Clinical trials: Appendectomy
Laparoscopic Surgery, Acute Appendicitis With Rupture
Open to Laparoscopic Reverse Conversion of Perforated Appendicitis
A Prospective Randomized Controlled Trial of Reverse Conversion (Open to Laparoscopic) in management of Acute Perforated Appendicitis
- Conditions
- Laparoscopic Surgery, Acute Appendicitis With Rupture, Sepsis, Abdominal Abscess
- Trial name
- reverse (NCT05283733)
- Testing
- reverse conversion technique
- Where
- Egypt
- Volunteers
- 426 people
- Sponsor
- Zagazig University
Appendicitis
Safety and Efficacy Study of Single Port Laparoscopic Appendectomy in Acute Appendicitis
The aim of this study is to investigate the safety and efficacy of single port laparoscopic appendectomy compared with conventional laparoscopic appendectomy in adults with acute appendicitis.
- Trial name
- NCT01007318
- Testing
- Single port laparoscopic appendectomy, 3 port laparoscopic appendectomy
- Where
- South Korea
- Volunteers
- 194 people
- Sponsor
- Kyunghee University Medical Center
Appendicitis
Single Incision Versus Conventional Laparoscopic Appendectomy
The aim of this study is to compare the short-term outcomes of single-incision and conventional laparoscopic appendectomy.
- Trial name
- NCT01515293
- Testing
- Single Incision Laparoscopic Appendectomy, Conventional appendectomy
- Volunteers
- 184 people
- Sponsor
- Hospital Universitario Virgen de la Arrixaca
Acute Uncomplicated Appendicitis
Pilot Trial of Antibiotics Versus Surgery for Treating Acute Appendicitis
The major goal of the project is to demonstrate the feasibility of conducting a multi-center randomized clinical trial of antibiotic therapy versus appendectomy for the treatment of patients with acute uncomplicated appendicitis…
- Trial name
- NCT02447224
- Testing
- 1 gm IV ertapenem at enrollment, 1 gm IV ertapenem at Day 2 and oral metronidazole and cefdinir to complete 10 days, Appendectomy
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Olive View-UCLA Education & Research Institute
Appendicitis Acute
Comparison of Open and Laparoscopic Appendectomy in Pediatric Population
Introduction: In the era of minimally invasive surgery, changing trends are towards laparoscopic surgery, first introduced in 1983.
- Trial name
- Appendicitis (NCT06363318)
- Testing
- Laparoscopic appendicectomy
- Where
- Pakistan
- Volunteers
- 100 people
- Sponsor
- King Edward Medical University
Appendicitis
The Hospital Volume Relationship in Appendicectomy Outcomes
Background Appendicitis is a common condition which represents a significant resource burden for the Scottish National Health Service (NHS).
- Trial name
- NCT02018016
- Where
- United Kingdom
- Volunteers
- 40,000 people
- Sponsor
- University of Edinburgh
Appendicitis
Non Absorbable Clips vs Endoloops in Laproscopic Appendicectomy
a) Compare between Nonabsorbable Polymeric Clips and Endoloop ligatures regarding: 1. technical difficulties. 2. operation time. 3. cost effectiveness. 4. postoperative complications. 5. inpatient stay.
- Trial name
- NCT04094480
- Testing
- polymeric non absorbable clips, endoloops
- Volunteers
- 40 people
- Sponsor
- Assiut University
Post Operative Pain, Laparoscopic Surgery
Modified Thoracoabdominal Nerve Block(M-TAPA) in Pediatric Laparoscopic Appendectomies
To compare the effect of M-TAPA block and port-site local anesthetic infiltration on postoperative pain in pediatric laparoscopic appendectomies.
- Conditions
- Post Operative Pain, Laparoscopic Surgery, Pediatrics, Regional Anesthesia
- Trial name
- M-TAPA (NCT06039150)
- Testing
- M-TAPA Block, Local anesthetic infltration to port sites
- Where
- Turkey (Türkiye)
- Volunteers
- 52 people
- Sponsor
- Gulhane Training and Research Hospital
Appendicitis Acute, Appendicitis Perforated
Enhanced Recovery After Surgery (ERAS) for Complicated Appendicitis
The exploratory objective of this pilot study is to evaluate the feasibility and safety of an enhanced recovery protocol that will allow adult patients to be discharged to home on an oral antibiotic regimen for three days…
- Conditions
- Appendicitis Acute, Appendicitis Perforated, Appendicitis With Perforation, Appendicitis Suppurative
- Trial name
- NCT06948071
- Testing
- Discharge on oral antibiotics
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Cedars-Sinai Medical Center
Acute Appendicitis
Laparoscopic Appendectomy by Multi-port vs Single Port.
Laparoscopic appendectomy (LA) is nowadays considered the gold standard in fertile women affected by uncomplicated appendicitis. The level of evidence for benefits from LA in this subgroup is high.
- Trial name
- AMUSING (NCT01720082)
- Testing
- Single incision laparoscopic appendectomy, Multiport laparoscopic appendectomy
- Where
- Italy
- Volunteers
- 300 people
- Sponsor
- Associazione Chirurghi Ospedalieri Italiani
Morbid Obesity, Hernia
Minimally Invasive Surgery (MIS) Database for the Purpose of Research
The Minimally Invasive Surgery Team (MIST) are establishing a separate research database to find out more about patient's undergoing minimally invasive surgery (laparoscopic , open and robot assisted) procedures at UCSD.
- Conditions
- Morbid Obesity, Hernia, Colorectal Cancer, Laparoscopy
- Trial name
- NCT00535990
- Where
- United States
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- University of California, San Diego
Appendicitis, Chronic Post-Procedural Pain
Pain and Discomfort After Appendectomy in Children
Appendectomy is the most common surgical procedure. Chronic abdominal pain is an uncommon complication following appendectomy. It is observed that pediatric patients who have undergone abdominal surgical procedure complained of…
- Trial name
- NCT03791229
- Where
- Turkey (Türkiye)
- Volunteers
- 120 people
- Sponsor
- Sakarya University
Reduce Pain After Appendectomy
Paravertebral Block for Pain Management After Appendectomy
Paravertebral Block (PVB) was shown to be a successful and useful technique of anesthesia and analgesia. Its effect was evident in thoracic and abdominal surgeries.
- Trial name
- NCT03189693
- Testing
- PVB, GA, Anesthetic injections
- Where
- Lebanon
- Volunteers
- 60 people
- Sponsor
- Makassed General Hospital
Post Operative Pain, Appendicitis
Evaluation of Local Anesthetic at Incision Site
Patient will have usual appendectomy surgery with an injection of local or saline at incision site either before or after the incision at random.
- Trial name
- NCT02483689
- Testing
- Pre Incisional Local Anesthetic, Pre-Incisional Saline, Post-Closure Local Anesthetic
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Valley Anesthesiology Consultants
Post Operative Pain, Appendicitis Acute
Transversus Abdominis Plane Block Versus Quadratus Lumborum Block for Pain Management in Laparoscopic Appendectomy
Laparoscopic appendectomy causes postoperative pain. The primary objective of this prospective randomized controlled study is to compare the effect of ultrasound (US)-guided quadratus lumborum block (QLB) on 24-hour cumulative…
- Conditions
- Post Operative Pain, Appendicitis Acute, Surgery
- Trial name
- NCT05310266
- Testing
- Transversus abdominis plane block, Quadratus Lumborum Block
- Where
- Turkey (Türkiye)
- Volunteers
- 168 people
- Sponsor
- Bakirkoy Dr. Sadi Konuk Research and Training Hospital
Appendicitis
Comparative Study of Harmonic Scalpel vs. Suture Ligation for Appendix Base During Laparoscopic Appendectomy
This study is a comparative study between use of suture ligation vs harmonic scalpel for sealing and cutting the base of appendix.
- Trial name
- HASSEL (NCT07049965)
- Testing
- Suture ligation, Harmonic Scalpel
- Where
- India
- Volunteers
- 60 people
- Sponsor
- GSVM Medical College
Appendicitis
Same Day Ambulatory Appendectomy (SAMBA)
The potential benefit of outpatient care for this common digestive emergency is considerable, both for the patients themselves and for the public health system: 1.
- Trial name
- SAMBA (NCT05691348)
- Testing
- Ambulatory appendectomy, Conventional appendectomy
- Where
- 33 sites in France, Reunion
- Volunteers
- 1,400 people
- Sponsor
- Centre Hospitalier Universitaire de Nice
Appendicitis, Cholelithiasis
Single Incision Laparoscopy
Laparoscopic surgery being performed with only one small incision via the umbilicus (belly button).
- Conditions
- Appendicitis, Cholelithiasis, Malignant Hypertension
- Trial name
- SIL (NCT00616616)
- Testing
- single incision laparoscopic surgery
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- University of California, San Diego
Acute Appendicitis, Appendicitis (Diagnosis)
Laparoscopic vs Open Appendectomy in Obese Patients
Acute appendicitis is one of the most common surgical emergencies globally. While surgical removal of the appendix (appendectomy) is the definitive treatment, the optimal surgical approach-laparoscopic versus open-remains widely…
- Conditions
- Acute Appendicitis, Appendicitis (Diagnosis), Obesity
- Trial name
- NCT07822503
- Testing
- Open Appendectomy, Laparoscopic Appendectomy
- Volunteers
- 166 people
- Sponsor
- University of Health Sciences Lahore
Appendicitis Acute
Investigation of Oxidative Stress in Appendectomy - Open Versus Laparoscopic in Childhood and Adolescence
In the planned prospective randomized study, oxidative stress will be investigated by analyzing volatile organic compounds in the exhaled air in children.
- Trial name
- OSAE (NCT03723642)
- Testing
- Initial serum malondialdehyde level, Final serum malondialdehyde level, Initial differential white blood cell count
- Where
- Austria
- Volunteers
- 40 people
- Sponsor
- Medical University of Graz