Clinical trials: Aphakia
Aphakia, Corneal Astigmatism
Evaluation of the Safety and Performance of the HARMONI® Toric Lens
The purpose of this study was to evaluate the safety and effectiveness of the HARMONI® Modular Intraocular Lens System with a toric optic (HMTIOL) in subjects with pre-existing corneal astigmatism in need of cataract surgery.
- Conditions
- Aphakia, Corneal Astigmatism, Cataract
- Trial name
- NCT03050697
- Testing
- HARMONI® Modular Toric Intraocular Lens, Cataract extraction with intraocular lens (IOL) implantation
- Where
- New Zealand
- Volunteers
- 16 people
- Sponsor
- ClarVista Medical
Aphakia, Cataract
Exploratory Study to Evaluate Uncorrected Distance Vision and Quality of Vision After Light Treatments of an Implanted RxSight Light Adjustable Lens (RXLAL) With The Light Delivery Device (LDD) in Subjects With Preoperative Corneal Astigmatism
The objective of this study is to evaluate uncorrected distance vision and quality of vision as measured by the McAlinden QoV questionnaire 3 months following the final lock-in treatment of the implanted RxSight Light Adjustable…
- Trial name
- NCT03729024
- Testing
- Light Adjustable lens (LAL) and Light Delivery Device (LDD)
- Where
- Mexico
- Volunteers
- 21 people
- Sponsor
- RxSight, Inc.
Aphakia, Cataract
Single Center Exploratory Study To Evaluate The Use Of The RxSight Light Adjustable Lens (LAL) And The Light Delivery Device (LDD) To Improve Visual Outcomes
The objective of this study is to evaluate, for the visual correction of aphakia, whether the RxSight Light Adjustable Lens (LAL) and Light Delivery Device (LDD) can be used to improve visual outcomes after performing adjustments…
- Trial name
- NCT04529616
- Testing
- Light Adjustable lens (LAL) and Light Delivery Device (LDD)
- Where
- Mexico
- Volunteers
- 79 people
- Sponsor
- RxSight, Inc.
Cataract, Corneal Astigmatism
ClarVista HARMONI Toric Trial With Intraoperative Exchange
The purpose of this study was to demonstrate the safety and effectiveness of the HARMONI® Modular Intraocular Lens System with a toric optic in subjects with pre-existing corneal astigmatism in need of cataract surgery.
- Conditions
- Cataract, Corneal Astigmatism, Aphakia
- Trial name
- NCT03054649
- Testing
- HARMONI® Modular Intraocular Lens System, Intraoperative optic exchange
- Where
- 2 sites in Mexico, Philippines
- Volunteers
- 44 people
- Sponsor
- ClarVista Medical
Aphakia
Bicentric Clinical Investigation to Assess Safety and Performance of LuxBoost IOL
The study purpose is to demonstrate safety and performance of bilateral implantation of LuxBoost intraocular lenses compared with the LuxGood Monofocal lens.
- Trial name
- LuxBoost (NCT06258707)
- Testing
- LuxBoost IOL, LuxGood IOL
- Where
- 2 sites in France
- Volunteers
- 58 people
- Sponsor
- Cutting Edge SAS
Aphakia, Presbyopia
Real-World Study of Vivity Intraocular Lenses (IOLs)
The primary objective of this clinical study is to assess the clinical performance of the AcrySof IQ Vivity Extended Vision IOL in a Chinese population.
- Trial name
- NCT04800016
- Testing
- AcrySof IQ Vivity Extended Vision IOL, Cataract surgery
- Where
- China
- Sponsor
- Alcon Research
Aphakia Cataract
Long-Term Clinical Outcomes Of Subjects Enrolled In The RxSight Light Adjustable Lens (LAL) And Light Delivery Device (LDD) New Enrollment Study
This is an observational, follow up study of subjects previously enrolled in the "RxSight Light Adjustable Lens (LAL) and Light Delivery Device (LDD) New Enrollment Study".
- Trial name
- NCT07347379
- Testing
- Light Adjustable lens (LAL) and Light Delivery Device (LDD)
- Where
- 6 sites in United States
- Volunteers
- 108 people
- Sponsor
- RxSight, Inc.
Aphakia, Astigmatism
Evaluation of Long-term Safety and Performance of PanOptix Trifocal Intraocular Lens (IOL)
The purpose of this Post-Market Clinical Follow-up (PMCF) study is to describe the long-term safety and performance of the AcrySof IQ PanOptix IOL toric and non-toric models in subjects bilaterally implanted with these IOLs for 3…
- Conditions
- Aphakia, Astigmatism, Presbyopia
- Trial name
- NCT06166901
- Testing
- AcrySof IQ PanOptix IOL Toric, AcrySof IQ PanOptix IOL Non-Toric
- Where
- 7 sites in Spain
- Volunteers
- 211 people
- Sponsor
- Alcon Research
Normal Non-fluency, Cataract
Comparative Study of the Optical Biometer for Measurements of the Eye
The primary purpose of this comparative clinical study is to collect clinical data to demonstrate the equivalence of the investigational device to the predicate device for measurements of the eye.
- Conditions
- Normal Non-fluency, Cataract, Aphakic Eye, Eyes With Corneal Abnormality
- Trial name
- NCT01729962
- Where
- United States
- Volunteers
- 125 people, healthy volunteers welcome
- Sponsor
- Nidek Co. LTD.
Cataract, Aphakia
Evaluation of the Safety & Effectiveness of the Bausch & Lomb AKREOS® TL Intraocular Lens
This study is to evaluate the safety and effectiveness of the Bausch \& Lomb Akreos TL (thin lens) intraocular lens (IOL) following implantation in adults requiring cataract surgery.
- Trial name
- NCT00838045
- Testing
- The Bausch & Lomb Akreos TL IOL (MI60) posterior chamber IOL
- Where
- Germany
- Volunteers
- 125 people
- Sponsor
- Bausch & Lomb Incorporated
Cataract
Clinical Trial to Evaluate the Model SC9 IOL Compared to the Model LI61SE IOL (Bausch & Lomb)
To evaluate the Model SC9 Intraocular Lens for the improvement of near and intermediate vision when compared to a legally marketed monofocal IOL.
- Trial name
- NCT03179397
- Testing
- Model SC9, Model LI61SE
- Where
- 13 sites in United States
- Volunteers
- 338 people, healthy volunteers welcome
- Sponsor
- CORD, LLC
Aphakia, Cataract
Registry Study on Intraocular Lenses Manufactured by Teleon Surgical B.V.
This is a retrospective, observational (Registry) study aiming to collect safety and performance data on the use of intraocular lenses (IOLs) manufactured by Teleon Surgical B.V. according to routine practice.
- Conditions
- Aphakia, Cataract, Clear Lens Exchange, Refractive Lens Exchange
- Trial name
- NCT05290870
- Testing
- Posterior-chamber intraocular lens
- Where
- Netherlands
- Volunteers
- 2,183 people
- Sponsor
- Teleon Surgical B.V.
Aphakia
Clinical Study of a UV-Absorbing Acrylic Posterior Chamber Intraocular Lens
The purpose of this study is to assess the safety and efficacy of the HMY Model YA-60BB Intraocular Lens (IOL) when implanted in the posterior chamber of the human eye for the optical correction of aphakia following cataract…
- Trial name
- HMY (NCT00625313)
- Testing
- HMY Model YA-60BB IOL
- Where
- United States
- Volunteers
- 617 people, healthy volunteers welcome
- Sponsor
- Hoya Surgical Optics, Inc.
Cataract, Aphakia
A Multi Focal Visual Outcome Study Using Different Near Additions
A multi-centre non-randomized clinical investigation to assess multifocal visual outcomes using different near additions, for the treatment of aphakia after cataract removal.
- Trial name
- NCT00960700
- Testing
- Visual Acuity, Contrast sensitivity, Reading Speed
- Where
- 2 sites in Germany, Lithuania
- Volunteers
- 52 people
- Sponsor
- Rayner Intraocular Lenses Limited
Aphakia, Presbyopia
Clareon PanOptix Pro vs. Clareon PanOptix - Study B
The purpose of this study is to evaluate the safety and effectiveness of Clareon™ PanOptix™ Pro Trifocal Intraocular Lens (IOL) compared to Clareon™ PanOptix™ Trifocal IOL.
- Trial name
- NCT06401551
- Testing
- CPO Pro IOL, CPO IOL, Cataract Surgery
- Where
- 8 sites in United States
- Volunteers
- 71 people
- Sponsor
- Alcon Research
Aphakia, Postcataract
Trial to Investigate the Safety and Effectiveness of the KI-362-US1 (YP2.2VM) Intraocular Lens (IOL) in Adult Participants for Correction of Aphakia Following Cataract Extraction
A study to learn how well an artificial lens, called an intraocular lens (IOL), works in adults who have cataract surgery. During this type of surgery, the eye's natural lens is removed and replaced with an artificial lens to…
- Trial name
- NCT07650201
- Testing
- KI-362-US1 (YP2.2VM)
- Volunteers
- 340 people
- Sponsor
- Kowa Research Institute, Inc.
Aphakia, Cataract
Clinical Evaluation of a Novel Trifocal IOL
The purpose of this study is to understand the visual outcomes of the investigational intraocular lens (IOL) Model LPYWT0 when compared to the commercially marketed Clareon PanOptix Pro IOL Model PXYWT0.
- Trial name
- NCT07587138
- Testing
- LPYWT0, PXYWT0, Cataract Surgery
- Where
- 5 sites in Australia, India and 1 more
- Volunteers
- 66 people
- Sponsor
- Alcon Research
Aphakia, Cataract
Visual Quality Following Aspheric Intraocular Lens (IOL) Implantation - a Comparative Clinical Study
To evaluate visual acuity and quality of vision in participants undergoing cataract surgery with a Hoya model 751 intra-ocular lens and to compare the visual results to the common monofocal lens in use.
- Trial name
- 751 (NCT01544777)
- Testing
- Study IOL, Hoya iSert 751, Negatively aspheric IOL
- Where
- Australia
- Volunteers
- 42 people
- Sponsor
- Hoya Surgical Optics, Inc.
Aphakia
Clinical Evaluation of the FluidVision Accommodating Intraocular Lens (AIOL)
The purpose of this study is to evaluate the safety and effectiveness of an investigational IOL.
- Trial name
- NCT02049567
- Testing
- FluidVision AIOL, Cataract Surgery
- Where
- 8 sites in Germany, South Africa
- Volunteers
- 170 people
- Sponsor
- PowerVision
Aphakia, Corneal Astigmatism
Clinical Investigation of an AcrySof IQ PanOptix Toric Intraocular Lens
The purpose of this study is to evaluate the effectiveness and safety of the TFNT20 low cylinder power intraocular lens when implanted in the eye to replace the natural lens following cataract removal.
- Trial name
- NCT04542525
- Testing
- ACRYSOF IQ PanOptix Toric Trifocal IOL, Cataract surgery
- Where
- Japan
- Volunteers
- 32 people
- Sponsor
- Alcon Research