Clinical trials: Appetite Loss, open to volunteers
Anorexia Nervosa
Effectiveness Trial of Temperament Based Therapy With Support (TBT-S)
The main aim of this project is to determine the short and long-term effectiveness of an out-patient treatment for patients with anorexia nervosa.
- Trial name
- NCT06497101
- Testing
- Temperament Based Therapy with Support (TBT-S)
- Where
- Norway
- Volunteers
- 120 people
- Sponsor
- Oslo University Hospital
Anorexia Nervosa, Bulimia Nervosa
Development of Gastrointestinal Symptoms in Patients With Anorexia Nervosa and Bulimia Nervosa During Weight Rehabilitation Over Time, Depending on the Nutritional Strategy
This prospective observational study investigates the development of gastrointestinal (GI) symptoms in patients with anorexia nervosa (AN) and bulimia nervosa (BN) during multi-week inpatient weight rehabilitation.
- Trial name
- GastroRehab (NCT07112014)
- Where
- Germany
- Volunteers
- 185 people
- Sponsor
- University Hospital Tuebingen
Eating Disorders, Psychiatric Comorbidities
Structural Brain Volumetry Changes in Eating Disorders.
The goal of this observational study is to investigate the relationship between structural brain changes and psychiatric comorbidities in individuals diagnosed with eating disorders (EDs).
- Trial name
- NCT07131852
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Assiut University
Anorexia Nervosa
Safety, Therapeutic Potential, and Mechanisms of Two Psilocybin Doses, Administered With Psychological Support in Young Adults With Anorexia Nervosa
The goal of this clinical trial is to learn if psilocybin, given with psychological support, is safe and helps treat anorexia nervosa in young adults.
- Trial name
- psiAN (NCT07169747)
- Testing
- Psilocybin
- Where
- Sweden
- Volunteers
- 40 people
- Sponsor
- Region Skane
COPD (Chronic Obstructive Pulmonary Disease), Sarcopenia in Elderly
The Aim of the Study is to Decipher the Alterations in Signalling Pathways of Skeletal Muscle Stem Cells (Satellite Cells (SCs)) in Individuals With COPD, as Well as to Examine the Effect of Exercise Training on SCs.
The aim of the study is to decipher the alterations in signalling pathways of skeletal muscle stem cells (satellite cells (SCs)) in individuals with COPD, as well as to examine the effect of exercise training on SCs.
- Conditions
- COPD (Chronic Obstructive Pulmonary Disease), Sarcopenia in Elderly, Skeletal Muscle Atrophy, Cachexia-Anorexia Syndrome
- Trial name
- SCOOP (NCT07923656)
- Testing
- Exercise training
- Where
- 3 sites in France
- Volunteers
- 26 people
- Sponsor
- University Hospital, Bordeaux
Eating Disorders
Be Body Brave: Digital Written Exposure Therapy for Eating Disorders
Current eating disorder (ED) treatment options are both inaccessible (80% of people with EDs do not access treatment) and not entirely successful (most people with an ED do not reach full remission).
- Trial name
- BBB (NCT07914712)
- Testing
- Imaginal exposure, Eating disorder journaling
- Volunteers
- 900 people
- Sponsor
- University of Louisville
Juvenile Idiopathic Arthritis, Diabetes
Health and Exercise Response in Children With Chronic and Auto-immune Pathologies
The aim of the present project is to assess the effects of the chronic diseases and their associated treatments chronic paediatric diseases (CPD), to further understand their impact on physical fitness for public health…
- Conditions
- Juvenile Idiopathic Arthritis, Diabetes, Inflammatory Bowel Disease, Cancer Survivor
- Trial name
- HERCCULE (NCT03913962)
- Testing
- indirect calorimetry
- Where
- France
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- University Hospital, Clermont-Ferrand
Anorexia in Adolescence, Anorexia Nervosa
3-Dimensional Optical Scanning to Assess and Monitor Malnutrition in Eating Disorders (3D-ED) Study
People with anorexia nervosa often become medically unstable because of severe malnutrition and require hospitalization for nutritional rehabilitation.
- Conditions
- Anorexia in Adolescence, Anorexia Nervosa, Anorexia Nervosa, Atypical, Anorexia Nervosa, Binge Eating/Purging Type
- Trial name
- 3D-ED (NCT07726524)
- Where
- 2 sites in United States
- Volunteers
- 90 people
- Sponsor
- University of California, San Francisco
Anorexia Nervosa, Caregiver Burden
Online FBT-DBT Caregiver Intervention for Caregivers of Individuals With Anorexia Nervosa
Anorexia nervosa (AN) is a severe psychiatric disorder characterized by a chronic and relapsing course. Caregivers of individuals with AN often experience substantial caregiving burden, emotional distress, and impairment in…
- Trial name
- NCT07734779
- Testing
- Online FBT-DBT Intervention, Online Supportive Psychological Intervention
- Where
- China
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Shanghai Mental Health Center
Eating Disorders in Adolescence, Anorexia Nervosa
Evaluation of a New Treatment Program for Adolescents With Eating Disorders: MINERVA Program
The aim of this study is to investigate the efficacy, efficiency, and patient experience of a new intervention program on adolescents with high-complexity eating disorders (ED).
- Conditions
- Eating Disorders in Adolescence, Anorexia Nervosa, Bulimia Nervosa, Binge-Eating Disorder
- Trial name
- NCT06431854
- Testing
- ED-MINERVA Program
- Where
- Spain
- Volunteers
- 120 people
- Sponsor
- Fundació Sant Joan de Déu
Anorexia Nervosa, Bulimia Nervosa
Eating Disorders Genetics Initiative 2
The overarching intention of the Eating Disorder Genetics Initiative 2 (EDGI2) is to increase sample size, diversity, and eating disorder phenotypes.
- Conditions
- Anorexia Nervosa, Bulimia Nervosa, Binge-Eating Disorder, Avoidant Restrictive Food Intake Disorder
- Trial name
- EDGI2 (NCT06594913)
- Testing
- Eating disorder diagnosis group
- Where
- 5 sites in United States, Australia and 3 more
- Volunteers
- 20,000 people, healthy volunteers welcome
- Sponsor
- University of North Carolina, Chapel Hill
Eating Disorders, Anorexia Nervosa
Exploratory Study of Sensory Profile and Coping Strategies in Eating Disorders
This descriptive study aims primarily to characterize the sensory profile of patients with eating disorders (divided into three diagnostic groups: anorexia nervosa, boulimia nervosa and hyperphagia), controlling for possible…
- Conditions
- Eating Disorders, Anorexia Nervosa, Boulimia Nervosa, Hyperphagia
- Trial name
- SensoryCop (NCT07031037)
- Testing
- Scales
- Where
- France
- Volunteers
- 150 people
- Sponsor
- Centre Hospitalier Esquirol
Advanced Malignant Solid Neoplasm, Advanced Biliary Tract Carcinoma
Olanzapine for the Management of Cancer Associated Appetite Loss in Patients With Advanced Esophagogastric, Hepatopancreaticobiliary, Colorectal or Lung Cancer
This phase II trial tests how well olanzapine works in managing cancer cachexia in patients experiencing esophagogastric, hepatopancreaticobiliary, colorectal, or lung cancer that may have spread from where it first started to…
- Conditions
- Advanced Malignant Solid Neoplasm, Advanced Biliary Tract Carcinoma, Advanced Esophageal Carcinoma, Metastatic Esophageal Carcinoma
- Trial name
- NCT05705492
- Testing
- Olanzapine, Questionnaire Administration
- Where
- United States
- Volunteers
- 66 people
- Sponsor
- OHSU Knight Cancer Institute
Anorexia Nervosa
Confirming the Effectiveness of Online Guided Self-Help Family-Based Treatment for Adolescent Anorexia Nervosa
With an incidence rate of about 1%, Anorexia Nervosa (AN) is a serious mental disorder associated with high mortality, morbidity, and cost.
- Trial name
- NCT05563649
- Testing
- Online Guided Self-Help-Family-based Treatment, FBT via Videoconferencing
- Where
- 2 sites in United States, Canada
- Volunteers
- 200 people
- Sponsor
- Stanford University
Frailty, Malnutrition
Impact of Auditory Stimulation in Eating Pleasure (EDERE 2021)
Background. Decreased taste and smell contribute to loss of appetite (anorexia), and the resulting protein-energy malnutrition increases the frailty of the elderly.
- Conditions
- Frailty, Malnutrition, Anorexia, Presbycusis
- Trial name
- EDERE 2021 (NCT04923087)
- Testing
- Compare the noise and pleasure of crunching between two hyperprotein nutritional supplements
- Where
- France
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire de Nice
Anorexia Nervosa, Body Image Disturbance
Interoceptive Mechanisms of Body Image Disturbance in Anorexia Nervosa
The proposed study utilizes a randomized experimental therapeutics design to test a mechanistic framework linking interoceptive processing and disturbed body image, with the purpose of informing the development of future…
- Conditions
- Anorexia Nervosa, Body Image Disturbance, Interoception
- Trial name
- NCT06332963
- Testing
- Floatation-REST, IFT, EFT
- Where
- United States
- Volunteers
- 102 people
- Sponsor
- Laureate Institute for Brain Research, Inc.
Deep Brain Stimulation
Efficacy and Safety of Combo-stim Deep Brain Stimulation for Treatment-refractory Mental Disorders
This is a multi-center, single arm, prospective, open-label, extendable study for the efficacy and safety of combo-stim deep brain stimulation for treatment-refractory mental disorders (obsessive-compulsive disorder…
- Trial name
- NCT06112067
- Testing
- deep brain stimulation
- Where
- China
- Volunteers
- 18 people
- Sponsor
- Shanghai Mental Health Center
Anorexia Nervosa, Autism Spectrum Disorder
TRANPAS - TReating Anorexia Nervosa Plus Autism Spectrum
In a pilot study, the investigators will validate a so-called autism care location in an inpatient ward. The care location will be adapted for patients with anorexia nervosa (AN) and concurrent autism (AN+autism).
- Trial name
- TRANPAS (NCT06368687)
- Testing
- Anorexia nervosa plus autism
- Volunteers
- 10 people
- Sponsor
- Göteborg University
Nasopharyngeal Cancinoma (NPC)
Prophylactic Nanocrystalline Megestrol Acetate Versus Placebo for Chemoradiotherapy-Related Anorexia in Nasopharyngeal Carcinoma
This phase III randomized, double-blind, placebo-controlled trial evaluates whether nanocrystalline megestrol acetate can reduce anorexia in patients with locally advanced nasopharyngeal carcinoma (NPC) undergoing concurrent…
- Trial name
- NCT07796789
- Testing
- Nanocrystalline Megestrol Acetate Oral Suspension
- Where
- 3 sites in China
- Volunteers
- 204 people
- Sponsor
- Sun Yat-sen University
Anorexia Nervosa
Assessment of the Impact of Early Treatment for Anorexia Nervosa in a Day Hospital on Food Symptomatology, the Outcome of Young Patients, and the Family Experience
During the management of chronic illnesses, the day hospital (DH) serves as a brief and effective alternative to traditional hospitalization, offering access to multidisciplinary care.
- Trial name
- EVA-FAM (NCT06218472)
- Testing
- Day Hospital Treatment, Multidisciplinary follow-up "as usual" within the service, Conduct semi-structured qualitative interviews
- Where
- France
- Volunteers
- 164 people, healthy volunteers welcome
- Sponsor
- Assistance Publique - Hôpitaux de Paris