Clinical trials: Aortic Aneurysm
Abdominal Aortic Aneurysms
The Nellix® EndoVascular Aneurysm Sealing System for the Treatment of Infrarenal Abdominal Aortic Aneurysms
The purpose of this clinical study is to evaluate the safety and device performance of the Nellix® EndoVascular Aneurysm Sealing System (Nellix System) for the treatment of infrarenal abdominal aortic aneurysms.
- Trial name
- NCT02048514
- Testing
- The Nellix® EndoVascular Aneurysm Sealing System
- Where
- 4 sites in Colombia, Latvia and 2 more
- Volunteers
- 69 people
- Sponsor
- Endologix
Aneurysm, Abdominal Aortic
First-in-Human Trial of the A3-Shield System for Stabilizing Abdominal Aortic Aneurysms
This clinical trial evaluates the safety and feasibility of the A3-Shield implant for stabilising small abdominal aortic aneurysms in adult patients.
- Trial name
- PRINCIPIIS-FIH (NCT07330752)
- Testing
- A3-Shield Implantation
- Where
- Uzbekistan
- Volunteers
- 12 people
- Sponsor
- Angiolutions GmbH
Abdominal Aortic Aneurysm
TriVascular Post-Market Registry
This is a prospective observational post-market study of subjects receiving the Ovation™ or Ovation Prime™ Abdominal Stent Graft System ("Ovation™ or Ovation Prime™ Abdominal Stent Graft System Post-Market Study") in the…
- Trial name
- NCT01372709
- Testing
- Ovation™ or Ovation Prime™ Abdominal Stent Graft System
- Where
- 30 sites in Austria, Belgium and 6 more
- Volunteers
- 501 people
- Sponsor
- TriVascular, Inc.
Juxtarenal Aortic Aneurysm, Pararenal Aortic Aneurysm
Pilot Study of the Endologix Fenestrated Stent Graft System
The purpose of this study is to determine whether the Endologix fenestrated stent graft system is safe and feasible in the endovascular repair of juxtarenal or pararenal aortic aneurysm.
- Trial name
- NCT01437215
- Testing
- Ventana Fenestrated Stent Graft System
- Where
- 2 sites in Chile, New Zealand
- Volunteers
- 15 people
- Sponsor
- Endologix
Aneurysm Thoracic, Dissection of Aorta, Thoracic
TBE Zone 2 PMS in Japan
The goal of this surveillance is to confirm the TBE device's safety and efficacy in patients treated with proximal landing in Zone 2 in the post-marketing period.
- Conditions
- Aneurysm Thoracic, Dissection of Aorta, Thoracic, Trauma
- Trial name
- NCT07049913
- Testing
- Gore® TAG® Thoracic Aortic Branch Stent Graft System
- Where
- Japan
- Volunteers
- 200 people
- Sponsor
- W.L.Gore & Associates
Abdominal Aortic Aneurysm, AAA
Endurant Evo International Clinical Trial
The purpose of this trial is to evaluate the safety and effectiveness of the Endurant Evo Abdominal Aortic Aneurysm (AAA) Stent graft system for endovascular treatment of subjects with infrarenal abdominal aortic or aortoiliac…
- Trial name
- NCT02461524
- Testing
- Endurant Evo AAA Stent Graft System, Endovascular aneurysm repair (EVAR)
- Where
- 9 sites in Austria, Belgium and 3 more
- Volunteers
- 69 people
- Sponsor
- Medtronic Cardiovascular
Aortic Aneurysm, Aortic Aneurysm Abdominal
Prophylactic Suture Line Sealing With NE'X Glue R-eco in Cardiac and Vascular Surgery
This clinical study aims to evaluate the effectiveness and safety of using NE'X Glue R-eco to seal suture lines. The adhesive will be applied to reduce the risk of suture line bleeding in cardiac or vascular repair surgeries, a…
- Conditions
- Aortic Aneurysm, Aortic Aneurysm Abdominal, Valve Stenoses, Aortic, Valve Regurgitation, Mitral
- Trial name
- CLOSURE (NCT06918496)
- Testing
- Surgical placement of a prosthetic or biologic graft (patch), or an allograft for cardiac and (cardio)vascular repair.
- Where
- 2 sites in Belgium, Poland
- Volunteers
- 60 people
- Sponsor
- Grena Biomed Limited
Abdominal Aortic Aneurysms, Iliac Aneurysms
Zenith® Low Profile AAA Endovascular Graft
This extended investigation is to provide continued physician access to the device and collect confirmatory safety and effectiveness data.
- Conditions
- Abdominal Aortic Aneurysms, Iliac Aneurysms, Aorto-iliac Aneurysms
- Trial name
- NCT02557659
- Testing
- Zenith Low Profile AAA Endovascular Graft
- Where
- 22 sites in United States
- Sponsor
- Cook Group Incorporated
Aortic Aneurysm, Thoracic
VALIANT CAPTIVIA Post-market Registry
The Valiant Thoracic Stent Graft has been preloaded on the new Captivia Delivery System (Captivia). This new delivery system was CE marked on September 14th, 2009 and was commercially released in the European Union on October…
- Trial name
- VCOUS (NCT01181947)
- Testing
- TEVAR
- Where
- 15 sites in Austria, Germany and 5 more
- Volunteers
- 100 people
- Sponsor
- Medtronic Cardiovascular
Abdominal Aortic Aneurysms
AAA Registry: Clinical Outcomes of Highly Angulated anatomY Treated With the Aorfix™ Stent Graft
The ARCHYTAS Registry is a long-term, global, multicenter, non-randomized, prospective, registry designed to collect "on-label" data in real world clinical settings on patients undergoing endovascular repair with the latest…
- Trial name
- ARCHYTAS (NCT02480595)
- Testing
- Stent Graft
- Where
- 37 sites in Czechia, Germany and 4 more
- Volunteers
- 500 people
- Sponsor
- Lombard Medical
Thoracic Aortic Aneurysm
Valor II: The Valiant Thoracic Stent Graft System Clinical Study
This study was designed to study safety and effectiveness of the Valiant Thoracic Stent Graft to treat thoracic aortic aneurysms.
- Trial name
- NCT00413231
- Testing
- Valiant Thoracic Stent Graft System
- Where
- 26 sites in United States
- Volunteers
- 160 people
- Sponsor
- Medtronic Cardiovascular
Infrarenal Abdominal Aortic Aneurysms, Aortoiliac Aneurysms
HORIZON CE Pivotal Study to Treat Abdominal Aortic Aneurysm
Clinical Investigation Design A prospective, open-label, non-randomized, interventional clinical study, sponsored by Endospan Ltd. Patients will be followed-up for five years.
- Trial name
- NCT02087501
- Testing
- Horizon™ Abdominal Aortic Aneurysm Stent Graft System
- Where
- 7 sites in Italy, Netherlands and 2 more
- Volunteers
- 30 people
- Sponsor
- Endospan Ltd.
Abdominal Aortic Aneurysm, Aorto-iliac Aneurysm
Zenith® Spiral-Z® AAA Iliac Leg Graft Post-market Registry
The purpose of this registry is to obtain case reports of physician experience with the Spiral-Z® graft under routine clinical care.
- Trial name
- NCT01540643
- Testing
- Iliac Leg Graft
- Where
- 31 sites in United States, Canada
- Volunteers
- 600 people
- Sponsor
- Cook Group Incorporated
Thoracic Aortic Aneurysms
Post-Approval Clinical Study of the Talent Thoracic Stent Graft to Treat Thoracic Aortic Aneurysms (THRIVE)
The purpose of this study is to evaluate the long-term safety and effectiveness of the Talent Thoracic Stent Graft System for treatment of descending thoracic aneurysms (DTA)following U.S. market approval.
- Trial name
- THRIVE (NCT00805948)
- Testing
- Talent Thoracic Stent Graft System
- Where
- 26 sites in United States
- Volunteers
- 349 people
- Sponsor
- Medtronic Cardiovascular
Aortic Aneurysm, Abdominal
Endurant Stent Graft Natural Selection Global Postmarket Registry
The purpose of ENGAGE is to prospectively collect global 'real world' data on the Endurant Stent Graft System from AAA subjects.
- Trial name
- ENGAGE (NCT00870051)
- Testing
- Endurant Stent Graft
- Where
- 80 sites in Argentina, Australia and 28 more
- Volunteers
- 1,266 people
- Sponsor
- Medtronic Cardiovascular
Cardiac Surgery, Coronary Artery Bypass Grafting
Pharmacokinetics of AP214 Acetate in Patients Undergoing Cardiac Surgery
The purpose of the present research study is to investigate the pharmacokinetics, as well as safety, tolerability and pharmacodynamics of different ascending dosing regimens of AP214 in patients undergoing cardiac surgery.
- Conditions
- Cardiac Surgery, Coronary Artery Bypass Grafting, Valve Surgery, Aortic Root or Ascending Aortic Aneurysm Repair Surgery
- Trial name
- NCT00903604
- Testing
- AP214
- Where
- 2 sites in Denmark
- Volunteers
- 42 people
- Sponsor
- Action Pharma A/S
Abdominal Aortic Aneurysm (AAA)
ACZ885 for the Treatment of Abdominal Aortic Aneurysm
This study was designed to assess the safety, tolerability and efficacy of ACZ885 on aneurysmal growth rate in subjects with abdominal aortic aneurysms (AAA).
- Trial name
- AAA (NCT02007252)
- Testing
- ACZ885
- Where
- 9 sites in United States, Denmark and 3 more
- Volunteers
- 65 people
- Sponsor
- Novartis Pharmaceuticals
Aortic Dissection, Intramural Hematoma
DARTS I Feasibility Study
The objective of this study is to investigate the feasibility and clinical benefits of the AMDS to treat patients with acute DeBakey type I dissections and/or intramural hematomas (IMH) involving the ascending aorta and aortic…
- Trial name
- DARTS I (NCT03035643)
- Testing
- AMDS
- Where
- 5 sites in Canada
- Volunteers
- 40 people
- Sponsor
- Ascyrus Medical LLC.
Abdominal Aneurysm
AneuRx Post Market Study in the Treatment of AAA
The aorta is a large blood vessel that carries blood away from the heart to the organs in the rest of the body. An aneurysm is a weakening in the artery wall that will become a bulge in the aorta.
- Trial name
- NCT00604552
- Testing
- AneuRx Stent Graft
- Where
- 8 sites in United States
- Volunteers
- 349 people
- Sponsor
- Medtronic Cardiovascular
Aortic Dissection
ARISE: Evaluation of the GORE® Ascending Stent Graft in the Treatment of DeBakey Type I/II Aortic Dissection
Assess the feasibility of the treatment of DeBakey Type I/II aortic dissections with the GORE® Ascending Stent Graft
- Trial name
- NCT02380716
- Testing
- GORE® Ascending Stent Graft
- Where
- United States
- Volunteers
- 21 people
- Sponsor
- W.L.Gore & Associates