Clinical trials: Apnoea
Sleep Apnea, Obstructive
Virtual Surgery of the Upper Airways
Obstructive sleep apnea (OSA) is a sleep related breathing disorder caused by repetitive collapses of the upper airways resulting in impaired breathing, oxygen desaturation and sleep disturbances.
- Trial name
- VirtuOSA (NCT04829201)
- Testing
- functional septorhinoplasty or oropharyngeal/orthognathic surgery
- Where
- 2 sites in Norway
- Volunteers
- 30 people
- Sponsor
- Norwegian University of Science and Technology
Snoring, Obstructive Sleep Apnea
Vessel Sealing System Uvulopalatoplasty Versus Uvulopalatal Flap
The purpose of this study is to compare vessel sealing system uvulopalatoplasty (VSSU) to the traditional uvulopalatal flap (UPF) in the treatment of sleep-disordered breathing with special regard to intraoperative bleeding…
- Trial name
- NCT00806637
- Testing
- Vessel sealing system uvulopalatoplasty (VSSU), Uvulopalatal flap (UPF)
- Where
- Thailand
- Volunteers
- 30 people
- Sponsor
- Chulalongkorn University
Chronic Obstructive Airway Disease
Cardiac Hemodynamics in Overlap Syndrome (COPD With Obstructive Sleep Apnea)
Patients with both sleep apnea and COPD have overlap syndrome, but their optimal management is not known. We plan to conduct a randomized trial of of bi-level PAP vs.
- Trial name
- NCT01261377
- Testing
- Bi-level positive airway pressure (BPAP), Oxygen, CPAP
- Where
- 2 sites in United States
- Sponsor
- Brigham and Women's Hospital
Apnea of Prematurity
Stochastic Resonance Mattress (Physiological Interventions) and Biomarkers for Enhancing Neonatal Health
The purpose of this study is to explore physiological interventions and biomarkers for Apnea of Prematurity in newborn infants.
- Trial name
- NCT01643057
- Testing
- Stochastic Resonance Mattress
- Where
- United States
- Volunteers
- 36 people
- Sponsor
- Wyss Institute at Harvard University
Hypertension
Antihypertensive Effect of Continuous Positive Airway Pressure in Resistant Hypertensive Patients With Sleep Apnea
Obstructive sleep apnea syndrome (OSAS) has been linked to resistant hypertension, but the effect of treatment of OSAS on the resistant hypertension have no been established.
- Trial name
- NCT00929175
- Testing
- active CPAP
- Where
- Brazil
- Volunteers
- 45 people
- Sponsor
- Hospital de Clinicas de Porto Alegre
Sleep Apnea, Obstructive
Pediatric Obstructive Sleep Apnea Diagnosis by Respiratory Polygraphy
Respiratory polygraphy (RP) can be used to detect obstructive sleep apnea syndrome in children (OSA) , but it underestimates the obstructive apnea-hypopnea index (OAHI) because hypopneas associated with cortical arousals are not…
- Trial name
- NCT06754800
- Testing
- Polysomnography in routine care
- Where
- France
- Volunteers
- 95 people
- Sponsor
- Central Hospital, Nancy, France
Pain, Hypoxia
Effects of Walking Apnea at Low Lung Volume on Hypoalgesia, Cardiovascular Function and Respiratory Function
The aim of this randomized controlled study is to explore the hypoalgesic response of a 6 minutes of intermittent walking apneas training session at low lung volume in healthy subjects; also, as secondary objectives, to analyze…
- Conditions
- Pain, Hypoxia, Hypercapnia, Apnea
- Trial name
- NCT06158295
- Testing
- Voluntary apnoea
- Where
- Spain
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Centro Universitario La Salle
Sleep Apnea
Comparison Of The Berlin Questionnaire To The Portland Sleep Quiz
This trial is enrolling patients who are already being seen at OHSU sleep disorder center or have been referred for clinical reasons by their physician to the OHSU sleep disorder center and are going to have a sleep study that…
- Trial name
- NCT01269073
- Where
- United States
- Sponsor
- Akram Khan
Sleep Apnea, Obstructive, Quality of Life
QoL in OSA patiënts Treated With MMA Surgery.
The aim of this observational study is to evaluate the impact of maxillomandibular advancement surgery on the quality of life in patients treated with obstructive sleep apnea.
- Trial name
- QOMAS (NCT06386341)
- Testing
- Maxillomandibular Advancement Surgery
- Where
- Netherlands
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Diakonessenhuis, Utrecht
Atrial Fibrillation, Osa Syndrome
PRevalence of Obstructive Sleep apnoEa and Reduction of Promoters in AF
This study aims to identify how many patients who have atrial fibrillation, also have sleep apnoea. This is important because sleep apnoea can be a trigger to atrial fibrillation and it can be corrected with a simple…
- Trial name
- PROSERPin-AF (NCT05784077)
- Testing
- Polysomnography, Lifestyle counselling
- Where
- Italy
- Volunteers
- 343 people
- Sponsor
- Istituto Auxologico Italiano
Apnea, Obstructive
Validation of the French Version of the OSA-18 Questionnaire
Obstructive sleep apnea (OSA) is characterized by repetitive partial and/or total closure of the upper airway during sleep, inducing oxygen desaturation and sleep disturbance. Its prevalence in the pediatric population is 1-5%.
- Trial name
- French OSA18 (NCT07136909)
- Testing
- Completion of the OSA-18 questionnaire by parents, during hospitalization planned as part of routine care.
- Where
- France
- Volunteers
- 200 people
- Sponsor
- Hospices Civils de Lyon
Obstructive Sleep Apnea, Sleep Apnea
Recording of Multiple Nights Using a New Contactless Device (Sleepiz One Connect) in Obstructive Sleep Apnea
The need for multiple night testing is well recognized in sleep medicine because of a considerable and relevant night-to-night variability.
- Conditions
- Obstructive Sleep Apnea, Sleep Apnea, Respiratory Tract Disease, Respiration Disorder
- Trial name
- NCT05134402
- Testing
- Sleepiz One Connect
- Where
- Switzerland
- Volunteers
- 25 people
- Sponsor
- Samuel Tschopp
Enuresis, Obstructive Sleep Apnea
Intranasal Steroids for the Treatment of Nocturnal Enuresis With Associated Obstructive Sleep Apnea
Enuresis (E) or bedwetting is a common pediatric complaint, and recent research has discovered a link with obstructive sleep apnea (OSA).
- Conditions
- Enuresis, Obstructive Sleep Apnea, Sleep Disordered Breathing
- Trial name
- NCT01861145
- Testing
- Bed Alarm, Nasonex
- Where
- 2 sites in Canada
- Sponsor
- University of Alberta
Obesity &Amp; Overweight, Hypertension
A Prospective Randomnised Controlled Trial Comparing Overall Patient Compliance in a Bariatric Surgical Pathway Using the Standard Versus a More Intensified and Interactive Version of the "Get Ready" Smartphone Application.
The aim of this study is to assess the impact of a newly intensified digital platform following bariatric surgery. This will be measured using several questionnaires.
- Conditions
- Obesity &Amp; Overweight, Hypertension, Obstructive Sleep Apnea (OSAS), Diabetes Mellitus ( Type 1 and Type 2)
- Trial name
- NCT07297342
- Testing
- GetReady application, Intensified GetReady application
- Where
- Belgium
- Volunteers
- 200 people
- Sponsor
- Sint Dimpna Ziekenhuis Geel
Apnea, Snoring
Polidocanol Sclerotherapy of Pharynges for Obstructive Sleep Apnea (OSA) and Snoring Subjects(SS)
The aim of this prospective study is to evaluate the results of polidocanol sclerotherapy of pharynx for OSAS \& SS,to reduce pharyngeal compliance.
- Trial name
- NCT00399451
- Testing
- Polidocanol Sclerotherapy
- Volunteers
- 30 people
- Sponsor
- Liaoyang Central Hospital
Sleep Apnea, Obstructive
The Induction of IL-6 by NF-kB in PBMC in OSA
Aim of study: 1. To compare the level of IL-6 mRNA expression in peripheral blood monocytes between normal subjects and patients with OSAS 2.
- Trial name
- OSA (NCT00498381)
- Testing
- CPAP
- Volunteers
- 20 people
- Sponsor
- National Taiwan University Hospital
Sleep Apnea, Obstructive
The Effect of Orofacial Myofunctional Therapy With Autofeedback on Obstructive Sleep Apnea
The overall aim of this study is to estimate the effect of orofacial myofunctional therapy (OMT) plus auto-monitoring compared to auto-monitoring alone.
- Trial name
- OMTAOSA (NCT06079073)
- Testing
- Orofacial myofunctional therapy with autofeedback
- Where
- 2 sites in Estonia, Norway
- Volunteers
- 106 people
- Sponsor
- University Hospital, Akershus
Periodontitis, Obstructive Sleep Apnea
Effect of Non-surgical Periodontal Treatment on Oxidative Stress and Antioxidant Status in OSAS
The main objective of this study is to compare the effect of the non-surgical periodontal treatment on serum and saliva oxidative stress parameters in patients with periodontitis and obstructive sleep apnea syndrome (OSAS) and in…
- Conditions
- Periodontitis, Obstructive Sleep Apnea, OSAS
- Trial name
- OSAS (NCT03268473)
- Testing
- Experimental, Control
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people
- Sponsor
- Bezmialem Vakif University
Central Sleep Apnea
Belgian Central Sleep Apnea REgistry
This study evaluates different factors that determine the treatment choice and treatment compliance in patients with central sleep apnea. All patients will receive routine care (registry).
- Trial name
- B-CARE (NCT03621566)
- Testing
- No intervention
- Where
- 14 sites in Belgium
- Volunteers
- 1,500 people
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Obstructive Sleep Apnea
A Comparison of CPAP With and Without Humidification: A Pilot Study
To compare a group of patients with our standard treatment of continuous positive airway pressure (CPAP) and another group of patients with CPAP and a humidifier attached.
- Trial name
- NCT02423681
- Testing
- ThermoSmart, Without ThermoSmart
- Where
- United Kingdom
- Volunteers
- 20 people
- Sponsor
- Fisher and Paykel Healthcare
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