Clinical trials: Apnoea
Obesity Hypoventilation Syndrome
Non Invasive Ventilation : Efficacy of a New Ventilatory Mode in Patients With OHS
In 2012, it has announced the availability of the new ventilator (BiPAP- A40), which could offer potential advantages over fixed level pressure support, in particular, in patients with obesity hypoventilation syndrome (OHS).
- Trial name
- NCT01757444
- Testing
- BiPAP - A40, BiPAP - ST
- Where
- 11 sites in France
- Volunteers
- 60 people
- Sponsor
- Association Nationale pour les Traitements A Domicile, les Innovations et la Recherche
Obstructive Sleep Apnea Syndrome
Retinal Vascular Network and Obstructive Sleep Apnea
Obstructive sleep apnea syndrome (OSA) is thought to lead to systemic vascular lesions that may be preceded by early microvascular lesions in the eyes and in particular in the retina.
- Trial name
- ORNET (NCT03979001)
- Testing
- complete ophthalmological examination
- Where
- France
- Volunteers
- 166 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire Dijon
Sleep Disordered Breathing, Obstructive Sleep Apnea
The Evaluation of a Mask Seal/Mask for the Treatment of Obstructive Sleep Apnea (OSA)
This investigation is designed to evaluate the performance as well as the patients overall acceptance of the seal/mask.
- Trial name
- NCT03092921
- Testing
- F&P Mask Seal, F&P Mask
- Where
- New Zealand
- Volunteers
- 18 people
- Sponsor
- Fisher and Paykel Healthcare
Obstructive Sleep Apnea
Ansa Cervicalis and Hypoglossal Nerve Stimulation in OSA
Polysomnography (PSG) and drug-induced sleep endoscopy (DISE) are widely used diagnostic studies for assessing obstructive sleep apnea (OSA) severity and collapse patterns of the upper airway anatomy during sleep.
- Trial name
- NCT05501236
- Testing
- Grass S88 Muscle Stimulator
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Vanderbilt University Medical Center
Obstructive Sleep Apnea (OSA)
Myofunctional Therapy for Children With OSA
Myofunctional therapy (MFT) has been proposed as an adjunctive therapy for obstructive sleep apnoea (OSA) in children. Some studies have reported improved sleep parameters and reduced oral breathing after MFT.
- Trial name
- NCT07249944
- Testing
- Myofunctional therapy
- Where
- Hong Kong
- Volunteers
- 174 people
- Sponsor
- Chinese University of Hong Kong
Obstructive Sleep Apnea
Acetazolamide Add-On Therapy to OSA Surgery
Surgical procedures are routinely performed as an alternative to continuous positive airway pressure treatment in patients with obstructive sleep apnea (OSA). However, the response to surgery is often variable.
- Trial name
- ACTOS (NCT04227093)
- Testing
- Acetazolamide
- Where
- Belgium
- Volunteers
- 26 people
- Sponsor
- University Hospital, Antwerp
Obstructive Sleep Apnea, Diagnostic Imaging
The Role of Sub-mental Ultrasonography in Diagnosing Obstructive Sleep Apnea and Its Correlation With Subjective Scales
The investigators hypothesize that sub-mental ultrasonography measures are strongly correlated with the severity of Obstructive Sleep Apnea Syndrome and the related specific subjective scales.
- Conditions
- Obstructive Sleep Apnea, Diagnostic Imaging, Ultrasound
- Trial name
- NCT03832244
- Testing
- Sub-mental ultrasonography
- Where
- Turkey (Türkiye)
- Volunteers
- 199 people, healthy volunteers welcome
- Sponsor
- Bartin State Hospital
Endotracheal Tube Exchange, Airway Management
Bronchoscopic Versus Airway Exchange Catheter-Guided Endotracheal Tube Exchange
This prospective experimental study compares two methods for replacing an endotracheal tube in Thiel-embalmed body donors. The conventional method uses an airway exchange catheter based on the Seldinger technique, whereas the…
- Conditions
- Endotracheal Tube Exchange, Airway Management, Endotracheal Intubation, Reintubation
- Trial name
- Bronchex (NCT07706309)
- Testing
- Airway Exchange Catheter-Guided Endotracheal Tube Exchange, Bronchoscope-Guided Endotracheal Tube Exchange
- Where
- Switzerland
- Volunteers
- 2 people
- Sponsor
- Léo Franchetti
Obstructive Sleep Apnea
Magnetic Apnea Prevention(MAGNAP) Device to Treat Obstructive Sleep Apnea:First-In-Human Study of Feasibility and Safety
The purpose of this study is to determine the safety and feasibility of the Magnap magnetic device in the treatment of obstructive sleep apnea (OSA).
- Trial name
- MAGNAP (NCT02431507)
- Testing
- Magnap
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Michael Harrison
Sleep Disorders, Sleep Apnea
Bedside Sleep Medicine
The investigators aimed to evaluated the role of bedside sleep medicine in an cardiology intensive care unit. The patients will be submitted to a overnight polysomnography.
- Conditions
- Sleep Disorders, Sleep Apnea, Acute Myocardial Infarction, Acute Decompensated Heart Failure
- Trial name
- NCT01924507
- Testing
- CPAP
- Where
- Brazil
- Volunteers
- 400 people
- Sponsor
- Associação Fundo de Incentivo à Pesquisa
Sleep-disordered Breathing, Obstructive Sleep Apnea
Comparison of Sleep Study Results After Partial Intracapsular Tonsillectomy Versus Total Tonsillectomy
The purpose of this study is to demonstrate similar improvements in sleep-disordered breathing as determined by sleep study with microdebrider-assisted partial intracapsular tonsillectomy and adenoidectomy versus total Bovie…
- Trial name
- NCT00887471
- Testing
- PITA or T&A
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- State University of New York - Downstate Medical Center
Sleep Apnea Syndromes
Amara View Benchmark Study
This randomized crossover, benchmark clinical trial aims to compare the Philips Amara View and ResMed AirFit F40 minimal contact full face masks on patient preference of mask attributes and usage parameters.
- Trial name
- NCT06535932
- Testing
- Amara View Minimal Contact Full Face Mask, F40 Minimal Contact Full Face Mask
- Where
- United States
- Volunteers
- 35 people
- Sponsor
- Philips Clinical & Medical Affairs Global
Healthy
Autonomic Nervous System Activity, Aging and Sleep Apnea/Hypopnea
The regulatory effects of the autonomic nervous system (ANS) concern almost all organs which permanently feed information back to this global biological vigilance system controlling allostasis.
- Trial name
- SYNAPSE (NCT00766584)
- Testing
- Sleep apnea/hypopnea detection
- Where
- France
- Volunteers
- 852 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire de Saint Etienne
Pediatric Surgery, Rapid Sequence Induction
High-flow Nasal Cannula Oxygenation During Rapid Sequence Induction in Children
This randomised study aims to compare the utilization of high-flow humidified nasal oxygenation (HFNO) with standard care, using apnoeic facemask oxygenation, during rapid sequence induction (RSI) of anesthesia in young children.
- Trial name
- OPTINECK (NCT05063084)
- Testing
- Optiflow - HFNO, Classic
- Where
- France
- Volunteers
- 44 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Sleep Apnea
New Approach in the Study of the Autonomic Nervous System Through Cardiac Variability in Sleep Apnea Syndrome.
The main objective of this study is to compare the different variations of the cardiac variability index measured thanks to the technique developed by the CIC-IT between subjects with severe SAS and healthy subjects with sleep…
- Trial name
- HRVSAS (NCT06808464)
- Where
- France
- Volunteers
- 97 people, healthy volunteers welcome
- Sponsor
- University Hospital, Lille
Morbid Obesity
Apneic Oxygenation for Morbid Obese Parturient in cs
The aim of this study is to compare the effect of apneic preoxygenation to conventional preoxygenation on the oxygen desaturation in morbid obese parturient performing elective caesarean section under general anesthesia.
- Trial name
- NCT05021549
- Testing
- nasal prong
- Where
- 2 sites in Egypt
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Obstructive Sleep Apnea
Long-term CPAP Effect with Obstructive Sleep Apnea: a Telemedicine-based
we hypothesize that long-term CPAP could results in increase weight and muscle composite by changing intake content and hormone and the effect was influenced by presence of CVD, social jet lag, and CPAP compliance.
- Trial name
- MSLS-LT (NCT06738940)
- Testing
- CPAP
- Where
- Taiwan
- Volunteers
- 100 people
- Sponsor
- National Taiwan University Hospital
Obstructive Sleep Apnea (OSA)
A Comparative Effectiveness Study of Positive Airway Pressure (PAP) Therapy, Dental Device, and Atomoxetine-Oxybutynin for Treatment of Obstructive Sleep Apnea in Adults
Researchers want to identify which treatments for obstructive sleep apnea (OSA) work best and are easiest for patients to use consistently.
- Trial name
- ADAPT-OSA (NCT07679282)
- Testing
- Positive airway pressure (PAP) therapy, Sleep dental device, Atomoxetine-oxybutynin
- Where
- 4 sites in United States
- Volunteers
- 2,400 people
- Sponsor
- Sairam Parthasarathy
Sleep Apnea Syndrome, Metabolic Syndrome
Continuous Positive Airway Pressure in Sleep Apnea Syndrome: Effects on Metabolic Syndrome and Cardiac Damage
To assess in moderate to severe Obstructive Sleep Apnea the effects of one year therapy with nighttime continuous positive airway pressure ventilation on the prevalence of metabolic syndrome and cardiovascular damage.
- Conditions
- Sleep Apnea Syndrome, Metabolic Syndrome, Cardiac Remodelling, Continuous Positive Airway Pressure Ventilation
- Trial name
- NCT00517777
- Testing
- continuous positive airway pressure ventilation, dietary and life style recommendations
- Where
- Italy
- Volunteers
- 100 people
- Sponsor
- Università degli Studi dell'Insubria
Obstructive Sleep Apnea
Ambulatory Blood Pressure Control and Cognition in Patients With Obstructive Sleep Apnea (AMPLE)
To compare the blood pressure control and cognitive responses of three groups of patients: those diagnosed with Obstructive Sleep Apnea (OSA) and treated with Continuous Positive Airway Pressure (CPAP) for at least six months…
- Trial name
- AMPLE (NCT06463002)
- Testing
- Ambulatory blood pressure monitoring and Montreal Cognitive Assessment
- Where
- Singapore
- Volunteers
- 150 people
- Sponsor
- National University Hospital, Singapore
The first 1,020 results can be paged through. Add a filter or change the sort order to reach the rest.