Clinical trials: Aortic Valve Surgery, open to volunteers
Coronary Artery Bypass Grafting, Heart Valve Disease
LLM-Based Intelligent Health Management Assistant in Life-Cycle Health Management of Cardiac Surgery Patients
This is a single-center, prospective, randomized, open-label, parallel-controlled clinical study to evaluate the effectiveness of a large language model (LLM)-based intelligent health management assistant in the life-cycle health…
- Conditions
- Coronary Artery Bypass Grafting, Heart Valve Disease, Aortic Aneurysm, Aortic Dissection
- Trial name
- cFT-LLM (NCT07521488)
- Testing
- LLM-Based Intelligent Health Management Assistant
- Where
- China
- Volunteers
- 500 people
- Sponsor
- Beijing Anzhen Hospital
Aortic Valve Regurgitation, Aortic Root Aneurysm
Clinical Evaluation of the Free Margin Cusp Sizer (CALIBRATE)
The objective of this study is to investigate safety and performance of the Free Margin Cusp sizer. The device will be used during aortic valve repair and sparing procedures as a caliper to measure the aortic valve free margin…
- Trial name
- CALIBRATE (NCT04797572)
- Testing
- Free Margin Cusp Sizer
- Where
- Belgium
- Volunteers
- 120 people
- Sponsor
- Cliniques universitaires Saint-Luc- Université Catholique de Louvain
Symptomatic Severe Aortic Stenosis
Surgical vs Transcatheter Aortic Valve Replacement in YOUNG Patients
The study objective is to demonstrate that the clinical outcomes of the Myval balloon-expandable THV series are non-inferior to those of SAVR in patients with symptomatic severe aortic stenosis aged 65 to 75 years.
- Trial name
- START YOUNG (NCT06861361)
- Testing
- Myval balloon-expandable THV Series, Surgical bioprosthetic valve
- Where
- 49 sites in Austria, Estonia and 12 more
- Volunteers
- 1,180 people
- Sponsor
- Ceric Sàrl
Aortic Valve Stenosis
Prizvalve Pro™ Transcatheter Aortic Valve Replacement Study
The purpose of this clinical trial is to evaluate the safety and efficacy of the Prizvalve Pro™ transcatheter aortic valve system in the treatment of patients with severe aortic stenosis who are at high risk of surgery or who are…
- Trial name
- NCT05864456
- Testing
- Prizvalve Pro™ transcatheter aortic valve system
- Where
- China
- Volunteers
- 73 people
- Sponsor
- Shanghai NewMed Medical Co., Ltd.
Aortic Aneurysm and Dissection, Coronary Artery Disease (CAD)
Effects of Myofascial Release on Cardiac Patients After Median Sternotomy
After deciding to join this study and signing the informed consent form, participants will undergo the following interventions: All participants will receive a preoperative assessment (Tp) before surgery.
- Conditions
- Aortic Aneurysm and Dissection, Coronary Artery Disease (CAD), Valve Heart Disease
- Trial name
- NCT07649330
- Testing
- myofascial release+Routine Physical Therapy, Routine Physical therapy
- Where
- Taiwan
- Volunteers
- 50 people
- Sponsor
- Siou-Pin Huang
Coronary Artery Disease, Aortic Valve Stenosis
Personalized Activity Intervention in Rehabilitation After Cardiac Operations (the PACO Trial)
The PACO trial is a randomized clinical trial conducted in Heart Centers of Kuopio and Turku university hospitals. The coronary artery disease, aortic valve stenosis and mitral valve insufficiency patients preparing for elective…
- Conditions
- Coronary Artery Disease, Aortic Valve Stenosis, Mitral Valve Insufficiency
- Trial name
- PACO (NCT03470246)
- Testing
- PACO intervention for CABG patients, PACO intervention for AVR patients, PACO intervention for MVR patients
- Where
- Finland
- Volunteers
- 540 people
- Sponsor
- Kuopio University Hospital
Valve Disease, Heart, Atrial Fibrillation (AF)
Apixaban VS Warfarin in AF Pts First Three Months After Repair or BIO AVR MVR
SAFE-HEART is a single-centre, randomized controlled trial comparing the safety and efficiency of Apixaban versus Warfarin in the early period (3 months) after repair or bioprosthetics of the mitral and aortic valve cardiac…
- Conditions
- Valve Disease, Heart, Atrial Fibrillation (AF), Valve Replacement Surgery, Aortic Valve Surgery
- Trial name
- SAFE-HEART (NCT07434661)
- Testing
- Apixaban, Warfarin
- Where
- Russia
- Volunteers
- 120 people
- Sponsor
- Meshalkin Research Institute of Pathology of Circulation
Prosthetic Valve Thrombosis
Assessment of TRanscathetEr and Surgical Aortic BiOprosthetic Valve Thrombosis and Its TrEatment With Anticoagulation
This is a prospective study designed to evaluate the structural and functional integrity of transcatheter or surgical bioprosthetic valves with multimodality imaging.
- Trial name
- RESOLVE (NCT02318342)
- Testing
- Warfarin
- Where
- United States
- Volunteers
- 3,000 people
- Sponsor
- Cedars-Sinai Medical Center
Aortic Stenosis
Transfemoral Transcatheter Aortic Valve Implementation at Hospital Without On-site Cardiac Surgery: Early Clinical Outcome in Patients With Prohibitive Surgical Risk.
Study design: single arm, interventional and multicenter study. The objectives are evaluate Safety and efficacy of TAVI in Department of Cardiology without on site cardiac Surgery for symptomatic severe aortic valve stenosis by…
- Trial name
- NCT05886517
- Testing
- Transfemoral transcatheter aortic valve implementation
- Where
- 4 sites in Italy, Spain
- Volunteers
- 200 people
- Sponsor
- AUSL Romagna Rimini
Postoperative Atrial Fibrillation
Statin Therapy With Atorvastatin in Surgical Aortic Valve Replacement
Statins have rapid and significant actions that have potentially important (but not yet proven) implications for postoperative atrial fibrillation and cardiac protection in patients undergoing cardiac surgery.
- Trial name
- STARC (NCT05076019)
- Testing
- Atorvastatin 80mg
- Where
- Denmark
- Volunteers
- 266 people
- Sponsor
- Odense University Hospital