Clinical trials: Apnoea
Tonsillitis, Obstructive Sleep Apnea of Child
Steroids and Pain Control After Tonsillectomy
This research study aims to find out if a single oral dose of steroid after tonsillectomy will reduce pain and decrease the need for narcotic medications.
- Trial name
- NCT03995628
- Testing
- Dexamethasone
- Where
- United States
- Volunteers
- 163 people
- Sponsor
- Medical University of South Carolina
Sleep Apnea
Effect of High Flow Nasal Cannula Versus Continues Positive Airway Pressure in Adults With Obstructive Sleep Apnea
The participants whom undergo Polysomnography study (Sleep study) and are found to have mild, moderate or severe Obstructive Sleep Apnea (OSA) will have two consecutive titration nights.
- Trial name
- NCT05475119
- Testing
- Continuous Positive Airway Pressure (CPAP), High Flow Nasal Cannula (HFNC)
- Where
- Saudi Arabia
- Volunteers
- 40 people
- Sponsor
- King Abdulaziz University
Obstructive Sleep Apnea
Dual Obstructive Sleep Apnea Therapy
Continuous positive airway pressure (CPAP) is considered the gold standard therapy for obstructive sleep apnea (OSA). However, CPAP users sometimes experience pressure-related discomfort.
- Trial name
- DOT (NCT03435731)
- Testing
- Dual Therapy
- Where
- 2 sites in Canada
- Volunteers
- 30 people
- Sponsor
- University of British Columbia
OSA, SCI/D
Novel by Upper Airway Respiratory Muscle Training to Treat OSA in Chronic SCI
It is estimated that spinal cord injury (SCI) affects approximately 12,000 new individuals every year in the United States, with the majority are cervical and/or upper thoracic injuries.
- Conditions
- OSA, SCI/D, Upper Airway Exercise
- Trial name
- NOURMT-OSA (NCT03664765)
- Testing
- UA and RMT
- Where
- United States
- Volunteers
- 29 people
- Sponsor
- VA Office of Research and Development
Sleep Apnea Obstructive (OSA)
Micromanaging Human Sleep Physiology to Treat Sleep Apnea and Other Disorders
This study will examine whether a combination of breathing training during wake and targeted reactivation of the training during sleep can induce breathing changes during sleep and subsequent cognitive benefits during wake.
- Trial name
- NCT06926036
- Testing
- Wake training + TMR
- Where
- United States
- Volunteers
- 18 people
- Sponsor
- Northwestern University
Obstructive Sleep Apnea
Immunological Consequences of Obstructive Sleep Apnea
Obstructive sleep apnea (OSA) is a medical problem whose importance is increasing in recognition and awareness. OSA is associated with the development of hypertension and other cardiovascular diseases (1,2).
- Trial name
- NCT00214071
- Testing
- Influenza vaccine
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Wisconsin, Madison
Idiopathic Pulmonary Fibrosis, Obstructive Sleep Apnea
Effect of CPAP on Abnormal Gastroesophageal Reflux and Lung Inflammation in IPF
This study will evaluate the effect of CPAP therapy on esophageal pH and lung inflammation in patients with idiopathic pulmonary fibrosis (IPF) and sleep apnea.
- Conditions
- Idiopathic Pulmonary Fibrosis, Obstructive Sleep Apnea, Gastro Esophageal Reflux
- Trial name
- NCT05359965
- Testing
- Positive Airway Pressure
- Where
- United States
- Volunteers
- 7 people
- Sponsor
- University of Arizona
Down Syndrome, Obstructive Sleep Apnea
Computer Models of Airways in Children and Young Adults With Sleep Apnea and Down Syndrome
The purpose of this research study is to develop a way of predicting with computers how surgery on the airway will affect night time breathing called Obstructive Sleep Apnea (OSA) in children with Down Syndrome.
- Trial name
- DYMOSA (NCT01902407)
- Where
- United States
- Volunteers
- 81 people
- Sponsor
- Children's Hospital Medical Center, Cincinnati
Sleep Apnea
Health Coaching for Positive Airway Pressure Adherence
This study tested a low-resource, brief telephonic health coaching intervention to improve adherence to positive airway pressure therapy for treatment of sleep apnea.
- Trial name
- NCT04067128
- Testing
- Health coaching
- Where
- United States
- Volunteers
- 131 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Obstructive Sleep Apnea
LTR for Treatment of Obstructive Sleep Apnea
Study of tongue implant for treatment of obstructive sleep apnea
- Trial name
- NCT03066765
- Testing
- Linguaflex Tongue Retractor
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Linguaflex, Inc.
Dyslipidemia
Thyroxin Treatment in Sub Clinical Hypothyroidism, on the Apnea Hypopnea Index Score, Lipids and Highly Sensitive CRP
Obstructive sleep apnea (OSA) and hypothyroidism are both commonly found in clinical practice, and share a number of symptoms and clinical features.
- Trial name
- NCT01486667
- Testing
- levothyroxine, sugar pill
- Where
- Saudi Arabia
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- King Saud University
Apnea of Prematurity, Desaturation of Blood
Arterial Oxygen Saturation on Ventilatory Stability in Extremely Premature Infants
This is a prospective crossover study to compare the within-subject effect of the two target ranges of arterial oxygen saturation (SpO2), both within the clinically recommended range of 90- 95%.
- Conditions
- Apnea of Prematurity, Desaturation of Blood, Central Apnea, Periodic Breathing
- Trial name
- NCT03695900
- Testing
- Targeting SpO2 at 93-95%, Targeting SpO2 at 90-92%
- Where
- United States
- Volunteers
- 19 people
- Sponsor
- University of Miami
Obstructive Sleep Disordered Breathing
Outcomes of Partial Versus Complete Tonsillectomy for Obstructive Sleep Disordered Breathing
Introduction: There is currently no long-term study, which compares the outcomes of partial tonsillectomy to conventional tonsillectomy.
- Trial name
- NCT00519402
- Testing
- tonsillar examination and questionnaire completion
- Where
- United States
- Sponsor
- The Cleveland Clinic
Obstructive Sleep Apnea, Pathophysiology
Mechanisms of Pharyngeal Collapse in Sleep Apnea, Study A
In obstructive sleep apnea, the upper airway recurrently closes during sleep. The mechanisms that lead to airway closure are not completely understood.
- Trial name
- NCT01728974
- Testing
- Pharyngeal topical anesthesia
- Where
- United States
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Brigham and Women's Hospital
Obstructive Sleep Apnea
Obstructive Sleep Apnea (OSA) Anesthesia and Positive Airway Pressure
To determine if autotitrating positive airway pressure (APAP) naïve patients with OSA can successfully use APAP following general anesthesia.
- Trial name
- OSA (NCT01219660)
- Volunteers
- 78 people, healthy volunteers welcome
- Sponsor
- University of California, San Diego
Sleep Apnea Syndromes
Novel Device for Screening Patients With Symptoms of OSA
An innovative ring type oxymetry will be wore by patient undergoing sleep study to validate it's accuracy and usefulness as a screening device for patients with symptoms of OSA
- Trial name
- NCT03157440
- Testing
- Ring oxymetry
- Where
- Hong Kong
- Volunteers
- 97 people
- Sponsor
- Chinese University of Hong Kong
Obstructive Sleep Apnea
KPAP vs EPR for Comfort
The KPAP EPR Home is a randomized, crossover study in which subjective comfort will be compared between SleepRes APAP + KPAP and ResMed APAP + EPR.
- Trial name
- NCT07530510
- Testing
- APAP + KPAP, APAP + EPR
- Volunteers
- 24 people
- Sponsor
- SleepRes Inc.
Obstructive Sleep Apnea Syndrome
Predictive Factors for Occlusal Changes in Obstructive Sleep Apnea Treatment With Mandibular Advancement Appliance
This research addresses obstructive sleep apnea syndrome (OSAS), affecting 6-12% of French adults, often treated with mandibular advancement devices (MADs).
- Trial name
- APNEAMOUVE (NCT06576310)
- Testing
- Mandibular Advancement Device
- Where
- France
- Volunteers
- 118 people
- Sponsor
- University Hospital, Toulouse
Blood Pressure
Arterial Properties of Thoracic Aorta Disease
A dissecting or intramural haematoma of the thoracic aorta (AH) is a haemorrhage that dissects the aortic wall. An entry point is detected at an intimal tear, ulcer or plaque rupture via imaging in almost 50% of cases.
- Trial name
- ao_diss (NCT01068691)
- Testing
- Ambulatory blood pressure monitoring (to evaluate the level of blood pressure)
- Where
- France
- Volunteers
- 180 people
- Sponsor
- University Hospital, Grenoble
Obstructive Sleep Apnea, Preoperative Evaluation
Systematic Screening for Obstructive Sleep Apnea During Preoperative Consultation Using AI-preoperative Agents
The goal of this observational study is to evaluate the feasibility of a systematic screening protocol for Obstructive Sleep Apnea (OSA) during preoperative anesthesia consultations in adults aged 50 and older undergoing elective…
- Trial name
- DASCA (NCT06779682)
- Where
- France
- Volunteers
- 150 people
- Sponsor
- Intelligence Anesthesia
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