Clinical trials: Arterial Aneurysm
Abdominal Aorta Aneurism, Peripheral Arterial Disease
Developing Trustworthy Artificial Intelligence (AI)-Driven Tools to Predict Vascular Disease Risk and Progression: the Prospective VASCUL-AID Study
Introduction: Peripheral arterial disease (PAD) and abdominal aortic aneurysm (AAA) are vascular conditions associated with significant morbidity and mortality, with 25% of AAA patients and 23% of PAD patients being at a high…
- Trial name
- VASCUL-AID-PRO (NCT07187700)
- Volunteers
- 1,100 people
- Sponsor
- Amsterdam UMC
Intracranial Aneurysm, Brain Arterial Disease
Safety, Performance and Usability of BALT Medical Devices: The EVIDENCE Post Marketing Clinical Follow-up Platform
BALT has designed an electronic platform to continue collecting clinical data as part of the post-marketing clinical follow-up of its devices.
- Conditions
- Intracranial Aneurysm, Brain Arterial Disease, Acute Ischemic Stroke, Peripheral Vascular Diseases
- Trial name
- EVIDENCE (NCT04927156)
- Testing
- BALT medical devices
- Where
- 12 sites in France, Germany and 1 more
- Volunteers
- 10,000 people
- Sponsor
- Balt Extrusion
Peripheral Arterial Hemorrhage, Arteriovenous Malformation
The Clinical Application of Peripheral Embolization Coil Systems in Arteriovenous Embolization Within the Peripheral Vasculature
Evaluation of the Safety and Effectiveness of the Peripheral Embolization Coil System Manufactured by Suzhou Zhongtian Medical Instruments Co., Ltd.
- Conditions
- Peripheral Arterial Hemorrhage, Arteriovenous Malformation, Arteriovenous Fistula, Peripheral Aneurysm
- Trial name
- NCT07156409
- Testing
- Peripheral Embolization Coil System
- Volunteers
- 139 people
- Sponsor
- Suzhou Zenith Vascular SciTech Limited
Aortic Infections and Inflammations, Mycotic Aneurysm
Study of the Aortic and Large Arterial Vessel Infections
Aortic or large arterial vessel infections are rare but serious infections. Their management is based on French and American expert opinions.
- Conditions
- Aortic Infections and Inflammations, Mycotic Aneurysm, Arterial Infections and Inflammations, Prosthetic Infection
- Trial name
- Repia (NCT05660733)
- Where
- France
- Volunteers
- 500 people
- Sponsor
- Central Hospital, Nancy, France
Arterial Aneurysm Wall Enhancement on HRMRI
Risk Assessment and Mechanism Analysis of Intracranial Multiple Aneurysm Instability Based on High-resolution Magnetic Resonance, Imaging Histology and Hemodynamics
This project proposes to establish a prospective cohort of MIA based on a preexisting multicenter MIA database and to combine multidimensional methods such as high-resolution magnetic resonance, hemodynamics, ambulatory blood…
- Trial name
- NCT06539767
- Where
- 2 sites in China
- Volunteers
- 1,000 people
- Sponsor
- Zhujiang Hospital
Cotinine Levels, Arterial Aneurysm Wall Enhancement on HRMRI
A Study on the Correlation Between Cotinine Levels and Aneurysm Wall Enhancement on HRMRI.
This study aims to collect clinical, laboratory, and imaging data from patients with unruptured intracranial aneurysms, and collect blood or urine samples for cotinine testing.
- Trial name
- NCT06447714
- Testing
- smoke
- Where
- China
- Volunteers
- 450 people, healthy volunteers welcome
- Sponsor
- Zhujiang Hospital
PAD - Peripheral Arterial Disease, AAA - Abdominal Aortic Aneurysm
Retrospective Post-Market Clinical Follow-Up Study of GORE-TEX® Vascular Grafts and GORE® PROPATEN® Vascular Graft in Peripheral Artery Disease, Aortic Aneurysms, and Dialysis Access
This multicenter, single-arm retrospective registry (chart review) is being conducted to confirm the clinical performance and safety of GORE-TEX® Vascular Grafts and GORE® PROPATEN® Vascular Graft throughout the device functional…
- Conditions
- PAD - Peripheral Arterial Disease, AAA - Abdominal Aortic Aneurysm, End-Stage Renal Disease
- Trial name
- NCT05124184
- Testing
- GORE® PROPATEN® Vascular Graft, GORE-TEX® Vascular Grafts
- Where
- 8 sites in France, Italy and 1 more
- Volunteers
- 356 people
- Sponsor
- W.L.Gore & Associates
Aortic Aneurysm, Aortic Aneurysm Abdominal
Prophylactic Suture Line Sealing With NE'X Glue R-eco in Cardiac and Vascular Surgery
This clinical study aims to evaluate the effectiveness and safety of using NE'X Glue R-eco to seal suture lines. The adhesive will be applied to reduce the risk of suture line bleeding in cardiac or vascular repair surgeries, a…
- Conditions
- Aortic Aneurysm, Aortic Aneurysm Abdominal, Valve Stenoses, Aortic, Valve Regurgitation, Mitral
- Trial name
- CLOSURE (NCT06918496)
- Testing
- Surgical placement of a prosthetic or biologic graft (patch), or an allograft for cardiac and (cardio)vascular repair.
- Where
- 2 sites in Belgium, Poland
- Volunteers
- 60 people
- Sponsor
- Grena Biomed Limited
Vasodilation, Arterial Stiffness
Targeting ER Stress in Vascular Dysfunction
Aging and obesity are both risk factors for cardiovascular disease (CVD). One process that links both of these conditions to CVD is vascular dysfunction.
- Trial name
- NCT04001647
- Testing
- Acetylcholine, Sodium Nitroprusside, Ascorbic Acid
- Where
- United States
- Volunteers
- 17 people, healthy volunteers welcome
- Sponsor
- Colorado State University
Peripheral Artery Disease, Abdominal Aortic Aneurysm
Endovascular Treatment of Aorto-iliac Disease Using in Situ Fenestration
In situ fenestration (ISF) could represent an alternative in the treatment of aorto-iliac disease when usual techniques are not available. The aim of this study was to present the results of ISF in aorto-iliac disease.
- Trial name
- PREFISIT (NCT04062734)
- Where
- France
- Volunteers
- 30 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Dissection Carotid Artery, Dissection Arterial
Next Generation Sequencing Analysis of Patients with Spontaneous Dissection of Cervical Arteries
The goal of this observational study is to analyze the existence of a genetic predisposition in patients with spontaneous dissections of the cervical arteries (SCeAD). The main questions it aims to answer are: 1.
- Conditions
- Dissection Carotid Artery, Dissection Arterial, Dissecting Aneurysm
- Trial name
- NASCeAD (NCT06862063)
- Testing
- Genetic testing
- Where
- Italy
- Volunteers
- 145 people
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Aneurysm Abdominal, Arterial Aneurysm
Italian Multicentric Study on the Treatment of Visceral Aneurysms With the Flow Diversion Stent Derivo Peripher and Derivo 2
This is a multicentric voluntary observational study with a retrospective evaluation of prospectively collected data concerning the treatment of visceral aneurysms with flow diversion stent Derivo Peripher and Derivo 2 (DED…
- Trial name
- DEDICATE (NCT06325371)
- Testing
- Visceral aneurysm stenting
- Where
- Italy
- Volunteers
- 100 people
- Sponsor
- University of Turin, Italy
Abdominal Aortic Aneurysm, Surgery
ACT Guided Heparinization During Open Abdominal Aortic Aneurysm Repair.
Aim of the ACTION-1 study is to determine whether ACT guided heparinization decreases thrombo-embolic complications (TEC) and mortality after elective open AAA surgery, without causing more bleeding complications.
- Conditions
- Abdominal Aortic Aneurysm, Surgery, Arterial Disease
- Trial name
- ACTION-1 (NCT04061798)
- Testing
- ACT guided heparinization, 5 000 IU of heparin
- Where
- 22 sites in Germany, Netherlands
- Volunteers
- 294 people
- Sponsor
- Dijklander Ziekenhuis
Wide Neck Bifurcation Intracranial Aneurysms, Intracranial Aneurysms
The WEB-IT Clinical Study
The study is a prospective, multicenter single-arm cohort. Patients with wide neck bifurcation aneurysms (WNBAs) have few choices for safe and effective endovascular treatment.
- Trial name
- WEB-IT (NCT02191618)
- Testing
- WEB
- Where
- 32 sites in United States, Canada and 4 more
- Volunteers
- 150 people
- Sponsor
- Microvention-Terumo, Inc.
Intracranial Arterial Aneurysm
Safety and Efficacy of the Surpass Evolve Flow Diverter in Treating Intracranial Aneurysms
Safety and Efficacy of the Surpass Evolve Flow Diverter in Treating Intracranial Aneurysms
- Trial name
- NCT06731946
- Testing
- Flow diverting
- Where
- China
- Volunteers
- 150 people
- Sponsor
- Yibin Fang
Cardio-pulmonary Bypass, AORTIC VALVE DISEASES
Clinical Validation of a Novel Handsfree Doppler Ultrasound Device, RescueDoppler, in Adult Cardiac Surgery Patients
The goal of this study is to evaluate a new device called RescueDoppler (RD), which measures continuous blood flow in the common carotid artery. The device is handsfree and operator- independent.
- Conditions
- Cardio-pulmonary Bypass, AORTIC VALVE DISEASES, Coronary Arterial Disease (CAD), Aortic Aneurysm of the Proximal Arch
- Trial name
- RD_CPB (NCT06637540)
- Testing
- RescueDoppler
- Where
- 3 sites in Norway
- Volunteers
- 42 people
- Sponsor
- St. Olavs Hospital
Intracranial Hemorrhage Ruptured Aneurysm
International Subarachnoid Aneurysm Trial II
The purpose of this study is to compare the clinical outcome of surgical clipping and endovascular coiling for ruptured intracranial aneurysms not included in the original ISAT Study.
- Trial name
- ISATII (NCT01668563)
- Testing
- surgical management, Endovascular management
- Where
- 6 sites in United States, Canada and 1 more
- Volunteers
- 1,724 people
- Sponsor
- Centre hospitalier de l'Université de Montréal (CHUM)
Aging, Aortic Aneurysm, Abdominal
The Intersectional Viborg Screening Program: Cost-(Effectiveness) of Screening for Diabetes and Cardiovascular Diseases
This is an intersectional and interdisciplinary screening program in Viborg Municipality, including 67 years old citizens. This observational study will estimate the cost-effectiveness of a combined screening program for the…
- Conditions
- Aging, Aortic Aneurysm, Abdominal, Hypertension, Mass Screening
- Trial name
- VISP (NCT03395509)
- Where
- Denmark
- Volunteers
- 4,500 people, healthy volunteers welcome
- Sponsor
- Central Jutland Regional Hospital
Rheumatoid Arthritis, Ankylosing Spondylitis
PatientSpot Formerly Known as ArthritisPower
Patient Power is a patient research network and database (registry) to collect prospective information about demographics, self-reported diagnoses and medications, and willingness to participate in research from participants with…
- Conditions
- Rheumatoid Arthritis, Ankylosing Spondylitis, Fibromyalgia, Gout
- Trial name
- NCT03840928
- Where
- United States
- Volunteers
- 40,000 people, healthy volunteers welcome
- Sponsor
- Global Healthy Living Foundation
Aortic Aneurysm, Abdominal, Carotid Stenosis
Screening and Access to Health Care for Vascular Disease
This is a pilot study designed to validate our methods of recruitment, screening and data collection in the community. The project will help to establish the feasibility of the study design to lay the groundwork for a potentially…
- Conditions
- Aortic Aneurysm, Abdominal, Carotid Stenosis, Peripheral Arterial Disease
- Trial name
- NCT01889485
- Where
- United States
- Volunteers
- 190 people, healthy volunteers welcome
- Sponsor
- Endeavor Health