Clinical trials: Apnoea
Obstructive Sleep Apnea (OSA)
Effects of Audiovisual Distraction on Desaturation and Airway Intervention in OSA-patients
Patients will be randomly assigned to either one of two groups: 1. Standard of care sedation 2. Audiovisual distraction during surgery and in the recovery room using video goggles and headphones; patients can choose a movie from…
- Trial name
- AVD (NCT03020914)
- Testing
- Audiovisual Distraction
- Volunteers
- 19 people, healthy volunteers welcome
- Sponsor
- Hospital for Special Surgery, New York
Hypertension, Blood Pressure
Feasibility and Effectiveness of a Ring-type Blood Pressure Measurement Device
The goal of this clinical trial is to evaluate the feasibility and effectiveness of a ring-type blood pressure measurement device compared to a 24-hour ambulatory blood pressure monitoring device in patients with hypertension or…
- Conditions
- Hypertension, Blood Pressure, Systolic Hypertension, Diastolic Hypertension
- Trial name
- NCT06084065
- Testing
- CART-I Plus
- Where
- South Korea
- Volunteers
- 40 people
- Sponsor
- Seoul National University Hospital
Obstructive Sleep Apnea
Spinal Morphine for Patients With Obstructive Sleep Apnea
Patients with Obstructive Sleep Apnea (OSA) appear to be especially vulnerable to medications that suppress pharyngeal muscle activity such as general anesthetics and opioids.
- Trial name
- NCT01790971
- Testing
- Intrathecal Morphine, No Intrathecal Morphine
- Where
- Canada
- Volunteers
- 40 people
- Sponsor
- University Health Network, Toronto
Obstructive Sleep Apnea
Alesis OSA-1 Obstructive Sleep Apnea Treatment
The goal of randomized clinical trial is to determine if the Alesis OSA-1 low laser light therapy device can reduce apnea-hypopnea index scores and treat sleep apnea in adult participants over the age of 18 who are diagnosed with…
- Trial name
- OSA (NCT06949969)
- Testing
- OSA LLLT treatment device
- Where
- 2 sites in United States
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- Photonica USA, LLC
Postpoliomyelitis Syndrome
Modafinil to Treat Fatigue in Post-Polio Syndrome
This study, conducted at the Walter Reed Army Medical Center, the National Rehabilitation Hospital, and the National Institutes of Health, will examine whether the drug Modafinil can decrease fatigue in patients with post-polio…
- Trial name
- NCT00067496
- Testing
- Modafinil
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- National Institute of Neurological Disorders and Stroke (NINDS)
Acute Coronary Syndrome
Central Apnea in Patients Receiving Ticagrelor
all patients with a left ventricular ejection fraction superior or equal to 50% less than 2 years after an acute coronary event and receiving ticagrelor will undergo a sleep polygraphy
- Trial name
- NCT03540459
- Testing
- sleep polygraphy
- Where
- France
- Volunteers
- 50 people
- Sponsor
- Les Grands Prés
Adenotonsillar Hypertrophy, Tonsillitis
Comparison of Floseal Hemostasis Tonsillectomy With Coblation Tonsillectomy and Cautery Hemostasis Tonsillectomy
The purpose of this study is to evaluate a new method of hemostasis, floseal gel, in tonsillectomy and adenoidectomy, with the goal of decreasing post operative and intraoperative morbidity.
- Conditions
- Adenotonsillar Hypertrophy, Tonsillitis, Obstructive Sleep Apnea
- Trial name
- NCT00459927
- Testing
- Floseal tonsillectomy, Coblation tonsillectomy
- Volunteers
- healthy volunteers welcome
- Sponsor
- Kaiser Permanente
Sleep Apnea, Allergic Rhinitis
Impact of Pollution on Allergic Rhinitis and Sleep Quality: the POLLAR Study
It has been demonstrated that allergic rhinitis (AR) reduces sleep quality by some components such as nasal obstruction. Pollution and allergen exposure worsening AR, sleep quality is deteriorated.
- Conditions
- Sleep Apnea, Allergic Rhinitis, Allergic Asthma, Pollution Exposure
- Trial name
- POLLAR (NCT03776773)
- Testing
- Pollution exposure
- Where
- France
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- University Hospital, Grenoble
Obstructed Sleep Apnea Syndrome in Patient Candidate to Baratric Surgery
Ketogenic Diet and CPAP Previous Bariatric Surgery
Obstructive Sleep Apnea Syndrome (OSAS) and obesity tend to coexist and are often associated with arterial hypertension, dyslipidaemia, and insulin resistance [1].
- Trial name
- NCT03791242
- Testing
- Cpap and ketogenic diet
- Where
- Italy
- Volunteers
- 66 people
- Sponsor
- University of Roma La Sapienza
Chronic Respiratory Failure
Database of Patients Treated With Respiratory Support
An observatory of patients registered in 22 local homecare associations in France, for respiratory diseases, with annual data update.
- Trial name
- observatory (NCT01181869)
- Testing
- oxygen
- Where
- France
- Volunteers
- 120,000 people
- Sponsor
- Association Nationale pour les Traitements A Domicile, les Innovations et la Recherche
Sleep Apnea Syndromes
Multicenter Study on the Role of Neurodegeneration Biomarkers in Obstructive Sleep Apnea Syndrome With Residual Excessive Daytime Sleepiness.
Excessive daytime sleepiness which still remains after an effective treatment with nocturnal ventilotherapy or with other specific treatments (positional therapy, oro-mandibular devices) in patients with obstructive sleep apnea…
- Trial name
- EDS in OSA (NCT05795270)
- Testing
- Treatment
- Where
- Italy
- Volunteers
- 100 people
- Sponsor
- Istituto Auxologico Italiano
Obstructive Sleep Apnea, Obstructive Sleep Apnea (OSA)
EURO-STIM Registry
The registry is to measure longitudinal outcomes and adherence of the Inspire System. The goal of the registry is to capture the life cycle of the patient's use of the Inspire System through routine clinical care visits.
- Trial name
- EURO-STIM (NCT06971796)
- Testing
- Inspire UAS System
- Where
- 21 sites in Austria, Belgium and 5 more
- Volunteers
- 1,000 people
- Sponsor
- Inspire Medical Systems, Inc.
Spinal Cord Injury, Sleep Disordered Breathing
Role of Enhancing Serotonin Receptors Activity for Sleep Apnea Treatment in Patients With SCI
The purpose of this study is to look at the effect of exciting using drugs to target a specific pathway in the body, that relies on a natural chemical the body produces called 'serotonin', in patients with spinal cord injury…
- Trial name
- REST-SCI (NCT02458469)
- Testing
- Buspirone, Trazodone
- Where
- United States
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- VA Office of Research and Development
Obstructive Sleep Apnea
Asthma Outcomes in Children After Adenotonsillectomy
The aim of the study is to assess the effect of adenotonsillectomy on level of asthma control in preschool children with obstructive sleep apnea.
- Trial name
- NCT03842618
- Volunteers
- 60 people
- Sponsor
- Assiut University
Sleep Apnea Syndrome, Obstructive, Dental Education
Sleep Medicine Education in Dental Schools and Residency Programs in Italian Universities
This study aims to assess whether sleep medicine education is provided within Italian undergraduate dental programs (Degree in Dentistry and Dental Prosthetics) and postgraduate specialization programs in Orthodontics and…
- Conditions
- Sleep Apnea Syndrome, Obstructive, Dental Education, Sleep-disordered Breathing
- Trial name
- Sleep-OD (NCT07624110)
- Testing
- Sleep medicine education questionnaire
- Where
- Italy
- Volunteers
- 70 people
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Obstructive Sleep Apnea
AutoSet for Her Clinical Trial Protocol
The purpose of this study is to assess the efficacy and user preference of the Newport AutoSet for Her in female obstructive sleep apnea (OSA) patients.
- Trial name
- NCT01826513
- Testing
- Standard AutoSet algorithm, Modified AutoSet algorithm
- Where
- Australia
- Volunteers
- 25 people
- Sponsor
- ResMed
Sleep Apnea
Obersvational Study on Effects of CPAP on Depressive Symptoms in OSAS
The official definition of depression or major depressive disorder, is a psychological disorder which is characterised by a persistent low mood or loss of interest in previously pleasurable activities, for over two weeks.
- Trial name
- COAST (NCT05953025)
- Testing
- Questionnaire
- Where
- United Kingdom
- Volunteers
- 101 people
- Sponsor
- Portsmouth Hospitals NHS Trust
Pierre Robin Sequence, Brainstem Dysfunction
Brainstem Dysfunction Involvement in the Pathogenesis of Pierre Robin Sequence
Introduction Pierre Robin Sequence, PRS, incidence is about one hundred births per year in France. The main neonatal clinical manifestations are secondary to airway obstruction and food difficulties related to swallowing…
- Trial name
- DYSROBIN (NCT03423017)
- Testing
- Recording of data
- Where
- 2 sites in France
- Volunteers
- 113 people
- Sponsor
- Hospices Civils de Lyon
Central Sleep Apnea
Central Sleep Apnea Treated by CO2 Supplied by a Novel Device
In general, central sleep apnea is not as common as obstructive sleep apnea but it is common in patients with heart failure. It has been repeatedly shown that central sleep apnea worsens the prognosis of heart failure.
- Trial name
- NCT04907058
- Testing
- novel device with a comfortable mask
- Where
- China
- Volunteers
- 18 people
- Sponsor
- State Key Laboratory of Respiratory Disease
Effects of Training
Effect of Mentoring on Endotracheal Tube Exchange Using a New Device
The purpose of this pilot study is to compare the time it takes to change a breathing tube with a new device, performed by two different groups of anesthesiologists; one group will study on their own how to change the tube, while…
- Trial name
- FACETTE2 (NCT02763189)
- Testing
- Expert mentoring, Self-study
- Where
- United States
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- Wake Forest University Health Sciences
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