Clinical trials: Appendicitis Acute
Acute Appendicitis
Initial Antibiotics and Delayed Appendectomy for Acute Appendicitis
Several recent studies have examined the feasibility and benefits of nonoperative treatment of perforated appendicitis in children.
- Trial name
- NCT01697059
- Testing
- Piperacillin + Amoxicillin
- Where
- United States
- Volunteers
- 73 people
- Sponsor
- Rhode Island Hospital
Complicated Appendicitis
Causes of Complicated Appendicitis at Referral Hospital
The study was conducted on a medical record of previously treated patients for acute appendicitis at HFSUH, Harar, Ethiopia. The study design was case-control with a total sample size of 402.
- Trial name
- AA (NCT05005104)
- Where
- Ethiopia
- Volunteers
- 402 people
- Sponsor
- Haramaya Unversity
Acute Appendicitis
Diagnostic Importance of the C-reactive Protein From Blood and Saliva in Children With Acute Appendicitis
Diagnosing acute appendicitis in children is still a challenge even for experienced clinicians. Failure to recognize this acute condition can result in perforation, with consequent peritonitis, or misdiagnosis can result in…
- Trial name
- NCT06051825
- Testing
- Blood specimen collection for C-reactive protein (CRP) and WBC (white blood cells). Saliva specimen collection for analysis of CRP levels
- Volunteers
- 100 people
- Sponsor
- University Hospital of Split
Appendectomy, Laparoscopic, Acute Appendicitis
Feasibility and Safety of a Pediatric ERAS Protocol for Laparoscopic Appendectomy
Acute appendicitis is the most common surgical emergency in children. Despite the widespread adoption of laparoscopic appendectomy, postoperative care still varies widely between institutions, with prolonged fasting, opioid-based…
- Conditions
- Appendectomy, Laparoscopic, Acute Appendicitis, Pediatric Surgery, ERAS
- Trial name
- NCT07643285
- Testing
- Comprehensive 20-Item Pediatric ERAS Protocol
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people
- Sponsor
- Ahmet Burak Doğan, MD
Appendicitis Acute, Safety Issues
Review of Efficacy of Used ultraSonic Energy Device
Single-use medical instruments are intended by the manufacturers for single-use only or for single-patient-use only. Nevertheless, single-use instruments are being reused more than once in many countries around the world.
- Conditions
- Appendicitis Acute, Safety Issues, Complication of Surgical Procedure, Device Induced Injury
- Trial name
- REUSED (NCT04226482)
- Testing
- New Device, Used Device
- Where
- 2 sites in Croatia
- Volunteers
- 100 people
- Sponsor
- University of Split, School of Medicine
Appendicitis
Antibiotic Therapy Versus Appendectomy for Acute Appendicitis
The purpose of the study is to demonstrate that antibiotic therapy is as safe and effective as appendectomy for the treatment of acute non complicated appendicitis.
- Trial name
- NCT00135603
- Testing
- amoxicillin/clavulanate potassium, appendectomy
- Where
- 5 sites in France
- Volunteers
- 243 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Appendicitis
Morphine Analgesia in Patients With Acute Appendicitis
The purpose of the study is to evaluate morphine effect on pain reduction and diagnostic accuracy in patients admitted to emergency ward with the diagnosis of acute appendicitis.
- Trial name
- NCT00477061
- Testing
- Morphine
- Where
- Iran
- Volunteers
- 71 people
- Sponsor
- Tehran University of Medical Sciences
Laparoscopic Appendectomy, Complicated Appendicitis
Fast Track Therapeutic Model in Acute Complicated Appendicitis in Pediatrics
To evaluate whether a postoperative therapeutic strategy, Fast Track, aimed at shortening hospital stay in pediatric patients undergoing laparoscopic appendectomy for complicated acute appendicitis, yields outcomes that are not…
- Conditions
- Laparoscopic Appendectomy, Complicated Appendicitis, Periappendicular Abscess
- Trial name
- FTAA (NCT05761080)
- Testing
- Oral amoxicillin-clavulanic acid (40mg/kg in 3 times/day; maximum dose 3g/day), Inpatient postpoperative intravenous antibiotic treatment according to the established protocol in each center
- Where
- 12 sites in Spain
- Volunteers
- 772 people
- Sponsor
- Fundació Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau
Acute Appendicitis
Laparoscopic Versus Open Appendectomy
Comparison of open and laparoscopic appendectomy
- Trial name
- NCT01967745
- Testing
- laparoscopic appendectomy, open appendectomy
- Where
- Croatia
- Volunteers
- 100 people
- Sponsor
- Varazdin General Hospital
Appendicitis Acute
Low-dose Contrast Media for Low-kVp Abdomen CT
The purpose of this clinical study is to test the performance of low radiation dose abdominal CT combined with low dose contrast media for the diagnosis of acute appendicitis in young patients.
- Trial name
- NCT05878665
- Testing
- Weight-adjusted low-dose contrast media paired with low-radiation dose abdomen CT
- Where
- South Korea
- Volunteers
- 109 people
- Sponsor
- Bohyun Kim
Appendicitis Acute
First Appendectomy Using Revolve Surgical Robotic Arm
This study is testing a new surgical device called the Revolve Surgical System (RSS) during appendix removal surgery. The RSS is designed to help surgeons perform minimally invasive surgery with improved precision and stability…
- Trial name
- NCT07455487
- Testing
- Revolve Surgical System - RSS
- Volunteers
- 3 people
- Sponsor
- Unity Health Toronto
Appendicitis
Appendectomy Versus Non-Operative Treatment For Acute Non-Perforated Appendicitis in Children
Rationale and Aim: The standard treatment for acute appendicitis in children is appendectomy. An increasing body of evidence from the adult literature suggests that acute appendicitis may be treated effectively with antibiotics…
- Trial name
- APPY (NCT02687464)
- Testing
- Non-operative treatment, Appendectomy
- Where
- United States
- Volunteers
- 978 people
- Sponsor
- Children's Mercy Hospital Kansas City
Acute Appendicitis
Peritoneal Closure Versus Non Closure During Open Appendectomy
There has been no consensus over closure versus non closure of peritoneum during abdominal operations. The aim of this study is to compare the effect of peritoneal closure versus non closure over postoperative pain, early…
- Trial name
- NCT02803463
- Testing
- open appendectomy with peritoneal closure, open appendectomy without peritoneal closure
- Where
- Turkey (Türkiye)
- Volunteers
- 112 people
- Sponsor
- Bezmialem Vakif University
Acute Complicated Appendicitis With Abscess
Appendicoliths in Acute Complicated Appendicitis Patients With Abscess
Complicated appendicitis, characterized by the presence of an abscess or perforation, involves acute inflammation of the peritoneum secondary to an infection of the appendix, presenting additional challenges for management.
- Trial name
- NCT06469086
- Testing
- Clinical data collection
- Volunteers
- 100 people
- Sponsor
- Shanghai Zhongshan Hospital
Appendicitis With Peritonitis
Benefit of Hypnosis on Smartphone for Acute Post-operative Pain (HYPNO-APP)
Appendicitis is a common pathology and the one of the most common surgical procedures performed in France. Young subjects are the most frequent patients with appendicitis.
- Trial name
- NCT05854914
- Testing
- Use of hypnosis videos
- Where
- France
- Volunteers
- 20 people
- Sponsor
- Centre Hospitalier Universitaire de Nice
To Report the Rare Occurrence of Meckel's Diverticulum
The Uncommon Complications of Meckel's Diverticulum
Acas series study was conducted on emergency acute abdomen patients who finally confirmed intraoperatively as Meckel's diverticulum with different complications.
- Trial name
- MD (NCT05793385)
- Testing
- operative intervention
- Where
- Ethiopia
- Volunteers
- 4 people
- Sponsor
- Haramaya Unversity
Abdominal Pain, Testicle Pain
Diagnosis of Acute Appendicitis, Ovary Torsion and Inflammation, and Testicular Torsion and Inflammation by Infrared Thermography
Thermal, or infrared, energy is the part of electromagnetic radiation that an observer perceives as heat. Infrared thermography allows us to visualize temperature distribution of the human body and has been used in medical…
- Trial name
- NCT01079650
- Where
- Israel
- Volunteers
- 50 people
- Sponsor
- Assaf-Harofeh Medical Center
Perforated Appendicitis
Diagnostic Value of Hyperbilirubinaemia as a Predictive Factor for Appendiceal Perforation in Acute Appendicitis
The values of laboratory examinations which are useful for the diagnoses of appendicitis are white blood cell count (WBC), C-reactive protein (CRP) and erythrocyte blood sedimentation rate (ESR).
- Trial name
- NCT00677417
- Volunteers
- 538 people
- Sponsor
- Ruhr University of Bochum
Appendectomy, Laparoscopic, Appendicitis Acute
Effect Of Specimen Extraction Site And Local Anesthesia On Postoperative Pain In Laparoscopic Appendectomy
The aim of this prospective, randomized study is to evaluate the effects of two different specimen extraction sites (periumbilical versus left lower quadrant) and the routine application of port-site local anesthesia infiltration…
- Conditions
- Appendectomy, Laparoscopic, Appendicitis Acute, Pain Management
- Trial name
- NCT07824908
- Testing
- Port-site local anesthesia infiltration
- Where
- Turkey (Türkiye)
- Volunteers
- 300 people
- Sponsor
- YUNUS YÜKSEL
Appendicitis Acute, Appendectomy
Evaluating the Safety and Efficacy of a Outpatient Appendectomy
This study evaluates the Safety and Efficacy of a outpatient appendectomy. Half of participants will be perform the hospitalization, while the other half will undergo the outpatient appendectomy
- Trial name
- PENDI_CSI (NCT04464382)
- Testing
- Outpatient (OA), Hospitalization appendectomy (HA)
- Where
- Spain
- Volunteers
- 291 people
- Sponsor
- Fundación Pública Andaluza para la gestión de la Investigación en Sevilla