Clinical trials: Arrhythmias Ventricular
Arrhythmia, Cardiovascular Diseases
Electrophysiologic Study Versus Electrocardiographic Monitoring (ESVEM)
To determine whether electrophysiologic study (EPS) or Holter monitoring (HM) was the better method for selecting effective long-term antiarrhythmic drug therapy in patients with sustained ventricular tachycardia, ventricular…
- Conditions
- Arrhythmia, Cardiovascular Diseases, Death, Sudden, Cardiac, Heart Diseases
- Trial name
- NCT00000518
- Testing
- electrophysiology, electrocardiography, ambulatory, imipramine
- Sponsor
- University of Utah
Ventricular Arrhythmia, Ventricular Tachycardia
Sensing and Defibrillation With a Commercially Available ICD Coupled With a Parasternal Extravascular Lead (SECURE EV) Study
The SECURE EV Study is a prospective, multi-center, single-arm study without concurrent or historical controls. The objectives of the study are 1) to characterize safety of the AtaCor EV-ICD Lead up to 90 days post-implant, and…
- Conditions
- Ventricular Arrhythmia, Ventricular Tachycardia, Ventricular Fibrillation
- Trial name
- SECURE EV (NCT05352776)
- Testing
- AtaCor EV-ICD Lead
- Where
- Paraguay
- Volunteers
- 18 people
- Sponsor
- AtaCor Medical, Inc.
Complete AV Block, Sick Sinus Syndrome
Left Ventricular Pacing to Avoid Cardiac Enlargement Study
In this study, the investigators will examine whether left ventricular pacing is superior to right ventricular apical pacing in preventing deterioration of left ventricular systolic function and cardiac remodeling in patients…
- Trial name
- LVPACE (NCT01302717)
- Testing
- LV pacing, RV pacing
- Where
- 2 sites in South Korea
- Sponsor
- Seoul National University Hospital
Out-Of-Hospital Cardiac Arrest, Ventricular Fibrillation
Real Time Amplitude Spectrum Area to Guide Defibrillation
AMSA trial is a multicenter, randomized, controlled study in out-of-hospital cardiac arrest patients. The purpose of the study is to test the hypothesis that a real time AMSA analysis during CPR may predict the success of…
- Trial name
- AMSA (NCT03237910)
- Testing
- AMSA, Defibrillation, CPR
- Where
- 2 sites in Italy
- Volunteers
- 31 people
- Sponsor
- Mario Negri Institute for Pharmacological Research
Arrhythmias
Study Evaluating GAP-486 in Non-sustained Ventricular Tachycardia
To determine whether the administration of test article will decrease the occurrence of ventricular arrhythmias in patients who have acute coronary syndrome (unstable angina, ST segment elevated myocardial infarction or…
- Trial name
- NCT00124891
- Testing
- Double-blind investigational anti-arrhythmic, GAP-486
- Where
- 75 sites in United States, Brazil and 14 more
- Volunteers
- 500 people
- Sponsor
- Wyeth is now a wholly owned subsidiary of Pfizer
Cardiac Arrhythmia
Novel Cardiac Signal Processing System
This study is designed to collect parallel intracardiac signal data during pre-defined periods of clinical interest from the PURE EP system and the existing signal recording and mapping systems.
- Trial name
- NCT04112433
- Testing
- PURE EP 2
- Where
- 3 sites in United States
- Volunteers
- 104 people
- Sponsor
- BioSig Technologies, Inc.
Arrhythmias, Cardiac, Bradycardia
Analysis of the Efficacy and Stability of a Wearable ECG Monitor
This study aims to analyze the efficacy and safety of wearable electrocardiogram (ECG) monitoring by simultaneously attaching a single-channel patch-type wearable ECG monitoring device (HiCardi+ by Mezoo Co., Ltd.) and a…
- Conditions
- Arrhythmias, Cardiac, Bradycardia, Tachycardia, Atrial Fibrillation
- Trial name
- NCT06546046
- Testing
- ECG monitoring by telemetry device and patch-type ECG monitor at the same time
- Volunteers
- 100 people
- Sponsor
- Mezoo Co., Ltd.
Arrhythmia, Defibrillators, Implantable
Omega 3 Polyunsaturated Fatty Acid Supplements (PUFAs) and Microvolt T Wave Alternans (TWA) in Patients With Ventricular Arrhythmia
This is a hypothesis testing study, the hypothesis being that dietary supplements of n-PUFAs concentrates are anti-arrhythmic in ventricular arrhythmic substrates.
- Trial name
- NCT00507390
- Testing
- n-3 polyunsaturated fatty acids (PUFAs), olive oil
- Where
- United Kingdom
- Sponsor
- University of Dundee
Atrioventricular Block
Impact of Right Ventricular Pacing Determined by Electrocardiography
Typically pacemaker electrode has been attached to the right ventricular apex. This method lead to Non-physiological Ventricular contraction. It has been reported to cause by ventricular dysfunction.
- Trial name
- RVpacing (NCT01922518)
- Testing
- Septal pacing, Apex pacing
- Where
- South Korea
- Volunteers
- 233 people
- Sponsor
- Yong Seog Oh
Heart Block, Sick Sinus Syndrome
Impact of Septal Vs Apical Pacing on Right and Left Ventricular Performance
The study aims to use cardiac MRI scans and analysis techniques to evaluate differences in cardiac function after 12 months of pacing in patients with pacing leads placed in different positions within the right ventricle…
- Conditions
- Heart Block, Sick Sinus Syndrome, Atrioventricular Block, Ventricular Dysfunction
- Trial name
- NCT01798043
- Testing
- Cardiac MRI with pacemaker stimulation, Cardiac MRI with and without pacemaker stimulation
- Where
- Switzerland
- Volunteers
- 29 people
- Sponsor
- Abbott Medical Devices
Ventricular Tachycardia (VT)
Sympathetic Ablation for Ventricular Arrhythmias
Enrolled patients will undergo an acute procedure in which a catheter is inserted near the heart to ablate a sympathetic nerve, reducing signals that trigger ventricular arrhythmias.
- Trial name
- NCT07501819
- Testing
- Central sympathetic nerve ablation
- Volunteers
- 10 people
- Sponsor
- SymKardia
Arrhythmias
Ventricular Tachyarrhythmia (VT) Storm, Gene Expression in Implantable Cardioverter Defibrillator (ICD) Patients With Electrical Storm
The purpose of the proposed pilot study is to identify factors which are associated with periods of high ventricular arrhythmia burden. This will be performed by analysis of gene expression from peripheral blood samples.
- Trial name
- NCT00284453
- Testing
- Peripheral blood sampling
- Where
- 2 sites in United States
- Volunteers
- 65 people
- Sponsor
- University of Pittsburgh
Arrhythmogenic Cardiomyopathy (AC, ARVD/C), Ventricular Tachycardia (VT)
Treatment Registry of Arrhythmias, Complications and Electrocardiograms in Arrhythmogenic CardioMyopathies
TRACE-ACM is a multicenter, retrospective, observational study of patients with arrhythmogenic cardiomyopathy who received an implantable cardioverter-defibrillator (ICD) and had documented ventricular tachyarrhythmias.
- Conditions
- Arrhythmogenic Cardiomyopathy (AC, ARVD/C), Ventricular Tachycardia (VT), Ventricular Fibrillation, ICD
- Trial name
- TRACE-ACM (NCT07688200)
- Volunteers
- 300 people
- Sponsor
- Policlinico Casilino ASL RMB
Hypertension, Atrial Fibrillation
Effect of Azilsartan on Atrial Fibrillation in Patients With Hypertension
Hypertension and atrial fibrillation (AF) are two major public health problems worldwide. Hypertension is an important risk factor for AF, and the combination of which could significantly increase the risk of cardiovascular…
- Trial name
- AZAF (NCT05841654)
- Testing
- Azilsartan or antihypertensive drugs other than ACEI, ARB or ARNI
- Where
- China
- Volunteers
- 400 people
- Sponsor
- Beijing Tsinghua Chang Gung Hospital
Arrhythmias, Cardiac, Atrial Fibrillation
Clinical Cohort Study - TRUST
The "Long-term Outcome and Predictors for Recurrence after Medical and Interventional Treatment of Arrhythmias at the University Heart Center Hamburg" (TRUST) study is an investor-initiated, single-center, prospective clinical…
- Conditions
- Arrhythmias, Cardiac, Atrial Fibrillation, Atrial Flutter, Ventricular Tachycardia
- Trial name
- TRUST (NCT05521451)
- Where
- Germany
- Volunteers
- 5,000 people, healthy volunteers welcome
- Sponsor
- Universitätsklinikum Hamburg-Eppendorf
Atrio-Ventricular Block
Efficacy and Safety of Left Bundle Area Pacing Vs Right Ventricular Apical Pacing in Patients with Atrioventricular Block
This study will address whether LBBaP is superior to RVAP in terms of safety and efficacy
- Trial name
- NCT06674967
- Where
- Egypt
- Volunteers
- 42 people
- Sponsor
- Assiut University
Premature Ventricular Contractions
Intracardiac Echocardiography-Guided Catheter Ablation for Premature Ventricular Contractions Originating From the Papillary Muscles
This randomized, prospective, parallel, single-blind, multicenter clinical trial investigates the efficacy and safety of intracardiac echocardiography (ICE)-guided catheter ablation versus pressure-sensing catheter ablation alone…
- Trial name
- NCT06898281
- Testing
- intracardiac echocardiography (ICE)-guided catheter ablation, Pressure-sensing catheter ablation alone
- Where
- China
- Volunteers
- 156 people
- Sponsor
- Shanghai Chest Hospital
Pacemaker DDD, Atrioventricular Block
Risk of Pacing-induced Cardiomyopathy
This study will evaluate the association between right ventricular pacing and the risk of pacing-induced cardiomyopathy.
- Conditions
- Pacemaker DDD, Atrioventricular Block, Pacing-Induced Cardiomyopathy
- Trial name
- NCT04269733
- Testing
- Right ventricular pacing
- Where
- Denmark
- Volunteers
- 153 people
- Sponsor
- Aalborg University Hospital
Covid19, Athletes Heart
Effect of CoVid-19 (CoronaVirusDisease-19) and Exercise on Myocardial Fibrosis and Ventricular Arrhythmias
COVID-19 can cause myocarditis, which can cause myocardial fibrosis. This has been shown to increase mortality and morbidity among athletes.
- Conditions
- Covid19, Athletes Heart, Myocarditis Viral, Ventricular Arrythmia
- Trial name
- CoViDEx (NCT04726150)
- Testing
- ILR implantation
- Where
- Belgium
- Volunteers
- 85 people
- Sponsor
- University Hospital, Antwerp
Ventricular Tachycardia (V-Tach)
Combined Pulsed Field and Radiofrequency Energy for Ablation of Ventricular Tachycardia
This will be a single arm study evaluating a new ablation technology for performing catheter ablation of ventricular tachycardia. The technology combines novel pulsed field ablation with radiofrequency ablation.
- Trial name
- DUAL-VT (NCT06816368)
- Testing
- Catheter ablation using sequential radiofrequency and pulsed field ablation
- Where
- 3 sites in Canada
- Volunteers
- 30 people
- Sponsor
- McGill University Health Centre/Research Institute of the McGill University Health Centre
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