Clinical trials: Apnea, Sleep
Obstructive Sleep Apnea
Comparison Study of the ICON™ CPAP Series With and Without SensAwake™
Conceptually, awareness of pressure occurs only during wakefulness. Thus reducing the pressure during wakefulness may improve therapy comfort and potentially adherence without compromizing therapy efficacy.
- Trial name
- NCT01831258
- Testing
- SensAwake On, SensAwake Off
- Where
- 3 sites in United States
- Volunteers
- 70 people
- Sponsor
- Fisher and Paykel Healthcare
Sleep Apnea
Phenotypic Characteristics of Responders to Obstructive Sleep Apnea Treatment Using Mandibular Advancement Devices
Currently, mandibular advancement devices (MAD) are recommended by the American Academy of Sleep Medicine (AASM) as the first treatment a line in cases of mild and moderate OSAS in patients without severe cardiovascular…
- Trial name
- NCT05596825
- Testing
- Mandibular Advancement Device
- Volunteers
- 75 people
- Sponsor
- University of Valencia
Asthma, Obstructive Sleep Apnea Syndrome
CPASMA: Is There an Improvement in Asthma in Patients With Both Asthma and OSAS Treated With CPAP?
The CPASMA trial is a descriptive, prospective, multicentre clinical trial, with a before/after Continuous Positive Airway Pressure (CPAP) assessment in participating patients.
- Trial name
- CPASMA (NCT01374932)
- Testing
- CPAP
- Where
- 10 sites in Spain
- Volunteers
- 120 people
- Sponsor
- Cimera
Childhood Obesity, Sleep Apnea in Obese Children
Play as a Method to Reduce Overweight and Obesity in Children.
Introduction Overweight and obesity are characterised by excess fat, which results in weight gain and is identified by the Body Mass Index (BMI).
- Conditions
- Childhood Obesity, Sleep Apnea in Obese Children, Studying Maternal and Family Factors That Cause Obesity in Children
- Trial name
- Kids-Play (NCT02779647)
- Testing
- The intervention consisted of physical activity based on play
- Volunteers
- 98 people, healthy volunteers welcome
- Sponsor
- Universidad de Granada
Diabetes Mellitus, Periodontal Diseases
Periodontitis as Signal for an Underlying Disease
This study investigates the differences between subjects with and without periodontitis in: the prevalence of (pre)diabetes mellitus, the risk of atherosclerotic cardiovascular disease, the prevalence of metabolic syndrome and…
- Conditions
- Diabetes Mellitus, Periodontal Diseases, Cardiovascular Diseases, Obstructive Sleep Apnea Syndrome
- Trial name
- PACMEL (NCT03459638)
- Testing
- Screening for DM, ASCVD, MetS and OSAS
- Where
- Netherlands
- Volunteers
- 105 people, healthy volunteers welcome
- Sponsor
- Academic Centre for Dentistry in Amsterdam
Sleep Apnea, Metabolic Syndrome
Improving the STOP-Bang Screening Questionnaire for Patients With Sleep Apnea
The study is being conducted to test the ability of a simple questionnaire to detect mild, moderate or severe obstructive sleep apnea.
- Trial name
- NCT01610648
- Where
- United States
- Volunteers
- 258 people
- Sponsor
- Tufts Medical Center
Obstructive Sleep Apnea
Validation of Safety and Efficacy for Night Shift Therapy
The purpose of this study is to assess the accuracy of Night Shift in the detection of supine sleep and efficacy of vibro-tactile feedback in restricting supine sleep.
- Trial name
- NCT02032706
- Testing
- Deliver therapy when the supine position is detected
- Where
- United States
- Volunteers
- 36 people
- Sponsor
- Advanced Brain Monitoring, Inc.
Sleep Apnea Syndromes, Venous Thromboembolism
Sleep Apnea and Tromboembolic Disease
There is some evidence for a hypercoagulable state in sleep apnea-hipopnea syndrome (SAHS), which could play a role in the increased cardiovascular morbility and mortality.
- Trial name
- NCT00501358
- Where
- Spain
- Sponsor
- Sociedad Española de Neumología y Cirugía Torácica
Sleep, Sleep Apnea
Research Framework Exploring Sleep Health
This is a digital health study in which participants are recruited to collect sleep and activity data from digital activity trackers.
- Conditions
- Sleep, Sleep Apnea, Obesity, Mood
- Trial name
- REFRESH (NCT05197738)
- Where
- United States
- Volunteers
- 100,000 people, healthy volunteers welcome
- Sponsor
- Scripps Translational Science Institute
Sleep Apnea, Obstructive
eXciteOSA for Treatment of Moderate Obstructive Sleep Apnea
The objective of this study is to assess the efficacy of the eXciteOSA device amongst a sample of patients with moderate OSA. The study is a multi-center, prospective, open-label, randomized, parallel-arm trial of eXciteOSA…
- Trial name
- ELMO (NCT05252156)
- Testing
- eXciteOSA
- Where
- 7 sites in United States
- Volunteers
- 62 people
- Sponsor
- Signifier Medical Technologies
Sleep Apnea Syndrome, Obstructive, Drowsiness
Ocular Parameters in Patients With Sleep Apnea
The aim of this study is to assess the ocular parameters of drowsiness in patients with diagnosed Obstructive Sleep Apnea Syndrome through objective methods of ocular imaging and subjective evaluation methods (questionnaire)
- Conditions
- Sleep Apnea Syndrome, Obstructive, Drowsiness, Blinking, Concentration Ability Impaired
- Trial name
- NCT05911737
- Testing
- Short video and Questionnaire
- Where
- Greece
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Democritus University of Thrace
Obstructive Sleep Apnea
The Treatment of Obstructive Sleep Apnea With Continuous Positive Airway Pressure on Appearance and Age
The investigators hypothesized that the treatment of obstructive sleep apnea (OSA) with continuous positive airway pressure (CPAP) will positively affect the appearance of the patient.
- Trial name
- NCT02117271
- Testing
- continuous positive airway pressure, Breathe Right ®
- Where
- Brazil
- Volunteers
- 30 people
- Sponsor
- Nucleo Interdisciplinar da Ciencia do Sono
Apnea, Sleep
Remifentanil in Adults With OSA
Obstructive Sleep Apnea (OSA) is the most common problem that affects sleep. People with this problem have their airway blocked or minimized, causing snoring or gasping while sleeping.
- Trial name
- AROSA (NCT02898792)
- Testing
- Targeted infusion of remifentanil
- Where
- United States
- Volunteers
- 77 people, healthy volunteers welcome
- Sponsor
- Washington University School of Medicine
Sleep Apnea, Snoring
Study to Determine Results of Vibratory Stimulus on Subject's Neck
This study will validate whether an external vibratory stimulus applied to a subject's neck causes head, neck or jaw movement.
- Trial name
- NCT01491828
- Testing
- Kai Strap
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Kai Medical, Inc.
Obesity, Obstructive Sleep Apnea
Does Treating Obstructive Sleep Apnea in Obese Canadian Youth Improve Blood Sugar Control?
To determine whether, in obese children with moderate-severe Obstructive Sleep Apnea who are prescribed Positive Airway Pressure(PAP) therapy, increased hours of PAP usage per night over a one-year period is associated with a…
- Trial name
- IMPACT Obesity (NCT01116375)
- Where
- 4 sites in Canada
- Volunteers
- 27 people
- Sponsor
- Katz, Sherri Lynne, M.D.
Acute Ischemic Stroke, Sleep Apnea
Continuous Positive Airway Pressure for the Treatment of Stroke
New stroke therapies are needed. This study seeks to provide the preliminary data needed to plan a future study that will evaluate the efficacy of using continuous positive airway pressure (CPAP) to treat stroke patients who have…
- Trial name
- NCT00368628
- Testing
- continuous positive airway pressure
- Where
- United States
- Volunteers
- 55 people
- Sponsor
- Yale University
Obstructive Sleep Apnea
In-Hospital Portable Sleep Monitoring for the Evaluation of Obstructive Sleep Apnea (OSA)
Hypothesis: Portable sleep testing of hospitalized medical inpatients suspected of having OSA is accurate in determining the need for positive airway pressure (PAP) therapy when compared to outpatient laboratory-based…
- Trial name
- NCT01424592
- Testing
- Testing with a portable sleep apnea monitor .
- Where
- United States
- Volunteers
- 140 people
- Sponsor
- Cook County Health
Obstructive Sleep Apnea
Bioburden and Usability Evaluation of a Nasal Prototype CPAP Mask
AIM AND HYPOTHESIS: The purpose of this study is to monitor the bioburden and impedance characteristics of a prototype mask system and to evaluate the usability of the mask system.
- Trial name
- NCT02255539
- Testing
- Geelong Prototype Mask
- Where
- Australia
- Volunteers
- 42 people
- Sponsor
- ResMed
Obstructive Sleep Apnea
Circadian Intraocular Pressure Patterns in Patients With Sleep Apnea Syndrome and Treatment With Continuous Air Pressure
The purpose of this study is to evaluate the influence of sleep apnea-hypopnea syndrome (SAHS) syndrome and treatment with continuous air pressure (CPAP) on the circadian intraocular pressure (IOP) patterns and its structural…
- Trial name
- NCT06152692
- Testing
- Continuous positive airway pressure
- Where
- Spain
- Volunteers
- 111 people
- Sponsor
- Sociedad Española de Neumología y Cirugía Torácica
Obesity, Obstructive Sleep Apnea Syndrome
Pilot Study to Assess the Effectiveness of Tonsil and Adenoidectomy (T+A) in Overweight Children and Adolescents
Obesity has reached epidemic proportions in the United States with roughly 20% of American children being overweight and has serious consequences such as sleep apnea.Additionally, obesity is known to result in the earlier onset…
- Trial name
- NCT00222963
- Where
- United States
- Volunteers
- 250 people
- Sponsor
- University of Rochester