Clinical trials: Appetite Loss
Anxiety, Anorexia Nervosa
Treatment of Anxiety and Anorexia Nervosa in Adolescents
Adolescents with anorexia nervosa frequently have associated anxiety, and standard medications used for anxiety are unhelpful when patients are malnourished.
- Trial name
- TAANA (NCT01933243)
- Testing
- Fish oil
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- Andrea Bonny
Eating Disorders
Comparing the Effectiveness of Two Therapies to Treat Signs of Anorexia Nervosa in Adolescents
This study will compare the effectiveness of two therapies to treat early signs of anorexia nervosa in adolescents.
- Trial name
- NCT00418977
- Testing
- Family-Based Therapy ("Maudsley Method"), Individual Supportive Psychotherapy
- Where
- United States
- Volunteers
- 59 people
- Sponsor
- Icahn School of Medicine at Mount Sinai
Anorexia Nervosa, Atypical Anorexia Nervosa
Optimizing Provider Training in Eating Disorders (OPTED)
This is a randomized controlled trial for mental health clinicians comparing two methods of training in family-based treatment (FBT) for restrictive eating disorders.
- Trial name
- OPTED (NCT05389657)
- Testing
- Web-based training, Live training
- Where
- United States
- Volunteers
- 85 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Anorexia of Ageing
Impaired Regulation of Energy Balance in Elderly People (Balance Study)
Over the past century life expectancy has risen rapidly. As a result, the proportion of elderly people continues to grow. Elderly people probably have an impaired regulation of energy balance (energy intake versus energy…
- Trial name
- Balance (NCT00561145)
- Testing
- Energy restriction period
- Where
- Netherlands
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Wageningen University
Non-small Cell Lung Cancer, Cachexia
Non-interventional Study to Assess the Frequency of Cachexia in Patients With Non-small Cell Lung Cancer.
The purpose of this study is to assess the frequency of cachexia and the management of cachexia and associated symptoms in a patient population with non-small cell lung cancer (NSCLC).
- Trial name
- CacheMire (NCT02968979)
- Where
- France
- Volunteers
- 539 people
- Sponsor
- Chugai Pharma France
Anorexia Nervosa
Trial of Quetiapine in Anorexia Nervosa
This research study is being held at UCSD to determine whether the medication Quetiapine helps people suffering from anorexia nervosa by reducing core eating disorders symptoms.
- Trial name
- NCT00518973
- Testing
- Quetiapine
- Where
- United States
- Volunteers
- 21 people
- Sponsor
- University of California, San Diego
Weight Loss, Weight Gain
Eating Mindfully to Prevent Weight Regain
The overall objective of this study is to evaluate the efficacy of a mindfulness-based intervention to prevent weight regain in weight-reduced adults.
- Conditions
- Weight Loss, Weight Gain, Eating Behavior, Obesity
- Trial name
- EMPWR (NCT04847843)
- Testing
- Mindfulness Orientated Recovery Enhancement, Control Intervention
- Where
- United States
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- University of Utah
Obesity
Use of Medication to Improve Weight Loss in Suboptimal Early Responders to Behavioral Treatment
This is a two-phase study. Phase 1 will evaluate obesity-related behavioral and biological characteristics as potential predictors of response to behavioral treatment (BT) for weight loss.
- Trial name
- NCT03779048
- Testing
- Behavioral Treatment, Phentermine 15 MG
- Where
- United States
- Volunteers
- 147 people
- Sponsor
- University of Pennsylvania
Anorexia Nervosa
Safety Profile of Insulin Like Growth Factor-1 (IGF-I) Administration in Adolescents
The purpose of this study was to determine whether giving insulin like growth factor-I (IGF-I) to adolescent low weight girls is safe and whether this increases levels of bone formation markers.
- Trial name
- NCT00516386
- Testing
- RhIGF-1
- Where
- United States
- Volunteers
- 16 people
- Sponsor
- Massachusetts General Hospital
Undernutrition, Wasting
Evaluating Oral Nutritional Supplements on Children's Nutritional Status and Digestive Health in Vietnam.
Evaluating the efficiency of using Oral Nutritional Supplementation toward nutrition status (anthropometric index, the prevalence of wasting), digestive disorders, and anorexic in children aged 24 - 71 months.
- Conditions
- Undernutrition, Wasting, Malnourished
- Trial name
- NCT05551637
- Testing
- Kazu Gain Gold
- Where
- Vietnam
- Volunteers
- 600 people
- Sponsor
- Tu Nguyen Song
Anorexia Nervosa
PET Imaging Study of Recovered Anorexics
Several studies in the past suggest that individuals who have or had anorexia nervosa may have alterations in brain serotonin. Serotonin seems to play an important role in regulating anxiety, mood, and other symptoms found in…
- Trial name
- NCT00603018
- Testing
- Fluoxetine
- Where
- United States
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- University of Pittsburgh
Anorexia Nervosa
Olanzapine in the Treatment of Patients With Anorexia Nervosa
The purpose of the study is to evaluate the efficacy of an anti-psychotic medication, Olanzapine, in achieving desired weight gain in patients identified as having Anorexia Nervosa, either restricting or binge/purge subtype.
- Trial name
- NCT00260962
- Testing
- Olanzapine, Day Hospital
- Where
- Canada
- Volunteers
- 34 people
- Sponsor
- Ottawa Hospital Research Institute
Anorexia Nervosa, Atypical Anorexia Nervosa
Parent Emotion Coaching for Anorexia Nervosa
Family based treatment (FBT) is the evidence based treatment for pediatric anorexia nervosa (AN), but 50% of adolescents do not respond and the consequences for non-response are dire (e.g., 11.5% mortality rate).
- Trial name
- NCT04421989
- Testing
- Emotion Coaching, Support Group
- Where
- United States
- Volunteers
- 41 people, healthy volunteers welcome
- Sponsor
- Children's Hospital Medical Center, Cincinnati
Eating Disorders
Effectiveness of Atypical Antipsychotic Medication for Outpatients With Anorexia Nervosa
This study will compare the effectiveness of two atypical antipsychotic medications, olanzapine and aripiprazole, in treating people with anorexia nervosa.
- Trial name
- NCT00685334
- Testing
- Olanzapine, Aripiprazole
- Where
- 2 sites in United States, Canada
- Volunteers
- 22 people
- Sponsor
- New York State Psychiatric Institute
Weight Loss
ELIRA 2: Safety and Effectiveness of TENS Assisted Weight Loss and Appetite Suppression
The objectives of this study are to demonstrate safety and effectiveness of a wearable patch TENS system (Appendix 2) in driving weight loss and appetite suppression when coupled with an integrated weight loss reduction strategy.
- Trial name
- ELIRA_2 (NCT03936699)
- Testing
- Transcutaneous Nerve Stimulator (TENS), Diet & Exercise
- Where
- United States
- Volunteers
- 161 people
- Sponsor
- Elira Therapeutics, Inc.
Anorexia Nervosa
Helping HAND: Healing Anorexia Nervosa Digitally
The proposed project will develop and pilot a coached mobile app, including a social networking component, for individuals with anorexia nervosa to use in the post-acute period
- Trial name
- NCT05499676
- Testing
- SilverCloud Health Mobile Intervention, Social Networking Intervention: Facebook
- Where
- 3 sites in United States
- Volunteers
- 90 people
- Sponsor
- Washington University School of Medicine
Anorexia Nervosa, Osteoporosis
The Role of Parathyroid Hormone (PTH) in Low Bone Mass in Anorexia Nervosa
Decreased bone strength is a common and serious medical problem present in many women with anorexia nervosa, or disordered eating.
- Trial name
- NCT00759772
- Testing
- Teriparatide
- Where
- United States
- Volunteers
- 23 people
- Sponsor
- Massachusetts General Hospital
Pulmonary Disease, Chronic Obstructive (COPD)
Inspiratory Flow Rates Achieved by the COPD Patients Through Breezhaler®, Ellipta® and Handihaler® Inhaler Devices
The purpose of this study was to compare dynamic inspiratory flow rates achieved by a population of Chronic Obstructive Pulmonary Disease (COPD) patients through the Breezhaler®, Ellipta® and Handihaler® dry powder inhaler (DPI)…
- Trial name
- NCT02596009
- Testing
- Breezhaler®, Ellipta®, Handihaler®
- Where
- 5 sites in Argentina
- Volunteers
- 97 people
- Sponsor
- Novartis Pharmaceuticals
Cachexia, Non-Small-Cell Lung Cancer
Study to Assess the Safety and Tolerability of Repeated Doses of an Investigational New Drug in Patients With Cancer and Cachexia.
Study to assess the safety and tolerability of repeated doses of an investigational new drug in patients with cancer and cachexia.
- Conditions
- Cachexia, Non-Small-Cell Lung Cancer, Pancreatic Cancer, Colorectal Cancer
- Trial name
- NCT04299048
- Testing
- PF-06946860
- Where
- 10 sites in United States
- Volunteers
- 11 people
- Sponsor
- Pfizer
Anorexia Nervosa, Bulimia Nervosa
App-Based Mindfulness Training for Individuals With Anorexia Nervosa and Bulimia Nervosa
We will evaluate the acceptability and feasibility of a 8-week long digital mindfulness-based intervention for anorexia nervosa and bulimia nervosa.
- Conditions
- Anorexia Nervosa, Bulimia Nervosa, Anorexia Nervosa, Atypical, Bulimia; Atypical
- Trial name
- NCT05753410
- Testing
- Mindful Courage
- Where
- United States
- Volunteers
- 32 people
- Sponsor
- Yeshiva University