Clinical trials: Apoplexy; Brain
Cerebral Infarction
Cilostazol Stroke Prevention Study : A Placebo-controlled Double-blind Trial for Secondary Prevention of Cerebral Infarction.
The multi-center, double-blind, placebo-controlled, randomized, group-comparison study was designated to assess the long-term safety and efficacy of the antiplatelet drug cilostazol in preventing the recurrence of cerebral…
- Trial name
- CSPS (NCT00766545)
- Testing
- cilostazol
- Where
- Japan
- Volunteers
- 1,095 people
- Sponsor
- Otsuka Pharmaceutical Co., Ltd.
Stroke
Development of a Tailored Life-Sustaining Treatment Decision Support Intervention for Stroke Surrogate Decision Makers
The trial is testing an investigator-developed decision support tool for surrogate decision makers for stroke patients that are unable to make medical decisions for themselves.
- Trial name
- NCT03427645
- Testing
- Decision tool
- Where
- United States
- Volunteers
- 106 people, healthy volunteers welcome
- Sponsor
- University of Michigan
Atrial Fibrillation, Intracerebral Hemorrhage
PREvention of STroke in Intracerebral haemorrhaGE Survivors With Atrial Fibrillation
Atrial fibrillation (AF) is the most common form of irregular heart rhythm. In people with AF, blood clots often form in the heart, which can travel to the brain.
- Trial name
- PRESTIGE-AF (NCT03996772)
- Testing
- Apixaban Oral Tablet, Dabigatran, Edoxaban Tablets
- Where
- 64 sites in Austria, France and 4 more
- Volunteers
- 319 people
- Sponsor
- Imperial College London
Stroke
Augmented Reality-based Telerehabilitation Platform for Patients With Stroke
The study is to 1) determine the feasibility of the use of our augmented reality (AR) rehabilitation program, including its preliminary efficacy, 2) determine the feasibility of obtaining an augmented reality assessment based on…
- Trial name
- NCT06963645
- Testing
- AR rehabilitation app
- Where
- United States
- Sponsor
- Stanford University
Carotid Artery Diseases, Hypothermia
Body Cooling During Carotid Endarterectomy: No-profit, Open, Mono-centric, Feasibility Study
Aim of the study is to determine whether endovascular systemic cooling to a target temperature of 34-35°C initiated before, and maintained during Carotid EndoArterectomy (CEA), is feasible and safe
- Conditions
- Carotid Artery Diseases, Hypothermia, Stroke, Carotid Artery Plaque
- Trial name
- NCT02629653
- Testing
- endovascular cooling (Zoll system)
- Where
- Italy
- Volunteers
- 10 people
- Sponsor
- S. Andrea Hospital
Stroke
Dose Escalation Upper Limb Rehabilitation in Stroke
A phase 1, single-ascending dose clinical trial will be conducted. This study will be designed to test increasing doses of multimodal exercise in successive cohorts of six participants (cumulative 3 + 3 design)[22] (Figure 1).
- Trial name
- NCT04973553
- Testing
- upper limb rehabilitation
- Where
- Belgium
- Volunteers
- 18 people
- Sponsor
- Hasselt University
Anosognosia, Neglect, Hemispatial
Lesion Site and Neglect Anosognosia in Patients With Left Hemispatial Neglect
The goal of this retrospective is to investigate the relationship between lesion site and neglect anosognosia in subacute or chronic right hemispheric stroke patients with left hemispatial neglect.
- Conditions
- Anosognosia, Neglect, Hemispatial, Stroke, Neurobehavioral Problems
- Trial name
- NCT05654350
- Where
- Turkey (Türkiye)
- Volunteers
- 78 people
- Sponsor
- Gazi University
Stroke, Dysphagia
Effects of CTAR and a Swallowing Pressure Ball in Older Stroke Adults
This study aims to investigate the effectiveness of resistance swallowing rehabilitation using Chin Tuck Against Resistance (CTAR) exercises combined with an innovative swallowing pressure ball in improving swallowing function…
- Conditions
- Stroke, Dysphagia, Post-Stroke Dysphagia
- Trial name
- NCT07620210
- Testing
- Innovative Swallowing Pressure Measurement Ball Combined With CTAR Training, Conventional Swallowing Rehabilitation
- Where
- Taiwan
- Volunteers
- 132 people
- Sponsor
- Chimei Medical Center
Hemianopia, Stroke
Combined tDCS and Vision Restoration Training in Subacute Stroke Rehabilitation: A Pilot Study
The purpose of this Study is to determine whether non-invasive transcranial direct current stimulation (tDCS) is effective in increasing rehabilitation effects after stroke in visual Cortex.
- Trial name
- NCT02935413
- Testing
- tDCS, Standard rehabilitation
- Where
- 2 sites in Austria, Germany
- Volunteers
- 14 people
- Sponsor
- University of Magdeburg
Stroke, Stroke, Ischemic
Bio-Repository of DNA in Stroke: an Epidemiological and Genetic Study
The Bio-Repository of DNA in Stroke (BRAINS) recruits all subtypes of stroke as well as controls from two different continents, Europe and Asia.
- Conditions
- Stroke, Stroke, Ischemic, Stroke Hemorrhagic
- Trial name
- BRAINS (NCT05491824)
- Where
- United Kingdom
- Volunteers
- 7,500 people
- Sponsor
- Royal Holloway University
Stroke
Validity of a New Stroke Dysphagia Screening Tool
Dysphagia or swallowing difficulty is common after stroke occurring in 25-78% of stroke survivors depending on the anatomic location of the stroke and the diagnostic test used.
- Trial name
- NCT01529723
- Where
- United States
- Sponsor
- Rhode Island Hospital
Ischemic Stroke, Acute
Networked Drug REpurposing for Mechanism-based neuroPrOtection in Acute Ischaemic STROKE
A combination therapy proposed to be evaluated in this trial, consisting of three already registered compounds with a validated disease mechanism and with known safety profiles, targets key proteins in the dysregulated signal…
- Trial name
- REPO-STROKE II (NCT05762146)
- Testing
- Riociguat, Propylthiouracil, Perphenazine
- Where
- Germany
- Volunteers
- 28 people
- Sponsor
- Maastricht University
Stroke, Awareness
The Investigation of Public Awareness of Core Stroke Symptoms
To investigate public awareness of core stroke symptoms in more than 40 years old population and its related factors.
- Conditions
- Stroke, Awareness, Health Knowledge, Attitudes, Practice, Core Symptoms
- Trial name
- IPACSS (NCT03167346)
- Where
- China
- Volunteers
- 243,279 people, healthy volunteers welcome
- Sponsor
- Peking Union Medical College Hospital
Ischemic Stroke
Randomized Controlled Trial of Argatroban With Tissue Plasminogen Activator (tPA) for Acute Stroke
Randomized controlled clinical trial to estimate overall treatment benefit (improvement in disability) among stroke patients treated with rt-PA who are randomized to also receive either low-dose Argatroban, high-dose Argatroban…
- Trial name
- ARTSS-2 (NCT01464788)
- Testing
- Low Dose Argatroban, High Dose Argatroban, rt-PA (alteplase)
- Where
- United States
- Volunteers
- 90 people
- Sponsor
- Andrew D. Barreto, MD
Muscle Spasticity, Stroke
Measurements of Displacement Amplitude and Angular Velocities During Passive Extension of the Wrist and Hand Complex in Stroke Patients
The main objective of this monocentric prospective study is to evaluate the amplitudes and angular velocities of extension of the hand and wrist joints during passive mobilization by a physiotherapist in healthy subjects and…
- Trial name
- PHYSIOHAND (NCT04502927)
- Testing
- Passive extension mobilization of the hand and wrist joints
- Where
- France
- Volunteers
- 2 people, healthy volunteers welcome
- Sponsor
- Groupe Hospitalier de la Region de Mulhouse et Sud Alsace
Abdominal Aortic Aneurysm, Coronary Heart Disease NOS
Heart Rate and Initial Presentation of Cardiovascular Diseases (Caliber)
Study of heterogeneity in associations between heart rate and the initial presentation of 12 cardiovascular diseases.
- Conditions
- Abdominal Aortic Aneurysm, Coronary Heart Disease NOS, Unheralded Coronary Death, Intracerebral Haemorrhage
- Trial name
- NCT01947361
- Where
- United Kingdom
- Volunteers
- 1,961,286 people, healthy volunteers welcome
- Sponsor
- University College, London
Cerebrovascular Accident
A Study to Evaluate the Effects of YM872 on Stroke Lesion Volume in Acute Stroke Patients
This study will investigate the effects of a potential neuroprotectant compound, YM872, in the treatment of acute ischemic stroke.
- Trial name
- NCT00044070
- Testing
- YM872 (zonampanel)
- Where
- 89 sites in United States, Austria and 4 more
- Sponsor
- Astellas Pharma Inc
Stroke, Brain Injuries
Neuroprotective Study of Electroacupuncture Pretreatment in Patients Undergoing Cardiac Surgery
The purpose of this study is to evaluate the neuroprotective effect of electroacupuncture pretreatment in patients undergoing cardiac surgery as an preventive sequela in a randomized and controlled clinical trial.
- Trial name
- NCT01020266
- Testing
- non electroacupuncture stimulation, Electroacupuncture pretreatment
- Where
- China
- Volunteers
- 300 people
- Sponsor
- Xijing Hospital
Stroke, Neglect, Hemispatial
Motor Imaging, Neglect, and Upper Extremity Function in Stroke
This study aims to investigate the relationship between motor imagery skills and neglect level, upper extremity motor function, activities of daily living, quality of life, lateralization performance, and mental timer performance…
- Conditions
- Stroke, Neglect, Hemispatial, Motor ımargery, Upper Extremity Function
- Trial name
- NCT07480122
- Testing
- No intervention will be made; an assessment will be conducted.
- Volunteers
- 50 people
- Sponsor
- Inonu University
Stroke, Hemiplegia
Effects of Intermitted Theta Burst Stimulation (iTBS) on Motor Recovery of Upper Extremity in Chronic Stroke Patients
This study aims to evaluate the effects and clinical feasibility of non-invasive brain stimulation protocols, specifically intermittent Theta Burst Stimulation, as part of rehabilitation interventions for motor recovery of upper…
- Conditions
- Stroke, Hemiplegia, Hemiparesis After Stroke, Hand Functionality
- Trial name
- NIMBLE (NCT07073248)
- Testing
- Intermittent Theta Burst Stimulation
- Where
- Sweden
- Volunteers
- 48 people
- Sponsor
- Danderyd Hospital
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