Clinical trials: Arrhythmias Ventricular
Appropriate and Inappropriate Shock Therapy With ICD, Arrhythmias Detection
Arrhythmias Detection in a Real World Population
The study is a prospective multicenter registry. Consecutive patients with indications of implant / replacement or upgrade of implantable cardioverter defibrillator (ICD) will be enrolled.
- Trial name
- RHYTHM DETECT (NCT02275637)
- Testing
- implantable cardioverter defibrillator
- Where
- 12 sites in Italy
- Volunteers
- 10,000 people
- Sponsor
- Fondazione IRCCS Policlinico San Matteo di Pavia
Refractory Ventricular Tachycardia
STereotactic RadioAblation by Multimodal Imaging for VT (STRA-MI-VT)
Study of multimodal-imaging guided stereotactic body radiotherapy (SBRT) for ventricular tachycardia (VT) ablation.
- Trial name
- STRA-MI-VT (NCT04066517)
- Testing
- SBRT
- Where
- 2 sites in Italy
- Volunteers
- 20 people
- Sponsor
- Centro Cardiologico Monzino
Ventricular Tachycardia, Ventricular Fibrillation
MAVRIC VR ICD Registry
The purpose of this registry is to collect information on the health status of patients receiving Marquis/Maximo VR Implantable Cardiac Defibrillators (ICDs), how the devices are being programmed and how this correlates to…
- Trial name
- NCT00270933
- Testing
- Registry
- Where
- 91 sites in United States, Canada
- Volunteers
- 742 people
- Sponsor
- Medtronic Cardiac Rhythm and Heart Failure
Ventricular Tachycardia, Monomorphic, Ventricular Tachycardia (V-Tach)
Imaging and Treatment Planning for Cardiac Radioablation
Cardiac radioablation is a new treatment for ventricular tachycardia (VT), which uses beams of radiation to treat heart scar that causes VT.
- Conditions
- Ventricular Tachycardia, Monomorphic, Ventricular Tachycardia (V-Tach), Ischemia, Myocardial
- Trial name
- ITPCR (NCT06938074)
- Testing
- CT and MRI
- Where
- Canada
- Volunteers
- 15 people
- Sponsor
- Stewart Gaede
Ventricular Tachyarrhythmias
Ablation of Ventricular Fibrillation by Accurate Targeting of Arrhythmogenic Regions (AVATAR)
This study will test the hypothesis that many human heart rhythm disorders are caused by small localized sources, where brief ablation may successfully eliminate the heart rhythm disorder.
- Trial name
- AVATAR (NCT01492764)
- Where
- 2 sites in United States
- Volunteers
- 2 people
- Sponsor
- University of California, San Diego
Ventricular Fibrillation
Canadian Registry of ICD Implant Testing Procedures
To document practices in Canadian ICD implant centres around defibrillation therapy efficacy testing.
- Trial name
- NCT00848341
- Testing
- GUIDANT ICD SYSTEM
- Volunteers
- 261 people
- Sponsor
- Guidant Corporation
Heart Failure With Reduced Ejection Fraction
Improving CRT Outcome With Non-Invasive Cardiac Mapping
The ICONIC-M study is a multicenter randomized controlled study to assess patient response to CRT comparing ECGI map guided left ventricular lead placement with empirical lead placement.
- Trial name
- ICONIC-M (NCT05564793)
- Testing
- Pre-implantation planning, Post-implantation assessment
- Where
- 11 sites in Netherlands, Portugal and 2 more
- Volunteers
- 330 people
- Sponsor
- EP Solutions SA
Sick Sinus Syndrome
Right Ventricle (RV) Markers of Future Pacing Induced Ventricular Dysfunction - Pilot
This is a pilot study into the effects on heart function when pacing the right ventricle (RV). This study aims to enrol a population who are clinically indicated to receive a pacemaker.
- Trial name
- NCT02198781
- Where
- United Kingdom
- Volunteers
- 3 people
- Sponsor
- Mid and South Essex NHS Foundation Trust
Arrhythmia
Study Evaluating GAP-486 on Heart Rhythm in Patients With Coronary Artery Disease
The purpose of this study is to learn the effects of a test drug on heart rhythms, which may become life-threatening if left untreated, and to provide data to see if the drug is well tolerated and safe.
- Trial name
- NCT00137332
- Testing
- GAP-486 (ZP-123), 0.9% Sodium Chloride, USP
- Where
- 33 sites in United States, Canada
- Volunteers
- 90 people
- Sponsor
- Wyeth is now a wholly owned subsidiary of Pfizer
Rapid Arrhythmia, Atrial Fibrillation (AF)
Safety and Efficacy Study of the First Domestically Produced FireMagic™ PreciSense™ 3D Microelectrode Ablation Catheter Therapy for Rapid Arrhythmia With Tissue Temperature Measurement Function
This project aims to evaluate the safety, efficacy, and cost-effectiveness of using FireMagic™ PreciSense™ 3D Microelectrode Ablation Catheter to treat rapid arrhythmias.
- Conditions
- Rapid Arrhythmia, Atrial Fibrillation (AF), Paroxysmal Supraventricular Tachycardia (PSVT)
- Trial name
- NCT07032948
- Testing
- FireMagic™ PreciSense™ 3D Microelectrode Ablation Catheter、EasyStars™ High Density Mapping Catheter、Columbus™ 3D EP Navigation System
- Volunteers
- 300 people
- Sponsor
- Shanghai MicroPort EP MedTech Co., Ltd.
Ventricular Tachycardia (VT)
VT ART Consortium: Radioablation for Ventricular Tachycardia
The overall objective of the study is to evaluate the efficacy and safety of stereotactic radiation therapy in the non invasive ablation of ventricular tachycardia refractory to any other type treatment.
- Trial name
- VT-ART-P (NCT06922214)
- Testing
- Stereotactic Body Radiation Therapy (SBRT)
- Where
- Italy
- Volunteers
- 52 people
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Electrical Storm, Stellate Ganglion Block
Percutaneous Blockade of the Stellate Ganglion in Electrical Storm
There is no randomized clinical study in the literature that evaluated the efficacy and safety of the stellate ganglion infiltration procedure in patients with electrical storm.
- Conditions
- Electrical Storm, Stellate Ganglion Block, Ventricular Arrhythmia
- Trial name
- NCT07211347
- Testing
- Stellate Ganglion Block
- Where
- Brazil
- Volunteers
- 64 people
- Sponsor
- University of Sao Paulo General Hospital
Ventricular Arrhythmias, Atrial Fibrillation
Ventricular Arrhythmias After Pulmonary Vein Isolation
The investigators study aimed to observe the occurrence of new premature ventricular complexes and other ventricular arrhythmias after pulmonary vein isolation.
- Trial name
- NCT02699255
- Where
- Germany
- Volunteers
- 111 people
- Sponsor
- Universitätsklinikum Hamburg-Eppendorf
Ventricular Fibrillation, Ventricular Tachycardia
Evaluation of the iD-SystemTM, One-Handed Disposable Internal Defibrillation System.
The main aim is to evaluate the safety and efficacy of the iD-System™, One-handed Disposable Internal Defibrillation System The device is made for manual defibrillation during intra-thoracic procedure, by transferring a shock…
- Trial name
- iD-System (NCT04011631)
- Testing
- Internal defibrillation during cardiac surgery, using the iD-system
- Where
- Belgium
- Volunteers
- 100 people
- Sponsor
- SMART Clinical Products BV
Aortic Stenosis, Atrial Fibrillation New Onset
Long Term Evaluation of Cardiac Arrhythmias After Transcatheter Aortic Valve Implantation -The LOCATE Registry
The purpose of the Long term Evaluation of Cardiac Arrhythmias after Transcatheter Aortic Valve Implantation (LOCATE) Registry is to perform long-term ambulatory monitoring of patients with severe aortic stenosis who undergo…
- Conditions
- Aortic Stenosis, Atrial Fibrillation New Onset, Heart Block
- Trial name
- NCT06055751
- Testing
- TAVR Procedure and implantation of Boston Scientific Loop Recorder (LUX-Dx PMA# K193473)
- Where
- 2 sites in United States
- Volunteers
- 50 people
- Sponsor
- Kansas City Heart Rhythm Research Foundation
Ventricular Arrythmia, Lead
Safety and Electrical Performance Evaluation of INVICTA Leads Models Equipped With DF4 Connector
The primary objective of this study is to assess the safety and key electrical performance of the INVICTA leads equipped with DF4 connector: ACTIVE fixation type models (single and dual coil: INVICTA 1CR, INVICTA 2CR) and PASSIVE…
- Conditions
- Ventricular Arrythmia, Lead, ICD, Heart Failure
- Trial name
- FRIENDS (NCT03766919)
- Testing
- Implant of the INVICTA lead
- Where
- 10 sites in France, Italy and 2 more
- Volunteers
- 33 people
- Sponsor
- MicroPort CRM
Ventricular Premature Complexes, Catheter Ablation
MANual vs. automatIC Local Activation Time Annotation for Guiding Premature Ventricular Complex Ablation
Current navigation systems incorporate algorithms for automatic identification of local activation time (LAT). However, data about their utility and accuracy in premature ventricular complex (PVC) ablation procedures are scarce.
- Trial name
- MANIaC-PVC (NCT03340922)
- Testing
- Automatic annotation of LAT (WF-method), Manual annotation of LAT (M-method)
- Where
- Spain
- Volunteers
- 100 people
- Sponsor
- Centro Medico Teknon
Sudden Cardiac Death, Heart Failure
Cardiac Rehab Retrospective Review (CR3)
All patients enrolled in the Austrian LifeVest Registry will be retrospectively screened for successfully completed ambulatory or stationary rehabilitation program.
- Conditions
- Sudden Cardiac Death, Heart Failure, Ventricular Arrythmia, Ventricular Tachycardia
- Trial name
- CR3 (NCT04675957)
- Testing
- cardiac rehabilitation
- Where
- Austria
- Volunteers
- 55 people
- Sponsor
- Medical University of Graz
Conduction Defect
Subcostal Temporary Extravascular Pacing V Study
The STEP V Study is a prospective, multicenter, acute (in-hospital), single-arm feasibility study. The objective of the study is to evaluate the early safety and performance of the latest AtaCor EV Temporary Pacing Lead System…
- Trial name
- STEP V (NCT05633394)
- Testing
- AtaCor StealthTrac Lead
- Where
- Paraguay
- Volunteers
- 29 people
- Sponsor
- AtaCor Medical, Inc.
Ventricular Tachycardia, Ventricular Fibrillation
Septal Positioning of Ventricular Implanted Cardioverter Defibrillator (ICD) Leads
This clinical trial is a multi center, prospective, randomized, parallel study designed to compare septal to apical ICD lead placement.
- Trial name
- SPICE (NCT00745745)
- Testing
- Device Implantation
- Where
- 21 sites in Germany, Greece
- Volunteers
- 299 people
- Sponsor
- Abbott Medical Devices
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