Clinical trials: Appendicitis Acute
Acute Appendicitis, Abdominal Pain
Diagnostic Performance of Serum Calprotectin in Acute Appendicitis
This prospective observational study evaluated the diagnostic performance of serum calprotectin in patients presenting with acute abdominal pain and suspected acute appendicitis.
- Trial name
- SCP-AA (NCT07643142)
- Testing
- Serum Calprotectin Measurement
- Where
- Turkey (Türkiye)
- Volunteers
- 74 people
- Sponsor
- Fatih Sultan Mehmet Training and Research Hospital
Abdominal Pain, Acute Pain
Diagnostic Performance of Low-Dose CT for Acute Abdominal Conditions
The goal of this non-inferiority observational study is to assess the diagnostic performance of low-dose CT with deep learning image reconstruction (DLIR) in adult participants with acute abdominal conditions.
- Conditions
- Abdominal Pain, Acute Pain, Acute Cholecystitis, Acute Appendicitis
- Trial name
- DETECT_Acute (NCT05651360)
- Testing
- low-dose CT
- Where
- 2 sites in Denmark, Norway
- Volunteers
- 246 people
- Sponsor
- Oslo University Hospital
Acute Appendicitis
Efficacy of Transversus Abdominis Plane Block in Alleviating Acute Appendicitis
This study aims to evaluate the efficacy of Transversus Abdominis Plane (TAP) block in preoperative pain management for patients diagnosed with acute appendicitis who are scheduled for emergency surgery in the emergency…
- Trial name
- NCT06808737
- Testing
- Transversus Abdominis Plane Blockage
- Where
- Turkey (Türkiye)
- Volunteers
- 105 people
- Sponsor
- Ankara City Hospital Bilkent
Acute Uncomplicated Appendicitis
Efficacy of Non Operative Treatment With Amoxicillin/Clavulanic Acid Versus Surgical Treatment in Acute Uncomplicated Appendicitis in Children
The majority of children with uncomplicated acute appendicitis may be considered for either a non-operative or an operative management.
- Trial name
- NACAC (NCT07587450)
- Testing
- Amoxi Clavulanate, appendicectomy
- Where
- 10 sites in France
- Volunteers
- 724 people
- Sponsor
- University Hospital, Toulouse
Appendectomy, Appendicitis
Early Detection of Infection Using the Fitbit in Pediatric Surgical Patients
The purpose of this study is to analyze Fitbit data to predict infection after surgery for complicated appendicitis and the effect this prediction has on clinician decision making.
- Conditions
- Appendectomy, Appendicitis, Appendicitis Acute
- Trial name
- i-DETECT (NCT06395636)
- Testing
- Infection-Prediction Algorithm
- Where
- 4 sites in United States
- Volunteers
- 500 people
- Sponsor
- Ann & Robert H Lurie Children's Hospital of Chicago
Intra Abdominal Infections, Appendicitis Acute
Diagnosis of Abdominal Pain Using RNA Levels: The NATURAL Study
The NATURAL Study is a prospective, observational, pragmatic study of RNA biomarkers of infections to aid in the diagnosis of abdominal pain.
- Conditions
- Intra Abdominal Infections, Appendicitis Acute, Pyelonephritis, Diverticulitis
- Trial name
- NATURAL (NCT07579312)
- Testing
- TruNAV, an RNA-based blood test for host immune activation by infections
- Where
- United States
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- True Bearing Diagnostics, Inc.
Post Operative Antibiotic Therapy of Acute Appendicitis
One Versus Five Days of Antibiotics After Appendectomy
The goal of this clinical trial is to learn if a one-day course of antibiotics after appendectomy surgery works as well as a five-day course to prevent infections in children and adults (aged 10 years and older) with…
- Trial name
- SSI-IAA (NCT07563933)
- Testing
- a single day (24 hours) post operative
- Where
- Egypt
- Volunteers
- 200 people
- Sponsor
- Ministry of Health and Population, Egypt
Appendicitis Acute, Gangrenous Appendicitis
Out-patiente Management for Gangrenous Acute Appendicitis: The PENDI-CSI II Randomized Clinical Trial.
PHASE II-III CLINICAL TRIAL TO EVALUATE THE SAFETY, EFFECTIVENESS AND EFFICIENCY OF DISCHARGE TO OUTPATIENT SURGERY IN PATIENTS WITH ACUTE GANGRENOUS APPENDICITIS UNDERGOING EMERGENCY SURGERY.
- Trial name
- PENDI-CSI II (NCT07521969)
- Testing
- outpatient surgery, Hospitalization
- Where
- Spain
- Volunteers
- 122 people
- Sponsor
- Fundación Pública Andaluza para la gestión de la Investigación en Sevilla
Acute Appendicitis
Comparison of Diagnostic Methods in Patients Operated for Suspected Appendicitis
Acute appendicitis is one of the most common surgical emergencies, but diagnostic uncertainty may still lead to unnecessary appendectomy in some patients.
- Trial name
- APP-AIR (NCT07496723)
- Where
- Turkey (Türkiye)
- Volunteers
- 200 people
- Sponsor
- Sanliurfa Education and Research Hospital
Pregnancy Complications, Acute Appendicitis
Fetal Outcomes Among Pregnant Emergency General Surgery Patients
Approximately 1 in 500 pregnant women require non-obstetric surgery. Surgical care for the pregnant woman raises concern for complications adversely affecting pregnancy outcomes.
- Conditions
- Pregnancy Complications, Acute Appendicitis, Acute Cholecystitis, Biliary Pancreatitis
- Trial name
- NCT05085353
- Testing
- non-obstetric acute general surgical disease
- Where
- United States
- Volunteers
- 3 people
- Sponsor
- Methodist Health System
Acute Appendicitis
Antibiotics vs Surgery in Acute Appendicitis
The aim of this study is to identify clinical, laboratory, and imaging parameters that can predict the most appropriate treatment strategy in patients diagnosed with acute appendicitis.
- Trial name
- NCT07492329
- Testing
- surgery (any volume) and / or pharmaceuticals treatment initiated or planned or only dynamic observation, in accordance with current clinical guidelines, Antibiotic
- Where
- Turkey (Türkiye)
- Volunteers
- 400 people
- Sponsor
- Sebahattin Celik MD
Acute Appendicitis
TACTILE : Validation of a Teleconsultation-Based Predictive Score for the Diagnosis of Acute Appendicitis in Children Using Artificial Intelligence Methods
Acute appendicitis is the most common abdominal surgical emergency in children and a frequent cause of pediatric emergency department visits.
- Trial name
- TACTILE (NCT07479849)
- Testing
- Score-based appendicitis risk classification in teleconsultation
- Where
- France
- Volunteers
- 1,500 people
- Sponsor
- University Hospital, Angers
Appendicitis, Appendicitis Acute
Clinical Study of PEG Bowel Preparation in Appendectomy Patients
Colonoscopy is a necessary item of physical examination for colorectal cancer. For high-risk groups, annual physical examination is the most effective way of early prevention; At present, a large amount of polyethylene glycol…
- Trial name
- NCT07478029
- Testing
- Bowel Preparation with Polyethylene Glycol (PEG) Laxatives
- Where
- China
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Huaping Xie
Appendicitis Acute
First Appendectomy Using Revolve Surgical Robotic Arm
This study is testing a new surgical device called the Revolve Surgical System (RSS) during appendix removal surgery. The RSS is designed to help surgeons perform minimally invasive surgery with improved precision and stability…
- Trial name
- NCT07455487
- Testing
- Revolve Surgical System - RSS
- Volunteers
- 3 people
- Sponsor
- Unity Health Toronto
Acute Appendicitis
Management of Acute Appendicitis Pain in the Emergency Department
This study aims to compare the effectiveness of TAP (Transversus Abdominal Plane) block, ESPB (Erector Spinal Plane Block), and tramadol in preoperative pain management for patients diagnosed with acute appendicitis and…
- Trial name
- NCT06808087
- Testing
- Transversus abdominis plane blockage, Erector spinae plane blockage, Tramadol
- Where
- Turkey (Türkiye)
- Volunteers
- 96 people
- Sponsor
- Ankara City Hospital Bilkent
Acute Appendicitis, Appendectomy
RICA (ERAS) Pathway Adherence and Early Discharge Feasibility After Urgent Uncomplicated Appendectomy (APENERAS)
This multicenter, prospective observational study (APENERAS) evaluates adherence to the RICA (ERAS Zaragoza 2022) perioperative care pathway in adults undergoing urgent laparoscopic appendectomy for uncomplicated acute…
- Conditions
- Acute Appendicitis, Appendectomy, Ambulatory Surgery
- Trial name
- APENERAS (NCT07401407)
- Where
- 4 sites in Spain
- Volunteers
- 193 people
- Sponsor
- Hospital Galdakao-Usansolo
Appendicitis (Diagnosis), Acute Appendicitis
Alvarado Score in the Meta Department
The project aims to determine the frequency of use of the Alvarado score among emergency department physicians at facilities in Villavicencio, Colombia.
- Trial name
- NCT07370896
- Where
- Colombia
- Volunteers
- 125 people, healthy volunteers welcome
- Sponsor
- Hospital Departamental de Villavicencio
Intra-Abdominal Infections, Intestinal Obstruction
Capillary Leak Index as a Prognostic Indicator for Post-Operative Abdominal Sepsis in Critically Ill Patients
In this study the investigators going to evaluate the "CLI" as an early prognostic indicator for post-operative abdominal sepsis in critically ill patients.
- Conditions
- Intra-Abdominal Infections, Intestinal Obstruction, Appendicitis Acute, Perforated Viscus
- Trial name
- CLI (NCT06901544)
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Ain Shams University
Acute Appendicitis, Acute Appendicitis With Rupture
Prioritisation of Acute Appendicitis Using Appendistat Score
Introduction Although non-operative management of acute appendicitis may be appropriate in selected cases, surgery remains the gold standard treatment.
- Trial name
- APEX (NCT07197489)
- Where
- 2 sites in United Kingdom
- Volunteers
- 592 people
- Sponsor
- University College, London
Acute Appendicitis
Feasibility of Outpatient Appendectomy for Acute Appendicitis
The aim of our monocentric prospective in intention-to-treat study is to evaluate the feasibility of outpatient appendectomy for non complicated acute appendicitis.
- Trial name
- APPENDAMBU (NCT01839435)
- Testing
- outpatient surgery
- Where
- France
- Volunteers
- 120 people
- Sponsor
- Centre Hospitalier Universitaire, Amiens