Clinical trials: Apnoea
Obstructive Sleep Apnea, Erectile Dysfunction
Changing Lifestyle in OSA Males Who Suffer Metabolic Syndrome and Impotence: Is There a Response?
The problems like metabolic syndrome and sexual impotence in males with obstructive sleep apnea are common. continuous passive airway pressure (CPAP) is an authorized treatment for this type of apnea but still the recommendations…
- Conditions
- Obstructive Sleep Apnea, Erectile Dysfunction, Metabolic Syndrome
- Trial name
- NCT06960746
- Testing
- lifestyle changing plus CPAP, CPAP
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Cairo University
Sleep Apnea, Obstructive
Safety and Efficacy Study of Dronabinol to Treat Obstructive Sleep Apnea
This is a proof of concept study to determine the safety and efficacy of dronabinol for the treatment of obstructive sleep apnea syndrome (OSA).
- Trial name
- PACE (NCT01755091)
- Testing
- Dronabinol
- Where
- 2 sites in United States
- Volunteers
- 75 people
- Sponsor
- University of Illinois Chicago
Obstructive Sleep Apnea (OSA), Snoring
Effects of Frequency Adjustment in Functional Electrical Stimulation on Genioglossus Muscle Activity
This single-group interventional study investigates the safety and physiologic effects of functional electrical stimulation (FES) applied to the tongue and submental muscles in adults at high risk for sleep apnea.
- Trial name
- NCT07466888
- Testing
- Functional Electrical Stimulation Device
- Where
- South Korea
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Seoul National University Bundang Hospital
Obstructive Sleep Apnea (OSA), Excessive Daytime Sleepiness
SLEEPINESS - a Search for a Biomarker of Excessive Daytime Sleepiness in Severe Obstructive Sleep Apnoea - An Explorative Study
Study aim: This study aims to use a new brainwave monitoring device that meassure brainwaves 24 hours a day to create better understanding of sleep-wake interplay as a biomarker for excessive daytime sleepiness because of…
- Trial name
- NCT06711159
- Testing
- continuous positive airway pressure
- Where
- Denmark
- Volunteers
- 15 people
- Sponsor
- Zealand University Hospital
Obstructive Sleep Apnea
Comparative Assessment of Sleep Positive Airway Pressure Modalities (CASPAM)
Obstructive sleep apnea (OSA) has been one of the topmost global health problems. It is an underdiagnosed disease which have a huge burden on healthcare if left untreated.
- Trial name
- CASPAM (NCT06564896)
- Testing
- CPAP Airsense 10 vs Air-Mini
- Where
- Malaysia
- Volunteers
- 50 people
- Sponsor
- National University of Malaysia
Obstructive Sleep Apnea
CPAP Effect on Vascular Function in Obstructive Sleep Apnea
Obstructive sleep apnea syndrome is responsible of endothelial dysfunction, which is a independent cardio-vascular risk factor. Assessment of pulse wave velocity (PWV) and peripheral arterial tone (PAT) are study measurements of…
- Trial name
- VNI-SOH2 (NCT02623088)
- Testing
- PAP Therapies (CPAP)
- Where
- France
- Volunteers
- 107 people
- Sponsor
- University Hospital, Grenoble
Sleep Apnea, Obstructive
Minimally Invasive Hypoglossal Nerve Stimulation Study (Lingual Study)
The purpose of this study is to assess the effect of Transvenous Hypoglossal Nerve Stimulation (tHGNS) on tongue position in the upper airway.
- Trial name
- Lingual (NCT03210142)
- Testing
- Transvenous hypoglossal nerve stimulation
- Where
- 3 sites in Hong Kong
- Volunteers
- 23 people
- Sponsor
- Medtronic Cardiac Rhythm and Heart Failure
Laryngeal Disease
Randomized Controlled Trial:High-flow Oxygen Therapy and Tracheal Intubation for Laryngeal Microsurgery
Over time, the accumulation of carbon dioxide reduces the pressure gradient for the alveolar transfer of oxygen, limiting the successful duration of apneic oxygenation.
- Trial name
- NIRS_ORL (NCT05400642)
- Testing
- THRIVE, mechanical ventilation
- Where
- Italy
- Volunteers
- 30 people
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Obstructive Sleep Apnea of Adult
Comparative Study of the ANNE™ One System to Diagnose Obstructive Sleep Apnea
The main objective of this study is to evaluate the accuracy of the ANNE Sleep system for the diagnosis of obstructive sleep apnea (OSA) in adults
- Trial name
- NCT04643782
- Testing
- ANNE Sleep
- Where
- 4 sites in United States
- Volunteers
- 287 people, healthy volunteers welcome
- Sponsor
- Northwestern University
Obstructive Sleep Apnea (OSAS)
Night Balance for Positional Obstructive Sleep Apnea Syndrome (POSAS)
POSAS can be treated with CPAP however there is now evidence from a few studies that Night Balance is effective in POSAS. Night Balance seems to be better accepted than CPAP so we would like to examine if we could find similar…
- Trial name
- POSAS (NCT02114424)
- Testing
- Positional vibrator belt
- Where
- Denmark
- Volunteers
- 100 people
- Sponsor
- Glostrup University Hospital, Copenhagen
Obstructive Sleep Apnea
Prospective Cohort Study of Patients Intolerant to High Pressure Under Continuous Positive Airway Pressure Treated With Bilevel Positive Airway Pressure as Second-line Therapy.
Prospective observational study of obstructive Sleep Apnea patients treated with Bilevel Positive Airway Pressure: AirCurve 10 VAutoTM
- Trial name
- PoP IN VAuto (NCT02930460)
- Where
- 8 sites in France
- Volunteers
- 30 people
- Sponsor
- ResMed
Obstructive Sleep Apnea
Acetazolamide for Obstructive Sleep Apnea to Improve Heart Health
Obstructive sleep apnea (OSA) is a severe type of snoring causing people to choke in their sleep. It affects millions of Americans, causing many health problems.
- Trial name
- ACE-Of-HEARTs (NCT05616260)
- Testing
- Acetazolamide, Continuous Positive Airway Pressure
- Where
- United States
- Volunteers
- 54 people
- Sponsor
- University of California, San Diego
Obstructive Sleep Apnea, Spinal Cord Injuries
Obstructive Sleep Apnea Management in People With Spinal Cord Injury
The prevalence of obstructive sleep apnea (OSA) is a significantly higher in people after spinal cord injury (SCI) than in the general population.
- Trial name
- NCT04962165
- Testing
- Mandibular Advancement Device
- Where
- Czechia
- Volunteers
- 60 people
- Sponsor
- University Hospital, Motol
Tonsillectomy Postoperative Adverse Events
Factors Predictive of Adverse Postoperative Outcomes in Children Undergoing Tonsillectomy
The purposes of the study are to identify 1) the patient (demographic and clinical) and health care system factors predictive of immediate and late postoperative adverse outcomes in children undergoing tonsillectomy.
- Trial name
- NCT01669993
- Where
- United States
- Volunteers
- 2,400 people
- Sponsor
- Children's Hospital Medical Center, Cincinnati
Obstructive Sleep Apnea, Type 2 Diabetes
Effects of Continuous Positive Airway Pressure (CPAP) Treatment on Glucose Control in Patients With Type 2 Diabetes
The overall goal of the proposed protocol is to rigorously test the hypothesis that CPAP treatment has beneficial effects on glycemic control in patients with both type 2 diabetes (T2DM) and obstructive sleep apnea (OSA).
- Trial name
- CPAP (NCT01136785)
- Testing
- active CPAP Therapy
- Where
- United States
- Volunteers
- 22 people
- Sponsor
- University of Chicago
Obstructive Sleep Apnea
The Severity Of Individual Breathing Cessation Events In Diagnostics Of Obstructive Sleep Apnea
Obstructive sleep apnea (OSA) is a common nocturnal breathing disorder characterized by complete (apnea) and partial (hypopnea) breathing cessations during sleep.
- Trial name
- NCT03232658
- Where
- 4 sites in Australia, Finland and 1 more
- Volunteers
- 10,000 people
- Sponsor
- Loewenstein Hospital
OSA - Obstructive Sleep Apnea, Coronary Microvascular Dysfunction (CMD)
The Correlation Between Obstructive Sleep Apnea-Related Nocturnal Hypoxemia Parameters and Coronary Microvascular Dysfunction: A Prospective Cohort Study (SLEEP-CMD)
In a cohort of patients with suspected myocardial ischemia undergoing sleep studies, the objectives of this study were: 1. To determine the association between various obstructive sleep apnea (OSA)-related nocturnal hypoxemia…
- Conditions
- OSA - Obstructive Sleep Apnea, Coronary Microvascular Dysfunction (CMD), Coronary Artery Disease (CAD)
- Trial name
- SLEEP-CMD (NCT07315399)
- Testing
- Polysomnography
- Where
- China
- Volunteers
- 560 people
- Sponsor
- Beijing Anzhen Hospital
Sleep Apnea
Sleep Apnea. Concordance Between Non-reference and Reference Centres
When a disorder is as prevalent as sleep apnea hypopnea syndrome various medical levels and strategies should be implicated. We to evaluate the degree of concordance in management between a sleep reference centre and…
- Trial name
- NCT00424658
- Testing
- SAHS diagnosis
- Where
- 2 sites in Spain
- Volunteers
- 90 people
- Sponsor
- Hospital Clinic of Barcelona
Obstructive Sleep Apnea Syndrome
Osteopathy and Obstructive Sleep Apnea Syndrome
The main objective is to evaluate an osteopathic compression of pterygopalatine node on sleep obstructive apnea syndrome (OSA).
- Trial name
- NCT01193738
- Testing
- osteopathic compression of Pterygopalatine node
- Where
- France
- Volunteers
- 10 people
- Sponsor
- Valerie Attali
Obesity Hypoventilation Syndrome
A Trial of Rehabilitation in Obesity Hypoventilation Syndrome (OHS)
Obesity is an escalating problem in the UK and a proportion of these patients have a condition known as Obesity Hypoventilation Syndrome (OHS).
- Trial name
- NCT01483716
- Testing
- Rehabilitation
- Where
- United Kingdom
- Volunteers
- 37 people
- Sponsor
- Guy's and St Thomas' NHS Foundation Trust
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