Clinical trials: Arrhythmias Ventricular
Heart Failure, Atrial Fibrillation
Cardiac Contractility Modulation in Patients With Chronic Heart Failure and the Various Forms of Atrial Fibrillation
Chronic heart failure (CHF) is a global pandemic which affects around 26 million people worldwide and develops in 10% of people over 70 years .
- Conditions
- Heart Failure, Atrial Fibrillation, Left Ventricular Ejection Fraction
- Trial name
- NCT05550792
- Testing
- optimizer smart
- Where
- Russia
- Volunteers
- 200 people
- Sponsor
- National Medical Research Center for Cardiology, Ministry of Health of Russian Federation
Cardiac Arrest, Sudden, Ventricular Tachycardia
Cardiopulmonary Resuscitation Performance of Professional Rescuers With a New Defibrillation Algorithm
In the Paris (France) Medical Emergency system, in the early phase of Out-of-hospital Cardiac Arrest (OHCA), the treatment of a Ventricular Fibrillation (VF) consists of delivering an External Electric Shock (EES) by a rescuer…
- Conditions
- Cardiac Arrest, Sudden, Ventricular Tachycardia, Ventricular Fibrillation, Sudden Cardiac Death
- Trial name
- DEFI-2022 (NCT04691089)
- Where
- France
- Volunteers
- 285 people
- Sponsor
- French Defence Health Service
Bradycardia, Brady-tachy Syndrome
ALPs Single ChambEr New Device
Prospective, non-randomized, multi-center, international study designed to evaluate the initial safety and performance of the ALPS leadless pacemaker when used in patients with bradycardia.
- Conditions
- Bradycardia, Brady-tachy Syndrome, AV Block, Atrial Fibrillation (AF)
- Trial name
- ASCEND (NCT07461935)
- Testing
- Leadless ventricular pacemaker implantation
- Volunteers
- 10 people
- Sponsor
- Cairdac SA
Myocarditis, Ventricular Arrythmia
Role of Endomyocardial Biopsy and Aetiology-based Treatment in Patients With Inflammatory Heart Disease in Arrhythmic and Non-arrhythmic Clinical Presentations: an Integrated Approach for the Optimal Diagnostic and Therapeutic Management
Myocarditis is a complex inflammatory disease, usually occurring secondary to viral infections, autoimmune processes or toxic agents.
- Conditions
- Myocarditis, Ventricular Arrythmia, Inflammatory Cardiomyopathy, Genetic Predisposition
- Trial name
- MYOCAR (NCT04521790)
- Testing
- support treatment, cardiac medical treatment, aetiology-specific treatment, device implant, arrhythmia ablation
- Where
- Italy
- Volunteers
- 1,000 people
- Sponsor
- Scientific Institute San Raffaele
Ventricular Tachycardia
Stereotaxis Idiopathic Ventricular Tachycardia (VT) Study
This study will assess the outcomes of using magnetic navigation to treat ventricular tachycardia (VT) or premature ventricular contractions (PVCs) that occur for unknown reasons and are not related to structural heart disease.
- Trial name
- NCT01401608
- Testing
- RF Ablation
- Where
- United States
- Volunteers
- 6 people
- Sponsor
- Stereotaxis
Ventricular Tachycardia
Ventricular Tachycardia Mechanisms
The purpose of this study is to understand why certain hearts have ventricular arrhythmias and help identify areas of the heart that cause arrhythmias.
- Trial name
- NCT05478213
- Testing
- Monophasic Action Potential (MAP) Catheter
- Where
- 3 sites in United States
- Volunteers
- 10 people
- Sponsor
- Emory University
Acute Respiratory Distress Syndrome
Evaluation of POC Lung Ultrasound Combined With Pressure-volume Curve to Titration Adjust PEEP for ARDS Lung Recruitment
Using lung ultrasound re-aeration score(LUS-RAS) combined with pressure-volume curve(PVC) adjust maintain positive end-expiratory pressure(PEEP) after recruitment maneuver, to achieve real-time adjustment, reduce…
- Trial name
- NCT03076450
- Testing
- Lung Ultrasound, Maximum Oxygenation
- Where
- China
- Volunteers
- 30 people
- Sponsor
- Shanghai Pudong New Area Gongli Hospital
Atrial Fibrillation, Coronary Artery Disease
Prospective Project to Identify Biomarkers of Morbidity and Mortality in Cardiovascular Interventional Patients
The objective of CAREBANK study is to establish definitive relationships with human cardiac samples and clinical phenotypes in patients undergoing cardiac procedures.
- Conditions
- Atrial Fibrillation, Coronary Artery Disease, Aortic Valve Stenosis, Aortic Valve Disease
- Trial name
- CAREBANK (NCT03444259)
- Testing
- Cardiac surgery
- Where
- Finland
- Volunteers
- 1,001 people
- Sponsor
- University of Turku
Paroxysmal Supraventricular Tachycardia
Safety Study of Etripamil Nasal Spray for Patients With Paroxysmal Supraventricular Tachycardia. NODE-303
NODE-303 was a multi-center, open label study to evaluate the safety of etripamil NS in participants with Paroxysmal Supraventricular Tachycardia (PSVT).
- Trial name
- NCT04072835
- Testing
- Etripamil NS
- Where
- 124 sites in United States, Argentina and 3 more
- Volunteers
- 1,116 people
- Sponsor
- Milestone Pharmaceuticals Inc.
Paroxysmal Supraventricular Tachycardia (PSVT)
Efficacy and Safety of Intranasal MSP-2017 (Etripamil) for the Conversion of PSVT to Sinus Rhythm
The primary objective of this study is to demonstrate the superiority of at least 1 dose of intranasal (IN) MSP-2017 (Etripamil) over placebo in terminating PSVT induced in an electrophysiology (EP) laboratory.
- Trial name
- NODE-1 (NCT02296190)
- Testing
- Etripamil
- Where
- 30 sites in United States, Canada
- Volunteers
- 199 people
- Sponsor
- Milestone Pharmaceuticals Inc.
Focal Ventricular Arrhythmias, Premature Ventricular Contractions
Treatment of Focal Ventricular Tachycardias Using a Pulsed Field Ablation From a Point Ablation Catheter Short Title FOCUS-PFA
The purpose of this study is to examine the use of a point ablation catheter (Farapoint, Boston Scientific) in the mapping and ablation of focal ventricular arrhythmias (premature ventricular contractions or ventricular…
- Conditions
- Focal Ventricular Arrhythmias, Premature Ventricular Contractions, Ventricular Tachycardias
- Trial name
- FOCUS PFA (NCT06747013)
- Testing
- Point Ablation Catheter
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Vivek Reddy
Ventricular Tachycardia, Ventricular Fibrillation
DATAS: The Dual Chamber & Atrial Tachyarrhythmias Adverse Events Study
The Dual Chamber \& Atrial Tachyarrhythmias Adverse Events Study (DATAS) was designed to analyze the ability of dual chamber ICDs, to reduce clinically significant adverse events as compared to single chamber ICD in a non…
- Conditions
- Ventricular Tachycardia, Ventricular Fibrillation, Defibrillators, Implantable
- Trial name
- DATAS (NCT00157820)
- Testing
- Single Chamber Implantable Cardioverter Defibrillator, Dual Chamber implantable cardioverter defibrilator
- Volunteers
- 354 people
- Sponsor
- Medtronic Cardiac Rhythm and Heart Failure
Arrhythmias, Cardiac, Atrial Fibrillation
Activation Timing and Atrial Fibrillation
This is a single center, non-randomized, unblinded study of patients who are followed at Essentia Health - St. Mary's Medical Center and who are referred for a clinically indicated diagnostic electrophysiology (EP) study with or…
- Conditions
- Arrhythmias, Cardiac, Atrial Fibrillation, Bundle Branch Block
- Trial name
- AF-Activate (NCT02063191)
- Where
- United States
- Volunteers
- 3 people
- Sponsor
- Essentia Health
Refractory Ventricular Tachycardia
PrOsPective Cohort Study for STereotactic Arhythmia Radioablation (STAR) of Refractory Ventricular Tachycardia
This is a multicenter, interventional study. The study will enroll patients that fulfill the inclusion criteria over a 33-month period.
- Trial name
- POPSTAR (NCT06294782)
- Testing
- STereotactic Arhythmia Radioablation (STAR)
- Where
- Italy
- Volunteers
- 30 people
- Sponsor
- University of Turin, Italy
Defibrillators, Implantable, Myocardial Infarction
Risk of Life-threatening Heart Rhythm Disturbances in Siblings
The purpose of this study is to determine if heredity influences the risk of life-threatening heart rhythms (ventricular tachycardia and ventricular fibrillation) after heart attack (myocardial infarction).
- Conditions
- Defibrillators, Implantable, Myocardial Infarction, Tachycardias, Ventricular
- Trial name
- SIBFIB (NCT00498524)
- Testing
- ICD
- Where
- United States
- Volunteers
- 2,047 people
- Sponsor
- Duke University
Ventricular Outflow Tract Ventricular Arrhythmias, Radio Frequency Catheter Ablation
"Right Ventricular Outflow Tract Posterior Septum Pacing" in Predicting Ventricular Outflow Tract Ventricular Tachycardia Origin
The goal of this clinical trial is to make clear that a new method, right ventricular outflow tract (RVOT) posterior septum pacing, has a greater accuracy in predicting the origin of ventricular outflow tract (VOT) ventricular…
- Trial name
- NCT06360003
- Testing
- Right Ventricular Outflow Tract Posterior Septum Pacing, systemic mapping and ablation
- Where
- China
- Volunteers
- 109 people
- Sponsor
- Second Affiliated Hospital of Wenzhou Medical University
Transcatheter Aortic Valve Implantation, Physiological Pacing
Randomized Study of Physiological vs Right Ventricular Pacing in Patients With Normal Ventricular Function Post TAVI
Single-center randomized trial in patients with pacing indication (AV block) after TAVI (transfemoral aortic valve implantation) and LVEF> 50%, that aims to study the percentage of patients who improve at 12 months in a combined…
- Conditions
- Transcatheter Aortic Valve Implantation, Physiological Pacing, Right Ventricular Pacing, AV Block
- Trial name
- PHYSTAVIII (NCT06197503)
- Testing
- Conduction system pacing, Right ventricular pacing
- Where
- Spain
- Volunteers
- 48 people
- Sponsor
- Hospital Clinic of Barcelona
Arrhythmia, Heart Diseases
Fatty Acid Antiarrhythmia Trial (FAAT)
To determine if the dietary N-3 class of polyunsaturated fatty acids (PUFAs) provided in the diet largely from marine fish oils would prevent fatal ventricular tachycardia (VT) or ventricular fibrillation (VF).
- Conditions
- Arrhythmia, Heart Diseases, Tachycardia, Ventricular, Ventricular Fibrillation
- Trial name
- NCT00004559
- Testing
- dietary polyunsaturated fatty acid
- Sponsor
- National Heart, Lung, and Blood Institute (NHLBI)
Bradyarrhythmia
Mechanical and Electrical Dyssynchrony During His-Bundle Pacing Versus His-Bundle Area Right Ventricular Pacing
The aim of this study is to evaluate mechanical and electrical cardiac dyssynchrony in patients with pacemakers and the right ventricular electrode implanted in His Bundle area.
- Trial name
- NCT04697797
- Testing
- Device Programming
- Where
- Poland
- Volunteers
- 100 people
- Sponsor
- Medical University of Lodz
Heart Failure
Sensing Ventricular Arrhythmias by His Bundle Leads
The purpose of this trial is to determine if implantable cardiac device leads implanted in the His bundle are capable of detecting ventricular arrhythmias.
- Trial name
- NCT03530423
- Where
- United States
- Sponsor
- The Guthrie Clinic
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