Clinical trials: Aphakic Eye
Cataract
PMCF Study of Preloaded Trifocal IOL
This is a study to evaluate the safety, effectiveness and patient satisfaction of the Trifocal Intraocular Lens after implanted to replace the natural lens following cataract removal.
- Trial name
- NCT04884178
- Testing
- Trifocal Preloaded IOL Delivery System
- Where
- Taiwan
- Volunteers
- 25 people
- Sponsor
- ICARES Medicus, Inc.
Aphakia
Clinical Evaluation of the FluidVision Accommodating Intraocular Lens (AIOL)
The purpose of this study is to evaluate the safety and effectiveness of an investigational IOL.
- Trial name
- NCT02049567
- Testing
- FluidVision AIOL, Cataract Surgery
- Where
- 8 sites in Germany, South Africa
- Volunteers
- 170 people
- Sponsor
- PowerVision
Aphakia, Cataract
A Clinical Study to Evaluate The Safety and Effectiveness of The RxSight Light Adjustable Lens (LAL) In Subjects Desiring an Extended Depth of Focus
The primary objective of this study is to evaluate, for the visual correction of aphakia and presbyopia, the safety and effectiveness of the RxSight Light Adjustable Lens (LAL) to provide an extended depth of focus (improve…
- Conditions
- Aphakia, Cataract, Presbyopia
- Trial name
- NCT04177771
- Testing
- Light Adjustable lens (LAL) and Light Delivery Device (LDD) - Pre-COVID Population, SofPort LI61AO IOL, Tecnis ZCB00 or ZTC150 IOL
- Where
- United States
- Volunteers
- 34 people
- Sponsor
- RxSight, Inc.
Cataract
Safety and Efficacy of the Bi-Aspheric Monofocal IOL
This is an observational, single-center, non-control, open-label post-marketing study. Patients implanted with an aspicio™ Monofocal Intraocular Lens will be scheduled for a follow-up visit at least 3 months after the surgery to…
- Trial name
- NCT06380478
- Testing
- aspicio Monofocal IOL
- Where
- Taiwan
- Volunteers
- 30 people
- Sponsor
- ICARES Medicus, Inc.
Aphakia
Clinical Study of a UV-Absorbing Acrylic Posterior Chamber Intraocular Lens
The purpose of this study is to assess the safety and efficacy of the HMY Model YA-60BB Intraocular Lens (IOL) when implanted in the posterior chamber of the human eye for the optical correction of aphakia following cataract…
- Trial name
- HMY (NCT00625313)
- Testing
- HMY Model YA-60BB IOL
- Where
- United States
- Volunteers
- 617 people, healthy volunteers welcome
- Sponsor
- Hoya Surgical Optics, Inc.
Aphakia
A Real-World Evidence (RWE) Long-Term Follow-Up Study to Assess Outcomes of Alcon Monofocal Intraocular Lenses
The purpose of this post-market clinical follow-up (PMCF) study is to describe the long-term safety and performance of AcrySof Single-Piece and AcrySof Multi-Piece monofocal intraocular lenses (IOLs).
- Trial name
- NCT05799950
- Testing
- AcrySof single-piece IOL, AcrySof multi-piece IOL
- Where
- 7 sites in United States, Puerto Rico
- Volunteers
- 138 people
- Sponsor
- Alcon Research
Cataract
A Study Assessing Safety and Efficacy of MD-15 Intraocular Lens in Patients With Aphakic Eye After Cataract Surgery
To evaluate safety and efficacy of MD-15 intraocular lens implanted into the aphakic eyes
- Trial name
- NCT02888210
- Testing
- MD-15 Intraocular Lens
- Where
- Japan
- Volunteers
- 110 people
- Sponsor
- Santen Pharmaceutical Co., Ltd.
Aphakia
Feasibility Study of an Accommodating IOL Design
The purpose of this clinical study is to assess safety and explore usability and effectiveness of the test product, AAL-FAIOL. This study will be conducted in Central America.
- Trial name
- NCT07147192
- Testing
- AAL-FAIOL, BAL-FAIOL, Phacoemulsification
- Where
- 4 sites in Costa Rica, Dominican Republic and 2 more
- Volunteers
- 17 people
- Sponsor
- Alcon Research
Aphakia, Presbyopia
Clareon PanOptix Pro vs. Clareon PanOptix - Study A
The purpose of this study is to evaluate the safety and effectiveness of Clareon™ PanOptix™ Pro Trifocal Intraocular Lens (IOL) compared to Clareon™ PanOptix™ Trifocal IOL.
- Trial name
- NCT06400745
- Testing
- CPO Pro IOL, CPO IOL, Cataract surgery
- Where
- 8 sites in United States
- Volunteers
- 87 people
- Sponsor
- Alcon Research
Cataract, Aphakia
Clareon Toric vs Eyhance Toric
The primary purpose of this study is to compare the Clareon/Clareon Toric Intraocular Lenses (IOLs) to the Eyhance/Eyhance Toric IOLs in binocular Best Corrected Distance Visual Acuity (BCDVA) at 3 months postoperative.
- Trial name
- NCT05481125
- Testing
- Clareon IOL, Clareon Toric IOL, Eyhance IOL
- Where
- 8 sites in United States
- Volunteers
- 203 people
- Sponsor
- Alcon Research
Aphakia, Corneal Astigmatism
Clinical Investigation of an AcrySof IQ PanOptix Toric Intraocular Lens
The purpose of this study is to evaluate the effectiveness and safety of the TFNT20 low cylinder power intraocular lens when implanted in the eye to replace the natural lens following cataract removal.
- Trial name
- NCT04542525
- Testing
- ACRYSOF IQ PanOptix Toric Trifocal IOL, Cataract surgery
- Where
- Japan
- Volunteers
- 32 people
- Sponsor
- Alcon Research
Normal Non-fluency, Cataract
Comparative Study of the Optical Biometer for Measurements of the Eye
The primary purpose of this comparative clinical study is to collect clinical data to demonstrate the equivalence of the investigational device to the predicate device for measurements of the eye.
- Conditions
- Normal Non-fluency, Cataract, Aphakic Eye, Eyes With Corneal Abnormality
- Trial name
- NCT01729962
- Where
- United States
- Volunteers
- 125 people, healthy volunteers welcome
- Sponsor
- Nidek Co. LTD.
Cataract
Post-Implant Performance of the EC-3 IOL
The purpose of this study is to obtain data on the performance of the EC-3 lens at an interval of two years (and beyond) from subjects who were implanted.
- Trial name
- NCT01333345
- Where
- 3 sites in United States, France
- Volunteers
- 100 people
- Sponsor
- Aaren Scientific Inc.
Cataract, Aphakia
A Multi Focal Visual Outcome Study Using Different Near Additions
A multi-centre non-randomized clinical investigation to assess multifocal visual outcomes using different near additions, for the treatment of aphakia after cataract removal.
- Trial name
- NCT00960700
- Testing
- Visual Acuity, Contrast sensitivity, Reading Speed
- Where
- 2 sites in Germany, Lithuania
- Volunteers
- 52 people
- Sponsor
- Rayner Intraocular Lenses Limited
Cataract
A Clinical Investigation of the ClarVista HARMONI™ Modular Intraocular Lens Implant Following Cataract Surgery
The main objectives of this feasibility study were: To demonstrate the feasibility of HARMONI Modular Intraocular Lens (HMIOL) implantation and assembly in subjects undergoing cataract surgery (All HMIOL Cohort), and To…
- Trial name
- NCT02521766
- Testing
- Harmoni Modular Intraocular Lens, Commercially Available Intraocular Lens, Optic exchange
- Where
- 2 sites in New Zealand, Philippines
- Volunteers
- 217 people
- Sponsor
- ClarVista Medical
Aphakia, Cataract
Exploratory Study to Evaluate Uncorrected Distance Vision and Quality of Vision After Light Treatments of an Implanted RxSight Light Adjustable Lens (RXLAL) With The Light Delivery Device (LDD) in Subjects With Preoperative Corneal Astigmatism
The objective of this study is to evaluate uncorrected distance vision and quality of vision as measured by the McAlinden QoV questionnaire 3 months following the final lock-in treatment of the implanted RxSight Light Adjustable…
- Trial name
- NCT03729024
- Testing
- Light Adjustable lens (LAL) and Light Delivery Device (LDD)
- Where
- Mexico
- Volunteers
- 21 people
- Sponsor
- RxSight, Inc.
Aphakia
Evaluation of Clareon Vivity/Vivity Toric
This study seeks to generate clinical data from subjects previously implanted with the Clareon Vivity/Vivity Toric Intraocular Lenses (IOLs) or Clareon Monofocal/Clareon Toric IOLs.
- Trial name
- NCT05852470
- Testing
- Clareon Vivity/Vivity Toric Extended Vision IOL, Clareon Monofocal/Clareon Toric IOL
- Where
- 7 sites in United States
- Volunteers
- 155 people
- Sponsor
- Alcon Research
Aphakia
Clinical Evaluation of the Lenstec Softec HP1 Intraocular Lens
The study is designed as a post market evaluation of the Softec HP1 IOL for continuance of the CE certificate. The primary effectiveness endpoint is to evaluate the safety and performance levels produced by this IOL in patients…
- Trial name
- NCT03900260
- Testing
- Softec HP1 Intraocular Lens
- Where
- 3 sites in United Kingdom
- Volunteers
- 87 people, healthy volunteers welcome
- Sponsor
- Lenstec Incorporated
Aphakia, Postcataract
Trial to Investigate the Safety and Effectiveness of the KI-362-US1 (YP2.2VM) Intraocular Lens (IOL) in Adult Participants for Correction of Aphakia Following Cataract Extraction
A study to learn how well an artificial lens, called an intraocular lens (IOL), works in adults who have cataract surgery. During this type of surgery, the eye's natural lens is removed and replaced with an artificial lens to…
- Trial name
- NCT07650201
- Testing
- KI-362-US1 (YP2.2VM)
- Volunteers
- 340 people
- Sponsor
- Kowa Research Institute, Inc.
Aphakia
Evaluation of the FluidVision Accommodating Intraocular Lens (AIOL) With an Improved Injector System
The purpose of this study is to evaluate the clinical outcomes of an investigational IOL in patients undergoing cataract extraction and intraocular lens implantation using an improved injector system.
- Trial name
- NCT02418871
- Testing
- FluidVision AIOL, Cataract surgery
- Where
- 5 sites in Hungary, South Africa
- Volunteers
- 53 people
- Sponsor
- PowerVision