Clinical trials: Appendicitis (Diagnosis)
Appendectomy, Laparoscopic, Intra Abdominal Pressure
Laparoscopic Appendectomy: Outcomes of 10 mmHg Versus 15 mmHg Intra-abdominal Pressure
This prospective, randomized controlled trial aims to compare the clinical outcomes of laparoscopic appendectomy performed under two standard pneumoperitoneum pressures (10 mmHg and 15 mmHg).
- Trial name
- NCT07727499
- Testing
- Laparoscopic appendectomy with 10 mmHg pneumoperitoneum, Laparoscopic appendectomy with 15 mmHg pneumoperitoneum
- Where
- Turkey (Türkiye)
- Volunteers
- 150 people
- Sponsor
- Ankara Etlik City Hospital
Diagnosis of Acute Appendicitis in Children
Urinary 5-HIAA for Diagnosis of Acute Appendicitis in Children, Does it Help?
it is randomized control study. two groups of children (n=191) were divided into two groups A and B. Group A included children subjected to the classical protocol of diagnosis of acute appendicitis.
- Trial name
- NCT04527263
- Testing
- measurement of urinary 5-HIAA
- Where
- Egypt
- Volunteers
- 191 people
- Sponsor
- Tanta University
Acute Appendicitis in Elderly
Clinicopathological Aspects of Acute Appendicitis in Patients Above Age of Thirty at Sulaimani Emergency Hospital
Aims of this study are : Estimate the incidence of A.A. in patients above age of 30 y in 4 age groups . Correlate between different clinical aspects and histopathological results.
- Trial name
- NCT04033198
- Testing
- Appendectomy
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- University of Sulaimani
Appendicitis
Conservative Versus Operative ManageMent of Acute Uncomplicated Appendicitis
This study aims to compare antibiotic treatment versus surgery for patients with uncomplicated appendicitis.
- Trial name
- COMMA (NCT02916134)
- Testing
- Laparoscopic +/- Open Appendicectomy, Antibiotic treatment
- Where
- Ireland
- Volunteers
- 186 people
- Sponsor
- Beaumont Hospital
Appendicitis
Low vs. Standard Dose CT for Appendicitis Trial
To determine whether low-dose (LD) CT is noninferior to standard-dose (SD) computed tomography (CT) as the first-line imaging test in adolescents and young adults in regard to negative appendectomy rate (NAR).
- Trial name
- LOCAT (NCT01925014)
- Testing
- Diagnostic CT with low-dose radiation, Diagnostic CT with standard-dose radiation
- Where
- 20 sites in South Korea
- Volunteers
- 3,074 people
- Sponsor
- Kyoung Ho Lee, MD
Appendicitis
Peri-operative Analgesia for Single-incision Laparoscopic Appendectomy
Laparoscopic appendectomy is a very common intervention in pediatric surgery. To improve outcomes, some teams have developed the use of single-site laparoscopic appendectomy (SILAP).
- Trial name
- PAMAL (NCT05773521)
- Testing
- SILAP (single incision laparoscopic appendectomy)
- Where
- France
- Volunteers
- 140 people
- Sponsor
- University Hospital, Angers
Perforated Appendicitis
Irrigation Versus No Irrigation for Perforated Appendicitis
The purpose is to quantify the effect of irrigation during laparoscopic appendectomy for perforated appendicitis.
- Trial name
- NCT00854815
- Testing
- Irrigation, No Irrigation
- Where
- United States
- Volunteers
- 220 people
- Sponsor
- Children's Mercy Hospital Kansas City
Appendicitis Acute
Laparoscopic Versus Open Appendectomy Prospective Randomized Control Study
laparoscopic versus open appendectomy prospective randomized control study.Both surgical methods are safe and well established in clinical practice but there has been a controversy about which surgical procedure is the most…
- Trial name
- NCT05611489
- Testing
- Open appendectomy, Conventional Lap appendectomy
- Volunteers
- 70 people
- Sponsor
- Abanoub Atif Fawzy
Appendicitis Acute, Disbiosis
Differences In Microbiota Profiles Of Pediatric Appendicitis Cases
The microbial profile varies between simple appendicitis (SA) and complicated appendicitis (CA) cases. An appendectomy has been noted to temporarily diminish gut bacterial diversity.
- Conditions
- Appendicitis Acute, Disbiosis, Complicated Appendicitis, Simple Appandiscitis
- Trial name
- NCT07860307
- Testing
- Appendectomy
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Istanbul University
Appendicitis
Is Interval Appendectomy Necessary?
Appendicitis is one of the most common surgical problems in children, with 20-35% of patients having perforated by the time they present to a doctor. In these cases, the patient is often treated non-surgically with antibiotics.
- Trial name
- NCT01853683
- Testing
- Conservative Management, Operative Management
- Where
- Canada
- Volunteers
- 5 people
- Sponsor
- Children's Hospital of Eastern Ontario
Appendicitis
Emergency Department CT Scanning for Appendicitis
The purpose of this study is to compare IV contrast only vs. IV and oral contrast Computed Tomography (CT) for the diagnosis of acute appendicitis in adult patients in our emergency department.
- Trial name
- NCT00734825
- Testing
- Omnipaque
- Volunteers
- 244 people
- Sponsor
- WellSpan Health
Appendicitis Acute
Evaluation of One Day Discharge After Laparoscopic Appendectomy for Uncomplicated Appendicitis in Children.
The aim of this study was to evaluate the value and safety of discharge of a child to home care within 24 hours after laparoscopic appendectomy for uncomplicated appendicitis to reduce the impact on the child's psyche and need…
- Trial name
- NCT05095987
- Testing
- Laparoscopic Appendectomy
- Where
- Croatia
- Volunteers
- 180 people
- Sponsor
- Miro Jukić
Appendicitis Surgery
Complex And Simple Appendicitis: REstrictive or Liberal Post-operative Antibiotic eXposure (CASA RELAX) - Atrium Health
To demonstrate the safety, efficacy, and feasibility of short-course post-operative antibiotic treatment for simple and complicated appendicitis
- Trial name
- NCT05746520
- Testing
- Antibiotic
- Where
- United States
- Volunteers
- 268 people
- Sponsor
- Wake Forest University Health Sciences
Abscess, Intra-Abdominal, Cholecystitis
Cefoperazone/Sulbactam In The Treatment Of Serious Intra-Abdominal And Hepatobiliary Infections.
The primary objective is to collect data on treatment outcomes (clinical and microbiological cure), safety and tolerability of treatment with cefoperazone/sulbactam in patients with serious intra-abdominal and hepatobiliary…
- Conditions
- Abscess, Intra-Abdominal, Cholecystitis, Wound Infections, Peritonitis
- Trial name
- NCT00463762
- Testing
- CP-75385-02 Cefoperazone/sulbactam
- Sponsor
- Pfizer
Acute Appendicitis
Diffusion MRI in Appendicitis
In this study, it was aimed to investigate the effect of diffusion-weighted magnetic resonance imaging on diagnosis and surgical decision in patients with suspected acute appendicitis.
- Trial name
- NCT04518436
- Where
- Turkey (Türkiye)
- Volunteers
- 164 people
- Sponsor
- Yuksek Ihtisas University
Appendicitis
Appendicectomy Skin Closure Technique: Changing Paradigms (ASC)
To compare the results associated with two different skin closure techniques in open appendectomy. 200 patients were included after acute appendicitis diagnosis in emergency department.
- Trial name
- ASC (NCT02625987)
- Testing
- Continuous intradermic stitch, Separated stitches
- Volunteers
- 200 people
- Sponsor
- María Valeria Jiménez Baez
Opioid Consumption, Multimodal Analgesia
Magnesium Sulfate in Children Undergoing Laparoscopic Appendectomy
Magnesium sulfate is one of the most commonly used co-analgetics. Its antinociceptive effect is related to antagonizing NMDA (N-methyl-D-aspartate) receptors of the nervous system, has an anti-inflammatory effect by reducing the…
- Conditions
- Opioid Consumption, Multimodal Analgesia, Acute Appendicitis, Complication of Treatment
- Trial name
- NCT06563349
- Testing
- Intravenous magnesium sulfate, Normal saline infusion
- Where
- Poland
- Volunteers
- 188 people
- Sponsor
- Medical University of Warsaw
Appendicitis
Laparoscopic Appendectomy for Uncomplicated Appendicitis: Does Antimicrobial Prophylaxis Really Matter?
To compare surgical site infection (SSI) rate in patients undergoing laparoscopic appendectomy for acute uncomplicated appendicitis and treated with single dose regime of antibiotics versus group of patients undergoing…
- Trial name
- NCT02404064
- Testing
- cefamezin 1g IV, metronidazole 500 mg IV
- Volunteers
- 288 people
- Sponsor
- HaEmek Medical Center, Israel
Acute Appendicitis
Optimizing the Diagnosis of Acute Appendicitis
Aim of the study: to identify the signs of acute appendicitis delta signs - clinical, laboratory or ultrasound signs, whose change (delta) would allow to identify or deny the diagnosis of acute appendicitis without a computed…
- Trial name
- OPTIMA (NCT04117061)
- Testing
- Observation
- Where
- Lithuania
- Volunteers
- 200 people
- Sponsor
- Vilnius University
Appendicitis, Perforated Appendicitis
Optimal Care of Complicated Appendicitis
When the appendix becomes infected and inflamed, it is called appendicitis. Sometimes, if the infection and inflammation get worse, the appendix can die or burst, leading to a larger infection or even pus pockets around the…
- Conditions
- Appendicitis, Perforated Appendicitis, Ruptured Appendicitis, Complicated Appendicitis
- Trial name
- NCT03159754
- Testing
- Early Appendectomy, Interval Appendectomy, Antibiotics
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- University of Michigan