Clinical trials: Anxious-Depressive
Anxiety Disorders, Generalized Anxiety Disorder
Mindful Self-compassion for Anxiety and Depression: Impact of Delivery Method
The study will compare the delivery of an 8-week Mindful Self-Compassion training, in-person against video-conference, on anxiety and depression symptom severity in patients with diagnosed anxiety disorders (generalized anxiety…
- Conditions
- Anxiety Disorders, Generalized Anxiety Disorder, Social Anxiety Disorder, Panic Disorder
- Trial name
- NCT07028216
- Testing
- Mindful Self-Compassion
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- Georgetown University
Post-Intensive Care Syndrome, Depressive Symptoms
Pilot Study of a Multidisciplinary Intervention in ICU Survivors at Risk for Psychological or Physical Morbidity
Pilot study of the feasibility and utility of an early, in-hospital multidisciplinary intervention in ICU survivors at risk for psychological and physical problems post-ICU stay
- Conditions
- Post-Intensive Care Syndrome, Depressive Symptoms, Anxiety, Physical Disability
- Trial name
- IMPRESS (NCT06118606)
- Testing
- Case-manager led multidisciplinary follow-up after intensive care
- Where
- 2 sites in Sweden
- Volunteers
- 41 people
- Sponsor
- Region Stockholm
Autism Spectrum Disorder, Depressive Disorder
Feasibility, Acceptability, and Preliminary Effectiveness of Cognitive Behavioral Therapy for Depression in Autistic Youth in Clinical Settings
The goal of this clinical trial is to learn if Cognitive Behavioral Therapy for Depression in Autistic Youth (CBT-DAY) can improve depressive symptoms and related mechanisms in autistic youth aged 11-17 years with depression…
- Conditions
- Autism Spectrum Disorder, Depressive Disorder, Anxiety Disorders
- Trial name
- CBT-DAY (NCT07755137)
- Testing
- CBT-DAY (Cognitive Behavioral Therapy for Depression in Autistic Youth), Treatment-as-Usual (TAU)
- Where
- United States
- Volunteers
- 140 people
- Sponsor
- Children's Hospital Los Angeles
Autism Spectrum Disorder, Depression - Major Depressive Disorder
Mental Health, Intellectual and Neurodevelopmental Disorder Detection With Artificial Intelligence Models
This study investigates whether AI-driven analysis of speech can accurately predict clinical diagnoses and assess risk for various mental or behavioral health conditions, including attention-deficit/hyperactivity disorder (ADHD)…
- Conditions
- Autism Spectrum Disorder, Depression - Major Depressive Disorder, Anxiety, Generalized, Bipolar Disorder (BD)
- Trial name
- MINDAIM (NCT06792175)
- Testing
- Solicue Machine Learning Models, Mercuria Machine Learning Models
- Where
- 2 sites in United States
- Volunteers
- 500 people
- Sponsor
- Psyrin Inc.
Critical Illness Recovery, Behavioral Health Concerns
Behavioral Health Collaborative Care Model in Post-ICU Clinic Family Pilot
This pilot study evaluates the feasibility and acceptability of implementing a Behavioral Health Collaborative Care Model (BH CoCM) for family members of ICU survivors.
- Conditions
- Critical Illness Recovery, Behavioral Health Concerns, Anxiety, Depression - Major Depressive Disorder
- Trial name
- NCT07390786
- Testing
- Behavioral Treatment
- Where
- United States
- Volunteers
- 150 people
- Sponsor
- Medical University of South Carolina
Stress Disorders, Post Traumatic, Brain Injuries
Mind-Body Skills Groups for the Treatment of War Zone Stress in Military and Veteran Populations
The purpose of this study is to determine whether participation in mind-body skills groups by veterans who have experienced a stressful war-related situation and have symptoms of posttraumatic stress disorder (PTSD), will improve…
- Conditions
- Stress Disorders, Post Traumatic, Brain Injuries, Depressive Disorder, Anxiety Disorders
- Trial name
- NCT01093053
- Testing
- Mind-Body Skills Groups, Standard Treatment
- Where
- United States
- Volunteers
- 108 people, healthy volunteers welcome
- Sponsor
- The Center for Mind-Body Medicine
Depressive Disorder, Anxiety Disorder
Feasibility of Process-based Therapy in a Naturalistic Setting
The main objective is to explore the feasibility of Process-based Therapy in a natural mental health care setting delivered by practitioners.
- Trial name
- PBaPP (NCT06530888)
- Testing
- Process-based Cognitive Behavioral Therapy (PBT), Routine practice (r-PT)
- Where
- Germany
- Volunteers
- 40 people
- Sponsor
- Goethe University
Depressive Symptoms
A Ten-Week Online Acceptance and Commitment Therapy Intervention for Family Caregivers of People With Dementia
This randomized controlled trial aims to assess the effects of a coach-guided ten-week videoconferencing acceptance and commitment therapy (ACT) program on mental health outcomes in depressed family caregivers of people with…
- Trial name
- NCT05043441
- Testing
- Acceptance and commitment therapy (ACT), Psychoeducation
- Where
- United States
- Volunteers
- 33 people
- Sponsor
- University of Alabama at Birmingham
Anxiety Depression, Placenta Previa
Anxiety and Depressive Symptoms in Placenta Previa / Accreta
placenta previa is an obstetric complication which is associated with depression and anxiety. As little is known about the emotional reaction to the diagnosis of placenta previa/accrete, a study is badly needed to estimate the…
- Trial name
- NCT05529381
- Where
- Egypt
- Volunteers
- 73 people
- Sponsor
- Assiut University
Autism Spectrum Disorder (ASD), Anxiety
Adapted Group Therapy Compared With Usual Care for Anxiety and Depression in Adults With an Autism Diagnosis
The goal of this clinical trial is to learn whether an adapted group therapy works to treat anxiety and depression in adults with an autism diagnosis. The therapy is a form of cognitive behavioral therapy (CBT).
- Conditions
- Autism Spectrum Disorder (ASD), Anxiety, Depression
- Trial name
- CoMind (NCT07880028)
- Testing
- Autism-adapted group cognitive behavioral therapy
- Volunteers
- 154 people
- Sponsor
- Lovisenberg Diakonale Hospital
Epilepsy, Depressive Symptoms
Adapting Project UPLIFT for Blacks in Georgia
Evaluate the efficacy of Project UPLIFT for reducing symptoms of depression and anxiety among African Americans at immediate posttest and after 3 months.
- Conditions
- Epilepsy, Depressive Symptoms, Anxiety Disorders and Symptoms
- Trial name
- NCT02909387
- Testing
- Project UPLIFT
- Where
- United States
- Volunteers
- 82 people
- Sponsor
- Morehouse School of Medicine
Depression - Major Depressive Disorder, Anxiety
AcceXible Speech-Based Screening for Depression and Anxiety in University Students (UAQ, Mexico)
Major depressive disorder (MDD) and anxiety are increasingly prevalent among university student populations, yet early detection remains reliant on psychometric instruments tied to diagnostic criteria (e.g., PHQ-9, GAD).
- Trial name
- NCT07578142
- Testing
- Accexible
- Where
- Mexico
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Accexible
Post-Traumatic Stress Disorder
Virtual Reality (VR) Therapy for Post-Traumatic Stress Disorder (PTSD)
It is proposed that using Virtual Reality as part of therapy will result in improvements in Post Traumatic Stress Disorder for Service Members with PTSD related to service in Iraq and/or Afghanistan.
- Trial name
- NCT00992953
- Testing
- Treatment as Usual, Virtual Reality Exposure with Stimulus Control
- Where
- 2 sites in United States
- Volunteers
- 136 people
- Sponsor
- Office of Naval Research (ONR)
Major Depression, Anxiety Disorder
Photobiomodulation to Alter Cerebral Blood Flow and to Affect the Emotional Status of Patients With Major Depression
A pilot study to evaluate the ability of photobiomodulation to alter cerebral blood flow in the frontal poles and to affect the emotional status of patients with major depression.
- Conditions
- Major Depression, Anxiety Disorder, Post-Traumatic Stress Disorder, Substance Abuse Disorder
- Trial name
- NCT00961454
- Testing
- Photobiomodulation with a super-luminous light emitting diode
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Massachusetts General Hospital
Depressive Disorder, Major, Post Traumatic Stress Disorder
A Randomized Control Trial Treating Depression With Yoga and Coherent Breathing Versus Walking in Veterans
The proposed study addresses a gap regarding the need for effective Major Depressive Disorder (MDD) treatments and the 40% of individuals treated with antidepressant medications that do not achieve full remission.
- Trial name
- NCT03489122
- Testing
- yoga, walking
- Where
- United States
- Volunteers
- 2 people
- Sponsor
- VA Office of Research and Development
Depressive Disorder, Anxiety Disorders
AI to Support Mental Health Case Management Providers
The goal of this clinical trial is to assess the effectiveness of an artificial intelligence (AI) platform for case managers in a nonprofit health system specializing in mental health and substance use disorder.
- Conditions
- Depressive Disorder, Anxiety Disorders, Substance Use Disorders, Post Traumatic Stress Disorder
- Trial name
- NCT06280170
- Testing
- Artificial Intelligence platform for case managers
- Where
- United States
- Volunteers
- 280 people, healthy volunteers welcome
- Sponsor
- Eleos Health
Bipolar Disorder
Self-compassion and Bipolar Disorder
Currently, pharmacotherapy is central in the management of bipolar disorder (BD), but does not guarantee satisfactory results for many patients.
- Trial name
- COMPASS-TB (NCT06497868)
- Where
- France
- Volunteers
- 10 people
- Sponsor
- University Hospital, Strasbourg, France
Postpartum Depression (PPD), Postpartum Anxiety
Investigation of TVNS Administration on Postpartum Mental Health
The aim of the study is to explore whether transcutaneous vagus nerve stimulation (tVNS) may be effective in preventing mood swings and depressive symptoms in the postpartum phase, as well as serving as a supplementary…
- Conditions
- Postpartum Depression (PPD), Postpartum Anxiety, Postpartum Sadness, Postpartum Blues
- Trial name
- NCT06682689
- Testing
- transcutaneous vagus nerve stimulation
- Where
- Germany
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- University Hospital Tuebingen
Depression, Anxiety
Impact of Ketamine On Depressive Symptoms In Patients Undergoing Lumbo-peritoneal Shunt Insertion
Postoperative depression is a perioperative psychological complication that severely affects patient recovery and quality of life. In extreme cases, it may lead to suicidal behavior.
- Trial name
- NCT06060210
- Testing
- normal Saline, Ketamine
- Where
- Egypt
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- Benha University
Post Partum Depression
Effect of Tele-consultation in Addition With Psychiatric Follow-up During COVID-19 in Women Who Have Medical History of Post-partum Depression
Women who were able to benefit from psychiatric follow-up during the quarantine by tele-consultation have a lower risk of anxious and depressive symptoms than those who did not receive follow-up.
- Trial name
- COVIDDEPERINAT (NCT04516668)
- Volunteers
- 250 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris