Clinical trials: Arterial Aneurysm
Coronary Artery Disease, Aortic Stenosis
The CardioPAT Project: A Randomized Trial
The purpose of this study is to determine whether intra- and postoperative use of the cardioPAT® cell saver decreases the need for allogenic red blood cell transfusion in patients, who undergo open heart surgery (with…
- Conditions
- Coronary Artery Disease, Aortic Stenosis, Aortic Insufficiency, Mitral Insufficiency
- Trial name
- NCT02058134
- Testing
- cardioPAT cell saver
- Where
- Denmark
- Volunteers
- 68 people
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Intracranial Aneurysm
Post Market Clinical Follow-up (PMCF)Study of the Contour Neurovascular SystemTM
Cerus Endovascular is sponsoring a prospective, multi-center PMCF to document the safety and performance of the Contour Neurovascular System™ (hereinafter "Contour") in normal medical use.
- Trial name
- NCT04579081
- Testing
- Contour Neurovascular System
- Sponsor
- Cerus Endovascular, Inc.
Intracranial Aneurysm
Nomogram for Predicting In-stent Stenosis After Pipeline Embolization Device Treatment in Patients With Intracranial Aneurysm
Intracranial aneurysms (IAs) are the primary cause of non-traumatic subarachnoid hemorrhage with high morbidity and mortality. Flow diverters, such as pipeline embolization devices (PEDs), are among the most effective methods for…
- Trial name
- PED-ISS (NCT06715930)
- Testing
- Interventional treatment
- Where
- China
- Volunteers
- 1,500 people
- Sponsor
- Beijing Tiantan Hospital
Visceral Artery Aneurysm, Mesenteric Artery Ischemia
European Multicentre Study of Long-term Results Following Visceral Arteries Revascularization: the E-VisAR Study
Visceral arteries pathologies are a broad-spectrum of conditions with an extremely low incidence, estimated at 9.2% and 6.2% per 100,000 inhabitants for chronic and acute mesenteric ischemia, respectively, and 0.01-0.2% for…
- Conditions
- Visceral Artery Aneurysm, Mesenteric Artery Ischemia, Renal Artery Aneurysm, Renal Artery Stenosis
- Trial name
- E-VisAR (NCT06913530)
- Volunteers
- 500 people
- Sponsor
- Azienda Ospedaliero-Universitaria di Modena
Aneurysm Cerebral, Bifurcation
LUMENS-1 EU EFS CIP
The primary objective of this clinical investigation is to evaluate the early safety and feasibility of the LuSeed Aneurysm Embolization System for treating unruptured intracranial aneurysms (IA).
- Conditions
- Aneurysm Cerebral, Bifurcation, Unruptured Intracranial Aneurysm, Saccular Aneurysm
- Trial name
- NCT06761365
- Testing
- LuSeed Aneurysm Embolization System
- Where
- 6 sites in Bulgaria, Germany and 2 more
- Volunteers
- 30 people
- Sponsor
- LuSeed Vascular LTD.
Peripheral Arterial Disease, Carotid Stenosis
EValuation of Systemic Atherothrombosis in Patients With ARTerial Disease of the Lower Limbs
The purpose of this study is to determine the prevalence and risk factors, at the time of the diagnosis of PAD, for asymptomatic carotid stenosis and abdominal aortic aneurysm.
- Conditions
- Peripheral Arterial Disease, Carotid Stenosis, Abdominal Aortic Aneurysm
- Trial name
- EVART (NCT01224600)
- Testing
- patients with newly diagnosed PAD (<1year)
- Where
- 115 sites in Belgium, France
- Volunteers
- 1,056 people
- Sponsor
- Institut de l'Atherothrombose
Brain Aneurysm
Trial on Endovascular Aneurysm Management
The management of patients with unruptured aneurysms is controversial. Patients with unruptured aneurysms may suffer intracranial hemorrhage, but the incidence of this event is still debated.
- Trial name
- TEAM (NCT00537134)
- Testing
- Embolization, coiling
- Where
- 9 sites in United States, Canada and 2 more
- Volunteers
- 80 people
- Sponsor
- Centre hospitalier de l'Université de Montréal (CHUM)
Vasodilation, Diabetes Mellitus, Type 2
Impact of Regional Vibration Application and Flow Mediated Dilation on Brachial Artery Hemodynamics
Application of vibration has been previously shown to affect tissue perfusion and utilized in different branches of medicine. Little is known about the acute impact of vibration application on peripheral artery hemodynamics.
- Trial name
- VMD (NCT05492071)
- Testing
- Local Vibration Application Following Flow Mediated Dilation, Flow mediated dilation
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Istanbul University
Intracranial Aneurysm, Aneurysm
Coated Mongolian Aneurysm Treatment Study 1
The purpose of this study is to assess safety and effectiveness of the p64 MW HPC or p48 MW HPC Flow Modulation Device under Dual Antiplatelet Medication.
- Conditions
- Intracranial Aneurysm, Aneurysm, Vascular Diseases
- Trial name
- COMATS 1 (NCT04305626)
- Testing
- Endovascular treatment of intracranial aneurysms
- Where
- Mongolia
- Volunteers
- 90 people
- Sponsor
- Phenox GmbH
Subarachnoid Hemorrhage, Cerebral Aneurysm
Amnesia After Surgery for Anterior Communicating Aneurysm： High Resolution Magnetic Resonance (MR) Imaging Findings
To clarify whether amnesia after treatment of anterior communicating aneurysm (ACoA)is related to infarcts caused by occlusion or damage of the perforating artery of the ACoA, we used 3.0-T 3D high resolution MR imaging to…
- Conditions
- Subarachnoid Hemorrhage, Cerebral Aneurysm, Amnesia
- Trial name
- NCT01919775
- Volunteers
- 14 people
- Sponsor
- Tohoku University
Subarachnoid Hemorrhage
Lumbar Drain With Intrathecal Nicardipine in Aneurysmal Subarachnoid Hemorrhage
The purpose of this study is to determine the effectiveness of prophylactic administration of intra-thecal nicardipine though lumbar cerebrospinal fluid drain in prevention of symptomatic vasospasm in patients with subarachnoid…
- Trial name
- NCT07246629
- Testing
- Normal Saline, Nicardipine
- Where
- United States
- Volunteers
- 214 people
- Sponsor
- Wake Forest University Health Sciences
Intracranial Aneurysms
Efficacy Trial of Intracranial Aneurysm Treatment Using Two Different Endovascular Techniques
To date the standard non-surgical treatment strategy for treating un-ruptured intracranial aneurysms is the use of either coils or self-expandable stents.
- Trial name
- NCT01084681
- Testing
- Endovascular treatment of intracranial aneurysms, Endovascular treatment of intracranial aneurysm with coils
- Where
- Germany
- Volunteers
- 160 people
- Sponsor
- Balt International
Intracranial Arterial Aneurysm
Safety and Efficacy of the Surpass Evolve Flow Diverter in Treating Intracranial Aneurysms
Safety and Efficacy of the Surpass Evolve Flow Diverter in Treating Intracranial Aneurysms
- Trial name
- NCT06731946
- Testing
- Flow diverting
- Where
- China
- Volunteers
- 150 people
- Sponsor
- Yibin Fang
Intracranial Aneurysm, CT Angiography
Stepped-Wedge Cluster Randomized Trial of AI-Assisted CTA Detection for Intracranial Aneurysms in Regional Hospitals
This study (IDEAL 2) is a nationwide stepped-wedge cluster-randomized trial designed to prospectively enroll over 14,400 patients undergoing outpatient head CT angiography (CTA).
- Conditions
- Intracranial Aneurysm, CT Angiography, AI (Artificial Intelligence), Cluster Randomized Trial
- Trial name
- IDEAL2 (NCT07124624)
- Testing
- AI-Assisted CTA Interpretation, Standard CTA Interpretation
- Volunteers
- 14,400 people, healthy volunteers welcome
- Sponsor
- Jinling Hospital, China
Coronary Artery Ectasia
Endothelial NO Synthase Polymorphic Gene in Coronary Artery Dilation Disease
Introduction: The coronary artery dilatations disease (Coronary artery aneurysm/coronary artery ectasia) characterized by inappropriate coronary artery dilations.
- Trial name
- NCT06220682
- Testing
- The specific genetic PCR laboratory test were performed for all selected patients for eNOS SNPs
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Cairo University
Brain Aneurysm
Aneurysm Genetic Risk in Patients With QIB Changes
Intracranial aneurysm rupture is a leading cause of hemorrhagic strokes which carry high mortality and disability rates as well as high healthcare costs.
- Trial name
- AnGen (NCT05317169)
- Where
- United States
- Volunteers
- 120 people
- Sponsor
- University of California, Los Angeles
Intracranial Aneurysm
Population-based Investigation of Aneurysm Incidence
Most intracranial aneurysms are found accidentally in neurovascular imaging. And these inspection methods are limited by the problems of instrument fixation, radiation, time-consuming, contrast agent toxicity and so on.
- Trial name
- NCT06412783
- Testing
- blood test
- Where
- China
- Volunteers
- 4,711 people, healthy volunteers welcome
- Sponsor
- Beijing Tiantan Hospital
Chronic Stable Angina, Unstable Angina
The Role of Alcohol Consumption in the Aetiology of Different Cardiovascular Disease Phenotypes: a CALIBER Study
The association between alcohol consumption and cardiovascular disease (CVD) has mostly been examined using broad endpoints or cause-specific mortality.
- Conditions
- Chronic Stable Angina, Unstable Angina, Coronary Heart Disease Not Otherwise Specified, Acute Myocardial Infarction
- Trial name
- NCT01864031
- Where
- United Kingdom
- Volunteers
- 2,240,000 people
- Sponsor
- University College, London
Intracranial Aneurysm, Subarachnoid Hemorrhage
HYdrogel Coil Versus Bare Platinum Coil in Recanalization Imaging Data Study
HYBRID study is prospective randomized open label controlled multi center trial, to compare Hydrocoil and bare platinum coil for recanalization after endovascular treatment of intracranial aneurysms.
- Trial name
- HYBRID (NCT01516658)
- Testing
- Hydrogel coil, Bare platinum coil
- Where
- 2 sites in Japan
- Volunteers
- 431 people
- Sponsor
- Kobe City General Hospital
Intracranial Aneurysm
The Registry to Study Safety and Performance of the CORDIS Vascular Reconstruction Device and Delivery System
The objective of the registry is to evaluate the real world safety and performance of the CORDIS ENTERPRISE™ Vascular Reconstruction Device and Delivery System (VRD) to facilitate endovascular coil embolization of intracranial…
- Trial name
- SUNRISE (NCT00486226)
- Testing
- Vascular Reconstruction Device
- Where
- Belgium
- Volunteers
- 105 people
- Sponsor
- Codman & Shurtleff