Clinical trials: Appendicitis (Diagnosis)
Appendicitis Acute
Role of Duplex Doppler in Accurate Diagnosis of Appendicitis
To evaluate the role of duplex doppler in diagnosis of appendicitis compared to CT
- Trial name
- NCT04130074
- Testing
- duplex doppler ultra sound and CT
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- abdelRahman Ahmad abdAllah
Appendicitis
Non Absorbable Clips vs Endoloops in Laproscopic Appendicectomy
a) Compare between Nonabsorbable Polymeric Clips and Endoloop ligatures regarding: 1. technical difficulties. 2. operation time. 3. cost effectiveness. 4. postoperative complications. 5. inpatient stay.
- Trial name
- NCT04094480
- Testing
- polymeric non absorbable clips, endoloops
- Volunteers
- 40 people
- Sponsor
- Assiut University
Kawasaki Disease, Appendicitis
Acute Abdomen in Kawasaki Disease
Clinical and histopathological description of three cases of Kawasaki disease with acute abdomen.
- Trial name
- NCT03902262
- Testing
- appendicectomy
- Volunteers
- 3 people
- Sponsor
- National Institute of Pediatrics, Mexico
Complicated Appendicitis, Perforated Appendicitis
Antibiotic Duration in Post-appendectomy Abscess
This is a randomized study of patients 2-17 years old who are diagnosed with perforated appendicitis and develop an abscess after laparoscopy that is subsequently drained.
- Trial name
- NCT03795194
- Testing
- ampicillin/clavulanate
- Where
- United States
- Volunteers
- 7 people
- Sponsor
- Phoenix Children's Hospital
Appendicitis Perforated, Appendectomy, Laparoscopic
Piperacillin/Tazobactam Versus Ceftriaxone and Metronidazole for Children With Perforated Appendicitis
The ALPACA-MC trial is a blinded, multicentre randomized controlled trial comparing two postoperative antibiotic treatments for children undergoing laparoscopic appendectomy for perforated appendicitis.
- Conditions
- Appendicitis Perforated, Appendectomy, Laparoscopic, Antibiotic, Pediatric
- Trial name
- ALPACA-MC (NCT07869095)
- Testing
- Piperacillin/Tazobactam, Ceftriaxone + Metronidazole
- Volunteers
- 180 people
- Sponsor
- McMaster Children's Hospital
Acute Appendicitis, Abdominal Pain
Diagnostic Performance of Serum Calprotectin in Acute Appendicitis
This prospective observational study evaluated the diagnostic performance of serum calprotectin in patients presenting with acute abdominal pain and suspected acute appendicitis.
- Trial name
- SCP-AA (NCT07643142)
- Testing
- Serum Calprotectin Measurement
- Where
- Turkey (Türkiye)
- Volunteers
- 74 people
- Sponsor
- Fatih Sultan Mehmet Training and Research Hospital
Valid MeSH Conditions
Textbook Outcomes in Urgent Appendectomy
A "textbook outcome" patient is defined as one whose surgical course is uneventful, with no complications, readmissions, or mortality.
- Trial name
- APPX_TEXTBOOK (NCT06765044)
- Volunteers
- 500 people
- Sponsor
- Hospital del Mar
Acute Appendicitis
Prospective Comparison of Pro-Adrenomedullin, C-Reactive Protein, and Neutrophil-to-Lymphocyte Ratio for Diagnosing Acute Appendicitis
The goal of this prospective observational study is to evaluate the diagnostic accuracy of pro-adrenomedullin (Pro-ADM) in adults with acute appendicitis and compare its performance with conventional inflammatory biomarkers…
- Trial name
- PROADM-APP (NCT07889544)
- Testing
- Serum Pro-Adrenomedullin Measurement
- Where
- Turkey (Türkiye)
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Bursa Yuksek Ihtisas Training and Research Hospital
Acute Appendicitis, Superficial SSI
Laparoscopic vs Open Appendectomy
his randomized controlled trial was conducted to compare the frequency of superficial surgical site infections (SSIs) following laparoscopic appendectomy and open appendectomy in patients undergoing surgical treatment for acute…
- Trial name
- NCT07841444
- Testing
- Laparoscopic appendectomy, Open Appendectomy
- Where
- Pakistan
- Volunteers
- 276 people
- Sponsor
- Quaid-e-Azam Medical College
ERAS, Pediatric Disorder
Studding the Implementation of ERAS Protocols in Pediatric Surgery
this is a retrospective cohort, descriptive study, investigating the role of ERAS protocols, in pediatric surgery and evaluate the feasibility and effectiveness of implementing these protocols
- Conditions
- ERAS, Pediatric Disorder, Appendicitis, Hydrocele
- Trial name
- NCT04870242
- Testing
- Observational study, non-interventional
- Where
- Jordan
- Volunteers
- 178 people
- Sponsor
- University of Jordan
Appendicitis
Diagnosis of Acute Appendicitis: Low-dose Computed Tomography (CT) Versus Standard-dose CT
The purpose of this study is to determine whether low-dose CT is not inferior to standard-dose CT in the rate of unnecessary appendectomy.
- Trial name
- NCT00913380
- Testing
- Diagnostic CT
- Where
- South Korea
- Volunteers
- 891 people
- Sponsor
- Seoul National University Bundang Hospital
Appendicitis Surgery
Complex And Simple Appendicitis: REstrictive or Liberal Post-operative Antibiotic eXposure (CASA RELAX) - Atrium Health
To demonstrate the safety, efficacy, and feasibility of short-course post-operative antibiotic treatment for simple and complicated appendicitis
- Trial name
- NCT05746520
- Testing
- Antibiotic
- Where
- United States
- Volunteers
- 268 people
- Sponsor
- Wake Forest University Health Sciences
Appendicitis
Pediatric Appendicitis Pathway Study
The purpose of this study is to test a standardized approach for children being evaluated for appendicitis in the emergency department.
- Trial name
- NCT01192620
- Where
- United States
- Volunteers
- 178 people
- Sponsor
- Oregon Health and Science University
Appendicitis
A Randomized Controlled Trial on Wound Irrigation in Open Appendectomy.
A large retrospective study compared wound irrigation with antiseptic solution, with antimicrobial agent, and with normal saline in patients undergoing open appendectomy and concluded an evident superiority of antibiotic wound…
- Trial name
- NCT04332809
- Testing
- saline-gentamicin irrigation, saline irrigation
- Where
- Egypt
- Volunteers
- 208 people
- Sponsor
- Mansoura University
Appendicitis
Practical Advantages of Single-port Over Three-port Laparoscopic Appendectomy in Children
Despite growing popularity, practical advantages of single-port laparoscopic appendectomy (SLA) over conventional three-port laparoscopic appendectomy (CLA) have yet to be established well in pediatric population.
- Trial name
- PASTA (NCT03106467)
- Testing
- Single-port laparoscopic appendectomy, Three-port laparoscopic appendectomy
- Where
- South Korea
- Volunteers
- 400 people
- Sponsor
- Hallym University Medical Center
Acute Appendicitis
The Role of Contrast Enhanced Ultrasound in Appendicitis
This study seeks to determine the efficacy of Contrast Enhanced Ultrasound (CEUS) in improving the diagnosis of acute appendicitis in children, when compared to the standard grey-scale ultrasound.
- Trial name
- NCT03687502
- Testing
- Sulfur hexafluoride lipid-type A microspheres
- Where
- United States
- Volunteers
- 37 people
- Sponsor
- Children's Mercy Hospital Kansas City
Appendicitis
TICAP - Titanium Clips for Appendiceal Stump Closure
Laparoscopic appendectomy is progressively accepted as the treatment of choice for acute appendicitis. Although the surgical technique of laparoscopic appendectomy has been well established, some controversy exists regarding the…
- Trial name
- TICAP (NCT01734837)
- Testing
- DS-Ligature Clip
- Where
- 9 sites in United States, Germany
- Volunteers
- 390 people
- Sponsor
- Aesculap AG
Acute Appendicitis
Radiomic Modeling in Differentiating Uncomplicated From Complicated Acute Appendicitis
Non-operative management (NOM) with antibiotics may be a safe alternative to surgery for uncomplicated appendicitis, but preoperative differentiation between uncomplicated and complicated appendicitis is challenging.
- Trial name
- NCT05843630
- Testing
- without
- Where
- China
- Volunteers
- 250 people
- Sponsor
- Kecheng Zhang
Appendicitis, Acute, Appendectomy
Video-Based Grading of Intraoperative Adverse Events in Pediatric Laparoscopic Appendectomy
Acute appendicitis is the most common surgical emergency in children, and laparoscopic appendectomy is its standard treatment. Although intraoperative adverse events (iAEs) are recognized as an important determinant of surgical…
- Conditions
- Appendicitis, Acute, Appendectomy, Intraoperative Complications, Patient Safety
- Trial name
- PedAppy-iAE (NCT07794618)
- Testing
- Laparoscopic appendectomy
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people
- Sponsor
- Ahmet Burak Doğan, MD
Acute Appendicitis, Appendectomy
RICA (ERAS) Pathway Adherence and Early Discharge Feasibility After Urgent Uncomplicated Appendectomy (APENERAS)
This multicenter, prospective observational study (APENERAS) evaluates adherence to the RICA (ERAS Zaragoza 2022) perioperative care pathway in adults undergoing urgent laparoscopic appendectomy for uncomplicated acute…
- Conditions
- Acute Appendicitis, Appendectomy, Ambulatory Surgery
- Trial name
- APENERAS (NCT07401407)
- Where
- 4 sites in Spain
- Volunteers
- 193 people
- Sponsor
- Hospital Galdakao-Usansolo