Clinical trials: Apnoea
Sleep Disorder; Breathing-Related, Central Apnea
Transcutaneous CO2 Monitoring at Home for Children With Neuromuscular Disease
There is an unmet demand for the evaluation of nocturnal hypoventilation in children with NMD. An ambulatory screening tool that can reliably facilitate timely diagnosis and treatment in these children would be invaluable.
- Conditions
- Sleep Disorder; Breathing-Related, Central Apnea, Neuromuscular Diseases, Obstructive Sleep Apnea
- Trial name
- NCT03478566
- Testing
- Transcutaneous CO2 monitoring
- Where
- Canada
- Volunteers
- 39 people
- Sponsor
- The Hospital for Sick Children
Obstructive Sleep Apnea
Oral Appliance Therapy in Obstructive Sleep Apnea
The aim of the study was to compare the effects of a mandibular advancement device (MAD) with those of nasal continuous positive airway pressure(nCPAP) and of an intra-oral placebo device in obstructive sleep apnea (OSA)…
- Trial name
- NCT00950495
- Testing
- Mandibular Advancement Device (MAD), nasal CPAP
- Where
- Netherlands
- Volunteers
- 64 people
- Sponsor
- VU University of Amsterdam
Sleep Apnea, Stroke
Usefulness of Nasal Continuous Positive Airway Pressure (CPAP) Treatment in Patients With a First Ever Stroke and Sleep Apnea Syndrome
MAIN AIMS: to analyze the efficacy of nasal CPAP treatment in patients with ischemic first-ever stroke and Sleep Apnea Syndrome (SAS) in terms of: early neurological outcome, functional recovery, quality of life influence, stroke…
- Conditions
- Sleep Apnea, Stroke, Cardiovascular Disease
- Trial name
- NCT00202501
- Testing
- Nasal CPAP (Continuous Positive Airway Pressure)
- Where
- Spain
- Volunteers
- 80 people
- Sponsor
- Sociedad Española de Neumología y Cirugía Torácica
Sleep Apnea, Obstructive
Dexmedetomidine and Propofol in Children With History of Obstructive Sleep Apnea
The purpose of this research study is to examine the effects of two commonly used anesthetic drugs, dexmedetomidine and propofol, have on the shape and muscle tone of the upper airway in children, adolescents, and young adults…
- Trial name
- NCT01344759
- Testing
- Dexmedetomidine, Propofol
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Children's Hospital Medical Center, Cincinnati
Obstructive Sleep Apnea, Sleep Apnea, Obstructive
Orthognathic Surgery and Obstructive Sleep Apnea Assessed by Mandibular Jaw Movement Monitoring (SUNRISE-ORTHO)
Orthognathic surgery changes the skeletal framework of the upper airway, but its functional effect on sleep-disordered breathing remains poorly documented, particularly with respect to respiratory effort.
- Conditions
- Obstructive Sleep Apnea, Sleep Apnea, Obstructive, Dentofacial Deformities
- Trial name
- SUNRISE-ORTHO (NCT07910461)
- Testing
- Orthognathic surgery (BSSO with or without Le Fort I osteotomy), Sunrise mandibular jaw movement monitoring, Facial multidetector CT in natural head position
- Where
- Belgium
- Volunteers
- 25 people
- Sponsor
- CHR Sambre et Meuse Site Meuse
Desaturation of Blood, Colonoscopy
The Use of High Flow Nasal Cannula, Standard Face Mask and Standard Nasal Cannula in Morbidly Obese Patients
It is standard practice in the United States and many parts of world to perform Gastrointestinal endoscopy with the patient under deep intravenous sedation.
- Trial name
- NCT03479905
- Testing
- Salter nasal cannula, Face mask, High Flow Nasal Cannula
- Where
- United States
- Volunteers
- 143 people
- Sponsor
- University of Texas Southwestern Medical Center
Apnea Syndrome, Stroke
Relationship Between Sleep Apnea Syndrome and Patent Foramen Ovale Among Victims of Cryptogenic Ischemic Stroke
Obstructive sleep apnea syndrome (OSAS) and patent foramen ovale (FOP) are considered as risk factors for stroke. OSAS generates a pressure increase in the right cavity during inspiratory efforts, which increases the number of…
- Trial name
- NCT04846205
- Testing
- systematic etiological
- Where
- France
- Volunteers
- 159 people
- Sponsor
- Centre Hospitalier Universitaire de Saint Etienne
Heart Failure, OSA - Obstructive Sleep Apnea
Mandibular Advancement to Reduce Ventricular Load and Improve Quality-of-life in Heart Failure
Heart failure with reduced ejection fraction (HFrEF) is a serious condition that limits daily activities and often leads to hospital stays and early death.
- Trial name
- MARVEL-HF (NCT07460505)
- Testing
- Mandibular advancement device
- Where
- Singapore
- Volunteers
- 328 people
- Sponsor
- National University Hospital, Singapore
Obstructive Sleep Apnea of Adult
Real World Experiences of the iNAP® Lite in OSA Adults in Taiwan
A Prospective, Observational, Post-market Surveillance Study to Evaluate the Long-term Safety and Efficacy of the iNAP® Lite Sleep Therapy System in Adults with Obstructive Sleep Apnea
- Trial name
- NCT03559322
- Testing
- iNAP® Lite Sleep Therapy System
- Where
- Taiwan
- Volunteers
- 76 people
- Sponsor
- Somnics, Inc.
Obstructive Sleep Apnea
Optimizing Treatment Effects on OSA-related Clinical and Patient-centered Outcomes Among Blacks
The study is to maximize efficacy of message delivery to achieve desired Obstructive sleep apnea (OSA) adherence goal. Newly diagnosed black patients (n=390, all genders) from participating sleep clinics will be randomly exposed…
- Trial name
- NCT03354520
- Testing
- Tailored Videos, OSA Treatment, Standard Videos
- Where
- United States
- Sponsor
- NYU Langone Health
Snoring, Obstructive Sleep Apnea
Smart Pillows for Enhancing Sleep Quality
The purpose of this study is to examine the impact of smart pillows on the sleep quality of individuals who experience a snoring issue and/or obstructive sleep apnea (OSA), as well as their sleep partners.
- Trial name
- NCT06594627
- Testing
- Smart pillow
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- Indiana University
Sleep Related Breathing Disorder, Upper Airway Resistance Syndrome
Inferior Turbinate Reduction in Pediatric Population Failing Surgery for Sleep Disordered Breathing
This study will examine whether treatment of inferior turbinates in patients with continued symptoms of obstructive sleep apnea, sleep related breathing disorder, snoring, disturbed sleeping, open mouth breathing, and upper…
- Conditions
- Sleep Related Breathing Disorder, Upper Airway Resistance Syndrome, Obstructive Sleep Apnea
- Trial name
- NCT00936494
- Testing
- Cold ablation inferior turbinate reduction
- Where
- United States
- Volunteers
- 2 people, healthy volunteers welcome
- Sponsor
- University of Missouri-Columbia
Sleep Apnea, Obstructive
eXciteOSA for Treatment of Moderate Obstructive Sleep Apnea
The objective of this study is to assess the efficacy of the eXciteOSA device amongst a sample of patients with moderate OSA. The study is a multi-center, prospective, open-label, randomized, parallel-arm trial of eXciteOSA…
- Trial name
- ELMO (NCT05252156)
- Testing
- eXciteOSA
- Where
- 7 sites in United States
- Volunteers
- 62 people
- Sponsor
- Signifier Medical Technologies
Obstructive Sleep Apnea Syndrome
Clinical Impact of 2 Types of Mandibular Retention Devices - Narval O.R.M CadCam Design vs Narval O.R.M Traditional Design - on Obstructive Sleep Apnea (OSA) Therapy: ESTAMPS Study
ESTAMPS is a randomized clinical trial with a crossover design: Main objective is to compare impact of 2 different Mandibular Retention Device (MRD) designs (Narval MRD CadCam (CC) design vs Narval MRD traditional (trad) design)…
- Trial name
- ESTAMPS (NCT02755662)
- Testing
- Mandibular Retention Device
- Where
- France
- Volunteers
- 12 people
- Sponsor
- ResMed
Hypercapnic Respiratory Failure, Pulmonary Disease, Chronic Obstructive
Detecting Systemic Carbon Dioxide Levels With a Novel Biosensor
The study is an open, prospective, single center clinical observational pilot investigation. The aim is to compare the carbon dioxide values measured by the IscAlert sensor, which is inserted in proximity to the nasal mucosa.
- Conditions
- Hypercapnic Respiratory Failure, Pulmonary Disease, Chronic Obstructive, Neuromuscular Diseases, Obesity Hypoventilation Syndrome (OHS)
- Trial name
- DISCO (NCT06367686)
- Testing
- IscAlert sensor
- Where
- Norway
- Volunteers
- 21 people
- Sponsor
- The Hospital of Vestfold
Sleep Apnea Syndrome
Comparing the Sleep Strip OTC™ Accuracy in Screening for Sleep Apnea Syndrome Against the Reference Method, an In-lab Full Night Polysomnographic (PSG)
The primary purpose of this study is to demonstrate the equivalence of the new Sleep Strip OTC(TM) compared to the reference method of an in-lab, attended full-night polysomnographic (PSG) study.
- Trial name
- NCT00942669
- Testing
- SleepStrip OTC(TM)
- Where
- Israel
- Volunteers
- 80 people
- Sponsor
- Scientific Laboratory Products, Ltd.
Obstructive Sleep Apnea
Is the Daytime Sleepiness Based on Epworth Sleepiness Scale a Good Way to Assess Taiwanese With Suspected Obstructive Sleep Apnea.
This observational survey with retrospective follow-up is designed to study the daytime sleepiness based on Epworth Sleepiness Scale a good way or not to assess Taiwanese with suspected obstructive sleep apnea.
- Trial name
- NCT04631783
- Volunteers
- 3,000 people, healthy volunteers welcome
- Sponsor
- Taipei Veterans General Hospital, Taiwan
Apnea of Prematurity
Clinical Study of Caffeine for Apnea of Prematurity
The aim of the present Phase III study is to evaluate the safety, efficacy and pharmacokinetics of Caffeine Citrate for treatment of apnea of prematurity in Japan.
- Trial name
- NCT01408173
- Testing
- NPC-11 for intravenous or oral administration.
- Where
- 3 sites in Japan
- Volunteers
- 24 people
- Sponsor
- Nobelpharma
Apnea, Obstructive, Tonsillitis
Evaluation of the Functional Impact of Adenotonsilectomy
Spirometric assessment of respiratory function before and after adenotonsillectomy surgery
- Conditions
- Apnea, Obstructive, Tonsillitis, Tonsillar Hypertrophy, Respiratory Function Impaired
- Trial name
- NCT05532228
- Testing
- Adenotonsillectomy
- Where
- Portugal
- Volunteers
- 78 people
- Sponsor
- Instituto de Ciências Biomédicas Abel Salazar
Obesity, Obstructive Sleep Apnea
Obstructive Sleep Apnea, Predictors and Bariatric Surgery
Obstructive sleep apnea is defined as a repetitive collapse of the pharynx during sleep (Malhotra, et al. 2012) which cases intermittent hypoxia.
- Conditions
- Obesity, Obstructive Sleep Apnea, Bariatric Surgery Candidate
- Trial name
- NCT03223467
- Testing
- Bariatric surgery
- Volunteers
- 86 people
- Sponsor
- Catholic University of the Sacred Heart
The first 1,020 results can be paged through. Add a filter or change the sort order to reach the rest.