Clinical trials: Arrhythmia, Cardiac
Ventricular Tachycardia (VT)
Ventricular Tachycardia Ablation Through Radiation Therapy Consortium: Concept Description of an Observational Retrospective Multicentric Trial
Recurrent ventricular tachycardia (VT) is a potentially life-threatening arrhythmia in patients with structural heart disease. Despite the use of antiarrhythmic drugs, implantable cardioverter-defibrillators (ICDs), and…
- Trial name
- VT-ART R (NCT06990139)
- Where
- Italy
- Volunteers
- 149 people
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Atrial Fibrillation and Flutter, Valvular Heart Disease
Canadian EdoxAban(Lixiana®) Registry in Patients With ATrial Fibrillation/Flutter With Confirmed ValvUlar HeaRt DiseasE
The objective of this registry is the characterization of patients with atrial fibrillation (AF) and/ or atrial flutter (AFL) with confirmed VHD who are prescribed edoxaban in a real life clinical setting.
- Trial name
- CAPTURE (NCT03488420)
- Testing
- Edoxaban Pill
- Where
- 9 sites in Canada
- Volunteers
- 136 people
- Sponsor
- Montreal Heart Institute
Stroke
Finding Atrial Fibrillation in Stroke - Evaluation of Enhanced and Prolonged Holter Monitoring
The purpose of this study is to assess whether repeated enhanced and prolonged ECG monitoring after ischemic stroke results in a higher detection of atrial fibrillation (/flutter) compared to usual care (at least 24 hour of…
- Trial name
- NCT01855035
- Testing
- prolonged ECG monitoring, standard care
- Where
- 4 sites in Germany
- Volunteers
- 402 people
- Sponsor
- Institut fuer anwendungsorientierte Forschung und klinische Studien GmbH
Ventricular Tachycardia
INTERVENE: Indian Trial of Endocardial Ventricular Substrate Ablation to Prevent Recurrent VT Events
This study to is being conducted in India to determine the role of catheter-based ablation for ventricular tachycardia (VT) in post- heart attack patients who meet established guidelines for implantable cardiodefibrillator (ICD)…
- Trial name
- INTERVENE (NCT02301390)
- Testing
- Amiodarone, Catheter Ablation
- Where
- 3 sites in India
- Volunteers
- 53 people
- Sponsor
- Icahn School of Medicine at Mount Sinai
Covid19, Comorbidities and Coexisting Conditions
Analysis of Health Status of Сomorbid Adult COVID-19 Patients Hospitalised in Second Wave of SARS-CoV-2 Infection
Comparison of COVID-19 disease course in hospitalized patients infected by SARS-CoV-2 in first and second waves of the novel coronavirus infection
- Conditions
- Covid19, Comorbidities and Coexisting Conditions, Risk Factor, Cardiovascular, Death
- Trial name
- ACTIV-2 (NCT04709120)
- Where
- Russia
- Volunteers
- 2,968 people
- Sponsor
- Eurasian Association of Therapists
Atrial Fibrillation
PulseSelect™ PFA Global Registry
The PulseSelect™ PFA Global Registry is a prospective, global, multi-center, observational post-approval study. Subjects will be treated with the PulseSelect™ PFA System and followed according to SOC.
- Trial name
- NCT06393920
- Where
- 43 sites in Australia, Belgium and 14 more
- Volunteers
- 1,950 people
- Sponsor
- Medtronic Cardiac Ablation Solutions
Sinus Node Dysfunction, Atrial Fibrillation
Atrial Fibrillation With Sinus Node Dysfunction: Intensive Device Follow-up
The study will try to access the efficacy of atrial pacing, medication and radiofrequency ablation in treating patients with paroxysmal atrial fibrillation and sinus node dysfunction; to identify the response to these treatments…
- Trial name
- SAFE PAF-SND (NCT03607123)
- Testing
- programing of pacemaker, AF ablation, Anti arryhthmic drugs
- Where
- China
- Volunteers
- 200 people
- Sponsor
- The First Affiliated Hospital with Nanjing Medical University
Paroxysmal Atrial Fibrillation, Atrial Fibrillation
Adjunctive Ganglionated Plexus Ablation in Redo-Pulmonary Vein Isolation
The investigator propose to test the efficacy of adjunctive ET-GP ablation in patients undergoing redo PVI for paroxysmal AF.
- Trial name
- ADD-GP (NCT03535818)
- Testing
- Radiofrequency ablation
- Where
- United Kingdom
- Volunteers
- 68 people, healthy volunteers welcome
- Sponsor
- Imperial College London
Paroxysmal Atrial Fibrillation, Coronary Artery Disease
Surgical Pulmonary Vein Isolation Efficiency Study
A substantial proportion of patients undergoing elective coronary artery bypass grafting have a history of paroxysmal atrial fibrillation. Paroxysmal atrial fibrillation has adverse short-and long term postoperative effects.
- Trial name
- FIN-PVI (NCT01791218)
- Testing
- CABG, AVR or CABG+AVR and PVI, CABG, AVR or CABG+AVR
- Where
- Finland
- Volunteers
- 2 people
- Sponsor
- Kuopio University Hospital
Atrial Fibrillation
Evaluation of the Safety and Performance of the Very High Power-Short Duration QDOT
The aim of the present study is to compare the safety and short-term performance between THERMOCOOL SMARTTOUCH SF-5D QDOT system used with fast ablation mode and the standard Thermocool Smartouch SF in treatment of patients with…
- Trial name
- NCT04592497
- Testing
- AF ablation
- Where
- Israel
- Volunteers
- 60 people
- Sponsor
- Tel-Aviv Sourasky Medical Center
Atrial Fibrillation
Evaluation of Treatment Safety in Patients With Atrial Fibrillation on Edoxaban Therapy in Real-Life in Turkey
This is a national, multi-center, prospective study to evaluate the safety of Edoxaban in patients diagnosed with AF who are currently using Edoxaban for stroke prevention.
- Trial name
- ETAF-TR (NCT04594915)
- Testing
- Edoxaban
- Where
- 45 sites in Turkey (Türkiye)
- Volunteers
- 1,053 people
- Sponsor
- Daiichi Sankyo Turkey, a Daiichi Sankyo Company
Tachycardia, Ventricular
S-ICD® System IDE Clinical Study
This clinical study is designed to evaluate the safety and effectiveness of the subcutaneous implantable defibrillator (S-ICD) System.
- Trial name
- NCT01064076
- Testing
- S-ICD System
- Where
- 33 sites in United States, Netherlands and 2 more
- Volunteers
- 330 people
- Sponsor
- Boston Scientific Corporation
Atrial Fibrillation
Postoperative Atrial Fibrillation Suppression By Nerve Stimulation
The current study will evaluate the potential of stimulating the R.auricularis of the vagus nerve located at the Fossa triangularis to ameliorate or suppress AF in the study Population!
- Trial name
- NCT03533140
- Testing
- DUCEST Neurostimulator V Group A, DUCEST Neurostimulator V Group B
- Volunteers
- 42 people
- Sponsor
- Medical University of Vienna
Atrial Fibrillation
Concomitant Epicardial Pulmonary Vein Isolation in Patients With Atrial Fibrillation Undergoing Elective Cardiac Surgery
Recent studies demonstrated that radiofrequency isolation of the pulmonary veins (PVI) is a superior alternative to antiarrhythmic drug therapy in patients with symptomatical paroxysmal atrial fibrillation (AF).
- Trial name
- CONTROL-AF (NCT01360918)
- Testing
- Epicardial pulmonary vein isolation, Usual care
- Where
- Netherlands
- Volunteers
- 2 people
- Sponsor
- Medisch Spectrum Twente
Ventricular Tachycardia
Late Potentials and Ablation Index in Ventricular Tachycardia Ablation
There is an increasing evidence regarding the efficacy of a substrate-based ablation approach to ventricular tachycardia (VT). This approach involves identifying regions of scar and also areas displaying late potentials and…
- Trial name
- NCT03437408
- Testing
- Mapping and ablation
- Where
- United Kingdom
- Volunteers
- 15 people
- Sponsor
- University Hospital Southampton NHS Foundation Trust
Ischemic Heart Disease
Arrhythmia in on Pump vs. Off Pump Coronary Artery Bypass Grafting
The aim of this research is to know the incidence of arrhythmias in on vs. off pump CABG and to know their relations to the patient's morbidity and mortality, hospital stay and hospital costs.
- Trial name
- NCT04093817
- Testing
- cardio pulmonary bypass machine
- Volunteers
- 50 people
- Sponsor
- Assiut University
Atrial Arrhythmia, Atrial Fibrillation
VOLT-AF IDE Clinical Study
This clinical investigation is intended to demonstrate safety and effectiveness of the Volt™ Pulsed Field Ablation (PFA) Catheter Sensor Enabled™, the Volt™ PFA Generator, Agilis™ NxT Steerable Introducer Dual-Reach™, and EnSite™…
- Conditions
- Atrial Arrhythmia, Atrial Fibrillation, Paroxysmal Atrial Fibrillation, Persistent Atrial Fibrillation
- Trial name
- NCT06223789
- Testing
- Pulsed Field Ablation
- Where
- 40 sites in United States, Australia and 9 more
- Volunteers
- 392 people
- Sponsor
- Abbott Medical Devices
Atrial Fibrillation
Effects of Fish Oil on Post Ablation Arrhythmias
To determine if peri-operative treatment with omega-3 fatty acids is associated with a decrease in the incidence of early recurrences of atrial arrhythmias (within 30 days) and an improvement in probability of long-term…
- Trial name
- NCT00791089
- Testing
- LOVAZA Omega 3-acid ethyl esters, LOVAZA
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- University of Michigan
Atrial Fibrillation
Russian National Registry of LAAO
The first Russian registry presents data from two hundred consecutive patients with nonvalvular atrial fibrillation, who undergone left atrial appendage occlusion (LAAO) using the Watchman device and the Amplatzer cardiac plug.
- Trial name
- NCT04322474
- Testing
- Catheter-based left atrial appendage occlusion
- Volunteers
- 200 people
- Sponsor
- National Research Center for Preventive Medicine
Bradycardia
Heart Rate Changes Following the Administration of Sugammadex
This a prospective study when the clinician decides to use sugammadex, heart rate will be recorded every minute for 15 minutes following its administration.
- Trial name
- NCT03294018
- Testing
- Recording heart rate changes
- Where
- United States
- Volunteers
- 276 people
- Sponsor
- Joseph D. Tobias