Clinical trials: Aortic Arch Aneurysm
Thoracoabdominal Aortic Aneurysm, Aortic Arch Aneurysm
Evaluation of Branch Endografts in the Treatment of Aortic Aneurysms
Zenith t-Branch Study Cohort: The purpose of this study is to collect information on the Cook Zenith t-Branch endovascular stent-graft system and the Terumo Arch Branch for the treatment of aortic aneurysms.
- Trial name
- NCT01524211
- Testing
- Zenith® t-Branch, Terumo Arch Branch
- Where
- United States
- Volunteers
- 235 people
- Sponsor
- Baptist Health South Florida
Thoracic Aortic Aneurysm, Thoracic Aortic Dissection
ENDOBARC-S Study: "Endovascular Branched Stent-grafts for Aortic ARCh Pathologies in Spain"
The ENDOBARC-S post-market clinical follow-up study is undertaken to evaluate the prevention of death related to aortic arch pathologies when treated by branch stent graft systems (Nexus stent-graft system®, Relay Branch® or…
- Conditions
- Thoracic Aortic Aneurysm, Thoracic Aortic Dissection, Stent-Graft Endoleak, Stent-Graft Stenosis
- Trial name
- NCT05309707
- Testing
- Endovascular exclusion
- Where
- Spain
- Volunteers
- 100 people
- Sponsor
- Vascular Investigation Network Spanish Society for Angiology and Vascular Surgery
Aorta Dissection, Aorta Aneurysm
Total Endovascular Aortic Arch Re-construction Study(TEARS)
The purpose of this study is to investigate the short to mid term efficacy and safety of a newly-developed branched stent graft in patients who had complex aortic lesions, such as ascending aortic/arch aneurysm, pseudo-aneurysm…
- Trial name
- NCT01496833
- Testing
- Ankura Branched/Fenestrated Stent Graft
- Where
- China
- Volunteers
- 50 people
- Sponsor
- Xijing Hospital
Aortic Arch Aneurysm, Penetrating Aortic Ulcer
Concave Supra-arch Branched Stent-Graft System for Endovascular Treatment of Aortic Arch Diseases
The objective of the study is to evaluate the safety and efficacy of the Lifetech Concave Supra-arch Branched Stent-Graft System for Endovascular Treatment of Aortic Arch Diseases
- Trial name
- NCT06520774
- Testing
- Concave Supra-arch Branched Stent-Graft System
- Where
- 17 sites in China, Germany
- Volunteers
- 103 people
- Sponsor
- Lifetech Scientific (Shenzhen) Co., Ltd.
Aortic Aneurysm, Thoracic
NICardipine Neuroprotection in AortiC Surgery (NICNACS)
Objective The objective of this study is to discover whether an infusion of nicardipine is able to reduce the time taken to achieve electrocerebral silence (ECS) during cardiopulmonary bypass (CPB) for aortic surgery.
- Trial name
- NICNACS (NCT00508118)
- Testing
- Nicardipine, 0.9% saline
- Where
- United States
- Volunteers
- 7 people
- Sponsor
- Duke University
Aortic Aneurysm, Aortic Aneurysm and Dissection
A Study to Evaluate the Safety and Effectiveness of the Rapidlink Device When Used in Patients Undergoing an Open Surgical Procedure to Repair the Aorta
The Goal of this Clinical Study is to evaluate the safety and effectiveness of the Rapidlink device in the repair or replacement of the supra-aortic vessels during open surgical repair of aortic disease affecting the thoracic…
- Conditions
- Aortic Aneurysm, Aortic Aneurysm and Dissection, Aortic Diseases, Aneurysm of Aorta, Thoracic
- Trial name
- RAPID (NCT07078383)
- Testing
- Rapidlink
- Where
- 21 sites in United States, Austria and 3 more
- Volunteers
- 150 people
- Sponsor
- Vascutek Ltd.
Aortic Arch Aneurysm
Homemade Fenestrated Physician-modified Stent-grafts for Arch Aortic Degenerative Aneurysm
The aim was to evaluate early and medium-term outcomes of single and double fenestrated physician-modified endovascular grafts (PMEGs) for endovascular aortic arch degenerative aneursym repair.
- Trial name
- NCT04809896
- Where
- France
- Volunteers
- 200 people
- Sponsor
- University Hospital, Montpellier
AKI
Protection From Acute Kidney Injury (AKI) With Basis™ Treatment
This study is a single-center, prospective, randomized, double-blinded, placebo-controlled phase II clinical trial to evaluate the efficacy of "NAD+ supplementation" with Basis™ (Nicotinamide Riboside and Pterostilbene) in…
- Trial name
- NCT04342975
- Testing
- Nicotinamide Riboside + Pterostilbene
- Where
- United States
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
Aortic Dissection, Acute Lung Injury/Acute Respiratory Distress Syndrome (ARDS)
Improvement of Pulmonary Insufficiency After Aortic Dissection With Sivelestat Sodium
Aortic dissection (AD) is one of the most dangerous cardiovascular emergencies, with rapid onset, rapid progression, high fatality rate, and a variety of life-threatening complications.
- Trial name
- IPIADSS (NCT05343338)
- Testing
- Sivelestat sodium
- Where
- China
- Volunteers
- 168 people
- Sponsor
- First Affiliated Hospital Xi'an Jiaotong University
Aortic Aneurysm and Dissection
Guo's Endovascular Aortic Arch Replacement of Aortic Dissection by WeFlow-Tribranch Endoprothesis: a Multicenter Pilot Study(GRAFT Study)
To explore the effect and prognosis of endovascular interventional therapy in high-risk patients with aortic arch dissection and aneurysm
- Trial name
- NCT05754541
- Testing
- WeFlow-Tribranch Aortic Arch Stent Graft System
- Where
- 4 sites in China
- Volunteers
- 20 people
- Sponsor
- Hangzhou Endonom Medtech Co., Ltd.
Thoracic Aortic Dissection
Prospective Study for Aortic Arch Therapy With stENt-graft for Chimney technologY（PATENCY）
A prospective, multi-centre, objective performance criteria clinical trial to evaluate the safety and efficacy of Artery Stent Graft System manufactured by Lifetech Scientific (Shenzhen) Co., LTD.
- Trial name
- NCT03767777
- Testing
- Artery Stent Graft System
- Where
- 21 sites in China
- Volunteers
- 150 people
- Sponsor
- Lifetech Scientific (Shenzhen) Co., Ltd.
Aneurysm, Dissection
PANTHER Study of Terumo Aortic Knitted and Woven Grafts, and Cardiovascular Patches
The purpose of this registry is to collect safety and performance data on all commercially available Terumo Aortic knitted and woven grafts, and cardiovascular patches in standard clinical practice.
- Conditions
- Aneurysm, Dissection, Aortic Root Aneurysm, Aortic Root Dissection
- Trial name
- PANTHER (NCT04545502)
- Testing
- Gelsoft Plus Vascular Graft, Vascular Bypass Graft, Cardiovascular Patch
- Where
- 30 sites in United States, Belgium and 4 more
- Volunteers
- 2,000 people
- Sponsor
- Vascutek Ltd.
Aortic Dissection
Study on the Aortic Arch Single Branch Stent Graft System
The objective of the study is to evaluate the Safety and Efficacy of Aortic Arch Single Branch Covered Stent System for Aortic Dissection Involving the Aortic Arch
- Trial name
- NCT06915545
- Testing
- Aortic Arch Single Branch Covered Stent System
- Where
- China
- Volunteers
- 135 people
- Sponsor
- Lifetech Scientific (Shenzhen) Co., Ltd.
Aneurysm of Aortic Arch
Prospective Randomized Study of Brain Protection During Aortic Arch Replacement
The purpose of this research study is to evaluate two standard approaches of supplying blood and oxygen to your brain during open heart surgery.
- Trial name
- NCT00606190
- Testing
- Retrograde brain perfusion, Antegrade brain perfusion
- Where
- United States
- Volunteers
- 123 people, healthy volunteers welcome
- Sponsor
- The Cleveland Clinic
Aortic Dissection, Aneurysm, Aortic Arch
Concave Supra-arch Branched Stent-Graft System for Treatment of Aortic Arch Diseases
There are no endoluminal stent systems available on the Chinese market for the effective treatment of aortic arch lesions (involving aortic arch aneurysms, aortic coarctation, aortic pseudoaneurysms, aortic ulcers, and intermural…
- Conditions
- Aortic Dissection, Aneurysm, Aortic Arch, Aortic Pseudoaneurysm, Aortic Ulcer, Penetrating
- Trial name
- NCT05996354
- Testing
- Concave Supra-arch Branched stent-graft system
- Where
- 3 sites in China
- Volunteers
- 10 people
- Sponsor
- China National Center for Cardiovascular Diseases
Aortic Dissection
Optimal Strategy for Repair of Type A Acute Aortic Dissection
Acute type A aortic dissection (TAAD) persists as a clinicopathologic entity with high lethality in the current era. Several procedures are presently used to repair the TAAAD.
- Trial name
- TARAD (NCT05912608)
- Testing
- Conservative TAAAD-R, Extensive TAAAD-R
- Where
- France
- Volunteers
- 900 people
- Sponsor
- Centre Cardiologique du Nord
Thoracic Aortic Aneurysm, Penetrating Aortic Ulcers (PAUs)
MBA Early Feasibility Study
The MBA 25-04 study is a prospective, multicenter, non-randomized, single-arm, early feasibility study designed to assess the initial safety of the MBA device through five years following the index endovascular procedure.
- Conditions
- Thoracic Aortic Aneurysm, Penetrating Aortic Ulcers (PAUs), Thoracic Aortic Dissection, Pseudoaneurysm
- Trial name
- NCT07564375
- Testing
- GORE® Multibranch Arch Endoprosthesis, GORE® Ascending Stent Graft
- Where
- 3 sites in United States
- Volunteers
- 20 people
- Sponsor
- W.L.Gore & Associates
Aortic Aneurysm, Thoracic, Aorta, Lesion
Evaluation of the GORE® TBE Device in the Treatment of Lesions of the Aortic Arch and Descending Thoracic Aorta, Zone 0/1
The objective of this study is to determine whether the GORE® TAG® Thoracic Branch Endoprosthesis is safe and effective in treating lesions of the aortic arch and descending thoracic aorta.
- Trial name
- SSB 11-02 (NCT02777528)
- Testing
- GORE® TAG® Thoracic Branch Endoprosthesis, Revascularization Procedure
- Where
- 39 sites in United States, Japan
- Volunteers
- 79 people
- Sponsor
- W.L.Gore & Associates
Juxtarenal Aortic Aneurysm, Suprarenal Aortic Aneurysm
Evaluation of the Cook Custom Aortic Endograft, the Zenith t-Branch Endovascular Graft, and Surgeon-Modified Endograft in Treating Aortic Pathologies
This is a single-center study to evaluate the safety and effectiveness of three investigational devices, the Cook Custom Aortic Endograft, the Zenith t-Branch Endovascular Graft, and the Surgeon-Modified Endografts in the…
- Conditions
- Juxtarenal Aortic Aneurysm, Suprarenal Aortic Aneurysm, Thoracoabdominal Aortic Aneurysm, Penetrating Aortic Ulcer
- Trial name
- NCT02043691
- Testing
- Cook Custom Aortic Endograft, Zenith t-Branch Endovascular Graft, Surgeon-Modified Endograft
- Where
- United States
- Volunteers
- 410 people
- Sponsor
- University of Alabama at Birmingham
Aortic Dissection
Hemiarch vs Extended Arch in Type 1 Aortic Dissection
HEADSTART is a prospective, open-label, non-blinded, multicenter, randomized controlled trial that compares a composite of mortality and re-intervention in patients undergoing hemiarch and extended arch repair for acute DeBakey…
- Trial name
- HEADSTART (NCT03885635)
- Testing
- Hemiarch repair, Extended arch repair
- Where
- 5 sites in Canada
- Volunteers
- 50 people
- Sponsor
- Ottawa Heart Institute Research Corporation