Clinical trials: Arrhythmias Ventricular
Atrial Fibrillation
Study of the Effect of Cardioversion on Cardiac Volume in Patients With Persistent Atrial Fibrillation
The main objectives in this study were to examine the cardiac structural and functional changes in patients with persistent and permanent AF, with the aim of improving our understanding of the underlying pathophysiological…
- Trial name
- NCT00209911
- Testing
- cardioversion
- Where
- Denmark
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Hvidovre University Hospital
HIS Bundle Pacing, Atrial Fibrillation
Ablate and Pace HIS Study
Atrial fibrillation (AF) is the most common sustained cardiac arrhythmia, and estimates suggest its prevalence is increasing. Despite the advances in AF ablation strategies, the outcome of ablation procedures in persistent AF is…
- Trial name
- NCT06152406
- Testing
- Ablation and Pacemaker Implantation
- Where
- United Kingdom
- Volunteers
- 100 people
- Sponsor
- University Hospitals, Leicester
Atrial Fibrillation New Onset, Hemorrhage
Randomized Double Blind Control Trial on Effects of Ranolazine on New Onset Atrial Fibrillation
The aim of this study is to evaluate the prophylactic effects of Ranolazine on new onset atrial fibrillation in post-operative coronary artery bypass graft and valve surgery patient population at Staten Island University hospital.
- Conditions
- Atrial Fibrillation New Onset, Hemorrhage, Prolonged QTc Interval, Ventricular Tachycardia
- Trial name
- NCT01590979
- Testing
- Ranolazine
- Where
- United States
- Volunteers
- 54 people
- Sponsor
- Northwell Health
Cardiovascular Diseases, Heart Diseases
Predictors of Perioperative Cardiac Morbidity
To determine the predictors of perioperative cardiac morbidity and mortality in patients at high risk who underwent major noncardiac surgery with general anesthesia.
- Conditions
- Cardiovascular Diseases, Heart Diseases, Myocardial Ischemia, Myocardial Infarction
- Trial name
- NCT00005197
- Sponsor
- National Heart, Lung, and Blood Institute (NHLBI)
Ventricular Fibrillation, Ventricular Tachycardia
Further Acute Research of a Subcutaneous Implantable Defibrillator (S-ICD) System
The purpose is to further evaluate the operation, safety, and feasibility of a subcutaneous implantable defibrillator (S-ICD) system in patients who require an implantable cardioverter defibrillator (ICD)for treating ventricular…
- Trial name
- NCT00399217
- Testing
- Subcutaneous Implantable Defibrillator (S-ICD) system, ICD
- Where
- United Kingdom
- Volunteers
- 55 people
- Sponsor
- Boston Scientific Corporation
Tricuspid Valve Insufficiency, Sick Sinus Syndrome
Left Ventricular Pacing to Prevent Iatrogenic TR Pilot Study
Background and Aims Pacemaker implantation for treating bradyarrhythmias typically involves placing a pacing lead through the tricuspid valve (TV) into the right ventricular (RV) apex.
- Trial name
- NCT02314897
- Testing
- LV pacing, RV pacing
- Where
- Singapore
- Volunteers
- 20 people
- Sponsor
- National University Hospital, Singapore
Paroxysmal Supraventricular Tachycardia (PSVT)
The PSVT Place Registry.Paroxysmal Supraventricular Tachycardia (PSVT) Registry.
Paroxysmal supraventricular tachycardia (PSVT) is a sporadic, sudden, and recurring tachycardia that is caused by an altered electrical conductivity in the heart.
- Trial name
- NCT03353610
- Where
- United States
- Volunteers
- 354 people
- Sponsor
- Milestone Pharmaceuticals Inc.
Death, Sudden, Cardiac, Out-Of-Hospital Cardiac Arrest
Pre-hospital ECMO in Advanced Resuscitation in Patients With Refractory Cardiac Arrest. ( SUB30 )
To establish whether a pre-hospital advanced physician/ paramedic cardiac arrest team that is ECMO capable can establish ECMO flow within 30 minutes of collapse.
- Conditions
- Death, Sudden, Cardiac, Out-Of-Hospital Cardiac Arrest, Ventricular Fibrillation, Cardiopulmonary Arrest With Successful Resuscitation
- Trial name
- SUB30 (NCT03700125)
- Testing
- ECMO resuscitation
- Where
- 2 sites in United Kingdom
- Volunteers
- 5 people
- Sponsor
- Barts & The London NHS Trust
Hypertrophic Cardiomyopathy
A Prospective Incident Study of Arrhythmias in Hypertrophic Cardiomyopathy
The purpose of this research study is to understand more about various heart rhythms (electrical problems) in persons with hypertrophic cardiomyopathy with and without sleep apnea.
- Trial name
- NCT04112290
- Where
- United States
- Volunteers
- 260 people
- Sponsor
- Mayo Clinic
Ventricular Tachycardia
A Study of Early Robotic Ablation by Substrate Elimination of Ventricular Tachycardia
Ventricular tachycardia (VT) is an abnormal rapid heartbeat which occurs after a heart attack and can cause sudden death. Patients at risk of this rhythm disturbance usually receive an implantable cardioverter defibrillator (ICD)…
- Trial name
- ERASE-VT (NCT01182389)
- Testing
- Robotic VT Ablation, Conventional Therapy
- Where
- 3 sites in United Kingdom
- Volunteers
- 51 people, healthy volunteers welcome
- Sponsor
- Imperial College London
Atrial Fibrillation, Left Ventricular Diastolic Dysfunction
Characterizing Patients With POAF in Relation to Cardiac Surgery by wavECG and TTE
Post-operative atrial fibrillation (POAF) is frequently observed after open-heart surgery. Despite numerous attempts to predict POAF, it remains a challenge to correctly identify the patients at risk.
- Trial name
- NCT03962166
- Where
- Denmark
- Volunteers
- 353 people
- Sponsor
- Helena DOMINGUEZ
Tachycardia, Ventricular, Heart Failure, Congestive
OMNI Study--Assessing Therapies in Medtronic Pacemaker, Defibrillator, and Cardiac Resynchronization Therapy Devices.
The purpose of the OMNI study is to characterize therapy and diagnostic utilization in study participants implanted with study devices and to describe Implantable Cardioverter Defibrillator(ICD)therapy utilization for life…
- Conditions
- Tachycardia, Ventricular, Heart Failure, Congestive, Ventricular Fibrillation, Ventricular Dysfunction
- Trial name
- OMNI (NCT00277524)
- Where
- 113 sites in United States
- Volunteers
- 3,032 people
- Sponsor
- Medtronic Cardiac Rhythm and Heart Failure
Myocarditis, Ventricular Arrythmia
GEAM Study Aims At Assessing the Role of Genetic Testing in Patients with Arrhythmic Myocarditis.
This study aims to answer multiple unsolved questions in the field of arrhythmic myocarditis. Improving the diagnostic work-up. While endomyocardial biopsy (EMB) and cardiac magnetic resonance (CMR) constitute the gold standard…
- Trial name
- GEAM (NCT06889662)
- Where
- Italy
- Volunteers
- 262 people, healthy volunteers welcome
- Sponsor
- Scientific Institute San Raffaele
Atrial Fibrillation, Heart Failure, Systolic
Atrial FIbrillation Treatment With Cryoballoon in Heart failurE (AFICHE)
In this study 404 patients with heart failure and an ejection fraction of 0.40 or less, with paroxysmal atrial fibrillation, will be randomly assigned to standard treatment or standard treatment plus a session of cryoballoon…
- Trial name
- AFICHE (NCT03573869)
- Testing
- Cryoballoon ablation
- Where
- Greece
- Volunteers
- 404 people
- Sponsor
- G.Gennimatas General Hospital
Ventricular Arrhythmias
Evaluation of Electrocardiographic Measurements by High Density Electrode ECG
Cardiac electrical activity is detected on the body surface with conventional electrocardiography involving 12 leads (ECG 12). A limitation of the current ECG technique is that recordings are obtained from only 6 independent…
- Trial name
- ECG-HD (NCT04921501)
- Testing
- HD ECG, Conventional 12-lead ECG
- Where
- 11 sites in France, Monaco
- Volunteers
- 1,800 people
- Sponsor
- University Hospital, Bordeaux
Non-ischemic Cardiomyopathy, Cardiomyopathies
Cardiovascular Multimodality Imaging Study
Determining the etiology of cardiomyopathy is of high clinical importance for optimal treatment strategy and prediction of prognosis.
- Conditions
- Non-ischemic Cardiomyopathy, Cardiomyopathies, Hypertrophic Cardiomyopathy, Right Ventricular Arrhythmogenic Cardiomyopathy
- Trial name
- NCT06610019
- Where
- United States
- Volunteers
- 10,000 people
- Sponsor
- Montefiore Medical Center
Bradycardia, Heart Failure
LEft Bundle branchArea Pacing to Avoid Pacing-induced CARdiomyopathy
LEAP-CAR will evaluate the benefit of left bundle branch area pacing (LBBAP), comparing to conventional right ventricular pacing (RVP), in preventing pacing-induced cardiomyopathy (PICM) in patients undergoing pacemaker implant…
- Conditions
- Bradycardia, Heart Failure, Pacemaker-Induced Cardiomyopathy, Conduction Block, Atrioventricular
- Trial name
- LEAP-CAR (NCT05910866)
- Testing
- Left bundle branch area pacing (LBBAP), Right ventricular pacing (RVP)
- Where
- Italy
- Volunteers
- 130 people
- Sponsor
- Azienda Ospedaliero Universitaria Maggiore della Carita
Ventricular Fibrillation, Ventricular Tachycardia
Remote Follow-up of Patients Receiving Implantable Cardioverter Defibrillator for Prophylactic Therapy
The completed MADIT II study has shown that implantation of a cardioverter-defibrillator (ICD) in patients with a reduced left ventricular ejection fraction and a prior myocardial infarction reduces death from any cause.
- Trial name
- REFORM (NCT00401466)
- Testing
- Implantable Cardioverter Defibrillator
- Where
- 5 sites in Czechia, Germany
- Volunteers
- 155 people
- Sponsor
- Biotronik SE & Co. KG
Ventricular Tachycardia, Atrial Fibrillation
AVAI: Atrial Ventricular Arrythmia Incidence
The purpose of this observational study is to collect data regarding the population of patients implanted with St. Jude Medical ICD.
- Trial name
- AVAI (NCT00832975)
- Where
- 2 sites in Spain
- Volunteers
- 157 people
- Sponsor
- Abbott Medical Devices
Cardiovascular Diseases, Coronary Artery Disease
AI-Powered Electrocardiography for Diagnosis and Prognostic Prediction in Cardiovascular Disease (AI-CVD): Multicenter Retrospective Study
This multicenter retrospective study aims to develop, validate, and clinically apply an artificial intelligence (AI)-powered electrocardiography (ECG) algorithm for the diagnosis and prognostic prediction of cardiovascular…
- Conditions
- Cardiovascular Diseases, Coronary Artery Disease, Heart Failure, Atrial Fibrillation (AF)
- Trial name
- AI-CVD (NCT07856472)
- Testing
- Retrospective ECG Data Analysis
- Where
- South Korea
- Volunteers
- 10,000 people
- Sponsor
- Inha University Hospital
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