Clinical trials: Arterial Aneurysm
Juxtarenal Aortic Aneurysm, Suprarenal Aortic Aneurysm
Evaluation of the Cook Custom Aortic Endograft, the Zenith t-Branch Endovascular Graft, and Surgeon-Modified Endograft in Treating Aortic Pathologies
This is a single-center study to evaluate the safety and effectiveness of three investigational devices, the Cook Custom Aortic Endograft, the Zenith t-Branch Endovascular Graft, and the Surgeon-Modified Endografts in the…
- Conditions
- Juxtarenal Aortic Aneurysm, Suprarenal Aortic Aneurysm, Thoracoabdominal Aortic Aneurysm, Penetrating Aortic Ulcer
- Trial name
- NCT02043691
- Testing
- Cook Custom Aortic Endograft, Zenith t-Branch Endovascular Graft, Surgeon-Modified Endograft
- Where
- United States
- Volunteers
- 410 people
- Sponsor
- University of Alabama at Birmingham
Intracranial Aneurysm
Contrast-enhanced Magnetic Resonance Angiography Investigation of Intracranial Aneurysms and Prospective Study of Risk Factors
This is a prospective observational registry with intent to detect the prevalence of intracranial aneurysms with contrast-enhanced MR angiography (CE-MRA) at 1.5T, and to determine the risk factors such as high blood pressure and…
- Trial name
- EIIA (NCT00997698)
- Where
- China
- Volunteers
- 4,000 people, healthy volunteers welcome
- Sponsor
- Second Military Medical University
Healthy Volunteers, Vascular Ehlers Danlos Syndrome
Non-Invasive Quantitative Imaging of Human Local Arterial Wall Elasticity Using Supersonic Shear Imaging
Arterial stiffness is associated with increased risk of cardiovascular events and death. Most of existing technique need dedicated device for arterial stiffness evaluation and indirect calculation of intra arterial pressure.
- Trial name
- ULTRAFASTECHO (NCT01096264)
- Testing
- SSI and SphygmoCor® evaluations
- Where
- France
- Volunteers
- 145 people, healthy volunteers welcome
- Sponsor
- French Cardiology Society
Intracranial Aneurysm
PARAT PLUS (The Tubridge Plus For The Treatment Of Wide-Necked Intracranial Aneurysms)
A trial to evaluate the safety and efficacy of the Tubridge Plus flow-diverter stent for the treatment of intracranial wide-necked aneurysms.
- Trial name
- NCT05898893
- Testing
- Microport NeuroTech Tubridge Plus flow-diverter Stent
- Where
- 8 sites in China
- Volunteers
- 99 people
- Sponsor
- MicroPort NeuroTech Co., Ltd.
Cerebral Aneurysm
Ticagrelor vs Clopidogrel for Platelet Inhibition in Stenting for Cerebral Aneurysm
Part of interventional neuroradiology procedures for the treatment of selected cerebral aneurysms are now based on stenting. To reduce thromboembolic events, dual antiplatelet therapy (APT) combining aspirin and clopidogrel is…
- Trial name
- TIC-TAC (NCT02675205)
- Testing
- Clopidogrel, Ticagrelor, aspirin
- Where
- France
- Volunteers
- 100 people
- Sponsor
- Fondation Ophtalmologique Adolphe de Rothschild
Aneurysm Cerebral
Kaneka Endovascular Embolization and Protection
Prospective, multi-center, non-randomized registry / study, up to 164 patients enrolled and followed at 180 days +/- 45 days and again at 365 days +/- 90 days post procedure
- Trial name
- KEEP (NCT05563051)
- Testing
- i-ED COIL
- Where
- 4 sites in United States
- Volunteers
- 164 people
- Sponsor
- Kaneka Medical America LLC
ANEURYSM CORONARY ARTERY
Trial to Assess the Efficacy of Combination Formula of Aspirin Plus Clopidogrel in Patients With Coronary Stent
The purpose of this study in to evaluate efficacy and tolerability of Clopirin and clopidogrel with aspirin in Korean Patients with post-percutaneous coronary artery intervention.
- Trial name
- NCT02410083
- Testing
- Clopirin 1, Clopidogrel-Aspirin(co-administration) 1, Clopirin 2
- Volunteers
- 448 people
- Sponsor
- Jeil Pharmaceutical Co., Ltd.
HIV Infections
Blood Vessel Function in HIV-Infected Patients Taking Anti-HIV Drugs
This is a substudy of ACTG A5142. The purpose of this substudy is to evaluate blood vessel function in HIV-infected patients taking anti-HIV drugs.
- Trial name
- NCT00050908
- Where
- 9 sites in United States
- Volunteers
- 75 people
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
Coronary Artery Ectasia
Endothelial Function in Patients With Ectatic Compared to Normal Coronary Arteries
The aim of this study is to show the frequency of endothelial dysfunction in patients suffering from ectatic coronary arteries as compared to those who have normal coronary arteries.
- Trial name
- NCT00548457
- Where
- Israel
- Volunteers
- 76 people, healthy volunteers welcome
- Sponsor
- Sheba Medical Center
Aortic Aneurysm and Dissection
Outcomes of Left Subclavian Artery Revascularization Strategies During Zone 2 Thoracic Endovascular Aortic Repair
Intentional coverage of left subclavian artery (LSA) is often necessary during thoracic endovascular aortic repair (TEVAR) to secure an adequate proximal landing zone.
- Trial name
- NCT07697820
- Testing
- Bypass graft
- Volunteers
- 50 people
- Sponsor
- Assiut University
Coronary Artery Ectasia
Safety And Efficacy Results of Percutaneous Renal Stent Implantation in Ectatic and Aneurysmatic Coronary Arteries
The aim of this study was to evaluate the efficacy and safety of renal stents implanted in ectatic/aneurysmatic coronary arteries.
- Trial name
- NCT05410678
- Testing
- Renal stent
- Volunteers
- 63 people
- Sponsor
- Bursa Postgraduate Hospital
Unruptured Intracranial Aneurysms, Cerebrovascular Event
Efficacy and Safety of Methylprednisolone After Flow-Diverter Stent Implantation in Unruptured Intracranial Aneurysms
Study Title: Testing Methylprednisolone to Prevent Strokes After a Stent Procedure for Brain Aneurysms What is the purpose of this study? This study aims to find out if a short course of a steroid medicine called…
- Conditions
- Unruptured Intracranial Aneurysms, Cerebrovascular Event, Hemorrhagic Stroke, Methylprednisolone
- Trial name
- NCT07353749
- Testing
- Methylprednisolone (Injectable Form)
- Where
- China
- Volunteers
- 864 people
- Sponsor
- Duan Chuanzhi
Intracranial Aneurysm
A Feasibility Study to Evaluate the Safety and Effectiveness of Implantation of Flowise Cerebral Flow Diverter (Flowise)
The purpose of this study is to evaluate the safety and short-term effectiveness of implantation of 'Flowise Cerebral Flow Diverter' for the treatment of unruptured wide-necked cerebral aneurysm in the internal carotid artery.
- Trial name
- NCT02609867
- Testing
- Flowise Cerebral Flow Diverter
- Where
- South Korea
- Volunteers
- 10 people
- Sponsor
- Yonsei University
Intracranial Aneurysm, Ruptured Aneurysm
EvaLuate EndoVascular Treatment of Acutely Ruptured Shallow Intradural Aneurysms With the Pipeline™ Flex Embolization Device With Shield TEchnology™ (ELEVATE)
The purpose of the study is to assess the safety and effectiveness of the Pipeline™ Flex Embolization Device with Shield Technology™ in the treatment with acutely ruptured intracranial aneurysms.
- Trial name
- ELEVATE (NCT04391803)
- Testing
- Pipeline™ Flex Embolization Device with Shield Technology™
- Where
- 7 sites in United States
- Volunteers
- 25 people
- Sponsor
- Medtronic Neurovascular Clinical Affairs
Intracranial Aneurysms, Peripheral Aneurysms
Study of the Penumbra Coil 400 System to Treat Aneurysm
This is a prospective, multi-center study of patients with intracranial or peripheral aneurysms who are treated by the PC 400 System.
- Trial name
- ACE (NCT01465841)
- Testing
- PC 400 coils (Penumbra )
- Where
- 6 sites in United States
- Volunteers
- 517 people
- Sponsor
- Penumbra Inc.
Cardiac Surgery, Coronary Artery Bypass
An Trial of Two Dosing Regimens of AP214 for the Prevention of Kidney Injury in Patients Undergoing Cardiac Surgery
This study investigates the effect of two dose-levels of AP214 on the prevention of (acute) kidney injury after cardiac surgery.
- Conditions
- Cardiac Surgery, Coronary Artery Bypass, Aortic Aneurysm, Valve Surgery
- Trial name
- NCT01256372
- Testing
- AP214
- Where
- Denmark
- Volunteers
- 77 people
- Sponsor
- Action Pharma A/S
Intracranial Aneurysm
MAXimizing Flow Diversion Effect On the Treatment of Large Intracranial Aneurysms With Embolization Devices
Investigate the ability of the intra-operative, intra-aneurysmal flow evaluation to assist with the treatment of intracranial large aneurysms using Embolization Device(s)
- Trial name
- MAX-PIPE (NCT03161769)
- Testing
- Neurovascular treatment of intracranial aneurysms, AneurysmFlow image processing software
- Where
- Canada
- Volunteers
- 30 people
- Sponsor
- University Health Network, Toronto
Coronary Arteriosclerosis
Dietary Nitrate and Nitrite to Increase Nitric Oxide in Patients With Coronary Artery Disease
This study will determine whether dietary nitrates and nitrites can produce nitric oxide in the body and dilate blood vessels in patients with coronary artery disease.
- Trial name
- NCT00069654
- Testing
- Forearm blood flow study, Brachial artery reactivity study, Treadmill exercise test
- Where
- United States
- Volunteers
- 42 people
- Sponsor
- National Heart, Lung, and Blood Institute (NHLBI)
Aneurysm, Dissection
PANTHER Study of Terumo Aortic Knitted and Woven Grafts, and Cardiovascular Patches
The purpose of this registry is to collect safety and performance data on all commercially available Terumo Aortic knitted and woven grafts, and cardiovascular patches in standard clinical practice.
- Conditions
- Aneurysm, Dissection, Aortic Root Aneurysm, Aortic Root Dissection
- Trial name
- PANTHER (NCT04545502)
- Testing
- Gelsoft Plus Vascular Graft, Vascular Bypass Graft, Cardiovascular Patch
- Where
- 30 sites in United States, Belgium and 4 more
- Volunteers
- 2,000 people
- Sponsor
- Vascutek Ltd.
Vertebral Artery Dissection, Traumatic, Neck Pain
Effects of Spinal Manipulation on Vertebrobasilar and Internal Carotis Arteries in Healthy Population
After lumbar pain, neck pain is the most common cause of patients needing chiropractic care; the second most common cause of spinal manipulation use (1).
- Trial name
- NCT03435159
- Testing
- Doppler Ultrasonography, Manual Chiropractic Spinal Manipulation, Instrumental Chiropractic Spinal Manipulation
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Bahçeşehir University