Clinical trials: Arrhythmias Ventricular
Scar-related Atrial Tachycardia, Persistent Atrial Fibrillation
A Study Assessing Arrhythmia Mapping With a Globe-Shaped, High-Density, Multi-Electrode Mapping Catheter
The purpose of this study is to assess the performance and safety for the use of the investigational catheter for intracardiac mapping in the atria and ventricles.
- Conditions
- Scar-related Atrial Tachycardia, Persistent Atrial Fibrillation, Paroxysmal Atrial Fibrillation, Ventricular Tachycardia
- Trial name
- COSMOS (NCT05373862)
- Testing
- Globe-Shaped, High-Density, Multi-Electrode Mapping Catheter
- Where
- 4 sites in Belgium, Croatia and 1 more
- Volunteers
- 40 people
- Sponsor
- Biosense Webster, Inc.
Idiopathic Ventricular Fibrillation, Cardiac Arrest, Out-Of-Hospital
MEdical Treatment in Idiopathic Ventricular Fibrillation Patients
A person who has experienced a cardiac arrest with no apparent cause is at risk of having recurrent cardiac arrest. Hence an implantable cardioverter-defibrillator (ICD) is recommended on empirical grounds.
- Trial name
- RIME-IVF (NCT07405229)
- Testing
- Beta-blocker treatment group
- Where
- 2 sites in Denmark
- Volunteers
- 218 people
- Sponsor
- Bo Gregers Winkel
Sinus Bradycardia, Sinus Node Disease
Real Life Automatic Atrial Capture Device Control
The main objective of this study is to verify the effectiveness of the new ACAP ® Confirm algorithm in the automatic management of atrial capture.
- Conditions
- Sinus Bradycardia, Sinus Node Disease, Atrio-ventricular Block, Heart Failure
- Trial name
- NCT02400983
- Testing
- Pacemaker, ICD
- Volunteers
- 318 people
- Sponsor
- Maria Vittoria Hospital
Ventricular Tachycardia
Preventive aBlation of vEntricular tachycaRdia in Patients With myocardiaL INfarction
The BERLIN VT study is designed to evaluate the impact of prophylactic ventricular tachycardia (VT) ablation on all-cause mortality and unplanned hospital admission for congestive heart failure or symptomatic ventricular…
- Trial name
- BERLIN VT (NCT02501005)
- Testing
- VT ablation
- Where
- 5 sites in Germany
- Volunteers
- 163 people
- Sponsor
- Biotronik SE & Co. KG
COVID-19, Myocarditis
Support for the Resumption of Training of High-level Athletes Post-epidemic COVID-19
As of March 2020, COVID-19 has become a global pandemic, halting athletic competition worldwide. Reports from China show a high prevalence of cardiac involvement in patients with severe SARS-CoV-2 infection.
- Trial name
- ASCCOVID19 (NCT04936503)
- Testing
- Resting electrocardiogram, Stress test, Cardiac echocardiography
- Where
- 21 sites in France
- Volunteers
- 984 people, healthy volunteers welcome
- Sponsor
- University Hospital, Bordeaux
Ventricular Tachycardia, Monomorphic, Ventricular Tachycardia, Sustained
Stereotactic Radiosurgery as Second-line Therapy for Ventricular Tachycardia
The aim of the study is to compare the efficacy and safety of treating recurrent sustained Ventricular Tachycardia (sVT) after prior Catheter Ablation (CA) in patients with Implanted Cardioverter-Defibrillator (ICD) between re-do…
- Conditions
- Ventricular Tachycardia, Monomorphic, Ventricular Tachycardia, Sustained, Ventricular Tachycardia (VT), Ventricular Tachycardia (V-Tach)
- Trial name
- STAR-4VT (NCT07017855)
- Testing
- Stereotactic Arrhythmia Radioablation (STAR), Catheter Ablation
- Where
- Poland
- Volunteers
- 150 people
- Sponsor
- Medical University of Silesia
Premature Ventricular Complex
Electrocardiographic and Cardiac Magnetic Resonance Predictors of Ventricular Arrhythmias in Cardiomyopathic Patients
This study aims to assess ECG changes for predicting ventricular arrhythmia in cardiomyopathic patients
- Trial name
- NCT05078125
- Testing
- Holter monitoring
- Volunteers
- 79 people
- Sponsor
- Assiut University
Arrhythmia
A Multi-centre Study Comparing the Effects of AZD2927 and Placebo on the Electrical Activity in the Heart in Patients
Medical Products Agency
- Trial name
- NCT01396226
- Testing
- AZD2927
- Where
- 5 sites in Norway, Sweden
- Volunteers
- 20 people
- Sponsor
- AstraZeneca
Post COVID-19, Ventricular Repolarization
Changes in Electrocardiographic (ECG) Ventricular Repolarization and Transthoracic Impedance Cardiography (ICG) Parameters in Patients with COVID-19 and After the Disease: Persistence and Prognostic Significance of These Changes
The aim of this study is to determine the relationship between changes in resting electrocardiography (ECG) ventricular repolarization parameters, transthoracic impedance cardiography (ICG) parameters, and COVID-19, to assess the…
- Conditions
- Post COVID-19, Ventricular Repolarization, Arrhythmias, Impedance Cradiography
- Trial name
- NCT06674278
- Volunteers
- 215 people
- Sponsor
- Lithuanian University of Health Sciences
Cardiac Event, Sudden Cardiac Death
To Determine Optimal Time for Delivering Electrical Shocks to Cardiac Arrest Patients
In this study, we are comparing the difference in outcomes between patients who were given shocks to the heart, during the upstroke of cardiopulmonary resuscitation (CPR) and before CPR is started.
- Conditions
- Cardiac Event, Sudden Cardiac Death, Death, Ventricular Fibrillation
- Trial name
- NCT01665755
- Testing
- Upstroke Compression Defibrillation, Precompression Defibrillation
- Where
- Singapore
- Volunteers
- 180 people
- Sponsor
- Singapore General Hospital
Ventricular Tachycardia (VT), Premature Ventricular Contraction (PVC)
Computational Cardiac Imaging Analysis to Guide Ventricular Tachycardia Ablation Procedures (AI-VT)
The purpose of this study is to evaluate the clinical outcomes (clinical efficacy and safety) of using supplemental non-invasive computational ECG and cardiac imaging analysis tools to help guide ablation of ventricular…
- Conditions
- Ventricular Tachycardia (VT), Premature Ventricular Contraction (PVC), Ventricular Fibrillation
- Trial name
- AI-VT (NCT06964152)
- Testing
- Computational electrocardiography and cardiac computed tomography mapping
- Where
- United States
- Volunteers
- 250 people
- Sponsor
- University of California, San Diego
Ventricular Arrhythmias and Cardiac Arrest
Epicardial Ablation in Brugada Syndrome to Prevent Sudden Death
A total of 150 patients will be randomized to perform catheter ablation or not in a 2:1 fashion in selected patients with Brugada-related symptoms (Ablation+ICD arm 105 patients vs ICD only 45 patients).
- Trial name
- NCT03294278
- Testing
- ablation plus ICD
- Where
- Italy
- Volunteers
- 150 people
- Sponsor
- IRCCS Policlinico S. Donato
Cardiac Pacing, Pacing-Induced Cardiomyopathy
LVSP vs RVP in Patients With AV Conduction Disorders
Rationale: Permanent cardiac pacing is the only available therapy in patients with atrioventricular (AV) conduction disorders and can be life-saving.
- Conditions
- Cardiac Pacing, Pacing-Induced Cardiomyopathy, Conduction System Pacing, Left Ventricular Septal Pacing
- Trial name
- LEAP (NCT04595487)
- Testing
- Left ventricular septal pacing, Right ventricular pacing
- Where
- 13 sites in Belgium, Czechia and 5 more
- Volunteers
- 470 people
- Sponsor
- Maastricht University
Heart Arrest, Ventricular Fibrillation
Observational and Diagnostical Study on Transient Allostatic Responses of Thyroid Function After Cardiopulmonary Resuscitation
Time-limited adaptive responses of thyroid function are common in the critically ill. About 70% of all patients treated on intensive care units develop a so-called non-thyroidal illness syndrome (NTIS) or TACITUS (thyroid…
- Conditions
- Heart Arrest, Ventricular Fibrillation, Ventricular Flutter, Ventricular Tachycardia
- Trial name
- Thyro-CPR (NCT04392258)
- Testing
- TSH determination, FT4 determination, FT3 determination
- Where
- Germany
- Volunteers
- 200 people
- Sponsor
- Ruhr University of Bochum
Death, Sudden, Cardiac, Ventricular Fibrillation
DISCOVERY: Diagnostic Data and Genetic Polymorphisms in ICD Patients.
To prospectively evaluate if the analysis of genetic polymorphisms can be used to identify patients at risk of ventricular tachycardia.
- Conditions
- Death, Sudden, Cardiac, Ventricular Fibrillation, Tachycardia, Atrial Fibrillation
- Trial name
- DISCOVERY (NCT00478933)
- Testing
- Defibrillator, Dual Chamber ; Implantable, Blood sampling
- Volunteers
- 1,223 people
- Sponsor
- Medtronic Cardiac Rhythm and Heart Failure
Atrial Fibrillation
Propagation ANalysis for Arrhythmogenic Conduction Elimination to Prevent Atrial Flutter and Fibrillation (PANACEA-AF)
The purpose of this study is to perform ultra-high density mapping of the left atrium (a chamber of the heart) using the the Rhythmia Mapping System and to determine whether additional ablation in areas of wavefront…
- Trial name
- PANACEA-AF (NCT03737838)
- Testing
- Atrial fibrillation ablation
- Where
- United States
- Volunteers
- 29 people
- Sponsor
- University of Chicago
Ventricular Tachycardia
Low Energy Therapy to Convert Ventricular Tachycardias
The LEVER study is a prospective, unblinded, non-randomized, first in human feasibility study that will assess and characterize early safety and effectiveness of low energy therapies in converting monomorphic ventricular…
- Trial name
- LEVER (NCT02891863)
- Testing
- LEVER Acute Study System
- Where
- Australia
- Volunteers
- 9 people
- Sponsor
- Boston Scientific Corporation
Ventricular Tachycardia
Outcomes of Functional Substrate Mapping of Ventricular Tachycardia
The goal of this registry database is to demonstrate the safety and effectiveness of functional ventricular tachycardia (VT) ablation using SENSE protocol in patients with ischaemic VT.
- Trial name
- VTFM (NCT05708131)
- Where
- 8 sites in United States, Greece and 2 more
- Volunteers
- 70 people
- Sponsor
- Mid and South Essex NHS Foundation Trust
ISCHEMIC CARDIOMYOPATHY
Efficacy of EVP 1001-1 (SeeMore) in the Assessment of Myocardial Viability in Patients With Cardiovascular Disease
The investigator hopes to introduce a novel MRI contrast agent with SeeMore ™ that directly defines viable myocardium. Identifying viable myocardium non-invasively using cardiac MRI is still a moving target and a question we plan…
- Trial name
- NCT01989195
- Testing
- 'SEEMORE' - MANGANESE-ENHANCED MRI CONTRAST REAGENT
- Where
- United States
- Volunteers
- 6 people
- Sponsor
- Stanford University
COVID, Arrhythmia
COVIDAR - Arrhythmias in COVID-19
BACKGROUND AND RATIONALE: There is very limited literature available on the arrhythmia occurrence in the context of an infection by the SARS-CoV2 virus.
- Conditions
- COVID, Arrhythmia, Torsades de Pointe Caused by Drug, Qt Interval, Variation in
- Trial name
- COVIDAR (NCT04437901)
- Where
- 5 sites in Belgium, Italy and 3 more
- Volunteers
- 10,000 people
- Sponsor
- Hospital Clinic of Barcelona
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