Clinical trials: Appendicitis (Diagnosis)
Acute Appendicitis
Preoperative Immature Granulocyte Count and Percentage for Acute Appendisitis
Appendectomy is the most effective treatment option for acute appendisitis, which is the most commen emergent surgical pathology. However with in time period, surgical treatment borders are narrowed.
- Trial name
- NCT04440150
- Testing
- Appendectomy
- Where
- Turkey (Türkiye)
- Volunteers
- 70 people
- Sponsor
- Kahramanmaras Sutcu Imam University
Appendicitis, Postoperative Pain
Comparison of Outcome of Open Appendectomy With and Without Transversus Abdominis Plane (TAP) Block
This study is being conducted to compare two types of pain management techniques in patients undergoing open appendectomy (surgical removal of the appendix through a traditional incision).
- Trial name
- NCT06943456
- Testing
- Transversus Abdominis Plane (TAP) Block for Postoperative Pain Management, Standard Open Appendectomy with Postoperative Pain Management
- Volunteers
- 136 people
- Sponsor
- University of Health Sciences Lahore
To Report the Rare Occurrence of Meckel's Diverticulum
The Uncommon Complications of Meckel's Diverticulum
Acas series study was conducted on emergency acute abdomen patients who finally confirmed intraoperatively as Meckel's diverticulum with different complications.
- Trial name
- MD (NCT05793385)
- Testing
- operative intervention
- Where
- Ethiopia
- Volunteers
- 4 people
- Sponsor
- Haramaya Unversity
Parkinson's Disease, Chronic Appendicitis
A Study Assessing the Effects of Acupuncture in Parkinson's Disease Patients With Chronic Appendicitis
The incidence of PD is high, and when the disease is serious to a certain extent, the effect of drugs to control symptoms decreases, resulting in a significant reduction in the quality of life of patients.
- Conditions
- Parkinson's Disease, Chronic Appendicitis, Acupuncture
- Trial name
- NCT06304285
- Testing
- Acupuncture treatment
- Where
- China
- Volunteers
- 84 people
- Sponsor
- The First Affiliated Hospital of University of Science and Technology of China
Acute Appendicitis, Acute Appendicitis With Rupture
Validation and Comparison of the Appendicitis Inflammatory Response Score and Adult Appendicitis Score
Acute appendicitis is one of the most frequent reasons of emergency laparotomy in adults. Symptoms of acute appendicitis overlap with other clinical conditions and might present as a challenge, especially in the early phases.
- Trial name
- NCT04730752
- Testing
- Appendicitis Inflammatory Response, Adult Appendicitis Score
- Where
- Turkey (Türkiye)
- Volunteers
- 174 people
- Sponsor
- Nigde Omer Halisdemir University
Acute Appendicitis
Single-incision Laparoscopic Surgery in Acute Abdomen
Since Semm et.al. reported the first case of laparoscopic appendectomy in 1983, minimally invasive surgery has become the main stay for treating of many surgical diseases.
- Trial name
- NCT03198065
- Testing
- Hand-made glove setting, Commercialized single-incision multiport setting
- Where
- Taiwan
- Volunteers
- 30 people
- Sponsor
- National Taiwan University Hospital
Acute Appendicitis, Appendicitis Perforated
Bilirubin Levels to Diagnose Appendicitis and Predict Appendiceal Perforation
The goal of this study is to learn if serum bilirubin levels can aid in the diagnosis of acute appendicitis and predict appendiceal perforation
- Trial name
- NCT06956638
- Testing
- Non-interventional
- Where
- Nepal
- Volunteers
- 98 people
- Sponsor
- Nepalese Army Institute of Health Sciences
Appendicitis
Single-incision Laparoscopic (SILS) Versus Conventional Laparoscopic Appendectomy for the Treatment of Acute Appendicitis
Recent advances in laparoscopic instrumentation have made it possible to perform intra-abdominal operations entirely through a small incision that can be hidden within the umbilicus.
- Trial name
- NCT00997516
- Testing
- SILS appendectomy, conventional laparoscopic appendectomy
- Where
- 2 sites in United States
- Volunteers
- 75 people
- Sponsor
- University of California, San Francisco
Appendicitis Acute
Laparoscopically Guided Rectus Sheath Block in Pediatric Appendicitis
The study will investigate the pain control effects of a rectus sheath block after laparoscopic surgery to remove the appendix. A rectus sheath block is the injection of local anesthetic (numbing agent) into the space between the…
- Trial name
- NCT04717193
- Testing
- Rectus Sheath Block with 0.25% bupivicaine with 1:200 000 epinephrine, Local Anesthetic Infiltration with 0.25% bupivicaine with 1:200 000 epinephrine
- Where
- Canada
- Volunteers
- 42 people
- Sponsor
- University of Alberta
Appendicitis, Cholelithiasis
Single Incision Laparoscopy
Laparoscopic surgery being performed with only one small incision via the umbilicus (belly button).
- Conditions
- Appendicitis, Cholelithiasis, Malignant Hypertension
- Trial name
- SIL (NCT00616616)
- Testing
- single incision laparoscopic surgery
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- University of California, San Diego
Appendicitis
Role of Delay and Antibiotics on Perforation Rate While Waiting Appendectomy
This study evaluates the effects of preoperative delay and antibiotics on perforation rate of appendix while waiting surgery for acute appendicitis.
- Trial name
- PERFECT (NCT04378868)
- Testing
- Antibiotics, cefuroxime and metronidazole, No antibiotics, urgent schedule
- Where
- 2 sites in Finland
- Volunteers
- 1,800 people
- Sponsor
- Helsinki University Central Hospital
Appendicitis, Pain
Trial on Postoperative Outcomes According to the Number of Trocar During Laparoscopic Appendectomy
Appendicitis is the most common benign inflammatory disease that requires an operation. Laparoscopic appendectomy using three trocar is generally performed, and reveals good surgical outcomes incluing less pain, early recovey…
- Conditions
- Appendicitis, Pain, Complications
- Trial name
- NCT00816933
- Testing
- appendectomy
- Where
- South Korea
- Volunteers
- 140 people
- Sponsor
- The Catholic University of Korea
Appendicitis Acute, Disbiosis
Differences In Microbiota Profiles Of Pediatric Appendicitis Cases
The microbial profile varies between simple appendicitis (SA) and complicated appendicitis (CA) cases. An appendectomy has been noted to temporarily diminish gut bacterial diversity.
- Conditions
- Appendicitis Acute, Disbiosis, Complicated Appendicitis, Simple Appandiscitis
- Trial name
- NCT07860307
- Testing
- Appendectomy
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Istanbul University
Appendicitis
Peri-operative Analgesia for Single-incision Laparoscopic Appendectomy
Laparoscopic appendectomy is a very common intervention in pediatric surgery. To improve outcomes, some teams have developed the use of single-site laparoscopic appendectomy (SILAP).
- Trial name
- PAMAL (NCT05773521)
- Testing
- SILAP (single incision laparoscopic appendectomy)
- Where
- France
- Volunteers
- 140 people
- Sponsor
- University Hospital, Angers
Acute Appendicitis
Medical Treatment for Acute Appendicitis
Medical treatment for acute appendicitis
- Trial name
- NCT04594486
- Testing
- Medical treatment of acute appendicitis
- Where
- Turkey (Türkiye)
- Volunteers
- 209 people
- Sponsor
- Uşak University
Appendicitis
Wound Healing After Emergency Appendicectomy
The purpose of this trial is to compare two techniques of wound closure in open appendicectomies in adult patients: continuous, absorbable, intradermal suture and interrupted, non-absorbable sutures.
- Trial name
- NCT00913445
- Testing
- appendicectomy
- Where
- Finland
- Volunteers
- 200 people
- Sponsor
- Tampere University Hospital
Appendicitis
Comparison of Medical and Surgical Treatment of Uncomplicated Acute Appendicitis in Children
Several prior studies have demonstrated that medical management of acute appendicitis in adults is a safe first-line therapy option.
- Trial name
- NCT02991937
- Testing
- Piperacillin/Tazobactam, Surgical Treatment
- Where
- United States
- Volunteers
- 39 people, healthy volunteers welcome
- Sponsor
- NYU Langone Health
Incarcerated Hernia, Appendicitis Acute
Prevention of Postoperative Hernias in Emergency Surgery
The aim of this observational study is to understand the risk factors and incidence of postoperative hernias among patients undergoing emergency surgery.
- Conditions
- Incarcerated Hernia, Appendicitis Acute, Cholecystitis, Acute, Ileus
- Trial name
- PROPHECY (NCT06815822)
- Where
- Poland
- Volunteers
- 500 people
- Sponsor
- Jan Kochanowski University
Appendicitis Acute
Online Field Test of an Appendicitis Decision Support Tool
After the recent publication of the CODA Trial comparing antibiotics and surgery for acute appendicitis, the investigators developed a comprehensive decision support tool.
- Trial name
- NCT05219786
- Testing
- Appendicitis Decision Support Tool, Control Infographic
- Where
- United States
- Volunteers
- 194 people, healthy volunteers welcome
- Sponsor
- University of Washington
Appendix Abscess, Appendicitis
The Prevalence of Appendiceal Tumours in Periappendicular Abscess
Complicated and uncomplicated appendicitis follow different epidemiological trends also suggesting different pathophysiology behind these two different forms of appendicitis.
- Conditions
- Appendix Abscess, Appendicitis, Appendix Mass, Appendix Cancer
- Trial name
- PeriAPPAC-T (NCT04634448)
- Testing
- Interval appendectomy, Follow-up MRI at 1 year
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Turku University Hospital