Clinical trials: Arrhythmias Ventricular
Ventricular Fibrillation, Cardiac Arrest
SmartCPR Trial: An Analysis of a Waveform-Based Automated External Defibrillation (AED) Algorithm on Survival From Out-of-Hospital Ventricular Fibrillation
This study is designed to examine the impact of an available technology within an automated external defibrillator (AEDs) to improve survival following out-of-hospital cardiac arrest for patients presenting in ventricular…
- Trial name
- SmartCPR (NCT00535106)
- Testing
- Automated external defibrillator (Philips FR2+ AED), SmartCPR, Delayed defibrillation
- Where
- 2 sites in United States, United Kingdom
- Volunteers
- 900 people
- Sponsor
- New York City Fire Department
Ventricular Tachycardia (V-Tach), Implantable Cardioverter Defibrillator (ICD)
Parallel Mapping for Ventricular Tachycardia
Catheter ablation in patients with ventricular tachycardia using a new mapping algorithm called, parallel mapping, that is aimed to increase the specificity of mapping and the outcome of ablation.
- Conditions
- Ventricular Tachycardia (V-Tach), Implantable Cardioverter Defibrillator (ICD), Arrythmia
- Trial name
- NCT04477499
- Where
- United States
- Volunteers
- 44 people
- Sponsor
- The Cleveland Clinic
Ventricular Arrhythmias
Acute Defibrillation Study
The proposed study is designed to characterize defibrillation efficacy in humans for the potential development of a new extravascular implantable cardioverter defibrillator (ICD) system.
- Trial name
- NCT02227121
- Testing
- Defibrillation following induction of VT/VF
- Where
- 7 sites in Hong Kong, Netherlands and 2 more
- Volunteers
- 16 people
- Sponsor
- Medtronic Cardiac Rhythm and Heart Failure
Implantable Defibrillator User, Hypertrophic Cardiomyopathy
Pilot Study of Hypertrophic Cardiomyopathy & Implantable Cardioverter Defibrillator Assessment: (Subcutaneous vs Transvenous)
Pilot randomised trial to assess recruitment for a larger trial to compare the efficacy and adverse effects of the subcutaneous and transvenous ICD in patients with hypertrophic cardiomyopathy (HCM) and indication for ICD…
- Conditions
- Implantable Defibrillator User, Hypertrophic Cardiomyopathy, Implantable Cardioverter Ventricular Lead Dysfunction or Complication, Ventricular Arrythmia
- Trial name
- HICD (NCT05938283)
- Testing
- Implantable Cardioverter Defibrillator implant
- Where
- United Kingdom
- Volunteers
- 5 people
- Sponsor
- Barts & The London NHS Trust
Heart Diseases, Ventricular Arrhythmia
Prognostic Significance of T Wave Alternans
To evaluate whether T Wave Alternans can predict ventricular arrhythmias and sudden cardiac death (SCD) in a prospective epidemiologic natural history study.
- Conditions
- Heart Diseases, Ventricular Arrhythmia, Ventricular Fibrillation, Death, Sudden, Cardiac
- Trial name
- NCT00006501
- Testing
- ECG
- Where
- United States
- Volunteers
- 549 people
- Sponsor
- Columbia University
Ventricular Arrythmia, Lead
Safety and Electrical Performance Evaluation of INVICTA Leads Models Equipped With DF4 Connector
The primary objective of this study is to assess the safety and key electrical performance of the INVICTA leads equipped with DF4 connector: ACTIVE fixation type models (single and dual coil: INVICTA 1CR, INVICTA 2CR) and PASSIVE…
- Conditions
- Ventricular Arrythmia, Lead, ICD, Heart Failure
- Trial name
- FRIENDS (NCT03766919)
- Testing
- Implant of the INVICTA lead
- Where
- 10 sites in France, Italy and 2 more
- Volunteers
- 33 people
- Sponsor
- MicroPort CRM
Premature Ventricular Contraction
Vagal Nerve Stimulation as an Alternative Therapy for Premature Ventricular Contractions
Prospective randomized control pilot study
- Trial name
- NCT06110364
- Testing
- Low-Level Tragus Stimulation, Heart Rate Variability- Biofeedback, Conventional Medical Therapy
- Where
- United States
- Sponsor
- Hunter Holmes Mcguire Veteran Affairs Medical Center
Ablation of Arrhythmias, Premature Ventricular Contractions
Real-Time Intracardiac Echocardiography for Ventricular Arrhythmia Ablation
This study is investigating whether using ultrasound directly inside the heart during ablation of heart rhythm disorders in the ventricles can reduce radiation exposure for patients.
- Conditions
- Ablation of Arrhythmias, Premature Ventricular Contractions, Ventricular Tachycardia, Ventricular Arrhythmia
- Trial name
- REAL-ICE (NCT07201506)
- Testing
- PVC and VT ablation with ICE, PVC and VT ablation without ICE
- Where
- 2 sites in Switzerland
- Volunteers
- 70 people
- Sponsor
- Insel Gruppe AG, University Hospital Bern
HIS Bundle Pacing, Atrial Fibrillation
Ablate and Pace HIS Study
Atrial fibrillation (AF) is the most common sustained cardiac arrhythmia, and estimates suggest its prevalence is increasing. Despite the advances in AF ablation strategies, the outcome of ablation procedures in persistent AF is…
- Trial name
- NCT06152406
- Testing
- Ablation and Pacemaker Implantation
- Where
- United Kingdom
- Volunteers
- 100 people
- Sponsor
- University Hospitals, Leicester
Cardiac Arrhythmia, Ventricular Fibrillation
Emotional Regulation in Patients With Implanted Automatic Defibrillator
The general objective of the study was to evaluate the impact of two emotional regulation programs, one standardized and face-to-face (MBSR: Mindfulness Based Stress Reduction) and, another, implemented through a mobile phone…
- Conditions
- Cardiac Arrhythmia, Ventricular Fibrillation, Ventricular Tachycardia
- Trial name
- NCT04235881
- Testing
- Mindfulness-based stress reduction program, App REM volver a casa
- Where
- Spain
- Volunteers
- 96 people
- Sponsor
- Instituto de Investigación Hospital Universitario La Paz
Cardiac Arrhythmias, Acute Myocardial Infarction (AMI)
Predict Arrhythmia Risk Using Intelligent Software
Cardiac arrhythmias frequently occur in patients admitted to the Coronary Care Unit (CCU). The majority of these patients are treated for an acute myocardial infarction, which carries an increased risk of life-threatening…
- Conditions
- Cardiac Arrhythmias, Acute Myocardial Infarction (AMI), Ventricular Tachycardia (VT), Ventricular Fibrillation
- Trial name
- PARIS (NCT07792694)
- Where
- Netherlands
- Volunteers
- 3,000 people
- Sponsor
- Catharina Ziekenhuis Eindhoven
Ventricular Tachycardia
Magnetic Stimulation to Treat VT Storm
Ventricular Tachycardia storm is a medical emergency characterized by three or more episodes of ventricular arrhythmia within 24 hours and associated with a significantly increased mortality and massive health resource…
- Trial name
- STAR-VT (NCT04043312)
- Testing
- Magstim SuperRapid
- Where
- United States
- Volunteers
- 26 people
- Sponsor
- University of Pennsylvania
Ventricular Tachycardia
FLExAbility Sensor Enabled Substrate Targeted Ablation for the Reduction of VT Study
This clinical investigation is intended to demonstrate the safety and effectiveness of ventricular ablation therapy using the FlexAbility Sensor Enabled Ablation Catheter in patients with drug-refractory monomorphic ventricular…
- Trial name
- LESS-VT (NCT03490201)
- Testing
- Market Approved RF Ablation System, FlexAbility SE Ablation Catheter
- Where
- 32 sites in United States, Australia and 6 more
- Volunteers
- 592 people
- Sponsor
- Abbott Medical Devices
Brugada Syndrome Type 1
Rhythmic Risk of Type 1 Brugada Syndrome and Pulmonary Infundibulum Mapping
Brugada syndrome has been described as the association of a right bundle block with ST segment elevation on the V1 to V3 electrocardiogram in patients with a structurally normal heart.
- Trial name
- SB-CARTO (NCT03572881)
- Testing
- Endocardial mapping
- Where
- France
- Volunteers
- 10 people
- Sponsor
- Hospices Civils de Lyon
Premature Ventricular Contractions
Use of MIBG Scan Images in PVC Ablations
The purpose of this study is to assess if Single Photon Emission Computed Tomography (SPECT) demonstrating cardiac innervation can be integrated into current electrophysiology voltage mapping system and provide improved guidance…
- Trial name
- PVC-MIBG (NCT02279030)
- Testing
- MIBG nuclear scan
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Maryland, Baltimore
Heart Failure, Diastolic, Heart Failure, Systolic
Network Medicine Approaches to Classify Heart Failure With PReserved Ejection Fraction by Signatures of DNA Methylation and Point-of-carE Risk calculaTors (PRESMET)
Heart failure (HF) is a syndrome, resulting from structural or functional impairment of ventricular filling or ejection of blood.
- Conditions
- Heart Failure, Diastolic, Heart Failure, Systolic, Pulmonary Hypertension, Atrial Fibrillation
- Trial name
- PRESMET (NCT05475028)
- Testing
- RRBS
- Where
- Italy
- Volunteers
- 60 people
- Sponsor
- University of Campania Luigi Vanvitelli
Permanent Atrial Fibrillation
Rate Control Therapy Evaluation in Permanent Atrial Fibrillation (RATE-AF)
Atrial fibrillation is a common heart rhythm disturbance, causing important discomfort for patients, a high risk of stroke, frequent hospital admissions and a two-fold increase in death.
- Trial name
- RATE-AF (NCT02391337)
- Testing
- Bisoprolol, Digoxin
- Where
- 2 sites in United Kingdom
- Volunteers
- 161 people
- Sponsor
- University of Birmingham
Left Bundle Branch Block, Left Bundle Branch Area Pacing
UHF ECG in LBBB and Response to CRT Prediction
The main objective of the project is to demonstrate that in patients with heart failure and QRS complex of nonRBBB morphology lasting over 130 ms, UHF-ECG can differentiate patients with trueLBBB from IVCD better than existing…
- Conditions
- Left Bundle Branch Block, Left Bundle Branch Area Pacing, Biventricular Pacing, Intraventricular Conduction Delay
- Trial name
- UHF BLOCK (NCT07057544)
- Testing
- LBBAP CRT device implantation, BVP-CRT
- Where
- Czechia
- Volunteers
- 200 people
- Sponsor
- Faculty Hospital Kralovske Vinohrady
Premature Ventricular Complex, Ventricular Arrythmia
Non-Invasive 3D Mapping for Identifying Origin and Preferential Propagation of Ventricular Arrhythmias
This study will measure the diagnostic sensitivity and specificity of the Medtronic CardioInsight wearable 252 electrode vest in predicting the chamber of origin of premature ventricular complexes (PVCs) and compare its…
- Trial name
- NCT03831516
- Testing
- Non Invasive Electroanatomical Mapping
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Northwell Health
Paroxysmal Supraventricular Tachycardia
Oral Verapamil in Acute Paroxysmal Supra Ventricular Tachycardia(PSVT) Recurrence Control
PSVT is a common rhythm disorder in emergency department which can be recurrent in some cases. Intravenous Adenosine is the drug of choice in PSVT control in acute settings but is a very short acting agent.
- Trial name
- NCT01655316
- Testing
- Verapamil
- Volunteers
- 90 people
- Sponsor
- Tehran University of Medical Sciences
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