal Intensive Care
This small randomized pilot study will evaluate feasibility and preliminary outcomes of an audio-delivered mindfulness program to reduce psychological distress for mothers with an infant in neonatal intensive care, as compared…
- Conditions
- Depressive Symptoms, Anxiety, Post-traumatic Stress Symptoms
- Trial name
- NCT03942627
- Testing
- Mindfulness Program, Infant Health Education Program
- Where
- United States
- Volunteers
- 76 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins University
Depression - Major Depressive Disorder, Anxiety
AcceXible Speech-Based Screening for Depression and Anxiety in University Students (UAQ, Mexico)
Major depressive disorder (MDD) and anxiety are increasingly prevalent among university student populations, yet early detection remains reliant on psychometric instruments tied to diagnostic criteria (e.g., PHQ-9, GAD).
- Trial name
- NCT07578142
- Testing
- Accexible
- Where
- Mexico
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Accexible
Depression, Anxiety
Pharmacogenomic Testing to Optimize Antidepressant Drug Therapy
A randomized controlled trial comparing pharmacogenomic guided versus standard pharmacist care to optimize antidepressant drug therapy.
- Conditions
- Depression, Anxiety, Major Depressive Disorder, Generalized Anxiety Disorder
- Trial name
- NCT03591224
- Testing
- Pharmacogenomic Testing, Pharmacist Standard of Care
- Where
- 2 sites in Canada
- Volunteers
- 213 people, healthy volunteers welcome
- Sponsor
- John Papastergiou Pharmacy Ltd
Anxiety Disorders, Depressive Disorder
Study on Mental Health Promoting Effects of Natural Psychotherapy for Adolescents
This randomized controlled trial aims to evaluate the efficacy of a universal intervention based on Natural Psychotherapy in reducing anxiety and depressive symptoms among primary and middle school students.
- Conditions
- Anxiety Disorders, Depressive Disorder, Mental Health
- Trial name
- NP-A-MHP (NCT07639476)
- Testing
- Multi-modal Nature-based Meditation, Intervention diary
- Where
- China
- Volunteers
- 3,000 people, healthy volunteers welcome
- Sponsor
- Beijing HuiLongGuan Hospital
Major Depressive Disorder, Generalized Anxiety Disorder
Mental Health Assessment and Prescribing by Alberta Pharmacists
This is a clinical trial evaluating the experimental intervention of enhanced pharmacist care by pharmacists with additional prescribing authorization (APA) in Alberta, for patients newly diagnosed with Major Depressive Disorder…
- Conditions
- Major Depressive Disorder, Generalized Anxiety Disorder, Pharmacist-Patient Relations
- Trial name
- MAP-AP (NCT04410575)
- Testing
- Standard Pharmacist Care, Reviewed Questionnaire tool results with participant, Patient Clinical Assessment
- Where
- Canada
- Volunteers
- 13 people, healthy volunteers welcome
- Sponsor
- University of Alberta
Anxiety, Mental Disorders
Keeping Well:Online Cognitive Behavioral Therapy (CBT) for Pregnant Women With Depressive Symptoms
Most depression during pregnancy is undetected and untreated although it is known to be harmful both to the woman herself and her future child.
- Conditions
- Anxiety, Mental Disorders, Postpartum Depression, Depressive Symptoms
- Trial name
- OnCBTDep (NCT01909167)
- Testing
- Online Cognitive Behavioral Therapy (CBT), Treatment as usual
- Where
- United Kingdom
- Sponsor
- Imperial College London
Anxiety, Depressive Symptoms
StriveWeekly: Self-Guided Online Intervention for Anxiety, Depression, and Stress in University Students
This study was a randomized controlled trial of an original online mental health promotion program. This study aimed to: 1) establish program effectiveness by examining symptom change between conditions and 2) examine predictors…
- Conditions
- Anxiety, Depressive Symptoms, Stress, Psychological
- Trial name
- NCT04361045
- Testing
- StriveWeekly
- Where
- United States
- Volunteers
- 1,631 people, healthy volunteers welcome
- Sponsor
- University of California, Los Angeles
Cardiovascular Diseases, Coronary Artery Disease
Supporting Methods in Cardiovascular Diseases Rehabilitation
The study evaluates how various therapeutic approaches perform in addressing depression, anxiety symptoms, and stress levels among patients in the second stage of cardiac rehabilitation.
- Conditions
- Cardiovascular Diseases, Coronary Artery Disease, Mood Disorders, Depressive Symptoms
- Trial name
- NCT06241534
- Testing
- Cardiac rehabilitation, Relaxation-therapeutic recordings, Virtual reality therapy
- Where
- Poland
- Volunteers
- 45 people
- Sponsor
- Wroclaw University of Health and Sport Sciences
Anxiety, Depressive Symptoms
The Effects of High-intensity Interval Training on Mental Health and Inflammation
The present study investigated the effects of high-intensity interval exercise training and placebo-exercise on mental health and inflammation using a randomized control trial.
- Conditions
- Anxiety, Depressive Symptoms, Inflammation
- Trial name
- NCT04118309
- Testing
- Exercise
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- McMaster University