Clinical trials: Arrhythmias Ventricular
Premature Ventricular Contraction, Ventricular Tachycardia
Ventricular Arrhythmia Ablation With the Use of Non-Invasive ECG Imaging Technology
Researchers are trying to determine if the use of software called VIVO, made by Catheter Precision, Inc. can shorten the length of time it takes to perform an ablation procedure for either premature ventricular contractions…
- Trial name
- NCT04219501
- Testing
- VIVO
- Where
- United States
- Sponsor
- Mayo Clinic
Ventricular Tachycardia
Stereotactic Management of Arrhythmia - Radiosurgery in Treatment of Ventricular Tachycardia
Prospective single-arm study investigating the safety of non-invasive cardiac radiosurgery for the treatment of ventricular tachycardia (VT).
- Trial name
- SMART-VT (NCT04642963)
- Testing
- Cardiac Radiosurgery
- Where
- 2 sites in Poland
- Volunteers
- 11 people
- Sponsor
- Maria Sklodowska-Curie National Research Institute of Oncology
Ventricular Tachycardia
Evaluation of the DuoVT PFA System for Ventricular Tachycardia
This study is a prospective, non-randomized, single-arm, multicenter study to evaluate the safety and effectiveness of the DuoVT Pulsed Field Ablation (PFA) System.
- Trial name
- EXACT-VT (NCT07706712)
- Testing
- Ablation procedure with DuoVT PFA system
- Where
- 5 sites in Croatia, Czechia and 2 more
- Volunteers
- 50 people
- Sponsor
- Abbott Medical Devices
Ischemic Cardiomyopathy, Nonischemic Cardiomyopathy
Ranolazine Implantable Cardioverter-Defibrillator Trial
The purpose of the study is to see how effective a drug called ranolazine is in reducing the risk of ventricular arrhythmia and death in people with implantable cardioverter-defibrillators (ICDs).
- Conditions
- Ischemic Cardiomyopathy, Nonischemic Cardiomyopathy, Heart Failure
- Trial name
- RAID (NCT01215253)
- Testing
- Ranolazine
- Where
- 90 sites in United States, Canada
- Volunteers
- 1,012 people
- Sponsor
- University of Rochester
Coronary Artery Disease, Acute Myocardial Infarction
A Danish ICD-study in Patients with Coronary Artery Disease Resuscitated from Ventricular Fibrillation
DanICD is a randomized, controlled study to with the aim to assess whether there is a benefit of ICD-implantation in patients with coronary artery disease (including acute myocardial infarction), who survive cardiac arrest due to…
- Conditions
- Coronary Artery Disease, Acute Myocardial Infarction, Ventricular Fibrillation, Ventricular Tachycardia, Sustained
- Trial name
- DanICD (NCT04576130)
- Testing
- Implantable cardioverter defibrillator
- Where
- Denmark
- Volunteers
- 1,200 people
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Arrhythmia, Cardiovascular Diseases
Multicenter Unsustained Tachycardia Trial (MUSTT)
To determine the value of electrophysiologic (EP)-guided antiarrhythmic therapy in coronary heart disease patients at increased risk for sudden death. The study included a controlled clinical trial and a registry.
- Conditions
- Arrhythmia, Cardiovascular Diseases, Coronary Disease, Death, Sudden, Cardiac
- Trial name
- NCT00000480
- Testing
- electrophysiology, anti-arrhythmia agents, defibrillators, implantable
- Sponsor
- National Heart, Lung, and Blood Institute (NHLBI)
Persistent Atrial Fibrillation, Congestive Heart Failure Due to Left Ventricular Systolic Dysfunction
Atrial Fibrillation Ablation Compared to Rate Control Strategy in Patients With Impaired Left Ventricular Function
Atrial fibrillation (AF) and congestive heart failure (CHF) are two epidemics that share several physiopathological links. CHF patients present a significantly increased risk of developing AF and the related detrimental…
- Trial name
- AFARC-LVF (NCT02509754)
- Testing
- Atrial fibrillation catheter ablation, Rate control
- Volunteers
- 180 people
- Sponsor
- University of Turin, Italy
Sudden Death
The Significance of Arrhythmias in Athletes
Athletes with complex ventricular arrhythmias are potentially at risk of sudden death. The aim of the study is to investigate the relevance of ventricular tachyarrhythmias induced by an exercise test in a retrospectively…
- Trial name
- Athlete (NCT00469794)
- Testing
- stress test
- Where
- Israel
- Volunteers
- 300 people
- Sponsor
- Assaf-Harofeh Medical Center
Atrioventricular Conduction Block
Micra Atrial TRacking Using A Ventricular AccELerometer 2
The purpose of the Micra Atrial TRacking Using A Ventricular AccELerometer 2 (MARVEL 2) study is to demonstrate safe and effective operation of the MARVEL 2 features for providing AV synchronous pacing in patients with normal…
- Trial name
- MARVEL2 (NCT03752151)
- Testing
- MARVEL 2 Algorithm Monitor Mode then Adaptive Mode
- Where
- 12 sites in United States, Austria and 6 more
- Volunteers
- 77 people
- Sponsor
- Medtronic Cardiac Rhythm and Heart Failure
Brugada Syndrome, Cardiac Arrest
Feasibility of Improving Risk Stratification in Brugada Syndrome
Feasibility of Improving Risk Stratification in Brugada Syndrome (BrS), retrospective cohort study To study the reproducibility and specificity of V-CoS for activation heterogeneities predisposing to VT/VF in a larger series of…
- Conditions
- Brugada Syndrome, Cardiac Arrest, Athletes Heart, Atrial Fibrillation
- Trial name
- FIRST-BrS (NCT03992677)
- Testing
- No intervention
- Where
- United Kingdom
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Imperial College London
Atrial Fibrillation, Persistent
Effect of taVNS on Heart Rate in Persistent Atrial Fibrillation
The goal of this clinical trial is to investigate the effects of non-invasive transcutaneous auricular vagus nerve stimulation (taVNS) in patients with persistent atrial fibrillation.
- Trial name
- NCT05944575
- Testing
- active taVNS
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Burrell College of Health Sciences
Atrial Fibrillation, Congestive Heart Failure
AVJ Ablation Followed by Resynchronization Therapy in Patients With CHF and AF
The purpose of the study is to determine if the combination of AVJ ablation followed by BiV pacing significantly improves functional status and exercise capacity compared to pharmacologic rate control in patients with chronic AF…
- Trial name
- AVERT-AF (NCT00547794)
- Where
- United States
- Volunteers
- 14 people
- Sponsor
- Abbott Medical Devices
Atrial Flutter With Rapid Ventricular Response
MAGNEsium With meToprolol for Rate Control In Atrial Fibrillation
The purpose of this research study is to find out if the use of magnesium in addition to Metoprolol, a rate controlling medication that you would be offered in the Emergency Department today unrelated to this study, will help…
- Trial name
- MAGNETIC-AF (NCT07632157)
- Testing
- Magnesium Sulfate 2g, Magnesium Sulfate 4g, Saline (0.9% NaCl)
- Where
- United States
- Volunteers
- 196 people
- Sponsor
- Wake Forest University Health Sciences
Ventricular Tachycardia
Power Versus Temperature Controlled Ablation for Treatment of VT
Ventricular Tachycardia (VT) is a life threatening heart rhythm that comes from the bottom chambers of the heart (the ventricles) and is a leading cause of sudden cardiac death.
- Trial name
- DTinVT (NCT06028919)
- Testing
- Temperature controlled DiamondTemp (DT) ablation catheter, Tacticath/Tactiflex (TF) ablation catheter
- Where
- 2 sites in United Kingdom
- Volunteers
- 61 people
- Sponsor
- University Hospitals Coventry and Warwickshire NHS Trust
PKP2 Arrhythmogenic Cardiomyopathy (PKP2-ACM)
A Phase 1, Dose Escalation Trial of RP-A601 in Subjects With PKP2 Variant-Mediated Arrhythmogenic Cardiomyopathy (PKP2-ACM)
This Phase 1 dose escalation trial will assess the safety and preliminary efficacy of a single dose intravenous infusion of RP-A601 in high-risk adult patients with PKP2-ACM.
- Trial name
- NCT05885412
- Testing
- RP-A601
- Where
- 3 sites in United States
- Volunteers
- 9 people
- Sponsor
- Rocket Pharmaceuticals Inc.
Cardiac Arrest, Sudden, Ventricular Tachycardia
Cardiopulmonary Resuscitation Performance of Professional Rescuers With a New Defibrillation Algorithm
In the Paris (France) Medical Emergency system, in the early phase of Out-of-hospital Cardiac Arrest (OHCA), the treatment of a Ventricular Fibrillation (VF) consists of delivering an External Electric Shock (EES) by a rescuer…
- Conditions
- Cardiac Arrest, Sudden, Ventricular Tachycardia, Ventricular Fibrillation, Sudden Cardiac Death
- Trial name
- DEFI-2022 (NCT04691089)
- Where
- France
- Volunteers
- 285 people
- Sponsor
- French Defence Health Service
Cardiovascular Diseases, Death, Sudden, Cardiac
Drug-Induced Sudden Death & Ventricular Arrhythmia
To investigate the relationship between the use of prescription drugs and the occurrence of ventricular arrhythmia and sudden death.
- Conditions
- Cardiovascular Diseases, Death, Sudden, Cardiac, Heart Diseases, Ventricular Arrhythmia
- Trial name
- NCT00102180
- Volunteers
- 31,000,000 people, healthy volunteers welcome
- Sponsor
- University of Pennsylvania
Arrhythmia, Heart Diseases
Antiarrhythmic Effects of N-3 Fatty Acids
To determine the antiarrhythmic effects of dietary N-3 fatty acids in patients with implanted defibrillators.
- Conditions
- Arrhythmia, Heart Diseases, Tachycardia, Ventricular, Ventricular Fibrillation
- Trial name
- NCT00004558
- Testing
- dietary n-3 polyunsaturated fatty acids
- Sponsor
- National Heart, Lung, and Blood Institute (NHLBI)
Tachycardia, Ventricular
CyberHeart's Cardiac Arrhythmia Ablation Treatment: Patients With Refractory Ventricular Tachycardia/Fibrillation
The objective of this clinical investigation is to evaluate: 1. the safety and efficacy of the CyberHeart System, CardioPlan™ Software and Laptop, in treating patients with refractory ventricular tachycardia (VT) using the…
- Trial name
- NCT02661048
- Testing
- CyberHeart System
- Where
- United States
- Volunteers
- 5 people
- Sponsor
- Varian, a Siemens Healthineers Company
Paroxysmal Supraventricular Tachycardia (PSVT)
The PSVT Place Registry.Paroxysmal Supraventricular Tachycardia (PSVT) Registry.
Paroxysmal supraventricular tachycardia (PSVT) is a sporadic, sudden, and recurring tachycardia that is caused by an altered electrical conductivity in the heart.
- Trial name
- NCT03353610
- Where
- United States
- Volunteers
- 354 people
- Sponsor
- Milestone Pharmaceuticals Inc.
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