Clinical trials: Arrhythmia Atrial
Atrial Fibrillation, Arrhythmias, Cardiac
Apple Heart Study: Assessment of Wristwatch-Based Photoplethysmography to Identify Cardiac Arrhythmias
The Apple Heart Study (AHS) is a research study conducted to evaluate whether the Apple Heart Study App can use data collected on the Apple Watch to identify irregular heart rhythms, including those from potentially serious heart…
- Conditions
- Atrial Fibrillation, Arrhythmias, Cardiac, Atrial Flutter
- Trial name
- NCT03335800
- Testing
- Apple Heart Study App
- Where
- United States
- Volunteers
- 419,927 people, healthy volunteers welcome
- Sponsor
- Apple Inc.
Atrial Fibrillation
RAFF4 Trial: Vernakalant vs. Procainamide for Acute Atrial Fibrillation in the Emergency Department
The objective is to compare IV vernakalant to IV procainamide for the ED management of acute AF patients. If vernakalant proves to be more effective, faster, and safer than IV procainamide, this will give clinicians an important…
- Trial name
- NCT04485195
- Testing
- Vernakalant, Procainamide
- Where
- 14 sites in Canada
- Volunteers
- 350 people
- Sponsor
- Ottawa Hospital Research Institute
Atrial Fibrillation
Validation Durability Adenosine Effect in Verification Pulmonary Vein Isolation
Adenosine is used clinically to assess permanency of electrical isolation of pulmonary veins during atrial fibrillation ablation, however, the methodology has not been validated either in terms of the reproducibility of the…
- Trial name
- NCT01590875
- Testing
- Adenosine arm
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Medical College of Wisconsin
Atrial Fibrillation, Congestive Heart Failure
Investigational Device Exemption (IDE) Study for the Approval of Closed Loop Stimulation (CLS) and Cardiac Resyncronization Pacing Therapies (CRT) for the Treatment of Atrial Fibrillation (AF) With Ablate and Pace
The purpose of this study is to demonstrate the safety and effectiveness of biventricular pacing over conventional right ventricular pacing in patients with persistent or permanent, symptomatic atrial fibrillation undergoing…
- Trial name
- AVAIL (NCT00356057)
- Testing
- Protos DR/CLS and Stratos LV CRT pacemakers
- Where
- 10 sites in United States
- Volunteers
- 153 people
- Sponsor
- Biotronik, Inc.
Atrial Fibrillation
Safety and Effectiveness Evaluation of the Multi-Electrode Radiofrequency Balloon Catheter for the Treatment of Symptomatic Paroxysmal Atrial Fibrillation
The primary objective of this clinical investigation is to demonstrate safety and effectiveness of the Multi-Electrode RF Balloon catheter for the treatment of drug refractory symptomatic paroxysmal atrial fibrillation.
- Trial name
- STELLAR (NCT03683030)
- Testing
- Multi-Electrode RF Balloon Catheter
- Where
- 41 sites in United States, China and 1 more
- Volunteers
- 397 people
- Sponsor
- Biosense Webster, Inc.
Atrial Fibrillation
CareLink Express (CLE Research)
The primary objective of this research is to determine if evaluating CIEDs using CareLink Express® can lead to shorter time to interrogation in the Emergency Department compared to evaluation of devices using traditional…
- Trial name
- CLE (NCT03223207)
- Volunteers
- 60 people
- Sponsor
- Baylor Research Institute
Atrial Fibrillation
Treatment of Atrial Fibrillation by Minimal Invasive Surgery
The purpose of this study is to determine the feasability of a new epicardial and minimal invasive ablation technique of the left atrium isolating the pulmonary veins for prevention of atrial fibrillation recurrences in patients…
- Trial name
- ABOLISH-AF (NCT00448656)
- Testing
- ablation of pulmonary veins by video assisted thoracic surgery
- Where
- Netherlands
- Volunteers
- 15 people
- Sponsor
- University Medical Center Groningen
Atrial Fibrillation, Arrhythmias, Cardiac
Wearable Cardiac Monitor to Enhance Detection of Arrhythmia Recurrence After Catheter Ablation of Atrial Fibrillation
The WEAR-AF study is a prospective, multicenter clinical trial designed to evaluate the efficacy of wearable technology in the detection, monitoring, and management of atrial fibrillation (AF).
- Conditions
- Atrial Fibrillation, Arrhythmias, Cardiac, Heart Diseases, Cardiovascular Diseases
- Trial name
- WEAR-AF (NCT06564012)
- Volunteers
- 100 people
- Sponsor
- Sunnybrook Health Sciences Centre
Atrial Fibrillation, Diastolic Dysfunction
Atrial Fibrillation: Chronic Beta-blocker Use Versus As-needed Rate Control Guided by Implantable Cardiac Monitor
The goal of this study is to test the feasibility of guiding as-needed pharmacological rate control of atrial fibrillation (AF) by implantable cardiac monitors and to assess the impact of continuous beta-blocker therapy versus…
- Conditions
- Atrial Fibrillation, Diastolic Dysfunction, HFpEF - Heart Failure With Preserved Ejection Fraction
- Trial name
- NCT05745337
- Testing
- As needed pharmacological rate control with beta-blocker (metoprolol tartrate, metoprolol succinate) or calcium channel blocker (diltiazem, verapamil)
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- University of Vermont
Atrial Fibrillation
Recurrence of Arrhythmias After Pulmonary Veins Isolation Detected by ICM
Post Marketing study, Interventional, Prospective, non randomised Describe how the MD is using the information of the ICM in addition of standard FU(clinical exam and holter 24h)post AF ablation(1 year FU).
- Trial name
- RAPID XT (NCT00789139)
- Testing
- ICM Implantation
- Where
- France
- Volunteers
- 47 people
- Sponsor
- Dr Ange FERRACCI
Paroxysmal Atrial Fibrillation.
Atrial Fibrillation: Ablation or Surgical Treatment II: FAST II
The purpose of this study is to compare two invasive treatments of symptomatic paroxysmal atrial fibrillation: Percutaneous radiofrequency catheter ablation and mini invasive thoracoscopic radiofrequency ablation in patients…
- Trial name
- NCT01336075
- Testing
- Percutaneous radiofrequency catheter ablation, Mini invasive thoracoscopic radiofrequency ablation
- Where
- 3 sites in Denmark, Netherlands
- Volunteers
- 26 people
- Sponsor
- Aalborg University Hospital
Atrial Fibrillation, Quality of Life
Evaluation of the Added Value of an Internet-based Educational Program for Patients With Atrial Fibrillation.
This study is prospective, open and randomized concerning the value of an Internet-based educational program for patients with atrial fibrillation compared to "care as usual".
- Conditions
- Atrial Fibrillation, Quality of Life, Signs and Symptoms, Health Economy
- Trial name
- AMADEUS (NCT03763500)
- Testing
- Internet-based education
- Where
- 3 sites in Sweden
- Volunteers
- 200 people
- Sponsor
- Ulla Walfridsson
Atrial Fibrillation
Patient Perception of MultiPulse Therapy™ (MPT™)
Assess the subject acceptance of MPT, using therapy parameters that have been shown to be effective in terminating episodes of atrial fibrillation.
- Trial name
- NCT04939584
- Testing
- MultiPulse Therapy
- Where
- 2 sites in Australia
- Volunteers
- 6 people
- Sponsor
- Cardialen, Inc.
Tachyarrhythmia, Atrial Flutter
MCG for Localization of Tachyarrhythmia's Origin
This is an exploratory research aiming to accurately identify the site of origin of tachyarrhythmia using Magnetocardiography (MCG), which will have guiding significance for early diagnosis, the formulation of treatment plans and…
- Conditions
- Tachyarrhythmia, Atrial Flutter, Paroxysmal Supraventricular Tachycardia, Atrial Tachycardia
- Trial name
- NCT06327425
- Testing
- Magnetocardiography
- Where
- China
- Volunteers
- 1,000 people
- Sponsor
- Qilu Hospital of Shandong University
Atrial Arrhythmia, Intracardiac Echocardiography
A Study on the Acquisition of 2D ICE Images With the CHORUS IDx System in Subjects Undergoing an Ablation Procedure
A first-in-human prospective data collection study including subjects who are planned to undergo an ablation procedure for any atrial arrhythmia as per medical judgement and the site's standard practice, represents the most…
- Trial name
- SONAR-ICE (NCT07353710)
- Testing
- ICE Image Acquisition
- Where
- 8 sites in Australia, Croatia and 6 more
- Volunteers
- 200 people
- Sponsor
- Boston Scientific Corporation
Atrial Fibrillation
Use of Volta Medical AI-software During Atrial Fibrillation Ablation to Identify Patients Who May Need More Than Pulmonary Vein Isolation.
DISPLAY-AF is a prospective, multicenter, single-arm post-market clinical follow-up investigation designed to evaluate whether spatiotemporal dispersion areas identified by the Volta AF-Xplorer II artificial intelligence (AI)…
- Trial name
- DISPLAY-AF (NCT07807423)
- Testing
- Complete biatrial mapping
- Where
- 5 sites in France
- Volunteers
- 125 people
- Sponsor
- Volta Medical
Stroke, Atrial Fibrillation
Differences in ECG- vs. proLonged cardIac MonItor-DeTected Atrial Fibrillation in STROKE Patients (DELIMIT AF-STROKE)
The present study is an investigator-initiated, single-center, retrospective study based on data from the London Ontario Stroke Registry (LOSR), aiming to compare the characteristics and outcomes of ECG-detected and…
- Conditions
- Stroke, Atrial Fibrillation, TIA
- Trial name
- NCT05822791
- Testing
- Prolonged cardiac monitoring, ECG
- Where
- Canada
- Volunteers
- 366 people
- Sponsor
- Luciano A. Sposato
Cardiovascular Disease Other
CARDIOVASCular Unexpected fiNdings in patiEnts Undergoing eXecution of PET/tc
The goal of this single-center observational study is to retrospectively evaluate incidental findings at the cardiovascular level in a selection of patients referred to the O.U.
- Trial name
- CV-UNEXPET/TC (NCT06774391)
- Where
- Italy
- Volunteers
- 1,000 people
- Sponsor
- IRCCS Azienda Ospedaliero-Universitaria di Bologna
Atrial Fibrillation (AF), Cardiovascular Diseases
Low-Intensity Focused Ultrasound Targeting the Stellate Ganglion for Regulating Autonomic Nerve Function and Sleep Quality in Perioperative Patients With Cardiovascular Diseases
The goal of this multicenter, double-blind, randomized controlled trial is to evaluate the efficacy and safety of low-intensity focused ultrasound (LIFU) stellate ganglion modulation for improving autonomic function and sleep…
- Trial name
- US-REST (NCT07595068)
- Testing
- Low-intensity focused ultrasound (LIFU) targeting the left stellate ganglion
- Where
- 7 sites in China
- Volunteers
- 200 people
- Sponsor
- Renmin Hospital of Wuhan University
Atrial Flutter
The Contact-CTI Study: Use of Tissue Contact Data to Guide Atrial Flutter Ablation
This study will be a single blind prospective randomised control trial in patients undergoing ablation for the treatment of typical atrial flutter, with the aim of investigating the benefit of a new impedance-based computer…
- Trial name
- NCT01596959
- Testing
- Radiofrequency ablation utilising the ECI contact software, Radiofrequency ablation without the use of ECI contact data
- Where
- United Kingdom
- Volunteers
- 101 people
- Sponsor
- Oxford University Hospitals NHS Trust