Clinical trials: Apraxias
Rolandic Epilepsy, Apraxia
Scholar Performance and Praxis Assessment in Children With Rolandic Epilepsy
Rolandic Epilepsy is the most common form of childhood epilepsy. It is classified as idiopathic, age-related epilepsy syndrome with benign evolution.
- Trial name
- NCT01046760
- Testing
- Language Assessment
- Where
- Brazil
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Campinas, Brazil
Gait Apraxia, Alzheimer Disease
Gait and Alzheimer Interaction Tracking (GAIT) Study
The purpose of this study is to examine and to compare gait characteristics under single- and dual-task conditions among healthy subjects together with AD patients at different stages of disease (i.e., pre-dementia, mild and…
- Conditions
- Gait Apraxia, Alzheimer Disease, Impaired Cognition, Cerebral Atrophy
- Trial name
- GAIT (NCT01315717)
- Where
- France
- Volunteers
- 912 people, healthy volunteers welcome
- Sponsor
- University Hospital, Angers
Deep Brain Stimulation, Parkinson Disease
Apraxia in Parkinson's Disease Patients With Deep Brain Stimulation
Deep brain stimulation (DBS) of the subthalamic nucleus or globus pallidus internus can improve motor symptoms Parkinson's disease (PD).
- Conditions
- Deep Brain Stimulation, Parkinson Disease, Apraxia, Motor
- Trial name
- Apraxia DBS (NCT04725773)
- Testing
- Deep brain stimulation effect on apraxia
- Where
- United States
- Volunteers
- 2 people
- Sponsor
- University of Florida
Osteoarthritis
Minimally Invasive Total Knee Replacement - Navigated Versus Non-navigated Study
The primary objective of this investigation is to compare the precision of long leg alignment achieved by the two types of procedure.
- Trial name
- NCT00733330
- Testing
- Either P.F.C. Sigma or L.C.S. Complete knee replacement using the conventional surgical approach and manual surgical technique, Either P.F.C. Sigma or L.C.S. Complete knee replacement using minimally invasive surgical approach and computer navigation
- Where
- 5 sites in United States, Australia and 1 more
- Volunteers
- 86 people
- Sponsor
- DePuy International
Apraxia of Speech, Non-fluent Aphasia
The Neurobiology of Two Distinct Types of Progressive Apraxia of Speech
The purpose of this study is to identify and distinguish two different types of Progressive Apraxia of Speech through clinical imaging and testing.
- Conditions
- Apraxia of Speech, Non-fluent Aphasia, Primary Progressive Aphasia, Primary Progressive Nonfluent Aphasia
- Trial name
- SLD4T (NCT03313011)
- Testing
- Testing protocol for the study
- Where
- United States
- Volunteers
- 47 people
- Sponsor
- Mayo Clinic
Alzheimer's Disease, Gait Apraxia
Alzheimer's Disease and Related Disorders
The purpose of this study is to compare characteristics of gait and balance measured among patients with Alzheimer's disease or related disorders separated into 3 groups according to the stage of disease (i.e., pre-dementia, mild…
- Conditions
- Alzheimer's Disease, Gait Apraxia, Impaired Cognition
- Trial name
- MERE (NCT01315704)
- Testing
- Drug intervention
- Where
- France
- Volunteers
- 700 people, healthy volunteers welcome
- Sponsor
- University Hospital, Angers
Corticobasal Syndrome
Electrical Polarization of the Brain in Corticobasal Syndrome
This study will test whether DC electrical polarization of the brain can temporarily improve hand function in patients with corticobasal syndrome (CBS).
- Trial name
- NCT00273897
- Testing
- Phoresor II
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- National Institute of Neurological Disorders and Stroke (NINDS)
Performance Anxiety, Emotional Stress
Intervention on Caregivers Caring for Patients Poststroke With Upper Limb Apraxia
The purpose of this study is to analyze the effects of a intervention on a specific health prevention/intervention program aimed at caregivers of mild and moderate patients post stroke with upper limb apraxia in comparison to a…
- Trial name
- CPA (NCT02307019)
- Testing
- Program on specific prevention of health, Program on general prevention of health
- Where
- Spain
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Universidad de Granada
Cerebral Palsy, Hydrocephalus
Expanded Access Protocol: Umbilical Cord Blood Infusions for Children With Brain Injuries
This protocol is designed to enable access to intravenous infusions of banked umbilical cord blood (CB), that is thawed and not more than minimally manipulated, for children with various brain disorders.
- Conditions
- Cerebral Palsy, Hydrocephalus, Apraxia of Speech, Hypoxia Ischemia, Cerebral
- Trial name
- NCT03327467
- Testing
- Cord Blood Infusion
- Where
- United States
- Sponsor
- Joanne Kurtzberg, MD
Stroke, Apraxias
Functional Rehabilitation of Upper Limb Apraxia in Patients Poststroke
The purpose of this study is to analyze the effects of a mixed intervention of occupational therapy (rehabilitative and compensatory approach) at home to upper limb apraxia in mild and moderate patients post stroke in comparison…
- Trial name
- NCT02199093
- Testing
- Functional Rehabilitation of apraxia, Traditional health educative protocol
- Where
- Spain
- Volunteers
- 40 people
- Sponsor
- Universidad de Granada
Childhood Apraxia of Speech
Treatment of Cantonese Speakers With Childhood Apraxia of Speech
The proposed study aims to investigate the efficacy of the Dynamic Temporal and Tactile Cueing treatment in Cantonese-English bilingual speakers with childhood apraxia of speech.
- Trial name
- NCT06385470
- Testing
- Dynamic Temporal and Tactile Cueing treatment
- Where
- Hong Kong
- Volunteers
- 4 people
- Sponsor
- The Hong Kong Polytechnic University
Carotid Artery Stenoses
SPI-guided Analgesia During CEA Under RA
The aim of this randomized prospective trial is to assess the utility of Adequacy of Anaesthesia technique (Response Entropy and Surgical Pleth Index) for monitoring pain perception intraoperatively, maintainance of hemodynamic…
- Trial name
- CEA (NCT04500249)
- Testing
- infiltration rescue intraoperative analgesia, rescue IA, rescue antyhypertensive medication
- Where
- Poland
- Volunteers
- 105 people
- Sponsor
- Medical University of Silesia
PPA, Primary Progressive Aphasia
PiB PET Scanning in Speech and Language Based Dementias
The study is designed to determine whether there are clinical features that can be used as biomarkers to predict whether underlying Alzheimer's pathology is the cause of a speech and language based dementia.
- Conditions
- PPA, Primary Progressive Aphasia, Aphasia, Non-fluent Aphasia
- Trial name
- NCT01623284
- Testing
- C-11 PiB, F-18 FDG
- Where
- United States
- Volunteers
- 168 people
- Sponsor
- Mayo Clinic
Aphasia, Stroke
Brain Biomarkers of Response to Treatment for Apraxia of Speech
The study will use MRI brain imaging to identify brain changes associated in stroke patients after they receive speech-language treatment for their speech difficulties.
- Trial name
- SPT (NCT02046941)
- Testing
- Speech Production Treatment
- Where
- United States
- Volunteers
- 17 people
- Sponsor
- VA Office of Research and Development
Nonfluent Aphasia, Progressive, Primary Progressive Nonfluent Aphasia
tDCS and Speech Therapy for Motor Speech Disorders Caused by FTLD Syndromes: a Feasibility Study
The investigators will test the feasibility of using transcranial direct current stimulation (tDCS) and speech therapy to treat participants with motor speech disorders caused by Frontotemporal Lobar Degeneration Pathology…
- Conditions
- Nonfluent Aphasia, Progressive, Primary Progressive Nonfluent Aphasia, Primary Progressive Non Fluent Aphasia, Progressive Supranuclear Palsy
- Trial name
- NCT04883229
- Testing
- Halo Neuroscience Neurostimulator
- Sponsor
- University of California, San Francisco
Cerebral Palsy, Dyspraxia
Immersive Virtual Environments and Wearable Haptic Devices in Rehabilitation of Children With Neuromotor Impairments
The investigators proposed a controlled, single-blind, unicentric, crossover, randomized, clinical trial to test the effects of immersive virtual environments and wearable haptic devices in the rehabilitation of children with…
- Trial name
- SERIOUSGAME (NCT03353623)
- Testing
- Serious Game, Conventional Therapy
- Where
- Italy
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- Scuola Superiore di Studi Universitari e di Perfezionamento Sant'Anna
Ideomotor Apraxia
EEG and EMG Analysis of Ideomotor Apraxia
This study will examine how the brain operates during execution and control of voluntary movement and what goes wrong with these processes in disease.
- Trial name
- NCT00024999
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- National Institute of Neurological Disorders and Stroke (NINDS)
Speech Sound Disorder, Apraxia of Speech
Efficacy of an Intervention for the Children With Severe Speech Sounds Disorders
Speech sound disorders (SSDs) is one type of communication problems in children. It is a board term describing different difficulties that impact speech intelligibility.
- Conditions
- Speech Sound Disorder, Apraxia of Speech, Developmental Verbal Dyspraxia
- Trial name
- NCT03700151
- Testing
- Treatment for Children with Severe Speech Sound Disorders
- Where
- Hong Kong
- Volunteers
- 20 people
- Sponsor
- Chinese University of Hong Kong
Lumbar Disc Disease
SPI-directed Analgesia for Lumbar Discectomy
The aim of this randomized trial is to assess the efficacy of analgesia for lumbar discectomy and compare Numerical Rating Scale (NRS) with Surgical Pleth Index (SPI) for monitoring pain perception postoperatively.
- Trial name
- SPI (NCT02971540)
- Testing
- Metamizol, Tramadol, Bupivacaine
- Where
- Poland
- Volunteers
- 132 people
- Sponsor
- Medical University of Silesia
Childhood Apraxia of Speech
The Effects of Caregiver Training on DTTC Treatment Outcomes in CAS
The goal of this clinical trial is to investigate the impact of direct vs. indirect caregiver training on treatment outcomes following a period of Dynamic Temporal and Tactile Cueing (DTTC) intervention combined with home…
- Trial name
- DTTC (NCT05916222)
- Testing
- Dynamic Temporal and Tactile Cueing (DTTC)
- Where
- 2 sites in United States
- Volunteers
- 40 people
- Sponsor
- New York University