Clinical trials: Appendicitis (Diagnosis)
Appendicitis
Transvaginal Appendectomy
The purpose of this study is to determine the feasibility and safety of transvaginal appendectomy and determine and compare the postoperative pain and quality of life after surgery to standard laparoscopic transabdominal…
- Trial name
- NCT00806429
- Testing
- transvaginal appendectomy
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Yale University
Appendicitis Acute
Imaging and Histopathological Examination for Evaluation of Pediatric Appendicitis Score
Appendicitis is the most common abdominal disease requiring surgery in children. The risk of developing appendicitis during a lifetime is reported to be 8.7% for boys and 6.7% for girls.
- Trial name
- NCT03171662
- Testing
- Evaluation of Pediatric Appendicitis Score
- Volunteers
- 75 people
- Sponsor
- Assiut University
Uncomplicated Acute Appendicitis
Clinical Pathway With "Fast-Track" In Uncomplicated Acute Appendicitis
The aim of this study is to reduce the postoperative hospital stay, without increasing morbidity and mortality postoperative, expressed in terms of rate of complications and readmissions.
- Trial name
- CLIPUA (NCT02326415)
- Testing
- Clinical Pathway with "Fast-Track", Postoperative Usual Protocol
- Where
- Spain
- Volunteers
- 300 people
- Sponsor
- Hospital Universitario Virgen de la Arrixaca
Appendicitis
Evaluation of the Management of Acute Appendicitis Before Emergency Department in Children: a Prospective Study
Acute appendicitis is the first visceral surgical emergency in pediatrics with about 30,000 cases in children having been described in France.
- Trial name
- NCT04885335
- Testing
- PAS (Pediatric Appendicitis Score) survey
- Where
- France
- Volunteers
- 11 people
- Sponsor
- University Hospital, Limoges
Appendicitis Acute, Safety Issues
Review of Efficacy of Used ultraSonic Energy Device
Single-use medical instruments are intended by the manufacturers for single-use only or for single-patient-use only. Nevertheless, single-use instruments are being reused more than once in many countries around the world.
- Conditions
- Appendicitis Acute, Safety Issues, Complication of Surgical Procedure, Device Induced Injury
- Trial name
- REUSED (NCT04226482)
- Testing
- New Device, Used Device
- Where
- 2 sites in Croatia
- Volunteers
- 100 people
- Sponsor
- University of Split, School of Medicine
Appendicitis
Practical Advantages of Single-port Over Three-port Laparoscopic Appendectomy in Children
Despite growing popularity, practical advantages of single-port laparoscopic appendectomy (SLA) over conventional three-port laparoscopic appendectomy (CLA) have yet to be established well in pediatric population.
- Trial name
- PASTA (NCT03106467)
- Testing
- Single-port laparoscopic appendectomy, Three-port laparoscopic appendectomy
- Where
- South Korea
- Volunteers
- 400 people
- Sponsor
- Hallym University Medical Center
Appendicitis Acute
Value of Ultrasound and Computed Tomography in the Diagnosis of Acute Appendicitis With Histopathology as Gold Standard.
This study is a retrospective evaluation of all patients treated surgically for appendicitis over a period of 3 years at the Sint- Andries Hospital, Tielt. Belgium.
- Trial name
- NCT05070000
- Testing
- Radiologic examination
- Volunteers
- 304 people
- Sponsor
- KU Leuven
Appendicitis, Abdominal Abscess
Laparoscopic Management of Periappendicular Abscess
According to retrospective studies the conservative management of periappendicular abscess is associated with decreased complication and re-operation rate compared with open appendectomy.
- Trial name
- NCT01283815
- Testing
- Laparoscopic appendectomy, Conservative management with percutaneous drainage
- Where
- Finland
- Volunteers
- 60 people
- Sponsor
- Helsinki University Central Hospital
Appendicitis, Gastroenteritis
Study on the Difference of Axilo-rectal Temperature in Appendicitis
The investigators are studying prospectively the difference in axilo-rectal temperature in patients with acute appendicitis and using as a control group patients consulting with acute gastroenteritis at our emergency unit.
- Trial name
- NCT00674726
- Testing
- Observation and measurement of axilo-rectal temperature
- Where
- 2 sites in Chile
- Sponsor
- Cirujanos la Serena
Gangrenous Appendicitis
Prophylaxis With Single Versus Five Dose of Antibiotic Therapy as Treatment of Patients With Gangrenous Acute Appendicitis
A prospective, randomized controlled clinical trial was conducted at the Hospital Universitario de Santander to test the effectiveness of providing a single 1-dose therapy of antibiotic prophylaxis versus a 5-day antibiotic…
- Trial name
- NCT01115153
- Testing
- prophylaxis, therapy
- Where
- Colombia
- Volunteers
- 150 people
- Sponsor
- Universidad Industrial de Santander
Appendicitis
Geographic Influences on Appendicectomy Outcomes
Introduction Appendicitis is a common condition which represents a significant resource burden for the Scottish National Health Service (NHS).
- Trial name
- NCT02017951
- Where
- United Kingdom
- Volunteers
- 40,000 people
- Sponsor
- University of Edinburgh
Acute Appendicitis
The Role of Contrast Enhanced Ultrasound in Appendicitis
This study seeks to determine the efficacy of Contrast Enhanced Ultrasound (CEUS) in improving the diagnosis of acute appendicitis in children, when compared to the standard grey-scale ultrasound.
- Trial name
- NCT03687502
- Testing
- Sulfur hexafluoride lipid-type A microspheres
- Where
- United States
- Volunteers
- 37 people
- Sponsor
- Children's Mercy Hospital Kansas City
Acute Appendicitis, Abdominal Pain (AP)
Preserving or Resecting the Normal Appendix in Patients Undergoing Laparoscopy Surgery for Suspected Appendicitis
When appendicitis is suspected, patients are typically planned for emergency surgery preferably using a laparoscopic approach. Up to 20% of these patients will have a normal appendix, thus not suffering from appendicitis.
- Conditions
- Acute Appendicitis, Abdominal Pain (AP), Diagnostic Laparoscopy, Laparoscopic Appendectomy
- Trial name
- NCT06917612
- Testing
- Normal diagnostic laparoscopy, Negative appendectomy
- Volunteers
- 20,000 people
- Sponsor
- Herlev Hospital
Appendicitis, Appendectomy
A Global Prospective Cohort Study on Outcomes of Appendicectomy for Appendicitis
This study aims to assess and improve the global management of appendicitis, the most common emergency surgery, by examining various aspects of emergency care systems worldwide.
- Trial name
- AlliGatOr (NCT06774001)
- Testing
- Appendicectomy
- Where
- 7 sites in Benin, Ghana and 5 more
- Volunteers
- 14,000 people
- Sponsor
- University of Birmingham
Appendicitis, Abdominal Pain
The Value of Pancreatic Stone Protein in Predicting Acute Appendicitis
PSP (Pancreatic Stone Protein) is a compound naturally produced mainly in the pancreas and the gut. There is evidence from experimental and clinical trials that the levels of PSP in the blood rise in the presence of inflammation…
- Conditions
- Appendicitis, Abdominal Pain, Abdominal Sepsis
- Trial name
- NCT01610193
- Testing
- Appendicectomy
- Where
- 2 sites in Switzerland
- Volunteers
- 245 people
- Sponsor
- University of Zurich
Perforated Appendicitis, Covid19
Frequency of Perforated Appendicitis in Times of COVID-19
Appendicitis is one of the most common clinical conditions in general surgery. The diagnosis is usually made from clinical examination, imaging (sonography or CT) and laboratory parameters.
- Trial name
- NCT04472052
- Testing
- appendectomy
- Where
- Germany
- Volunteers
- 143 people
- Sponsor
- University Hospital Tuebingen
Appendix Abscess, Appendicitis
The Prevalence of Appendiceal Tumours in Periappendicular Abscess
Complicated and uncomplicated appendicitis follow different epidemiological trends also suggesting different pathophysiology behind these two different forms of appendicitis.
- Conditions
- Appendix Abscess, Appendicitis, Appendix Mass, Appendix Cancer
- Trial name
- PeriAPPAC-T (NCT04634448)
- Testing
- Interval appendectomy, Follow-up MRI at 1 year
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Turku University Hospital
Chronic or Recurrent Appendicitis
Laparoscopic Appendectomy for Chronic Right Lower Abdominal Pain
It is questionable whether elective appendectomy can effectively reduce pain in persistent or recurrent lower abdominal quadrant pain due to chronic appendicitis.
- Trial name
- NCT00413855
- Testing
- laparoscopic appendectomy or not (surgery)
- Volunteers
- 40 people
- Sponsor
- Maxima Medical Center
Acute Appendicitis, Acute Abdomen
Transversus Abdominis Plane Block in Acute Appendicitis Pain Managment
In this study, it was aimed to investigate the analgesic efficacy of the preoperatively applied Transversus Abdominis Plane (TAP) Block in the management of acute appendicitis-related abdominal pain and post-appendectomy pain.
- Conditions
- Acute Appendicitis, Acute Abdomen, Postoperative Pain
- Trial name
- NCT05004532
- Volunteers
- 22 people
- Sponsor
- Erol Olcok Corum Training and Research Hospital
Gastric Ulcer With Perforation But Without Obstruction, Colon Cancer
Domestic Surgical Robot Clinical Study
Central South University in collaboration with Tianjin University developed the first domestically produced Chinese minimally invasive surgical (MIS) robot system which named "Micro Hand S" in 2013.
- Conditions
- Gastric Ulcer With Perforation But Without Obstruction, Colon Cancer, Cholecystolithiasis, Appendicitis
- Trial name
- NCT02752698
- Testing
- Micro Hand S robotic surgery, laparoscopic surgery, da Vinci robotic surgery
- Where
- China
- Volunteers
- 200 people
- Sponsor
- The Third Xiangya Hospital of Central South University