Clinical trials: Art
HIV, AIDS
Resistance Testing to Improve Management of Virologic Failure in Sub-Saharan Africa
The study design is an open-label, randomized controlled trial. The study will be conducted at study sites in Uganda and South Africa.
- Trial name
- REVAMP (NCT02787499)
- Testing
- HIV-1 RNA Resistance Testing
- Where
- 2 sites in South Africa, Uganda
- Volunteers
- 840 people
- Sponsor
- Massachusetts General Hospital
Malaria
Efficacy of Amodiaquine-artesunate in Children Aged 6-59 Months With Uncomplicated P. Falciparum Malaria
We will be studying the clinical efficacy of amodiaquine-artesunate currently being studied in an intermittent preventive therapy in infants (IPTi)trial in the same area in order to correlate preventive efficacy seen in IPTi with…
- Trial name
- IPTi DRWG (NCT00425763)
- Testing
- AQAS
- Where
- Kenya
- Volunteers
- 110 people
- Sponsor
- Centers for Disease Control and Prevention
HIV Antiretroviral Therapy (ART) Adherence
Optimizing Care Delivery to Support Reengagement in PLWH Returning to HIV Care After Treatment Lapses in Zambia
1.0 Introduction The scale-up of human immunodeficiency virus (HIV) treatment services has expanded rapidly in Zambia, facilitated by evolution of the HIV response from centralized services to decentralized care and now towards…
- Trial name
- Reengagement (NCT06803316)
- Where
- Zambia
- Volunteers
- 658 people
- Sponsor
- Centre for Infectious Disease Research in Zambia
Severe Malaria
Malaria Treatment With Injectable ArteSunate
The MATIAS study aims to demonstrate through limited scope implementation studies how injectable artesunate may be progressively rolled out nationwide in the Democratic Republic of the Congo as the preferred treatment for severe…
- Trial name
- MATIAS (NCT01828333)
- Testing
- No intervention
- Where
- 9 sites in Democratic Republic of the Congo
- Volunteers
- 350 people
- Sponsor
- Swiss Tropical & Public Health Institute
HIV Antiretroviral Therapy (ART) Adherence, Alcohol Abuse
Reducing Hazardous Alcohol Use and Optimizing Treatment as Prevention Among Men Living With HIV in Risk Environments
The investigators developed the Kisoboka ("It is possible") Intervention to address limitations of existing evidence-based interventions to optimize treatment as prevention among men living with HIV who drink alcohol at hazardous…
- Conditions
- HIV Antiretroviral Therapy (ART) Adherence, Alcohol Abuse, HIV Infection, Alcohol Use Disorder
- Trial name
- Kisoboka (NCT06771843)
- Testing
- Kisoboka, Behavioral Economics, Motivational Interviewing
- Where
- Uganda
- Volunteers
- 716 people
- Sponsor
- San Diego State University
HIV Infections
A Study of Thalidomide in HIV-Infected Patients Who Are Receiving HAART
To ascertain the effect of thalidomide on immune responses to vaccination with polyvalent pneumococcal polysaccharide vaccine and tetanus toxoid in HIV-infected patients; particularly, on markers of immune activation and…
- Trial name
- NCT00002392
- Testing
- Thalidomide
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- Rockefeller University
Stage IV Adult Soft Tissue Sarcoma, Sarcoma,Soft Tissue
(SBRT) and (ART) for Pulmonary Metastases From Soft Tissue Sarcomas
This is a prospective study to document the local control rates with SBRT specifically for pulmonary metastases from soft tissue sarcoma.
- Trial name
- NCT01949506
- Testing
- SBRT
- Where
- United States
- Volunteers
- 9 people
- Sponsor
- Medical College of Wisconsin
Aging
Chinese Art Activities or Combined With Peer Group Participation on Psychological Well Being
The goal of this trial is to evaluate the effects of two interventions : routine care plus Chinese Art Activities(+CAA) and routine care plus Chinese Art Activities combined with Peer Group Participation (+CAA+PGP) on…
- Trial name
- CAA+PGP#PWB (NCT06841133)
- Testing
- Chinese Art Activities, Chinese Art Activities combined with Peer Group Participation (PGP)
- Where
- 3 sites in China
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Prince of Songkla University
HIV, Community Health Workers
The Impact of Home Delivery of Antiretroviral Therapy on Virological Suppression
Home delivery of antiretroviral therapy (ART) by community health workers (CHWs) has the potential to reduce key barriers to ART care retention.
- Conditions
- HIV, Community Health Workers, Antiretroviral Therapy, Highly Active
- Trial name
- NCT02711293
- Testing
- ART home delivery, Enhanced nutrition counseling
- Where
- Tanzania
- Volunteers
- 2,172 people
- Sponsor
- Harvard School of Public Health (HSPH)
HIV Infections
A Study to Investigate the Use of VH3810109 With or Without Fostemsavir (FTR) to Reduce the Size and Activity of the Viral Reservoir in People Living With HIV
This study investigates the use of VH3810109 with or without FTR to reduce the size and activity of the HIV viral reservoir in two sub-populations of people living with HIV: treatment-naïve adults (Population 1) and…
- Trial name
- ENTRANCE (NCT07053384)
- Testing
- VH3810109, Fostemsavir (FTR), SOC INSTI-based ART
- Where
- 41 sites in United States, Belgium and 4 more
- Volunteers
- 107 people
- Sponsor
- ViiV Healthcare
Anxiety
Characterization of Emotional Response Profiles Triggered by a Digital Artwork of Musicalized Impressionist Paintings
Global warming, progressing at a rapid pace in Canada, is causing severe consequences for ecosystems and human health. Rising temperatures accelerate glacier melting, increase heat waves, and disrupt biodiversity.
- Trial name
- NeuroArt (NCT06605092)
- Testing
- Emotional stimulation
- Where
- Canada
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Centre integre universitaire de sante et de services sociaux du Centre-Sud-de-l'Île-de-Montréal
Resilience, Psychological, Joy of Living
Effects of Art-Based Group Reminiscence Therapy on Resilience and Joy of Living in Older Adults
This study will examine whether art-based group reminiscence therapy can improve psychological resilience and joy of living in adults aged 60 years and older.
- Trial name
- NCT07905521
- Testing
- Art-Based Group Reminiscence Therapy
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Tuğçe KAPLAN UYAN
Malaria,Falciparum
Effectiveness and Safety of Artesunate-Amodiaquine and Artemether-Lumefantrine for the Treatment of Malaria in Yaounde
Artesunate-amodiaquine and artemether-lumfantrine are currently being used for the treatment of uncomplicated Plasmodium falciparum in Cameroon.
- Trial name
- NCT04565184
- Testing
- Artesunate-amodiaquine combination, Artemether, Lumefantrine Drug Combination
- Where
- Cameroon
- Volunteers
- 242 people
- Sponsor
- University of Yaounde 1
Cancer, Psychological Distress
Patient's and Caregiver's Expectations and Preferences Concerning Art Therapy Activities for Cancer Support
Cancer patients and their caregivers often experience difficulties in coping with the cancer diagnosis and the treatment that follows.
- Trial name
- PREFERENCE (NCT03705052)
- Testing
- Questionnaire
- Where
- Belgium
- Volunteers
- 169 people, healthy volunteers welcome
- Sponsor
- General Hospital Groeninge
Malaria,Falciparum
Gametocytocidal and Transmission-blocking Efficacy of ASAQ and ALAQ With or Without PQ in Mali
The purpose of this study is to compare the gametocytocidal and transmission reducing activity of artesunate-amodiaquine (ASAQ) and artemether-lumefantrine-amodiaquine (ALAQ) with and without a single dose of 0.25mg/kg primaquine…
- Trial name
- NECTAR4 (NCT05550909)
- Testing
- Artesunate-amodiaquine combination, Primaquine Phosphate, Artemether-lumefantrine
- Where
- Mali
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- London School of Hygiene and Tropical Medicine
HIV/AIDS, Substance Abuse
Directly Observed Antiretroviral Therapy Among Active Drug Users
The goal of this randomized, controlled trial is to compare the effectiveness of a community-based program of providing supervised antiretroviral therapy to HIV-positive drug users, compared to having the patients take the…
- Trial name
- NCT00367172
- Testing
- Directly Administered Antiretroviral Therapy
- Where
- United States
- Volunteers
- 125 people
- Sponsor
- Yale University
HIV Infections
Effects on the Immune System of Anti-HIV Drugs in Patients Recently Infected With HIV
The purpose of this study is to find out whether these powerful combinations of anti-HIV drugs are safe and effective for use in patients in the early stages of HIV infection and to find out how patients' immune systems react to…
- Trial name
- NCT00001119
- Testing
- Tetanus Toxoid Vaccine, Indinavir sulfate, Lamivudine/Zidovudine
- Where
- 12 sites in United States, Australia
- Volunteers
- 288 people, healthy volunteers welcome
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
Friedreich Ataxia
Evaluation of the Effect of Artesunate in Friedreich Ataxia (FA)
This dose-escalation study is aimed at investigating a novel application for artesunate in the treatment of Friedreich ataxia. It will evaluate this novel application of oral artesunate using a surrogate biological marker as…
- Trial name
- ARTEMIS (NCT04921930)
- Testing
- Artesunate Oral Product
- Where
- France
- Volunteers
- 20 people
- Sponsor
- Institut National de la Santé Et de la Recherche Médicale, France
Hiv
Early Administration of Romidepsin and 3BNC117 in Treatment-naïve HIV Patients Starting ART
To evaluate the effect of early viral reactivation by latency reversing agents (LRA) and/or administration of potent broadly neutralizing antibodies (bNAb) on the size of the latent HIV-1 reservoir in treatment naïve HIV-1…
- Trial name
- eCLEAR (NCT03041012)
- Testing
- Romidepsin, 3BNC117, Antiretrovirals
- Where
- 7 sites in Denmark, United Kingdom
- Volunteers
- 60 people
- Sponsor
- Aarhus University Hospital
HIV, Malnutrition
Study of Impacts of Food Supplementation on Malnourished HIV-Infected Adults in Kenya
The purpose of the study is to test whether food supplementation of malnourished HIV-infected adults (both pre-ART and ART) in resource constrained settings improves their nutritional status, clinical status, effectiveness of…
- Conditions
- HIV, Malnutrition, HIV Infections
- Trial name
- NCT00838292
- Testing
- fortified blended flour - Insta Foundation Plus (with whey protein concentrate), nutrition counseling
- Where
- 6 sites in Kenya
- Volunteers
- 1,049 people
- Sponsor
- Academy for Educational Development