Clinical trials: Apoplexy; Brain
Ischemic Stroke, Transient Ischemic Attack
StAtins in Frail OldEr Patients with Ischemic Stroke or Transient Ischemic Attack - the Randomized Controlled Trial
Two Dutch guidelines (Stroke and Cardiovascular Risk Management) provide conflicting advice on optimal statin treatment in older patients.
- Trial name
- SAFEST - RCT (NCT06785727)
- Testing
- Statin (atorvastatin, fluvastatin, pravastatin, rosuvastatin or simvastatin)
- Volunteers
- 612 people
- Sponsor
- Prof. dr. Nathalie van der Velde
Gait Analysis
An Ankle-foot Orthosis Improves Gait Performance and Satisfaction in Stroke Patients
All participants were at least 6-month post-stroke and had unilateral limb involvement (8 right/4 left). The main inclusion criteria in selection of the participants in this study were as follows :(1) First stroke (2) At least 6…
- Trial name
- NCT03965715
- Testing
- 3D printing AFO, anterior AFO, off-the-shelf AFO
- Where
- Taiwan
- Volunteers
- 20 people
- Sponsor
- National Cheng-Kung University Hospital
Coronary Heart Disease, Angina Pectoris
Safety Study of Kudiezi(Yueanxin,a Chinese Medicine Injection)Used in Hospitals in China
This study was advocated by institute of Basic Research in Clinical Medicine,China Academy of Chinese Medical Sciences in October 2011.
- Conditions
- Coronary Heart Disease, Angina Pectoris, Stroke
- Trial name
- NCT01781676
- Where
- China
- Volunteers
- 30,000 people
- Sponsor
- China Academy of Chinese Medical Sciences
Stroke, Acute
Computer-based Online Database of Acute Stroke Patients for Stroke Management Quality Evaluation
In the past three decades, the burden of stroke has increased in China and has gradually become the leading cause of death. The data acquisition and medical quality management still need to be improved in China.
- Trial name
- NCT04487340
- Testing
- Education
- Where
- China
- Volunteers
- 200,000 people
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Retinal Artery Occlusion, Fibrinolysis
EAGLE - Multicenter Study of the European Assessment Group for Lysis in the Eye
The aim of the EAGLE Study is to compare the efficacy of conservative medical treatment and local intraarterial fibrinolysis in patients with central retinal artery occlusion and to evaluate benefit and risk for the patient of…
- Conditions
- Retinal Artery Occlusion, Fibrinolysis, Visual Acuity, Stroke
- Trial name
- EAGLE (NCT00637468)
- Testing
- Intravenous injection of heparin, Intravenous injection of acetazolamide, Local intra-arterial fibrinolysis
- Where
- 21 sites in Austria, Germany and 1 more
- Volunteers
- 84 people
- Sponsor
- University Hospital Freiburg
Stroke
TReatment Strategy In Acute Ischemic larGE Vessel STROKE: Prioritize Thrombolysis or Endovascular Treatment
Should we prioritize thrombectomy or thrombolysis in acute stroke? Finding the answer to this question will improve treatment and outcome for stroke patients only by changing triage and transportation.
- Trial name
- TRIAGE (NCT03542188)
- Testing
- Primary Stroke Center (PSC), Comprehensive Stroke Center (CSC)
- Where
- Denmark
- Volunteers
- 174 people
- Sponsor
- University of Aarhus
Post-stroke Aphasia
The Effect of PBM on the Electrical Activity of the Brain in Stroke Patients
The Effect of Low-Level Light Therapy on the Electrical Activity of the Brain in Stroke Patients
- Trial name
- PBM (NCT07323823)
- Testing
- photobiomodulation (PBM), control group-receive speech therapy
- Volunteers
- 66 people
- Sponsor
- Pusan National University Yangsan Hospital
Ischemic Stroke
Methanesulfonic Acid Cinepazide Injection for Treatment of Acute Cerebral Infarction
Using placebo as control, The purpose of this study is to evaluate the efficacy and safety of methanesulfonic acid cinepazide injection to relieve disabled degree of acute cerebral infarction patients, and explore the best safe…
- Trial name
- NCT01851759
- Testing
- cinepazide
- Where
- China
- Volunteers
- 288 people
- Sponsor
- Xijing Hospital
Carotid Artery Disease, Carotid Artery Stenoses
Perioperative Argon Inhalation to Improve Neurocognitive Recovery After Carotid Surgery
Currently, over 400,000 reconstructive surgeries on carotid arteries are performed annually worldwide, including carotid endarterectomy (CEA) and carotid stenting.
- Trial name
- NCT07200180
- Testing
- Аrgon-oxygen breathing mixture, Nitrogen-oxygen breathing mixture
- Where
- 2 sites in Russia
- Volunteers
- 100 people
- Sponsor
- Negovsky Reanimatology Research Institute
Ischemic Stroke
Electric Field Navigated 1hz Rtms for Post-stroke Motor Recovery Trial
A prospective, multi-center, randomized, sham-controlled, blinded study combining active Nexstim NBS-guided 1Hz rTMS or sham-rTMS targeting the healthy hemisphere with standardized task oriented rehabilitation will be conducted…
- Trial name
- E-FIT (NCT03010462)
- Testing
- Nexstim NBS guided active rTMS
- Where
- 5 sites in United States
- Volunteers
- 60 people
- Sponsor
- Nexstim Ltd
Atrial Fibrillation
Early Atrial Fibrillation Ablation for Stroke Prevention in Patients With High Comorbidity Burden (EASThigh-AFNET 11)
EASThigh-AFNET 11 is an international, prospective, randomized, open, blinded endpoint assessment, multicenter trial (Treatment Strategy trial).
- Trial name
- NCT06324188
- Testing
- Early atrial fibrillation ablation, Usual Care
- Where
- 7 sites in Australia, Canada and 5 more
- Volunteers
- 2,312 people
- Sponsor
- Atrial Fibrillation Network
Beta-Thalassemia Trait, Coronary Artery Disease
B-Thalasaemia Trait and Its Possible Cardioprotective Role
Our purpose is to investigate whether thallasaemia trait offers protection against cardiovascular events and whether this can be applied to specific characteristics of these people ( better lipid profile , better blood pressure…
- Trial name
- NCT02428023
- Where
- Greece
- Volunteers
- 2,500 people, healthy volunteers welcome
- Sponsor
- 404 General Military Hospital, Larissa
Cerebrovascular Event, Acute Ischemic Stroke
Prospective Italian Validation of SMS in Patients With Suspected Acute Stroke
The overall objective of the study is to prospectively validate the diagnostic accuracy of the Stroke Mimics Score (SMS). This score is calculated using information collected at the time of the patient's arrival in the Emergency…
- Conditions
- Cerebrovascular Event, Acute Ischemic Stroke, Intracerebral Hemorrhage, TIA (Transient Ischemic Attack)
- Trial name
- PIVA-SMS (NCT07601659)
- Volunteers
- 1,000 people
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Stroke
The Effects of Thoracic Joint Mobilization on Pulmonary Functions of Patients With Stroke
Stroke a neurological disorder leads to long term disability and decline in overall quality of life. Pulmonary Functions are usually impaired in individuals with stroke.
- Trial name
- NCT04188496
- Testing
- Pulmonary Function Test group, Control Group
- Where
- Pakistan
- Volunteers
- 26 people
- Sponsor
- Shehla Gul
Stroke, Multiple Sclerosis
Development and Application of Tele-Neuro Rehabilitation System
Disability due to neurological diseases is increasing in our country and world. With regular physiotherapy and rehabilitation, as well as patients' symptoms are brought under control, their affected functions in daily life are…
- Conditions
- Stroke, Multiple Sclerosis, Parkinson Disease
- Trial name
- NCT05031403
- Testing
- Telerehabilitaton, Home Exercise
- Where
- Turkey (Türkiye)
- Volunteers
- 114 people
- Sponsor
- Istanbul University - Cerrahpasa
Cerebrovascular Stroke
Sub-Acute Stroke Rehabilitation With AMES
The AMES device is designed to produce functional cortical changes by:(1) assisting the subject as he/she attempts to move the limb (assisted movement) and (2) enhancing movement sensation by vibrating the muscles during movement…
- Trial name
- AMES (NCT00609115)
- Testing
- AMES device (test), AMES device (crossover)
- Where
- 5 sites in United States
- Volunteers
- 83 people
- Sponsor
- AMES Technology
High Blood Pressure, Stroke
Innovative Tools to Expand Music-Inspired Strategies for Blood Pressure and Stroke Prevention
Expanding evidence-based interventions for hypertension and stroke prevention among youth and their caregivers is crucial for meeting World Health Organization and Nigerian health goals.
- Trial name
- ITEST-BPStroke (NCT07386535)
- Testing
- Music4Health Intervention
- Where
- Nigeria
- Volunteers
- 1,412 people, healthy volunteers welcome
- Sponsor
- Washington University School of Medicine
Stroke, Ischemic, Smartpose
The Effect of Rehabilitative Games With SmartPose on Upper Extremity Recovery in Stroke Patients
The goal of this clinical trial is to investigate the effects of SmartPose games on upper extremity motor, functional, and sensory recovery in patients with stroke.
- Conditions
- Stroke, Ischemic, Smartpose, Telerehabilitation
- Trial name
- NCT06778525
- Testing
- Exercise, SmartPose
- Where
- Turkey (Türkiye)
- Volunteers
- 34 people
- Sponsor
- Istanbul University - Cerrahpasa
Stroke, Subluxation, Glenohumeral
Kinesiotaping Effect Glenohumeral Shoulder Subluxation
To evaluate the effectiveness of the kinesiotaping on pain, recovery of movement and daily life activities in Turkish hemiplegic patients.
- Trial name
- NCT04468750
- Testing
- kinesiotape
- Volunteers
- 14 people
- Sponsor
- Ankara Physical Medicine and Rehabilitation Education and Research Hospital
Stroke
Assessment of the WATCHMAN™ Device in Patients Unsuitable for Oral Anticoagulation
The purpose of this study is to establish the safety and effectiveness of the WATCHMAN™ Left Atrial Appendage Closure (LAAC) Device, including the post-implant medication regimen, for subjects with non-valvular atrial…
- Trial name
- ASAP-TOO (NCT02928497)
- Testing
- WATCHMAN LAAC Device Implant, Single Antiplatelet Therapy or No Therapy (Control)
- Where
- 92 sites in United States, Belgium and 7 more
- Volunteers
- 481 people
- Sponsor
- Boston Scientific Corporation
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