Clinical trials: Apnea, Sleep
Sleep Disorders
Effect of High Rebound Mattress Toppers on Sleep and Sleep-Related Symptoms
The purpose of the study is to evaluate effects of high rebound mattress toppers (i.e., airweave®) on sleep and sleep-related symptoms.
- Trial name
- NCT03055156
- Testing
- Low rebound mattress toppers, High rebound mattress toppers
- Where
- United States
- Volunteers
- 558 people
- Sponsor
- Stanford University
Obstructive Sleep Apnea
Nexus Compliance Study
Obstructive sleep apnoea (OSA) is characterised by a partial or complete collapse of the upper airway during sleep. The treatment of choice for OSA is Continuous Positive Airway Pressure (CPAP).
- Trial name
- NCT01013207
- Testing
- CPAP Pre Nexus (S9), Nexus (S9), CPAP Post Nexus (S9)
- Where
- Australia
- Volunteers
- 50 people
- Sponsor
- ResMed
Obstructive Sleep Apnea of Adult
ANNE Diagnostic Agreement With Home Sleep Testing
The main objective of this study is to provide an adequately powered study that would provide evidence on the non-inferiority of ANNE to a Home Sleep Test (HST).
- Trial name
- NCT05421754
- Testing
- ANNE Sleep
- Where
- United States
- Volunteers
- 38 people
- Sponsor
- Northwestern University
Sleep Apnea, Central Sleep Disordered Breathing
The remedē® System for the Treatment of Central Sleep Apnea in Daily Practice
The aim of this post market study is to assess the impact of sleep-disordered breathing on the well-being of patients according to the treatment chosen, i.e.
- Trial name
- TREAT-CSA (NCT02577445)
- Where
- 10 sites in Germany, Spain
- Volunteers
- 31 people
- Sponsor
- LivaNova
Mask Ventilation, Airway Obstruction Upper
The Articulated Oral Airway as an Aid to Mask Ventilation
The Articulating Oral Airway (AOA) is a novel oral airway which actively displaces the tongue, allowing for a greater cross-sectional area for mask ventilation.
- Conditions
- Mask Ventilation, Airway Obstruction Upper, Airway Management
- Trial name
- NCT03144089
- Testing
- Articulated Oral Airway, Guedel oral airway (active comparator)
- Where
- United States
- Volunteers
- 58 people, healthy volunteers welcome
- Sponsor
- Ron Abrons
Obstructive Sleep Apnea
Belun Ring Validation Study for Assessment of Obstructive Sleep Apnea
This study aims to determine the overall accuracy, sensitivity, and specificity of the Belun Ring device in evaluating obstructive sleep apnea by comparing the device to the attended overnight in-lab polysomnography which is the…
- Trial name
- NCT03997916
- Testing
- Belun Ring, PSG
- Where
- 2 sites in United States
- Volunteers
- 113 people, healthy volunteers welcome
- Sponsor
- University Hospitals Cleveland Medical Center
Polycystic Ovary Syndrome (PCOS), Obstructive Sleep Apnea
Sex Steroids, Sleep, and Metabolic Dysfunction in Women
Increased plasma triglyceride concentration is a common feature of the metabolic abnormalities associated with obesity and a major risk factor for cardiovascular disease.
- Conditions
- Polycystic Ovary Syndrome (PCOS), Obstructive Sleep Apnea, Obesity
- Trial name
- SCOR (NCT00805207)
- Testing
- Progesterone, testosterone, glucocorticoid
- Where
- United States
- Volunteers
- 61 people, healthy volunteers welcome
- Sponsor
- Washington University School of Medicine
Perennial Allergic Rhinitis, Obstructive Sleep Apnea
The Effects of Mometasone Furoate Nasal Spray in Subjects With Sleep-disordered Breathing (SDB) Associated With Perennial Allergic Rhinitis (Study P04726)
This is a Phase 4 randomized, placebo-controlled, parallel-group, single-center, double-blind study to evaluate the effects of mometasone furoate nasal spray (MFNS) in subjects with Sleep-disordered Breathing (SDB) associated…
- Conditions
- Perennial Allergic Rhinitis, Obstructive Sleep Apnea, Sleep Disorder
- Trial name
- NCT00359216
- Testing
- Mometasone furoate nasal spray
- Volunteers
- 30 people
- Sponsor
- Organon and Co
Sleep-Disordered Breathing
Pediatric Adenotonsillectomy Trial for Snoring
The purpose of this study is to evaluate the effects of early adenotonsillectomy (eAT) on the behavior, sleep-disordered breathing symptoms and quality of life for children who snore, but do not have obstructive sleep apnea, as…
- Trial name
- PATS (NCT02562040)
- Testing
- Early Adenotonsillectomy (eAT), Watchful Waiting with Supportive Care (WWSC)
- Where
- 7 sites in United States
- Volunteers
- 459 people
- Sponsor
- Brigham and Women's Hospital
Sleep Apnea, Sleep-Disordered Breathing
Alice PDx User/Validation Extended Trial
The objective of this study is to test the usability of the Alice PDx device by both the end user (patient/participant) and the sleep technician.
- Trial name
- NCT00841906
- Testing
- Alice PDx with only written instructions, Alice PDx with written and verbal instructions
- Where
- 2 sites in United States
- Volunteers
- 32 people
- Sponsor
- Philips Respironics
Obesity
BLOOM-DM: Behavioral Modification and Lorcaserin for Overweight and Obesity Management in Diabetes Mellitus
The purpose of this study is to assess the weight loss effect of lorcaserin during and at the end of 1 year of treatment in overweight and obese patients with Type II diabetes mellitus treated with metformin, sulfonylurea (SFU)…
- Trial name
- NCT00603291
- Testing
- Lorcaserin 10 mg once daily (QD), Lorcaserin 10 mg twice a day (BID)
- Where
- United States
- Volunteers
- 604 people
- Sponsor
- Eisai Inc.
Spinal Cord Injury, Sleep Apnea, Obstructive
Sleep-Disordered Breathing in Chronic SCI
The purpose of this study is to examine impact of Sleep Disordered Breathing (SDB) treatment in persons with chronic Spinal Cord Injury (SCI).
- Trial name
- NCT02176928
- Testing
- AutoPAP
- Where
- 4 sites in United States
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- University of Miami
Chronic Obstructive Pulmonary Disease (COPD), Congestive Heart Failure (CHF)
Clinical Trials for Elderly Patients With Multiple Disease
The CHROMED project focuses its investigation on the applicability of an integrated solution for a pathological condition which: a) is very prevalent in ageing patients and b) severely impairs quality of life: COPD with other…
- Conditions
- Chronic Obstructive Pulmonary Disease (COPD), Congestive Heart Failure (CHF), Sleep Disordered Breathing (SDB)
- Trial name
- CHROMED (NCT01960907)
- Testing
- CHROMED monitoring system
- Where
- 6 sites in Estonia, Slovenia and 3 more
- Volunteers
- 312 people
- Sponsor
- Restech Srl
OSA
Parallel-Arm Study to Compare AD109 to Placebo With Patients With OSA (SynAIRgy Study)
This is a Phase 3 Randomized Double-Blind Placebo-Controlled 6-month Parallel-Arm Study to Compare a Fixed Dose Combination of AD109 to Placebo in Obstructive Sleep Apnea.
- Trial name
- NCT05813275
- Testing
- AD109
- Where
- 73 sites in United States, Canada
- Volunteers
- 646 people
- Sponsor
- Apnimed
Obstructive Sleep Apnea (OSA)
Correlation Endoscopic View of Airway Obstruction With RRa in OSA Patients Under DEX Monitored With SedLine EEG
Patients with obstructive sleep apnea (OSA) could have several anatomical causes of obstruction. A sleep endoscopy study is a technique to help determine the anatomical cause of OSA.
- Trial name
- NCT02639884
- Testing
- SedLine EEG, RRa monitoring
- Where
- United States
- Volunteers
- 51 people
- Sponsor
- Masimo Corporation
Interstitial Lung Disease, Obstructive Sleep Apnea
Assessment of Continuous Positive Airway Pressure Therapy in OSA and ILD
The purpose of this study is to evaluate whether biomarkers of lung epithelial and endothelial injury are associated with obstructive sleep apnea (OSA) and interstitial lung disease (ILD).
- Trial name
- NCT03901534
- Testing
- Continuous positive airway pressure (CPAP) therapy, Nox A1 Recorder
- Where
- 2 sites in United States
- Volunteers
- 2,021 people
- Sponsor
- Columbia University
Excessive Sleepiness
Study to Evaluate Armodafinil Treatment in Improving Prefrontal Cortical Activation and Working Memory Performance
The primary objective of this study is to determine whether treatment with armodafinil will provide improvements in prefrontal cortical activation in patients with OSAHS (Obstructive Sleep Apnea/Hypopnea Syndrome) who have…
- Trial name
- NCT00711516
- Testing
- Armodafinil
- Where
- 9 sites in United States
- Volunteers
- 40 people
- Sponsor
- Cephalon
Obstructive Sleep Apnea, Sleep Hypopnea
Armodafinil (CEP-10953) in Treatment of Excessive Sleepiness Associated With Obstructive Sleep Apnea/Hypopnea (OSA/H) Syndrome
The primary objective of this study is to determine whether treatment with Armodafinil (CEP-10953) is more effective than placebo treatment for patients with residual excessive sleepiness associated with obstructive sleep…
- Trial name
- NCT00079677
- Testing
- Armodafinil 150 mg/day
- Volunteers
- 263 people
- Sponsor
- Cephalon
Obstructive Sleep Apnea
Trial of AD036 in Obstructive Sleep Apnea
This is a randomized, double blind, placebo-controlled, repeat-dose, parallel arm, outpatient and inpatient phase 2 clinical study to examine the efficacy and safety of three dose levels of AD036 versus placebo in patients with…
- Trial name
- NCT03845023
- Testing
- AD036 Dose 1, AD036 Dose 2, AD036 Dose 3
- Where
- 12 sites in United States
- Volunteers
- 140 people
- Sponsor
- Apnimed
Sleep Apnea, Obstructive, Delirium
Effect of CPAP on Postoperative Delirium
Patients with a medical condition known as obstructive sleep apnea may be at increased risk of delirium following surgery. This study loans autotitrating CPAP machines to randomly-selected patients who are at high-risk for…
- Trial name
- NCT01816685
- Testing
- CPAP
- Where
- United States
- Volunteers
- 135 people
- Sponsor
- Duke University